Press Release to international news media outlets on findings of pain disparities between Caucasian and Non-Caucasian women with metastatic breast cancer in 19 countries.
Clinical Trials for Ovarian Cancer: Fact vs. Fictionbkling
Courtney Hudson, CEO & Co-Founder of EmergingMed, explains the basics of clinical trials and the process of developing new treatments in the emerging age of personalized medicine and immunotherapy. Lean how to identify appropriate clinical trials, find strategies to determine your best options, and figure out which questions to ask when making your decisions. Watch the accompanying webinar: https://vimeo.com/203510985
Clinical Trials for Ovarian Cancer: Fact vs. Fictionbkling
Courtney Hudson, CEO & Co-Founder of EmergingMed, explains the basics of clinical trials and the process of developing new treatments in the emerging age of personalized medicine and immunotherapy. Lean how to identify appropriate clinical trials, find strategies to determine your best options, and figure out which questions to ask when making your decisions. Watch the accompanying webinar: https://vimeo.com/203510985
A diagnosis of DCIS often brings mixed messages. Is this a real breast cancer? What is the meaning of Stage 0? If this is not life threatening, why are the treatments similar to those recommended for an invasive cancer? Deborah Collyar, founder of Patient Advocates in Research, helps us interpret the new findings that will aid you in navigating this diagnosis.
26th International Papillomavirus Conference: Satellite Symposium
Enhancing HPV Prevention among Indigenous Populations: International Perspectives on Health and Well-Being
Montreal, Quebec
July 5, 2010
Panel 1 , Researching the Burden of HPV Disease, Immunization, and Cervical Screening among Indigenous Populations.
What Black Women Need to Know About Endometrial Cancerbkling
Dr. Kemi Doll, gynecologic oncologist at the University of Washington Medical Center, shares her passion for improving the lives of black women affected by this disease through her extensive research and knowledge about endometrial cancer.
This webinar is being put on in partnership with ECANA.
Radiotherapy and Immunotherapy Improve Metastatic Lung Cancer OutcomesLaura Lyn Jacimore
A radiation oncologist, Laura Lyn Jacimore works at UNC Nash Health Care System in Rocky Mount, North Carolina, where she consults with physicians to administer radiotherapy treatments to people with cancer. Laura Lyn Jacimore is also a member of the American Society of Therapeutic Radiation Oncology (ASTRO), and regularly attends its annual meetings.
Colonoscopy Screening for Special Populationsalizain416
In a series of testimonials, a myriad of patients, previously diagnosed with colon cancer or not, defend the importance of getting Colonoscopy Screened.
For More detail Visit link below
http://gastrosymptoms.com/colonoscopy-screening-special-populations/
My senior thesis, advised by Dr. Jodi Evans, which was selected for publication. My work focused on the review of pancreatic cancer and how other cancers with awareness campaigns had much improved prognoses.
A diagnosis of DCIS often brings mixed messages. Is this a real breast cancer? What is the meaning of Stage 0? If this is not life threatening, why are the treatments similar to those recommended for an invasive cancer? Deborah Collyar, founder of Patient Advocates in Research, helps us interpret the new findings that will aid you in navigating this diagnosis.
26th International Papillomavirus Conference: Satellite Symposium
Enhancing HPV Prevention among Indigenous Populations: International Perspectives on Health and Well-Being
Montreal, Quebec
July 5, 2010
Panel 1 , Researching the Burden of HPV Disease, Immunization, and Cervical Screening among Indigenous Populations.
What Black Women Need to Know About Endometrial Cancerbkling
Dr. Kemi Doll, gynecologic oncologist at the University of Washington Medical Center, shares her passion for improving the lives of black women affected by this disease through her extensive research and knowledge about endometrial cancer.
This webinar is being put on in partnership with ECANA.
