This document outlines a seminar presentation about positron emission tomography (PET) imaging of the prostate. It introduces PET imaging and its principles, discusses tracers used for prostate cancer imaging like 18F-FDG and 11C-choline, briefly describes prostate anatomy, and covers indications, contraindications, patient preparation, pros and cons of PET imaging as well as references.
https://www.snmclub.com/presentation
PET/MRI Current & Future Status
DALE BAILEY PhD , Principal Physicist
Departement of Nuclear Medicine, Royal North Shore Hospital
Professor in Medical Radiation Sciences, University of Sydney
Sydney, Australia
icrm2018
Role Of Integrated Pet-Ct In Cancer of Unknown PrimaryApollo Hospitals
Whilst earlier Whole body CT played an important role in detecting the primary site presently, Integrated Positron emission tomography (PET) and computed tomography (CT) can play an important role in patients with unknown primary as it combines the advantage of cross sectional imaging with the diagnostic advantages of PET.
USE OF PET – HEALTH CARE POLICY PERSPECTIVESRuby Med Plus
POSITRON EMISSION TOMOGRAPHY (PET) USE BY TERTIARY HEALTH CARE CENT RES AND ITS ACCESSIBILITY TO POPULATION: A POLICY PERSPECTIVE. a BRIEF Cost-Benefit analysis.
Indications to CTC are increasing
CTC is recommended in all cases of unfeasibility of colonoscopy
CTC is not ready for mass screening but is ideal for screening on an individual basis.
https://www.snmclub.com/presentation
PET/MRI Current & Future Status
DALE BAILEY PhD , Principal Physicist
Departement of Nuclear Medicine, Royal North Shore Hospital
Professor in Medical Radiation Sciences, University of Sydney
Sydney, Australia
icrm2018
Role Of Integrated Pet-Ct In Cancer of Unknown PrimaryApollo Hospitals
Whilst earlier Whole body CT played an important role in detecting the primary site presently, Integrated Positron emission tomography (PET) and computed tomography (CT) can play an important role in patients with unknown primary as it combines the advantage of cross sectional imaging with the diagnostic advantages of PET.
USE OF PET – HEALTH CARE POLICY PERSPECTIVESRuby Med Plus
POSITRON EMISSION TOMOGRAPHY (PET) USE BY TERTIARY HEALTH CARE CENT RES AND ITS ACCESSIBILITY TO POPULATION: A POLICY PERSPECTIVE. a BRIEF Cost-Benefit analysis.
Indications to CTC are increasing
CTC is recommended in all cases of unfeasibility of colonoscopy
CTC is not ready for mass screening but is ideal for screening on an individual basis.
Clinicians, Leveraging AI expertise, Understanding the
Regulatory Framework
• Clinical interpretability guiding the adoption of AI-first
differential diagnoses
• Disparity in data literacy affecting the communication of
AI among healthcare scientists
• Regulatory challenges impeding the penetration of AI
into clinical practice - from research to policymakers
Frank J. Rybicki MD, PhD, Professor and Chair, Department
of Radiology, UNIVERSITY OF OTTAWA FACULTY OF
MEDICINE
Role of Radiotherapy in HCC. What do the guidelines say ? A comprehensive review of guidelines and other studies on role of radiotherapy in hepatocellular carcinoma.
What is a Pet Scan : Nuclear 3-D imaging test that uses a radioactive substance called a tracer to look for disease in the body.
Shows how organs and tissues are working at a molecular and cellular level. Scan is non-invasive, but does involve exposure to ionizing radiation.
Best known for its role in detecting cancer imaging.
A small amount of a radioactive sugar molecule, 18 fluoro-2-deoxyglucose (FDG), is injected into the bloodstream (can also be inhaled as gas or swallowed in pill form).
A PET Scan is used to detect and generate images that indicate areas of high FDG uptake.
Many cancers require more energy than normal cells, and the FDG tracer accumulates in these cells.
This allows cancers to be seen on the Pet images as hot spots.
