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Nervous System
Content
oIntroduction of nervous system
oOrganization of nervous system
oNervous tissue
oNeurons and its types
oSupporting cells
o Ascending tract and descending tract
oReflex
Introduction
• Nervous system is:
 A physically connected network of cells, tissues and organs that allow
us to communicate with and react to the environment and perform
life activities.
 Master controlling and communicating system
• Has two main division
• Central nervous system
• Peripheral nervous system
FOUR PRIMARY FUNCTIONS OF NERVOUS
SYSTEM
Sensing the world
Vision, Hearing, Smell, Taste,
Touch
Transmitting information
Processing information
Producing a response
Organization
A. Central Nervous System (CNS)
▫ Brain & spinal cord
▫ Integrative and control centers
-Receives, interprets and sends signals to PNS
B. Peripheral Nervous System (PNS)
▫ Nerves (31 pairs of spinal nerves,12 pairs of cranial nerves)
▫ Communication lines between CNS and rest of body
▫ Two Divisions:
1. Sensory (afferent) Division: Sensory receptors --
CNS
2. Motor (efferent) Division: CNS -- effectors (muscles &
glands)
Motor Division
• Somatic nervous system (voluntary)
- control skeletal muscles
• Autonomic nervous system (ANS) (involuntary)
– regulate smooth muscles, cardiac, glands
▫ Subdivisions:
o Sympathetic :
o“Fight or Flight”
oActivated during emergencies, exercise or vigorous physical activity
oRevs up body to respond to situations that upset homeostasis
o Parasympathetic:
o“Rest & Digest”
oReduces energy use
oPromotes:
o Storage of energy
o Elimination of wastes
o Homeostasis
 The mammalian brain is highly
complex, containing many
specialized regions that carry
out specific functions.
 Generally, the brain is divided
into:
 Hindbrain
 Midbrain
 Forebrain
THE COMPLEX BRAIN
Hindbrain
Medulla:
 Controls autonomic functions.
Pons:
 Controls sleep stages.
Cerebellum:
 Coordinates movement, stores
some motor memory.
 Helps maintain posture,
muscle control, and balance
Midbrain
• Located between the hindbrain and forebrain.
• All sensory and motor information that travels
between the forebrain and the spinal cord passes
through the midbrain
• making it a relay station for the central nervous
system.
• the “traffic cops” of the brain.
• Filters sensory input, which allows us to
concentrate.
• Filtering can be affected by higher thoughts.
Forebrain
Thalamus:
 relay station channeling
sensory information.
Limbic system:
 basic emotions, drives, and
behaviors.
Cortex:
 higher thought
Limbic system
Hypothalamus:
 Master controller of the
endocrine system.
Amygdala:
 sensations of pleasure or
fear, recognition of fear in
others.
Hippocampus:
 formation of memories.
Damage to these areas can lead to amnesia or
emotional disturbances
“controls: emotions and memories”
Cortex
 Various areas :
 control sensory
processing
 motor control,
 thought,
 memory.
Top layer of the brain
Stores: experiences and/or learning
behavior & emotion
Sensory info
concerning touch
vision
memory & emotion,
speech and hearing
Spinal cord
• Grey matter
– mostly made up of cell bodies of neuron
• White matter
– composed of nerve fibers ( ascending and descending tracts )
embedded in neuroglial cells
Nervous Tissue
1. Neurons (nerve cells)
• Functional unit of the nervous system
• Transmit message
Anatomy:
Cell body – contains nucleus; metabolic center
Dendrite – fiber that conveys messages toward cell body
Axon – conduct nerve impulses away from the cell body
Axon terminals – end of axon; contain neurotransmitters&
release them
Synaptic cleft/synapse – gap between neurons
Nervous Tissue
2. Supporting cells (Neuroglia)
CNS: astrocytes, microglia, ependymal cells,
oligodendrocytes
barrier between capillaries and neurons protect
neurons
immune/defense
line brain and spinal cord cavities wrap nerve
fibers
produces myelin sheaths (covering)
PNS: Schwann cells, satellite cells
surround large neurons protect & cushion
Myelin
 Whitish, fatty material that covers nerve fibers to
speed up nerve impulses
Schwann cells
 Surround axons and form myelin sheath
Myelin sheath
• Tight coil of wrapped membranes
Nodes of Ranvier
 Gaps between Schwann cells
• Ganglia: collections of cell bodies
• Bundles of nerve fibers = tracts (CNS) or nerves (PNS)
• White matter
• Dense collections of myelinated fibers
• Gray matter
• Unmyelinated fibers & cell bodies
• (nerve cell bodies, dendrites, axon terminals, bundles of
unmyelinated axons and neuroglia (gray color)
 Dendrites receive signals.
