This document provides key analytical applications to help laboratories address the pressing concerns of the changing global landscape. Specifically, Volume 9 includes applications for Energy & Industrial, Environmental, Food & Beverage, and Pharmaceuticals & Nutraceuticals and Forensics & Toxicology.
Spotlight on Analytical Applications e-Zine - Volume 2PerkinElmer, Inc.
This document provides key analytical applications to help laboratories address the pressing concerns of the changing global landscape. Specifically, Volume 2 includes applications for Energy, Environmental, Food & Beverage, Materials Characterization and Pharmaceuticals.
Nutrient Leaching and Groundwater Quality Assessment near Integrated Construc...Mawuli Dzakpasu
The document summarizes a study assessing nutrient leaching and groundwater quality near an integrated constructed wetland treating domestic wastewater. Key findings include:
1) The constructed wetland was very effective at removing nutrients like ammonia, nitrates, and phosphates from wastewater, achieving over 80% removal on average.
2) Leachate from the wetland cells contained high levels of ammonia but generally low levels of nitrates and phosphates.
3) Low infiltration rates from the wetland may not immediately threaten groundwater quality.
4) Groundwater nutrient levels were generally low except near sites with peat in the soil, which saw slightly elevated ammonia levels.
This document summarizes a research article that presents a novel biosensor for detecting nitrite based on a single-layer graphene nanoplatelet (SLGnP)-protein composite film. The composite film is created by combining SLGnP, tetrasodium 1,3,6,8-pyrenesulfonic acid (TPA), and myoglobin protein and casting it on a glassy carbon electrode. Characterization shows the protein retains its structure and there are strong electrostatic interactions between the components in the film. Electrochemical analysis demonstrates the composite film enhances the direct electron transfer of the protein and can catalytically reduce nitric oxide. The resulting biosensor exhibits high sensitivity, a low detection limit, good stability and reproducibility for
The document discusses biomarkers for assessing tobacco smoke exposure during pregnancy. It begins by listing some of the thousands of chemicals found in tobacco smoke and electronic databases containing this information. It then discusses selecting smoke components for analysis based on their chemical, toxicological and pharmacological profiles. The document specifically examines NNAL, a metabolite of the tobacco-specific nitrosamine NNK. It describes NNAL's structure and metabolism, as well as analytical methods for quantifying NNAL and its glucuronide conjugates in urine using LC-MS/MS. The goals are to develop sensitive and rapid assays to measure smoke exposure from different sources during pregnancy and its effects on mothers and newborns.
This document contains information about a 3 hour exam for an MBA/PGDBM Accounting for Management course. The exam contains 13 multiple choice questions worth 75 marks total, split into two sections. Section A is compulsory and contains 15 sub-questions worth 2 marks each. Section B contains 9 questions worth 5 marks each, and covers topics like accounting conventions, the role of accountants, target costing, financial statements, liquidity/solvency ratios, funds flow statements, and cost accounting among others. Sample questions include explaining the accounting cycle, calculating return on investment, and defining budgets and budgetary control.
This document provides guidelines for forming an International Women's Coffee Alliance (IWCA) Country Chapter. It outlines an 8-step process for chapter formation including building trust among local women in coffee, submitting a letter of intent, becoming a legally recognized non-profit organization, developing strategic plans, applying for IWCA recognition, signing a letter of understanding, using the IWCA logo, and annual reporting. It also discusses chapter operations such as membership, funding, projects, and financial responsibilities. The overall purpose is to empower women in coffee communities through local and global networking opportunities.
Spotlight on Analytical Applications e-Zine - Volume 2PerkinElmer, Inc.
This document provides key analytical applications to help laboratories address the pressing concerns of the changing global landscape. Specifically, Volume 2 includes applications for Energy, Environmental, Food & Beverage, Materials Characterization and Pharmaceuticals.
Nutrient Leaching and Groundwater Quality Assessment near Integrated Construc...Mawuli Dzakpasu
The document summarizes a study assessing nutrient leaching and groundwater quality near an integrated constructed wetland treating domestic wastewater. Key findings include:
1) The constructed wetland was very effective at removing nutrients like ammonia, nitrates, and phosphates from wastewater, achieving over 80% removal on average.
2) Leachate from the wetland cells contained high levels of ammonia but generally low levels of nitrates and phosphates.
3) Low infiltration rates from the wetland may not immediately threaten groundwater quality.
4) Groundwater nutrient levels were generally low except near sites with peat in the soil, which saw slightly elevated ammonia levels.
This document summarizes a research article that presents a novel biosensor for detecting nitrite based on a single-layer graphene nanoplatelet (SLGnP)-protein composite film. The composite film is created by combining SLGnP, tetrasodium 1,3,6,8-pyrenesulfonic acid (TPA), and myoglobin protein and casting it on a glassy carbon electrode. Characterization shows the protein retains its structure and there are strong electrostatic interactions between the components in the film. Electrochemical analysis demonstrates the composite film enhances the direct electron transfer of the protein and can catalytically reduce nitric oxide. The resulting biosensor exhibits high sensitivity, a low detection limit, good stability and reproducibility for
The document discusses biomarkers for assessing tobacco smoke exposure during pregnancy. It begins by listing some of the thousands of chemicals found in tobacco smoke and electronic databases containing this information. It then discusses selecting smoke components for analysis based on their chemical, toxicological and pharmacological profiles. The document specifically examines NNAL, a metabolite of the tobacco-specific nitrosamine NNK. It describes NNAL's structure and metabolism, as well as analytical methods for quantifying NNAL and its glucuronide conjugates in urine using LC-MS/MS. The goals are to develop sensitive and rapid assays to measure smoke exposure from different sources during pregnancy and its effects on mothers and newborns.