Radiotherapy and Immunotherapy Improve Metastatic Lung Cancer OutcomesLaura Lyn Jacimore
A radiation oncologist, Laura Lyn Jacimore works at UNC Nash Health Care System in Rocky Mount, North Carolina, where she consults with physicians to administer radiotherapy treatments to people with cancer. Laura Lyn Jacimore is also a member of the American Society of Therapeutic Radiation Oncology (ASTRO), and regularly attends its annual meetings.
Colonoscopy Screening for Special Populationsalizain416
In a series of testimonials, a myriad of patients, previously diagnosed with colon cancer or not, defend the importance of getting Colonoscopy Screened.
For More detail Visit link below
http://gastrosymptoms.com/colonoscopy-screening-special-populations/
My senior thesis, advised by Dr. Jodi Evans, which was selected for publication. My work focused on the review of pancreatic cancer and how other cancers with awareness campaigns had much improved prognoses.
Oncologist briefing given by Dr. Castel as Principal Investigator of the Breast Cancer Adjuvant Therapy prospective longitudinal study (NCT00954564) to communicate interim results and help oncologists identify and refer eligible breast cancer patients into the longitudinal cohort study. The goal of this presentation was to help achieve study enrollment targets.
SUO_HCM4004_W2_A2_Estevez_Maria.docxby Maria Estevez.docxpicklesvalery
SUO_HCM4004_W2_A2_Esteve
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by Maria Estevez
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SUO_HCM4004_W2_A2_Estevez_Maria.docx
ORIGINALITY REPORT
PRIMARY SOURCES
Submitted to EDMC
St udent Paper
A. Clements. "Diagnosed with breast cancer
while on a f amily history screening programme:
an exploratory qualitative study.", European
Journal of Cancer Care/09615423, 20080501
Publicat ion
Submitted to Walden University
St udent Paper
P Hopwood. "Surviving breast cancer: can
women expect to 'get back to normal'?", Breast
Cancer Research, 2008
Publicat ion
orca.cf .ac.uk
Int ernet Source
SUO_HCM4004_W2_A2_Estevez_Maria.docxby Maria EstevezSUO_HCM4004_W2_A2_Estevez_Maria.docxORIGINALITY REPORTPRIMARY SOURCES
Diagnosed with breast cancer while on a family history
screening programme: an exploratory qualitative study
A. CLEMENTS, bsc, senior research nurse, Cancer Research UK Primary Care Education Research Group,
University of Oxford, Department of Primary Health Care, Oxford, B.J. HENDERSON, phd, research psycholo-
gist, Institute of Medical & Social Care Research, Ardudwy, Normal Site, University of Wales, Bangor, Gwynedd,
S. TYNDEL, ba, research officer, Cancer Research UK Primary Care Education Research Group, University of
Oxford, Department of Primary Health Care, Oxford, G. EVANS, md frcp, consultant in medical genetics,
Department of Clinical Genetics, St Mary’s Hospital, Manchester, K. BRAIN, phd, senior research fellow,
Institute of Medical Genetics, University of Wales College of Medicine, Heath Park, Cardiff, J. AUSTOKER, phd,
director, Cancer Research UK Primary Care Education Research Group, University of Oxford, Department of
Primary Health Care, Oxford, & E. WATSON, phd, deputy director, Cancer Research UK Primary Care Educa-
tion Research Group, University of Oxford, Department of Primary Health Care, Oxford, UK for the PIMMS Study
Management Group*
CLEMENTS A., HENDERSON B.J., TYNDEL S., EVANS G., BRAIN K., AUSTOKER J. & WATSON E. FOR
THE PIMMS STUDY MANAGEMENT GROUP (2008) European Journal of Cancer Care 17, 245–252
Diagnosed with breast cancer while on a family history screening programme: an exploratory qualitative study
Mammographic screening is offered to many women under 50 in the UK who are at moderate or high risk of
developing breast cancer because of their family history of the disease. Little is understood about the impact
of screening on the emotional well-being of women with a family history of breast cancer. This qualitative
study explores the value that women at increased risk placed on screening, both pre- and post-cancer diagnosis
and the impact of the diagnosis. In-depth inte ...
