Pre-eclampsia is a condition that occurs in the second half of pregnancy or within 6 weeks of delivery. It causes high blood pressure and protein in the urine. Risk factors include a woman's first pregnancy, family history, previous pre-eclampsia, age over 40, or multiple babies. The cause is unclear but involves problems with the placenta. Signs include swelling, headaches, and abdominal pain. Management involves monitoring and delivering the baby early if severe, between 37-38 weeks. Untreated pre-eclampsia can lead to serious complications for both mother and baby.