This document contains information about a 3 hour exam for an MBA/PGDBM Accounting for Management course. The exam contains 13 multiple choice questions worth 75 marks total, split into two sections. Section A is compulsory and contains 15 sub-questions worth 2 marks each. Section B contains 9 questions worth 5 marks each, and covers topics like accounting conventions, the role of accountants, target costing, financial statements, liquidity/solvency ratios, funds flow statements, and cost accounting among others. Sample questions include explaining the accounting cycle, calculating return on investment, and defining budgets and budgetary control.
This document provides guidelines for forming an International Women's Coffee Alliance (IWCA) Country Chapter. It outlines an 8-step process for chapter formation including building trust among local women in coffee, submitting a letter of intent, becoming a legally recognized non-profit organization, developing strategic plans, applying for IWCA recognition, signing a letter of understanding, using the IWCA logo, and annual reporting. It also discusses chapter operations such as membership, funding, projects, and financial responsibilities. The overall purpose is to empower women in coffee communities through local and global networking opportunities.
Spotlight on Analytical Applications e-Zine - Volume 10PerkinElmer, Inc.
This document provides key analytical applications to help laboratories address the pressing concerns of the changing global landscape. Specifically, Volume 10 includes applications for Energy & Industrial, Environmental, Food & Beverage, and Pharmaceuticals & Nutraceuticals.
Spotlight on Analytical Applications e-Zine – Volume 14PerkinElmer, Inc.
Spotlight on Applications is a quarterly compendium of recent applications, delivering a variety of topics that address the pressing issues and analytical challenges you may face today. Our e-zine covers a broad range of applications within various industries – all accessible online at your convenience.
PerkinElmer Application Note: Monitoring volatile organic compounds in beer p...PerkinElmer, Inc.
Beer is a popular beverage produced by the fermentation of hopped malt extracted from barley and other grains. Although simple in concept, beer is a highly complex mixture of many compounds including sugars, proteins, alcohols, esters, acids, ketones, acids and terpenes. Flavor is an important quality of any beer and the chemical content of the beer is obviously responsible for that flavor. Aroma is an extremely important part of the flavor and so there is a strong interest by brewers in the volatile organic compounds (VOCs) in beer that affect it's aroma. This application note describes a system comprising a headspace trap sampler to extract and concentrate VOCs from a beer sample and deliver them to a gas chromatograph/mass spectrometer (GC/MA) for separation, identification and quantification.
FTIR spectroscopy involves using infrared light to analyze materials. It works by passing infrared light through a sample and measuring the vibrations and rotations of molecules to determine chemical structure. Common applications of FTIR spectroscopy include identifying polymers, analyzing pharmaceuticals and contaminants, monitoring emissions, and performing quality control tests of materials.
PerkinElmer Spotlight on Analytical Applications e-Zine – Volume 16PerkinElmer, Inc.
Spotlight on Applications is a quarterly compendium of recent applications, delivering a variety of topics that address the pressing issues and analytical challenges you may face today. Our e-zine covers a broad range of applications within various industries – all accessible online at your convenience.
http://www.perkinelmerapplications.com/subscribe/
Spotlight on Analytical Applications e-Zine - Volume 13PerkinElmer, Inc.
This document provides key analytical applications to help laboratories address the pressing concerns of the changing global landscape. Specifically, Volume 13 includes applications for Consumer Products, Energy & Industrial, Environmental and Pharmaceuticals & Nutraceuticals.
synthesis and spectral studies on cardanol based polyurethanesINFOGAIN PUBLICATION
Cardanol is a renewable organic resource obtained as a byproduct from the cashew industry. The present study has been carried out with an aim to manufacture rigid polyurethanes from natural and eco – friendly sources due to the rising prices of petrochemicals and also as an environmental concern. Vegetable oil based polyurethanes promising a new generation polymers which are low cost materials in the family of polyurethanes. Cardanol based phenolic resin has been synthesized by condensing cardanol with furfural in a particular mole ratio using phthalic acid as catalyst. The progress of the reaction was monitored by determining the free furfural and free phenol content. The resin was cured by using the curing agent 4, 41 - methylene bis(cyclohexyl isocyanate) and the catalyst dibutyltin dilaurate to produce polyurethane. Polyurethanes are an important class of polymers that have found place in many applications. The physico chemical and spectral properties of resin and polyurethane have also been studied.
The document describes the analysis of acetone, n-hexane, MIBK, MIBC, and MNBK from a soil decontamination process using an Agilent 490 Micro GC. Steam is injected into polluted soil to evaporate contaminants, and the steam with contaminants is analyzed by the Micro GC. The Micro GC uses two columns, a CP-Sil 5 CB column and a CP-Wax 52 CB column, to separate the compounds of interest in the ppm range in the presence of air and moisture. The Micro GC provides lab-quality analysis of gas mixtures in a compact, portable device.