According to the World Health Organization (WHO) prostate cancer is the second cause of cancer death in men worldwide [1,2]. Some advanced prostate cancers have well known symptoms. However non-cancerous diseases of the prostate, such as benign prostatic hyperplasia (BPH) cause same symptoms. On the other hand, at very early stages, prostate cancer has no symptoms, the tumor dimension is quite small, and it is extremely difficult to detect it. If prostate cancer is detected at an early stage, it can be successfully cured by different methods. At the later stages, treatment or surgery has very low efficiency. Prostate cancer can often be found by measuring the amount of PSA in the blood. Most healthy men have levels under 4 nano-grams per milliliter (ng/mL) of blood. When prostate cancer develops, the PSA level usually goes above 4. However, for determination of the existence of cancer, some additional methods are used: for example: PSA velocity [3,4] and/or PSA density. Besides, measurement of the ratio of free to total PSA is additional tool in prostate cancer diagnosis [5]. However, the major drawback of PSA determination is its relative lack of specificity. The PSA level can also be increased by benign prostate hyperplasia (BPH) - a noncancerous enlargement of the prostate, prostatitis, etc.
(October 12, 2021) Webinar: Clinical Field MRI As A Measurement Instrument fo...Scintica Instrumentation
Watch our webinar where Professor Marc-Andre Fortin presented about the 3D printing of hydrogels and hydrated substances that have been introduced in various fields of biomedical research including regenerative medicine, cosmetic surgery, orthopedics, and medical physics.
However, one of the main challenges faced by 3D printing and bioprinting is geometrical conformity. In this presentation, studies requiring hydrogel 3D printing in the fields of ophthalmology, regenerative medicine, and medical physics, were described. MRI scanning procedures were developed and optimized for these specific applications.
The presentation highlighted the potential role of MRI in the development of more accurate, more precise 3D-printed hydrogel objects.
Clinicians, Leveraging AI expertise, Understanding the
Regulatory Framework
• Clinical interpretability guiding the adoption of AI-first
differential diagnoses
• Disparity in data literacy affecting the communication of
AI among healthcare scientists
• Regulatory challenges impeding the penetration of AI
into clinical practice - from research to policymakers
Frank J. Rybicki MD, PhD, Professor and Chair, Department
of Radiology, UNIVERSITY OF OTTAWA FACULTY OF
MEDICINE
Role of Radiotherapy in HCC. What do the guidelines say ? A comprehensive review of guidelines and other studies on role of radiotherapy in hepatocellular carcinoma.
What is a Pet Scan : Nuclear 3-D imaging test that uses a radioactive substance called a tracer to look for disease in the body.
Shows how organs and tissues are working at a molecular and cellular level. Scan is non-invasive, but does involve exposure to ionizing radiation.
Best known for its role in detecting cancer imaging.
A small amount of a radioactive sugar molecule, 18 fluoro-2-deoxyglucose (FDG), is injected into the bloodstream (can also be inhaled as gas or swallowed in pill form).
A PET Scan is used to detect and generate images that indicate areas of high FDG uptake.
Many cancers require more energy than normal cells, and the FDG tracer accumulates in these cells.
This allows cancers to be seen on the Pet images as hot spots.
According to the World Health Organization (WHO) prostate cancer is the second cause of cancer death in men worldwide [1,2]. Some advanced prostate cancers have well known symptoms. However non-cancerous diseases of the prostate, such as benign prostatic hyperplasia (BPH) cause same symptoms. On the other hand, at very early stages, prostate cancer has no symptoms, the tumor dimension is quite small, and it is extremely difficult to detect it. If prostate cancer is detected at an early stage, it can be successfully cured by different methods. At the later stages, treatment or surgery has very low efficiency. Prostate cancer can often be found by measuring the amount of PSA in the blood. Most healthy men have levels under 4 nano-grams per milliliter (ng/mL) of blood. When prostate cancer develops, the PSA level usually goes above 4. However, for determination of the existence of cancer, some additional methods are used: for example: PSA velocity [3,4] and/or PSA density. Besides, measurement of the ratio of free to total PSA is additional tool in prostate cancer diagnosis [5]. However, the major drawback of PSA determination is its relative lack of specificity. The PSA level can also be increased by benign prostate hyperplasia (BPH) - a noncancerous enlargement of the prostate, prostatitis, etc.
(October 12, 2021) Webinar: Clinical Field MRI As A Measurement Instrument fo...Scintica Instrumentation
Watch our webinar where Professor Marc-Andre Fortin presented about the 3D printing of hydrogels and hydrated substances that have been introduced in various fields of biomedical research including regenerative medicine, cosmetic surgery, orthopedics, and medical physics.
