Definition Etiology Clinical Features The metastasis Histopathology Treatment

1. quamous Cell Carcinoma

2. Definition

3. Etiology
Oral Squamous Cell Carcinoma Extrinsic Factors
 Tobacco Smoke
 Alcohol
 (for vermilion cancers only) Sunlight
 SmokelessTobacco
 Betel Quid (Paan)
 Alcohol
 Occupational Exposures & Pollutants
 Radiation
Intrinsic Factors
Systemic or generalized states
 Malnutrition
 Iron-deficiency Anemia
 Dyskeratosis Congenita
 Vitamin/Mineral Deficiencies
 Bacteria
 Candida
 Oncogenic Viruses
 Immunosuppression

4. Clinical Features

5. Clinical Features
exophytic lesion
 An Endophytic growth pattern - central,
depressed, irregularly shaped ulcer with a
surrounding “rolled” border of pink, red, or
white mucosa.
 Destruction of underlying bone, when present,
may be painful or completely painless

6. Clinical Features
• Leukoplakic
• Erythroplakic
• Erythroleukoplakic
The leukoplakic and erythroplakic examples
are probably early cases that have not yet
produced a mass or ulceration.

7. The metastasis

8. Histopathology

9. Treatment
Small
lesionsLarge
lesions

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