Analysis of Arsenic, Cadmium and Lead in Chinese Spice Mixtures using Graphit...PerkinElmer, Inc.
The objective of this work is two-fold: (1) to accurately
analyze the levels of toxic heavy metals like lead, cadmium
and arsenic that may be present in some major spice brands
available in the local markets in China, by using graphite
furnace atomic absorption spectrophotometry (GFAAS); (2)
to cross-reference these measured levels to the recommended limits specified by the U.S. FDA.
Learn more about our solutions: http://bit.ly/1iXLg0D
Physics Of A Magritek Nmr SpectrometerLaura Martin
The document discusses techniques used to identify an unknown compound, including NMR spectroscopy, IR spectroscopy, and mass spectrometry. NMR spectroscopy involves dissolving a sample in a deuterated solvent and obtaining a spectrum that shows proton or carbon chemical shifts. IR spectroscopy subjects molecules to infrared light which produces a spectrum indicating functional groups based on frequencies and transmittance. Mass spectrometry breaks molecules into ions and provides molecular mass information. These spectroscopy techniques are useful in pharmaceutical development for determining chemical and physical properties and identifying active ingredients.
This document provides an abstract for a report on ethylene production. It discusses commercial steam cracking technologies used to produce ethylene from naphtha, ethane/propane, including developing technologies like gas-to-ethylene. It examines the costs of producing ethylene from different feedstocks and regional supply and demand. The abstract outlines the major commercial technologies, developments in different regions, and provides an overview of the steam cracking process used for natural gas liquids and naphtha.
This document discusses elemental impurities in pharmaceuticals. It describes the method used to establish permitted daily exposures (PDEs) for elemental impurities, which involves deriving a PDE from toxicity studies in animals using modifying factors. It then lists the established PDEs for various elemental impurities according to their class. Finally, it discusses several instrumentation techniques for determining elemental impurities, including flame atomic absorption, electrothermal atomization, and hydride generation atomic absorption spectroscopy.
IOSRPHR(www.iosrphr.org) IOSR Journal of Pharmacyiosrphr_editor
This document summarizes a study analyzing the phytochemical constituents of Hybanthus enneaspermus using UV, FTIR, and GC-MS techniques. UV and FTIR analysis identified characteristic peaks indicating the presence of compounds like phenols, alcohols, acids, and aromatics. GC-MS identified 10 compounds in the ethanol extract including (5E,13E)-5,13-Docosadienoic acid and Cedran-diol, which have biological activities. The major findings provide insight into the bioactive compounds in H. enneaspermus with potential therapeutic applications.
IOSRPHR(www.iosrphr.org) IOSR Journal of Pharmacyiosrphr_editor
This document presents a study analyzing the phytochemical constituents of Hybanthus enneaspermus using UV, FTIR and GC-MS techniques. The UV and FTIR analysis identified various functional groups present in the plant's ethanol extract, including phenols, alcohols, alkanes and carboxylic acids. GC-MS analysis identified 10 compounds in the extract, with the major ones being (5E,13E)-5,13-Docosadienoic acid and Cedran-diol, which have antimicrobial and anti-inflammatory properties. The study characterized several bioactive compounds in H. enneaspermus with potential therapeutic applications.
The document is a newsletter from Spectro Group, a company that provides testing, calibration, training, inspection, R&D, and other services. The newsletter discusses electronic waste (e-waste) and how it contains precious metals like gold, silver, and palladium that can be recovered through recycling. It also summarizes Spectro's capabilities in analyzing e-waste to extract these precious metals. The newsletter provides additional details on Spectro's services and facilities.
Collagen and bone fat are important resources in the food industry. It is essential that these primary products are odor- and taste free. Extensive de-odourization processes are used during bone fat & collagen processing to eliminate any off-flavors that might be present. Regular sensory evaluation performed by specially trained panels in combination with GC-MS analysis ensures product quality is not compromised.
Bio Trak Importance Of Good Non Viable Measurements Us Cc 102 BStewart K. Jason
The document describes a new particle counter called the BIOTRAK Real-Time Viable Particle Counter. It can detect and count both viable and non-viable particles in real-time, addressing limitations of traditional particle counters. The counter meets regulatory standards for particle counting and sizing to allow comparison to historical non-viable particle data. It samples air at a high flow rate comparable to other samplers to optimize detection of contaminants. The counter separates particles, detects viability using laser fluorescence, and provides total and viable particle counts to help characterize cleanroom environments.
Toxic Trace Metals in Edible Oils by Graphite Furnace Atomic Absorption Spect...PerkinElmer, Inc.
"This method reports the development of a direct analysis
method for edible oil samples using GFAAS without digestion.
The advantages of using this method include small sample
volume, direct introduction of samples, high sensitivity, and
rapid analysis times. The application of GFAAS to arsenic,
lead and cadmium analysis in edible oils was performed.
The optimal pyrolysis and atomization temperatures, limit of detection, quality control (QC) checks and recoveries were studied in order to develop a rapid and accurate method.