 The cell body integrates
signals.
 The axon transmits action
potential. The myelin sheath
makes the signal travel
faster.
 Synaptic terminals transmit
signals.
The Neuron
Neurons
• Neuron Function
• Irritability:
• ability to respond to stimulus & convert to
nerve impulse
• Conductivity:
• transmit impulse to other neurons,
muscles, or glands
• Classification of Neuron
• Functional Classification
• Structural Classification
1. Functional Classification:
Direction nerve impulse is traveling
Sensory
neurons
Motor
neurons
Interneurons
carry impulses from
sensory receptors to
CNS
carry impulses from
CNS to muscles &
glands
connect sensory &
motor neurons
Vision, hearing,
equilibrium, taste,
smell, pain,
pressure, heat
2. Structural Classification:
Processes extending from cell body
Multipolar Bipolar Unipolar
1 axon, several
dendrites
1 axon, 1 dendrite 1 process
Most common
(99%)
Rare
Short with 2
branches (sensory,
CNS)
Eg. Motor
neurons,
interneurons
Eg. retina, nose,
ear
Eg. PNS ganglia
Nerve Impulses
• Cell membrane at rest = polarized
 Na+outside cell, K+inside cell
 Inside is (-) compared to outside
• Stimulus ---excited neuron (Na+rushes in)--
becomes depolarized
• Depolarization activates neuron to transmit an
action potential (nerve impulse)
 All-or-none response
 Impulse conducts down entire axon
• K+ diffuses out ---repolarization of membrane
• Na+/K+ ion concentrations restored by sodium-
potassium pump (uses ATP)
Exciting a Neuron
References
• Elaine N. Marieb, Human Anatomy and Physiology 9th Edition .
• Dr. Henry Gray and Dr. Henry Vandyke Carter , Grays Anatomy
for Students 40th Edition.
• Various internet sources.

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  • 2. Content oIntroduction of nervous system oOrganization of nervous system oNervous tissue oNeurons and its types oSupporting cells o Ascending tract and descending tract oReflex
  • 3. Introduction • Nervous system is:  A physically connected network of cells, tissues and organs that allow us to communicate with and react to the environment and perform life activities.  Master controlling and communicating system • Has two main division • Central nervous system • Peripheral nervous system
  • 4. FOUR PRIMARY FUNCTIONS OF NERVOUS SYSTEM Sensing the world Vision, Hearing, Smell, Taste, Touch Transmitting information Processing information Producing a response
  • 5. Organization A. Central Nervous System (CNS) ▫ Brain & spinal cord ▫ Integrative and control centers -Receives, interprets and sends signals to PNS B. Peripheral Nervous System (PNS) ▫ Nerves (31 pairs of spinal nerves,12 pairs of cranial nerves) ▫ Communication lines between CNS and rest of body ▫ Two Divisions: 1. Sensory (afferent) Division: Sensory receptors -- CNS 2. Motor (efferent) Division: CNS -- effectors (muscles & glands)
  • 6. Motor Division • Somatic nervous system (voluntary) - control skeletal muscles • Autonomic nervous system (ANS) (involuntary) – regulate smooth muscles, cardiac, glands ▫ Subdivisions: o Sympathetic : o“Fight or Flight” oActivated during emergencies, exercise or vigorous physical activity oRevs up body to respond to situations that upset homeostasis o Parasympathetic: o“Rest & Digest” oReduces energy use oPromotes: o Storage of energy o Elimination of wastes o Homeostasis
  • 7.
  • 8.
  • 9.
  • 10.  The mammalian brain is highly complex, containing many specialized regions that carry out specific functions.  Generally, the brain is divided into:  Hindbrain  Midbrain  Forebrain THE COMPLEX BRAIN
  • 11. Hindbrain Medulla:  Controls autonomic functions. Pons:  Controls sleep stages. Cerebellum:  Coordinates movement, stores some motor memory.  Helps maintain posture, muscle control, and balance
  • 12. Midbrain • Located between the hindbrain and forebrain. • All sensory and motor information that travels between the forebrain and the spinal cord passes through the midbrain • making it a relay station for the central nervous system. • the “traffic cops” of the brain. • Filters sensory input, which allows us to concentrate. • Filtering can be affected by higher thoughts.