Diagnosed with breast cancer while on a family historyscreen.docxduketjoy27252
Diagnosed with breast cancer while on a family history
screening programme: an exploratory qualitative study
A. CLEMENTS, bsc, senior research nurse, Cancer Research UK Primary Care Education Research Group,
University of Oxford, Department of Primary Health Care, Oxford, B.J. HENDERSON, phd, research psycholo-
gist, Institute of Medical & Social Care Research, Ardudwy, Normal Site, University of Wales, Bangor, Gwynedd,
S. TYNDEL, ba, research officer, Cancer Research UK Primary Care Education Research Group, University of
Oxford, Department of Primary Health Care, Oxford, G. EVANS, md frcp, consultant in medical genetics,
Department of Clinical Genetics, St Mary’s Hospital, Manchester, K. BRAIN, phd, senior research fellow,
Institute of Medical Genetics, University of Wales College of Medicine, Heath Park, Cardiff, J. AUSTOKER, phd,
director, Cancer Research UK Primary Care Education Research Group, University of Oxford, Department of
Primary Health Care, Oxford, & E. WATSON, phd, deputy director, Cancer Research UK Primary Care Educa-
tion Research Group, University of Oxford, Department of Primary Health Care, Oxford, UK for the PIMMS Study
Management Group*
CLEMENTS A., HENDERSON B.J., TYNDEL S., EVANS G., BRAIN K., AUSTOKER J. & WATSON E. FOR
THE PIMMS STUDY MANAGEMENT GROUP (2008) European Journal of Cancer Care 17, 245–252
Diagnosed with breast cancer while on a family history screening programme: an exploratory qualitative study
Mammographic screening is offered to many women under 50 in the UK who are at moderate or high risk of
developing breast cancer because of their family history of the disease. Little is understood about the impact
of screening on the emotional well-being of women with a family history of breast cancer. This qualitative
study explores the value that women at increased risk placed on screening, both pre- and post-cancer diagnosis
and the impact of the diagnosis. In-depth interviews were undertaken with 12 women, aged 35–50, diagnosed
with breast cancer while on an annual mammographic screening programme. Women described the strong
sense of reassurance gained from screening prior to diagnosis. This faith in screening was reinforced by early
detection of their cancer. Reactions to diagnosis ranged from devastation to relief at having finally developed
a long-expected condition. Despite their positive attitudes about screening, not all women wanted to continue
with surveillance. For some, prophylactic mastectomy was preferable, to reduce future cancer risk and to
alleviate anxieties about the detection of another cancer at each subsequent screen. This study illustrates the
positive yet diverse attitudes towards mammographic screening in this group of women with a family history
of breast cancer.
Keywords: breast cancer, early screening programme, family history, qualitative.
Correspondence address: Alison Clements, Cancer Research UK Primary Care Education Research Group, University of Oxford, Department of Pr.
