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Principlesofcleftlipandpalateformation
Ahmed Abdulwahab (1330095)
Firas Ahmed Saadallah
(1330074)
• Genetics factor
Chromosomal, Single gene,
Multifactorial – oral clefts, Mitochondrial
• Syndromes
Treacher Collins Syndrome
Hardikar syndrome
Fetal alcohol syndrome
• Environmental factors
Maternal smoking or tobacco exposure
Viral infections
Poor nutrition
Certain Medicinal drugs
Teratogens like
PREDISPOSING FACTORS
High maternal age
Diabetes
Toxemia
Reduced blood supply
Folic acid deficiency
Radiations
FEEDING PROBLEMS
THANKYOU
FORYOUR ATTENTION

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Principles of cleft lip and palate formation