Learn more about our solutions: http://bit.ly/1dqSYtg
O documento discute o uso do kit PlGF 1-2-3 da PerkinElmer para triagem da pré-eclâmpsia. O kit permite identificar mulheres com alto risco de pré-eclâmpsia no primeiro trimestre de forma sensível. Quando usado em conjunto com outros fatores, como histórico médico e pressão arterial, pode prever até 88% dos casos de pré-eclâmpsia precoce. O documento também descreve como o tratamento precoce com aspirina em mulheres de alto risco identificadas pela triagem pode reduzir significativamente os casos de pré-
O documento descreve o novo instrumento chemagic Prime, uma solução automatizada para extração de DNA e RNA de amostras humanas. Ele usa esferas magnéticas em vez de placas para separar ácidos nucleicos de forma mais pura e intacta, reduzindo o risco de contaminação. O instrumento fornece extração de alta qualidade de DNA e RNA de várias amostras, como sangue total e tecidos, para aplicações como NGS, genotipagem e PCR.
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This document provides key analytical applications to help laboratories address the pressing concerns of the changing global landscape. Specifically, Volume 10 includes applications for Energy & Industrial, Environmental, Food & Beverage, and Pharmaceuticals & Nutraceuticals.
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Spotlight on Applications is a quarterly compendium of recent applications, delivering a variety of topics that address the pressing issues and analytical challenges you may face today. Our e-zine covers a broad range of applications within various industries – all accessible online at your convenience.
PerkinElmer Application Note: Monitoring volatile organic compounds in beer p...PerkinElmer, Inc.
Beer is a popular beverage produced by the fermentation of hopped malt extracted from barley and other grains. Although simple in concept, beer is a highly complex mixture of many compounds including sugars, proteins, alcohols, esters, acids, ketones, acids and terpenes. Flavor is an important quality of any beer and the chemical content of the beer is obviously responsible for that flavor. Aroma is an extremely important part of the flavor and so there is a strong interest by brewers in the volatile organic compounds (VOCs) in beer that affect it's aroma. This application note describes a system comprising a headspace trap sampler to extract and concentrate VOCs from a beer sample and deliver them to a gas chromatograph/mass spectrometer (GC/MA) for separation, identification and quantification.
FTIR spectroscopy involves using infrared light to analyze materials. It works by passing infrared light through a sample and measuring the vibrations and rotations of molecules to determine chemical structure. Common applications of FTIR spectroscopy include identifying polymers, analyzing pharmaceuticals and contaminants, monitoring emissions, and performing quality control tests of materials.
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Spotlight on Applications is a quarterly compendium of recent applications, delivering a variety of topics that address the pressing issues and analytical challenges you may face today. Our e-zine covers a broad range of applications within various industries – all accessible online at your convenience.
http://www.perkinelmerapplications.com/subscribe/
Spotlight on Analytical Applications e-Zine - Volume 13PerkinElmer, Inc.
This document provides key analytical applications to help laboratories address the pressing concerns of the changing global landscape. Specifically, Volume 13 includes applications for Consumer Products, Energy & Industrial, Environmental and Pharmaceuticals & Nutraceuticals.
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Cardanol is a renewable organic resource obtained as a byproduct from the cashew industry. The present study has been carried out with an aim to manufacture rigid polyurethanes from natural and eco – friendly sources due to the rising prices of petrochemicals and also as an environmental concern. Vegetable oil based polyurethanes promising a new generation polymers which are low cost materials in the family of polyurethanes. Cardanol based phenolic resin has been synthesized by condensing cardanol with furfural in a particular mole ratio using phthalic acid as catalyst. The progress of the reaction was monitored by determining the free furfural and free phenol content. The resin was cured by using the curing agent 4, 41 - methylene bis(cyclohexyl isocyanate) and the catalyst dibutyltin dilaurate to produce polyurethane. Polyurethanes are an important class of polymers that have found place in many applications. The physico chemical and spectral properties of resin and polyurethane have also been studied.
The document describes the analysis of acetone, n-hexane, MIBK, MIBC, and MNBK from a soil decontamination process using an Agilent 490 Micro GC. Steam is injected into polluted soil to evaporate contaminants, and the steam with contaminants is analyzed by the Micro GC. The Micro GC uses two columns, a CP-Sil 5 CB column and a CP-Wax 52 CB column, to separate the compounds of interest in the ppm range in the presence of air and moisture. The Micro GC provides lab-quality analysis of gas mixtures in a compact, portable device.
Analysis of Arsenic, Cadmium and Lead in Chinese Spice Mixtures using Graphit...PerkinElmer, Inc.
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analyze the levels of toxic heavy metals like lead, cadmium
and arsenic that may be present in some major spice brands
available in the local markets in China, by using graphite
furnace atomic absorption spectrophotometry (GFAAS); (2)
to cross-reference these measured levels to the recommended limits specified by the U.S. FDA.
Learn more about our solutions: http://bit.ly/1iXLg0D
Physics Of A Magritek Nmr SpectrometerLaura Martin
The document discusses techniques used to identify an unknown compound, including NMR spectroscopy, IR spectroscopy, and mass spectrometry. NMR spectroscopy involves dissolving a sample in a deuterated solvent and obtaining a spectrum that shows proton or carbon chemical shifts. IR spectroscopy subjects molecules to infrared light which produces a spectrum indicating functional groups based on frequencies and transmittance. Mass spectrometry breaks molecules into ions and provides molecular mass information. These spectroscopy techniques are useful in pharmaceutical development for determining chemical and physical properties and identifying active ingredients.