Diagnosed with breast cancer while on a family historyscreen.docxlynettearnold46882
Diagnosed with breast cancer while on a family history
screening programme: an exploratory qualitative study
A. CLEMENTS, bsc, senior research nurse, Cancer Research UK Primary Care Education Research Group,
University of Oxford, Department of Primary Health Care, Oxford, B.J. HENDERSON, phd, research psycholo-
gist, Institute of Medical & Social Care Research, Ardudwy, Normal Site, University of Wales, Bangor, Gwynedd,
S. TYNDEL, ba, research officer, Cancer Research UK Primary Care Education Research Group, University of
Oxford, Department of Primary Health Care, Oxford, G. EVANS, md frcp, consultant in medical genetics,
Department of Clinical Genetics, St Mary’s Hospital, Manchester, K. BRAIN, phd, senior research fellow,
Institute of Medical Genetics, University of Wales College of Medicine, Heath Park, Cardiff, J. AUSTOKER, phd,
director, Cancer Research UK Primary Care Education Research Group, University of Oxford, Department of
Primary Health Care, Oxford, & E. WATSON, phd, deputy director, Cancer Research UK Primary Care Educa-
tion Research Group, University of Oxford, Department of Primary Health Care, Oxford, UK for the PIMMS Study
Management Group*
CLEMENTS A., HENDERSON B.J., TYNDEL S., EVANS G., BRAIN K., AUSTOKER J. & WATSON E. FOR
THE PIMMS STUDY MANAGEMENT GROUP (2008) European Journal of Cancer Care 17, 245–252
Diagnosed with breast cancer while on a family history screening programme: an exploratory qualitative study
Mammographic screening is offered to many women under 50 in the UK who are at moderate or high risk of
developing breast cancer because of their family history of the disease. Little is understood about the impact
of screening on the emotional well-being of women with a family history of breast cancer. This qualitative
study explores the value that women at increased risk placed on screening, both pre- and post-cancer diagnosis
and the impact of the diagnosis. In-depth interviews were undertaken with 12 women, aged 35–50, diagnosed
with breast cancer while on an annual mammographic screening programme. Women described the strong
sense of reassurance gained from screening prior to diagnosis. This faith in screening was reinforced by early
detection of their cancer. Reactions to diagnosis ranged from devastation to relief at having finally developed
a long-expected condition. Despite their positive attitudes about screening, not all women wanted to continue
with surveillance. For some, prophylactic mastectomy was preferable, to reduce future cancer risk and to
alleviate anxieties about the detection of another cancer at each subsequent screen. This study illustrates the
positive yet diverse attitudes towards mammographic screening in this group of women with a family history
of breast cancer.
Keywords: breast cancer, early screening programme, family history, qualitative.
Correspondence address: Alison Clements, Cancer Research UK Primary Care Education Research Group, University of Oxford, Department of Pr.
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This PDF provides the majority of my slides from the statewide Minnesota Cancer Summit from February 28, 2019. The presentation focuses on Clinical Cancer Advances as published and released by consensus expert panels from The American Society of Clinical Oncology (@ASCO).
Many people wonder whether a cancer patient's attitude or personality type can impact their prognosis. In this SlideShare, Dana Nolan, a Mental Health Counselor, takes a closer look at how personality, attitude and cancer relate for our August 2016 support group session.
Assignment 2 Final Project Part III Designing a StudyYou are t.docxrock73
Assignment 2: Final Project Part III: Designing a Study
You are the hospital administrator in a medium-sized, urban, for-profit hospital that caters to middle-income groups. You wonder if patients' satisfaction with the hospital stay will increase significantly if they are given better and more flexible meal options. You decide to conduct a research study to find the answer. The first step is to design the study.
Design a descriptive study to investigate if better meal options will increase patient satisfaction. Include the following elements of design:
1. Develop a research question or purpose of the study
2. Selection of subjects for study (what is the sample)
3. Assignment of subjects to experimental or control groups
4. Study time period
5. Type of data to be gathered
6. Measures of meal options and of patient satisfaction
7. Method of data collection
8. Guidelines for data interpretation
After you complete building the study design, list three design elements you considered in your study that were not readily obvious in the one you read last week “Diagnosed with Breast Cancer While on a Family History Screening Programme: An Exploratory Qualitative Study.”
By Tuesday, February 21, 2017, submit your study design and list of three identified design elements in a Word document to the W3: Assignment 2 Dropbox.