However, one of the main challenges faced by 3D printing and bioprinting is geometrical conformity. In this presentation, studies requiring hydrogel 3D printing in the fields of ophthalmology, regenerative medicine, and medical physics, were described. MRI scanning procedures were developed and optimized for these specific applications.
The presentation highlighted the potential role of MRI in the development of more accurate, more precise 3D-printed hydrogel objects.
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Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
These lecture slides, by Dr Sidra Arshad, offer a quick overview of physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar leads (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
MANAGEMENT OF ATRIOVENTRICULAR CONDUCTION BLOCK.pdfJim Jacob Roy
Cardiac conduction defects can occur due to various causes.
Atrioventricular conduction blocks ( AV blocks ) are classified into 3 types.
This document describes the acute management of AV block.
Anti ulcer drugs and their Advance pharmacology ||
Anti-ulcer drugs are medications used to prevent and treat ulcers in the stomach and upper part of the small intestine (duodenal ulcers). These ulcers are often caused by an imbalance between stomach acid and the mucosal lining, which protects the stomach lining.
||Scope: Overview of various classes of anti-ulcer drugs, their mechanisms of action, indications, side effects, and clinical considerations.
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Position electron emission on prostrate.pptx
1. POSITRON EMISSION TOMOGRAPHY (PET)
IMAGING OF THE PROSTATE
SEMINAR PRESENTATION
BY
AMINU AHMAD
1210713003
DEPARTMENT OF RADIOGRAPHY
FACULTY OF CLINICAL SCIENCE
COLLEGE OF HEALTH SCIENCES
USMANU DANFODIYO UNIVERSITY,SOKOTO
2. OUTLINE
• Introduction
• Principle of PET imaging
• Brief anatomy
• indications
• Contraindications
• Patient preparations
• Pros and cons
• References
3. INTRODUCTION
• PET is an imaging diagnostic tool to
observe metabolic and physiologic
processes of organs in their normal
and diseased states (Herzog and
lerche, 2016).
4. PRINCIPLE OF PET
• Positron emission tomography (PET)
involves intravenous injection of a
radioactive tracer into the human
body (Tai and Piccini, 2004).
11. PROS
• The scans can depict diseases before signs and
symptoms
• PET scans are a bit safer as the radiation
dosage one is exposed to is relatively low.
• Ability to differentiate benign and malignant
tumors
• Can be used as an alternative to biopsy ( Ayres
2018).
12. CONS
• The sensitivity is too high
• Its quite expensive compared to other imaging
modalities
• Exposure to radioactive rays which is not good
( Ayres 2018).
13. REFERENCES
Ayres, C. (2018) https://connectusfund.org/9-advantages-and-
disadvantages-of-pet-scans (Accessed May, 16 2019)
Bouchelouche, K., Turkbey, B., Choyke,P.,Capala,J.(2010) Imaging
prostate cancer:An update on positron emission tomography and
magnetic resonance imaging: 11(3):180-190
Bennett, T.,Oza,M. (2016). Diagnostic imaging:nuclear medicine 2nd
edition Elsevier:philadelphia
Daniel,A.,P.(2014) Nuclear medicine:Practical physics,artifacts and
pitfalls. Oxford:newyork 10
Herzog,H., Lerche,C.(2016). ‘Advances in clinical PET/MRI
instrumentation’PET Clinics 11(2), 95-103
14. REFERENCES
Kitson, S., L., Cuccurullo, V.,Ciarmiello,A., Salvo, D,.Mansi, L. (2009).
Clinical Applications of Positron Emission Tomography (PET) Imaging in
Medicine: Oncology, Brain Diseases and Cardiology. Current
Radiopharmaceuticals, 2:224-253
Lawrence, E.,W. (2019) Snell’s clinical anatomy by regions. 10th edition.
Wolters kluwer:philadelphia, 1103-1105
Ryan, S., McNicholas, M and Eustace, S (2011) Anatomy for diagnostic
imaging. 3rd edition. Elsevier;philadelpia 233-234
Tai, Y., F., Piccini, P.(2004). Apllication of positron emission
tomography(PET) in neurology