This document provides an abstract for a report on ethylene production. It discusses commercial steam cracking technologies used to produce ethylene from naphtha, ethane/propane, including developing technologies like gas-to-ethylene. It examines the costs of producing ethylene from different feedstocks and regional supply and demand. The abstract outlines the major commercial technologies, developments in different regions, and provides an overview of the steam cracking process used for natural gas liquids and naphtha.
This document discusses elemental impurities in pharmaceuticals. It describes the method used to establish permitted daily exposures (PDEs) for elemental impurities, which involves deriving a PDE from toxicity studies in animals using modifying factors. It then lists the established PDEs for various elemental impurities according to their class. Finally, it discusses several instrumentation techniques for determining elemental impurities, including flame atomic absorption, electrothermal atomization, and hydride generation atomic absorption spectroscopy.
IOSRPHR(www.iosrphr.org) IOSR Journal of Pharmacyiosrphr_editor
This document summarizes a study analyzing the phytochemical constituents of Hybanthus enneaspermus using UV, FTIR, and GC-MS techniques. UV and FTIR analysis identified characteristic peaks indicating the presence of compounds like phenols, alcohols, acids, and aromatics. GC-MS identified 10 compounds in the ethanol extract including (5E,13E)-5,13-Docosadienoic acid and Cedran-diol, which have biological activities. The major findings provide insight into the bioactive compounds in H. enneaspermus with potential therapeutic applications.
IOSRPHR(www.iosrphr.org) IOSR Journal of Pharmacyiosrphr_editor
This document presents a study analyzing the phytochemical constituents of Hybanthus enneaspermus using UV, FTIR and GC-MS techniques. The UV and FTIR analysis identified various functional groups present in the plant's ethanol extract, including phenols, alcohols, alkanes and carboxylic acids. GC-MS analysis identified 10 compounds in the extract, with the major ones being (5E,13E)-5,13-Docosadienoic acid and Cedran-diol, which have antimicrobial and anti-inflammatory properties. The study characterized several bioactive compounds in H. enneaspermus with potential therapeutic applications.
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Collagen and bone fat are important resources in the food industry. It is essential that these primary products are odor- and taste free. Extensive de-odourization processes are used during bone fat & collagen processing to eliminate any off-flavors that might be present. Regular sensory evaluation performed by specially trained panels in combination with GC-MS analysis ensures product quality is not compromised.
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Toxic Trace Metals in Edible Oils by Graphite Furnace Atomic Absorption Spect...PerkinElmer, Inc.
"This method reports the development of a direct analysis
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volume, direct introduction of samples, high sensitivity, and
rapid analysis times. The application of GFAAS to arsenic,
lead and cadmium analysis in edible oils was performed.
The optimal pyrolysis and atomization temperatures, limit of detection, quality control (QC) checks and recoveries were studied in order to develop a rapid and accurate method.
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Application Note
Authors:
Lauren Amable
National Institute on Minority Health and
Health Disparities, National Institutes of Health
Bethesda, MD
Stan Smith
Chady Stephan
PerkinElmer, Inc.
Shelton, CT
O documento descreve o cromatógrafo gasoso PerkinElmer Clarus All-In-One, que possui um gerador de gases hidrogênio e ar sintético integrado, eliminando a necessidade de instalação de linhas de gases caras ou centrais de armazenamento de cilindros. O sistema possui manutenção simplificada, tela sensível ao toque, regeneração automática do secador a frio e modo stand-by automático controlado por sensor de hidrogênio.
High Quality DNA Isolation Suitable for Ultra Rapid SequencingPerkinElmer, Inc.
1) Modifications were made to decrease the time for whole genome sequencing (WGS) including faster DNA isolation, optimized sample preparation, sequencing and bioinformatics analysis.
2) DNA isolation using the chemagic MSM I instrument was optimized to isolate DNA from 24 blood samples in 1.5 hours, yielding 40 μg/mL of high quality DNA suitable for sequencing.
3) Sequencing on an Illumina HiSeq 2500 was modified for ultra rapid runs, taking approximately 20 hours to sequence a genome to 40x coverage while maintaining over 90% of bases above Q30. Alignment and variant detection using Isaac software took less than 3.5 hours.
GDG Cloud Southlake #33: Boule & Rebala: Effective AppSec in SDLC using Deplo...James Anderson
Effective Application Security in Software Delivery lifecycle using Deployment Firewall and DBOM
The modern software delivery process (or the CI/CD process) includes many tools, distributed teams, open-source code, and cloud platforms. Constant focus on speed to release software to market, along with the traditional slow and manual security checks has caused gaps in continuous security as an important piece in the software supply chain. Today organizations feel more susceptible to external and internal cyber threats due to the vast attack surface in their applications supply chain and the lack of end-to-end governance and risk management.
The software team must secure its software delivery process to avoid vulnerability and security breaches. This needs to be achieved with existing tool chains and without extensive rework of the delivery processes. This talk will present strategies and techniques for providing visibility into the true risk of the existing vulnerabilities, preventing the introduction of security issues in the software, resolving vulnerabilities in production environments quickly, and capturing the deployment bill of materials (DBOM).