Diagnosed with breast cancer while on a family history
screening programme: an exploratory qualitative study
A. CLEMENTS, bsc, senior research nurse, Cancer Research UK Primary Care Education Research Group,
University of Oxford, Department of Primary Health Care, Oxford, B.J. HENDERSON, phd, research psycholo-
gist, Institute of Medical & Social Care Research, Ardudwy, Normal Site, University of Wales, Bangor, Gwynedd,
S. TYNDEL, ba, research officer, Cancer Research UK Primary Care Education Research Group, University of
Oxford, Department of Primary Health Care, Oxford, G. EVANS, md frcp, consultant in medical genetics,
Department of Clinical Genetics, St Mary’s Hospital, Manchester, K. BRAIN, phd, senior research fellow,
Institute of Medical Genetics, University of Wales College of Medicine, Heath Park, Cardiff, J. AUSTOKER, phd,
director, Cancer Research UK Primary Care Education Research Group, University of Oxford, Department of
Primary Health Care, Oxford, & E. WATSON, phd, deputy director, Cancer Research UK Primary Care Educa-
tion Research Group, University of Oxford, Department of Primary Health Care, Oxford, UK for the PIMMS Study
Management Group*
CLEMENTS A., HENDERSON B.J., TYNDEL S., EVANS G., BRAIN K., AUSTOKER J. & WATSON E. FOR
THE PIMMS STUDY MANAGEMENT GROUP (2008) European Journal of Cancer Care 17, 245–252
Diagnosed with breast cancer while on a family history screening programme: an exploratory qualitative study
Mammographic screening is offered to many women under 50 in the UK who are at moderate or high risk of
developing breast cancer because of their family history of the disease. Little is understoo ...
Running head: CANCER 1
CANCER 16
Cancer
Amy L Joyner
Liberty University
Abstract
Diagnosis of cancer is associated with mental health. Caregivers should acknowledge the link that is present between body and mind when it comes to cancer, especially in women. Much attention with regards to this problem has been directed to medical treatment leaving out psychological treatment or interventions. This paper has the aim of looking at cancer in women from a psychological perspective. The patients discussed in this paper are women or female patients. Among the things that will be analyzed are current statistics with regard to cancer, psychological symptoms of cancer, its causes, its intervention or treatment, and biblical perspective of cancer.
Introduction
Popular accounts related to the experience of dealing with cancer in women are riveting. It portrays the image of disease that has a number of emotional and psychological needs of women and their families. Diagnosis of cancer is associated with mental health. Caregivers when dealing with women should acknowledge the link that is present between body and mind when it comes to cancer (Stanton, Rowland, & Ganz, 2015). The need to discover a medical treatment that is more effective has redirected a lot of focus from the search for better ways to help the psychological well-being of women. There has been a war of finding ways of doing aware with cancer since it has a profound effect on its patients, such as the women” (Stanton, Rowland, & Ganz, 2015, p. 159).
The situation with regards to cancer is gradually changing, especially in the recent years. Due to new discoveries and advancement in the field of cancer when it comes to treatment, screening technologies, and cancer detection, the group of long-term female cancer survivors has been going up rapidly. The increase in the number of these women survivors has changed the conception related to cancer as being an acute disease. Many people now term it a chronic disease. Due to the treatment that has been introduced, many women who once had the disease are showing “no evidence of disease” (Stanton, Rowland, & Ganz, 2015). Even with the treatment, their health together with their well-being states is still the same to individuals living with long-term, chronic concerns. This is because of lack of appropriate counseling given to these women to deal with psychological effects of cancer. The psychological needs of female cancer patients have been assumed by many. There are also other caregivers who do not understand the psychological needs of these cancer patients. They fail to recognize the psychological needs of these patients, and due to this, they inadequately address psychological symptoms of the dis ...