  • 13. Forebrain Thalamus:  relay station channeling sensory information. Limbic system:  basic emotions, drives, and behaviors. Cortex:  higher thought
  • 14. Limbic system Hypothalamus:  Master controller of the endocrine system. Amygdala:  sensations of pleasure or fear, recognition of fear in others. Hippocampus:  formation of memories. Damage to these areas can lead to amnesia or emotional disturbances “controls: emotions and memories”
  • 15. Cortex  Various areas :  control sensory processing  motor control,  thought,  memory. Top layer of the brain Stores: experiences and/or learning behavior & emotion Sensory info concerning touch vision memory & emotion, speech and hearing
  • 16. Spinal cord • Grey matter – mostly made up of cell bodies of neuron • White matter – composed of nerve fibers ( ascending and descending tracts ) embedded in neuroglial cells
  • 17.
  • 18. Nervous Tissue 1. Neurons (nerve cells) • Functional unit of the nervous system • Transmit message Anatomy: Cell body – contains nucleus; metabolic center Dendrite – fiber that conveys messages toward cell body Axon – conduct nerve impulses away from the cell body Axon terminals – end of axon; contain neurotransmitters& release them Synaptic cleft/synapse – gap between neurons
  • 19.
  • 20. Nervous Tissue 2. Supporting cells (Neuroglia) CNS: astrocytes, microglia, ependymal cells, oligodendrocytes barrier between capillaries and neurons protect neurons immune/defense line brain and spinal cord cavities wrap nerve fibers produces myelin sheaths (covering) PNS: Schwann cells, satellite cells surround large neurons protect & cushion
  • 21.
  • 22. Myelin  Whitish, fatty material that covers nerve fibers to speed up nerve impulses Schwann cells  Surround axons and form myelin sheath Myelin sheath • Tight coil of wrapped membranes Nodes of Ranvier  Gaps between Schwann cells
  • 23. • Ganglia: collections of cell bodies • Bundles of nerve fibers = tracts (CNS) or nerves (PNS) • White matter • Dense collections of myelinated fibers • Gray matter • Unmyelinated fibers & cell bodies • (nerve cell bodies, dendrites, axon terminals, bundles of unmyelinated axons and neuroglia (gray color)
  • 24.  Dendrites receive signals.  The cell body integrates signals.  The axon transmits action potential. The myelin sheath makes the signal travel faster.  Synaptic terminals transmit signals. The Neuron
  • 25. Neurons • Neuron Function • Irritability: • ability to respond to stimulus & convert to nerve impulse • Conductivity: • transmit impulse to other neurons, muscles, or glands • Classification of Neuron • Functional Classification • Structural Classification
  • 26. 1. Functional Classification: Direction nerve impulse is traveling Sensory neurons Motor neurons Interneurons carry impulses from sensory receptors to CNS carry impulses from CNS to muscles & glands connect sensory & motor neurons Vision, hearing, equilibrium, taste, smell, pain, pressure, heat
  • 27. 2. Structural Classification: Processes extending from cell body Multipolar Bipolar Unipolar 1 axon, several dendrites 1 axon, 1 dendrite 1 process Most common (99%) Rare Short with 2 branches (sensory, CNS) Eg. Motor neurons, interneurons Eg. retina, nose, ear Eg. PNS ganglia
  • 28.
  • 29. Nerve Impulses • Cell membrane at rest = polarized  Na+outside cell, K+inside cell  Inside is (-) compared to outside • Stimulus ---excited neuron (Na+rushes in)-- becomes depolarized • Depolarization activates neuron to transmit an action potential (nerve impulse)  All-or-none response  Impulse conducts down entire axon • K+ diffuses out ---repolarization of membrane • Na+/K+ ion concentrations restored by sodium- potassium pump (uses ATP) Exciting a Neuron
  • 30.
  • 31. References • Elaine N. Marieb, Human Anatomy and Physiology 9th Edition . • Dr. Henry Gray and Dr. Henry Vandyke Carter , Grays Anatomy for Students 40th Edition. • Various internet sources.

Editor's Notes

  1. Glutamate -Sensory neurons and cerebral cortex
  2. Acetylcholine (ACh) is an excitatory neurotransmitter secreted by motor neurons that innervate muscle cells, basal ganglia, preganglionic neurons of the autonomic nervous system, and postganglionic neurons of the parasympathetic and sympathetic nervous systems.