Speakers:
Bob Boule
Robert Boule is a technology enthusiast with PASSION for technology and making things work along with a knack for helping others understand how things work. He comes with around 20 years of solution engineering experience in application security, software continuous delivery, and SaaS platforms. He is known for his dynamic presentations in CI/CD and application security integrated in software delivery lifecycle.
Gopinath Rebala
Gopinath Rebala is the CTO of OpsMx, where he has overall responsibility for the machine learning and data processing architectures for Secure Software Delivery. Gopi also has a strong connection with our customers, leading design and architecture for strategic implementations. Gopi is a frequent speaker and well-known leader in continuous delivery and integrating security into software delivery.
In his public lecture, Christian Timmerer provides insights into the fascinating history of video streaming, starting from its humble beginnings before YouTube to the groundbreaking technologies that now dominate platforms like Netflix and ORF ON. Timmerer also presents provocative contributions of his own that have significantly influenced the industry. He concludes by looking at future challenges and invites the audience to join in a discussion.
Pushing the limits of ePRTC: 100ns holdover for 100 daysAdtran
At WSTS 2024, Alon Stern explored the topic of parametric holdover and explained how recent research findings can be implemented in real-world PNT networks to achieve 100 nanoseconds of accuracy for up to 100 days.
UiPath Test Automation using UiPath Test Suite series, part 5DianaGray10
Welcome to UiPath Test Automation using UiPath Test Suite series part 5. In this session, we will cover CI/CD with devops.
Topics covered:
CI/CD with in UiPath
End-to-end overview of CI/CD pipeline with Azure devops
Speaker:
Lyndsey Byblow, Test Suite Sales Engineer @ UiPath, Inc.
How to Get CNIC Information System with Paksim Ga.pptxdanishmna97
Pakdata Cf is a groundbreaking system designed to streamline and facilitate access to CNIC information. This innovative platform leverages advanced technology to provide users with efficient and secure access to their CNIC details.
Generative AI Deep Dive: Advancing from Proof of Concept to ProductionAggregage
Join Maher Hanafi, VP of Engineering at Betterworks, in this new session where he'll share a practical framework to transform Gen AI prototypes into impactful products! He'll delve into the complexities of data collection and management, model selection and optimization, and ensuring security, scalability, and responsible use.
DevOps and Testing slides at DASA ConnectKari Kakkonen
My and Rik Marselis slides at 30.5.2024 DASA Connect conference. We discuss about what is testing, then what is agile testing and finally what is Testing in DevOps. Finally we had lovely workshop with the participants trying to find out different ways to think about quality and testing in different parts of the DevOps infinity loop.
Dr. Sean Tan, Head of Data Science, Changi Airport Group
Discover how Changi Airport Group (CAG) leverages graph technologies and generative AI to revolutionize their search capabilities. This session delves into the unique search needs of CAG’s diverse passengers and customers, showcasing how graph data structures enhance the accuracy and relevance of AI-generated search results, mitigating the risk of “hallucinations” and improving the overall customer journey.
Epistemic Interaction - tuning interfaces to provide information for AI supportAlan Dix
Paper presented at SYNERGY workshop at AVI 2024, Genoa, Italy. 3rd June 2024
https://alandix.com/academic/papers/synergy2024-epistemic/
As machine learning integrates deeper into human-computer interactions, the concept of epistemic interaction emerges, aiming to refine these interactions to enhance system adaptability. This approach encourages minor, intentional adjustments in user behaviour to enrich the data available for system learning. This paper introduces epistemic interaction within the context of human-system communication, illustrating how deliberate interaction design can improve system understanding and adaptation. Through concrete examples, we demonstrate the potential of epistemic interaction to significantly advance human-computer interaction by leveraging intuitive human communication strategies to inform system design and functionality, offering a novel pathway for enriching user-system engagements.
Full-RAG: A modern architecture for hyper-personalizationZilliz
Mike Del Balso, CEO & Co-Founder at Tecton, presents "Full RAG," a novel approach to AI recommendation systems, aiming to push beyond the limitations of traditional models through a deep integration of contextual insights and real-time data, leveraging the Retrieval-Augmented Generation architecture. This talk will outline Full RAG's potential to significantly enhance personalization, address engineering challenges such as data management and model training, and introduce data enrichment with reranking as a key solution. Attendees will gain crucial insights into the importance of hyperpersonalization in AI, the capabilities of Full RAG for advanced personalization, and strategies for managing complex data integrations for deploying cutting-edge AI solutions.
Removing Uninteresting Bytes in Software FuzzingAftab Hussain
Imagine a world where software fuzzing, the process of mutating bytes in test seeds to uncover hidden and erroneous program behaviors, becomes faster and more effective. A lot depends on the initial seeds, which can significantly dictate the trajectory of a fuzzing campaign, particularly in terms of how long it takes to uncover interesting behaviour in your code. We introduce DIAR, a technique designed to speedup fuzzing campaigns by pinpointing and eliminating those uninteresting bytes in the seeds. Picture this: instead of wasting valuable resources on meaningless mutations in large, bloated seeds, DIAR removes the unnecessary bytes, streamlining the entire process.
