2. Content
oIntroduction of nervous system
oOrganization of nervous system
oNervous tissue
oNeurons and its types
oSupporting cells
o Ascending tract and descending tract
oReflex
3. Introduction
• Nervous system is:
A physically connected network of cells, tissues and organs that allow
us to communicate with and react to the environment and perform
life activities.
Master controlling and communicating system
• Has two main division
• Central nervous system
• Peripheral nervous system
4. FOUR PRIMARY FUNCTIONS OF NERVOUS
SYSTEM
Sensing the world
Vision, Hearing, Smell, Taste,
Touch
Transmitting information
Processing information
Producing a response
5. Organization
A. Central Nervous System (CNS)
▫ Brain & spinal cord
▫ Integrative and control centers
-Receives, interprets and sends signals to PNS
B. Peripheral Nervous System (PNS)
▫ Nerves (31 pairs of spinal nerves,12 pairs of cranial nerves)
▫ Communication lines between CNS and rest of body
▫ Two Divisions:
1. Sensory (afferent) Division: Sensory receptors --
CNS
2. Motor (efferent) Division: CNS -- effectors (muscles &
glands)
6. Motor Division
• Somatic nervous system (voluntary)
- control skeletal muscles
• Autonomic nervous system (ANS) (involuntary)
– regulate smooth muscles, cardiac, glands
▫ Subdivisions:
o Sympathetic :
o“Fight or Flight”
oActivated during emergencies, exercise or vigorous physical activity
oRevs up body to respond to situations that upset homeostasis
o Parasympathetic:
o“Rest & Digest”
oReduces energy use
oPromotes:
o Storage of energy
o Elimination of wastes
o Homeostasis
7.
8.
9.
10. The mammalian brain is highly
complex, containing many
specialized regions that carry
out specific functions.
Generally, the brain is divided
into:
Hindbrain
Midbrain
Forebrain
THE COMPLEX BRAIN
11. Hindbrain
Medulla:
Controls autonomic functions.
Pons:
Controls sleep stages.
Cerebellum:
Coordinates movement, stores
some motor memory.
Helps maintain posture,
muscle control, and balance
12. Midbrain
• Located between the hindbrain and forebrain.
• All sensory and motor information that travels
between the forebrain and the spinal cord passes
through the midbrain
• making it a relay station for the central nervous
system.
• the “traffic cops” of the brain.
• Filters sensory input, which allows us to
concentrate.
• Filtering can be affected by higher thoughts.
13. Forebrain
Thalamus:
relay station channeling
sensory information.
Limbic system:
basic emotions, drives, and
behaviors.
Cortex:
higher thought
14. Limbic system
Hypothalamus:
Master controller of the
endocrine system.
Amygdala:
sensations of pleasure or
fear, recognition of fear in
others.
Hippocampus:
formation of memories.
Damage to these areas can lead to amnesia or
emotional disturbances
“controls: emotions and memories”
15. Cortex
Various areas :
control sensory
processing
motor control,
thought,
memory.
Top layer of the brain
Stores: experiences and/or learning
behavior & emotion
Sensory info
concerning touch
vision
memory & emotion,
speech and hearing
16. Spinal cord
• Grey matter
– mostly made up of cell bodies of neuron
• White matter
– composed of nerve fibers ( ascending and descending tracts )
embedded in neuroglial cells
17.
18. Nervous Tissue
1. Neurons (nerve cells)
• Functional unit of the nervous system
• Transmit message
Anatomy:
Cell body – contains nucleus; metabolic center
Dendrite – fiber that conveys messages toward cell body
Axon – conduct nerve impulses away from the cell body
Axon terminals – end of axon; contain neurotransmitters&
release them
Synaptic cleft/synapse – gap between neurons
22. Myelin
Whitish, fatty material that covers nerve fibers to
speed up nerve impulses
Schwann cells
Surround axons and form myelin sheath
Myelin sheath
• Tight coil of wrapped membranes
Nodes of Ranvier
Gaps between Schwann cells
23. • Ganglia: collections of cell bodies
• Bundles of nerve fibers = tracts (CNS) or nerves (PNS)
• White matter
• Dense collections of myelinated fibers
• Gray matter
• Unmyelinated fibers & cell bodies
• (nerve cell bodies, dendrites, axon terminals, bundles of
unmyelinated axons and neuroglia (gray color)
24. Dendrites receive signals.
The cell body integrates
signals.
The axon transmits action
potential. The myelin sheath
makes the signal travel
faster.
Synaptic terminals transmit
signals.
The Neuron
25. Neurons
• Neuron Function
• Irritability:
• ability to respond to stimulus & convert to
nerve impulse
• Conductivity:
• transmit impulse to other neurons,
muscles, or glands
• Classification of Neuron
• Functional Classification
• Structural Classification
26. 1. Functional Classification:
Direction nerve impulse is traveling
Sensory
neurons
Motor
neurons
Interneurons
carry impulses from
sensory receptors to
CNS
carry impulses from
CNS to muscles &
glands
connect sensory &
motor neurons
Vision, hearing,
equilibrium, taste,
smell, pain,
pressure, heat
27. 2. Structural Classification:
Processes extending from cell body
Multipolar Bipolar Unipolar
1 axon, several
dendrites
1 axon, 1 dendrite 1 process
Most common
(99%)
Rare
Short with 2
branches (sensory,
CNS)
Eg. Motor
neurons,
interneurons
Eg. retina, nose,
ear
Eg. PNS ganglia
28.
29. Nerve Impulses
• Cell membrane at rest = polarized
Na+outside cell, K+inside cell
Inside is (-) compared to outside
• Stimulus ---excited neuron (Na+rushes in)--
becomes depolarized
• Depolarization activates neuron to transmit an
action potential (nerve impulse)
All-or-none response
Impulse conducts down entire axon
• K+ diffuses out ---repolarization of membrane
• Na+/K+ ion concentrations restored by sodium-
potassium pump (uses ATP)
Exciting a Neuron
30.
31. References
• Elaine N. Marieb, Human Anatomy and Physiology 9th Edition .
• Dr. Henry Gray and Dr. Henry Vandyke Carter , Grays Anatomy
for Students 40th Edition.
• Various internet sources.
Editor's Notes
Glutamate -Sensory neurons and cerebral cortex
Acetylcholine (ACh) is an excitatory neurotransmitter secreted by motor neurons that innervate muscle cells, basal ganglia, preganglionic neurons of the autonomic nervous system, and postganglionic neurons of the parasympathetic and sympathetic nervous systems.