Similar to Press Release: Non caucasians at higher risk for severe metastatic breast cancer pain eurekalert science news (20)
- Video recording of this lecture in English language: https://youtu.be/kqbnxVAZs-0
- Video recording of this lecture in Arabic language: https://youtu.be/SINlygW1Mpc
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
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These lecture slides, by Dr Sidra Arshad, offer a quick overview of the physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar lead (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
6. Describe the flow of current around the heart during the cardiac cycle
7. Discuss the placement and polarity of the leads of electrocardiograph
8. Describe the normal electrocardiograms recorded from the limb leads and explain the physiological basis of the different records that are obtained
9. Define mean electrical vector (axis) of the heart and give the normal range
10. Define the mean QRS vector
11. Describe the axes of leads (hexagonal reference system)
12. Comprehend the vectorial analysis of the normal ECG
13. Determine the mean electrical axis of the ventricular QRS and appreciate the mean axis deviation
14. Explain the concepts of current of injury, J point, and their significance
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. Chapter 3, Cardiology Explained, https://www.ncbi.nlm.nih.gov/books/NBK2214/
7. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
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Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journey
Press Release: Non caucasians at higher risk for severe metastatic breast cancer pain eurekalert science news
1. PUBLIC RELEASE: 26-NOV-2007
Non-Caucasians at higher risk for severe
metastatic breast cancer pain
WILEY
A new study finds significant racial differences in the risk of pain related to metastatic breast cancer. An
analysis by Dr. Liana Castel of the University of North Carolina at Chapel Hill and colleagues found that
non-whites experience poorer pain control among women with this disease. The study is published in
the January 1, 2008 issue of CANCER, a peer-reviewed journal of the American Cancer Society.
Studies indicate that chronic or recurrent pain affects 30 percent of all cancer patients and 60 to 90
percent of patients with advanced cancer. Age, race, tumor type, genetics, psychosocial context, and
culture can all affect pain. However, it is unclear how pain is influenced by changes over the course of
disease due to factors including radiation, surgery, and chemotherapy. The current study was among
the first to examine whether race plays a role in patients' experiences in pain over the course of
metastatic cancer.
Dr. Castel and co-investigators studied 1,124 women with metastatic breast cancer and bone
metastases who received standard treatment in an international chemotherapy clinical trial conducted
from October 1998 to January 2001. The study comprised women in 19 countries; the majority (82%) of
non-whites were from the US. A test called the Brief Pain Inventory--which is based on a scale of zero to
ten in pain severity--was administered repeatedly over a year to determine pain levels. The authors
found that non-white women reached a pain level of seven or higher on the Brief Pain Inventory scale
significantly earlier during a year of follow-up, compared with white women. A score of 7 or higher on
the scale commonly designates severe (vs. moderate or mild) pain. Besides race, other predictors for
greater pain were inactive performance status and preceding radiation treatment.
Dr. Castel and her co-authors note that their findings confirm published evidence that non-Caucasians
are at highest risk for undertreatment of pain, including inadequate dosing and poor access to
medication. Racial/ethnic minority patients have also been shown to be at greater risk for breast cancer
mortality. The authors conclude that research should seek to uncover and resolve the reasons for these
racial disparities. In addition, "clinicians should use information about known risk factors to inform
more aggressive and earlier intervention among non-Caucasian women with metastatic breast cancer,"
say the authors.
###
This work was supported by AHRQ National Research Service Award Research Training Grant T32
HS000032-17. The authors also gratefully acknowledge Novartis Pharma for granting permission to
conduct these analyses.
2. Article: "Racial Difference in Pain During 1 Year Among Women With Metastatic Breast Cancer: A
Hazards Analysis of Interval-Censored Data," Liana D. Castel, Benjamin R. Saville, Venita DePuy, Paul A.
Godley, Katherine E. Hartmann, and Amy P. Abernethy, CANCER; Published Online: November 26, 2007
(DOI: 10.1002/cncr. 23133); Print Issue Date: January 1, 2008.
Contact: Ramona DuBose, University of North Carolina at Chapel Hill, 919-966-7467,
Ramona_DuBose@unc.edu
Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to
EurekAlert! by contributing institutions or for the use of any information through the EurekAlert
system.
Media Contact
Amy Molnar
amolnar@wiley.com
http://www.wiley.com/wiley-blackwell !
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Non-Caucasians at higher risk for severe metastatic breast cancer pain
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Study sheds new light on brain's source of power$
UNIVERSITY OF ROCHESTER MEDICAL CENTER