In this work, we equipped AFL, a popular fuzzer, with DIAR and examined two critical Linux libraries -- Libxml's xmllint, a tool for parsing xml documents, and Binutil's readelf, an essential debugging and security analysis command-line tool used to display detailed information about ELF (Executable and Linkable Format). Our preliminary results show that AFL+DIAR does not only discover new paths more quickly but also achieves higher coverage overall. This work thus showcases how starting with lean and optimized seeds can lead to faster, more comprehensive fuzzing campaigns -- and DIAR helps you find such seeds.
- These are slides of the talk given at IEEE International Conference on Software Testing Verification and Validation Workshop, ICSTW 2022.
LF Energy Webinar: Electrical Grid Modelling and Simulation Through PowSyBl -...DanBrown980551
Do you want to learn how to model and simulate an electrical network from scratch in under an hour?
Then welcome to this PowSyBl workshop, hosted by Rte, the French Transmission System Operator (TSO)!
During the webinar, you will discover the PowSyBl ecosystem as well as handle and study an electrical network through an interactive Python notebook.
PowSyBl is an open source project hosted by LF Energy, which offers a comprehensive set of features for electrical grid modelling and simulation. Among other advanced features, PowSyBl provides:
- A fully editable and extendable library for grid component modelling;
- Visualization tools to display your network;
- Grid simulation tools, such as power flows, security analyses (with or without remedial actions) and sensitivity analyses;
The framework is mostly written in Java, with a Python binding so that Python developers can access PowSyBl functionalities as well.
What you will learn during the webinar:
- For beginners: discover PowSyBl's functionalities through a quick general presentation and the notebook, without needing any expert coding skills;
- For advanced developers: master the skills to efficiently apply PowSyBl functionalities to your real-world scenarios.
Unlock the Future of Search with MongoDB Atlas_ Vector Search Unleashed.pdfMalak Abu Hammad
Discover how MongoDB Atlas and vector search technology can revolutionize your application's search capabilities. This comprehensive presentation covers:
* What is Vector Search?
* Importance and benefits of vector search
* Practical use cases across various industries
* Step-by-step implementation guide
* Live demos with code snippets
* Enhancing LLM capabilities with vector search
* Best practices and optimization strategies
Perfect for developers, AI enthusiasts, and tech leaders. Learn how to leverage MongoDB Atlas to deliver highly relevant, context-aware search results, transforming your data retrieval process. Stay ahead in tech innovation and maximize the potential of your applications.
#MongoDB #VectorSearch #AI #SemanticSearch #TechInnovation #DataScience #LLM #MachineLearning #SearchTechnology
Threats to mobile devices are more prevalent and increasing in scope and complexity. Users of mobile devices desire to take full advantage of the features
available on those devices, but many of the features provide convenience and capability but sacrifice security. This best practices guide outlines steps the users can take to better protect personal devices and information.
Goodbye Windows 11: Make Way for Nitrux Linux 3.5.0!SOFTTECHHUB
As the digital landscape continually evolves, operating systems play a critical role in shaping user experiences and productivity. The launch of Nitrux Linux 3.5.0 marks a significant milestone, offering a robust alternative to traditional systems such as Windows 11. This article delves into the essence of Nitrux Linux 3.5.0, exploring its unique features, advantages, and how it stands as a compelling choice for both casual users and tech enthusiasts.
Goodbye Windows 11: Make Way for Nitrux Linux 3.5.0!
Spotlight on Analytical Applications e-Zine - Volume 9
1. CONTENTS
TABLE OF
SPOTLIGHT
ON APPLICATIONS.
FOR A BETTER
TOMORROW.
VOLUME 9
2. CONTENTS
TABLE OF
INTRODUCTION
PerkinElmer Spotlight on Applications e-Zine – Volume 9
PerkinElmer knows that the right training, methods and application support are
as integral to getting answers as the instrumentation. That’s why PerkinElmer has
developed a novel approach to meet the challenges that today’s labs face, delivering
you complete solutions for your application challenges.
We are pleased to share with you our Spotlight on Applications e-zine, which
delivers a variety of topics that address the pressing issues and analytical challenges
you may face in your application areas today.
Our Spotlight on Applications e-zine consists of a broad range of applications
you’ll be able to access at your convenience. Each application in the table of
contents includes an embedded link which that take you directly to the appropriate
page within the e-zine.
We invite you to explore, enjoy and learn!
Be sure to receive future
issues by subscribing here.
PerkinElmer
3. CONTENTS
TABLE OF
CONTENTS
Energy & Industrial
• Analysis of Bioethanol Impurities with the Spectrum Two FT-IR Spectrometer
• nstrumental Requirements for Accurate Analysis of Optical Components: A comparison of the
I
PerkinElmer 983 Dispersive Spectrometer and the Frontier Optica FT-IR Spectrometer
• nalysis of Vanadium, Nickel, Sodium, and Iron in Fuel Oils using Flame Atomic Absorption
A
• etermination of Oil Content in Membranes Used in Compressed Air Sampling by
D
Infrared Spectroscopy
Environmental
• Organic Elemental Analysis of Soils — Understanding the Carbon-Nitrogen Ratio
• Determination of Hydrocarbons in Environmental Samples with Spectrum Two
Food Beverage
• Monitoring VOCs in Beer Production Using the Clarus SQ 8 GC/MS and TurboMatrix Headspace Trap
• ccurate Determination of Lead in Dairy Products by Graphite Furnace Atomic Absorption
A
• he Determination of Toxic, Trace, and Essential Elements in Food Matrices using THGA
T
Coupled with Longitudinal Zeeman Background Correction
• he Determination of Low Levels of Benzene, Toluene, Ethylbenzene, Xylenes and Styrene
T
in Olive Oil Using a TurboMatrix HS and a Clarus SQ 8 GC/MS
Forensics Toxicology
• enzoylecgonine in Urine by SAMHSA GC/MS
B
• ympathomimetic Amines in Urine by SAMHSA GC/MS
S
Pharmaceuticals Nutraceuticals
• yphenated DSC-Raman, a new Powerful Research Tool
H
• Study of Aged Carbon Nanotubes by Thermogravimetric Analysis
A
PerkinElmer
4. CONTENTS
TABLE OF
a p p l i c at i o n n o t E
FT-IR Spectroscopy
Authors
Ben Perston
Joe Baldwin
PerkinElmer, Inc.
Shelton, CT 06484 USA
Analysis of Bioethanol Introduction
The intensifying global emphasis on developing sustainable
Impurities with the fuel supplies has led to increasing use of fuels derived from
biological sources. The most important of these are biodiesel
Spectrum Two FT-IR (produced by transesterification of plant and animal oils and
fats) and bioethanol, which is produced by fermentation of
Spectrometer sugars, starches and, increasingly, cellulose from a range of
crops including corn, sugarcane, wheat and sugarbeet.
The fermentation produces a complex mixture of ethanol and
byproducts, from which the ethanol is isolated by distillation.
The performance of the ethanol as a fuel is dependent on its
purity, and international standards such as ASTM® D4806 and
EN 15376 limit the allowable concentrations of impurities in fuel
ethanol and specify the test methods to be used. At present,
the specified tests are time-consuming chromatographic and
titrimetric methods, so a rapid spectroscopic method such as
FT-IR could provide an attractive alternative.
Figure 1. The Spectrum Two FT-IR Spectrometer.
In this note we show that the Spectrum Two™ FT-IR spectrometer
(Figure 1) can be used to develop a quantitative method with
sufficient sensitivity to meet the required detection limits for
methanol, water, C3–C5 alcohols and gasoline denaturant, while
requiring less than two minutes of analysis time per sample.
Download Entire Application Note
5. CONTENTS
TABLE OF
a p p l i c at i o n n o t e
FT-IR Spectroscopy
Authors
Dean H. Brown
Richard Spragg
PerkinElmer, Inc.
Shelton, CT 06484 USA
Instrumental Requirements for
Accurate Analysis of Optical
Abstract
Components: A comparison of In the development of the Frontier™
the PerkinElmer 983 Dispersive Optica™, PerkinElmer has addressed the
well known sources of error in the
Spectrometer and the Frontier measurement of challenging optical
materials with standard FT-IR instruments.
Optica FT-IR Spectrometer The resulting improved performance over
the previous standard of the optical industry
is demonstrated by both the verification
carried out internally, and also by that
carried out by an external test laboratory.
Introduction
Measurements of optical components are some of the most challenging that can be made with an
IR spectrometer (Figure 1). Since optical sensing systems can contain over 100 components, individual
measurements require very high accuracy to minimize cumulative errors. The samples themselves
present particular problems. Optical filters may themselves have 40 to 70 coating layers on a substrate
with high refractive index. This affects the measurement by distorting the beam. They are often
highly reflective, maximizing the potential errors from unwanted reflections.
For years the PerkinElmer® 983 double-beam dispersive IR spectrometer has been the standard for
this industry. However dispersive instruments take longer to acquire a spectrum and do not benefit
from the other advantages of FT-IR.1
Download Entire Application Note
6. CONTENTS
TABLE OF
a p p l i c at i o n n o t e
Atomic Absorption
Author
Stan Smith
PerkinElmer, Inc.
Shelton, CT 06484 USA
Analysis of Vanadium, Introduction
Elemental analysis of fuel oil is an important
Nickel, Sodium, and Iron step in quantifying its quality. Combustion
of fuels containing metals can lead to the
in Fuel Oils using formation of low melting-point compounds
that are corrosive to metal parts. The pres-
Flame Atomic Absorption ence of certain metals, even at trace levels,
can deactivate or foul catalysts used during
Spectrophotometry the processing of the oil. ASTM® International
publishes numerous test methods for the
analysis of petroleum products, including
fuel oils. ASTM® D5863-00a (2005),
“Standard Test Methods for Determination of Nickel, Vanadium, Iron, and Sodium
in Crude Oils and Residual Fuels by Flame Atomic Absorption Spectrometry”, is
an industry-standard method for the analysis of fuel oils. Due to its multi-element
capabilities, inductively coupled plasma optical emission spectroscopy (ICP-OES)
may be the preferred technique for petroleum analyses requiring many elements,
however, flame atomic absorption spectrophotometry (FAAS) methods are still
quite effective and rapid for smaller numbers of elements such as those required
for fuel oil analyses. In addition, flame AA instrumentation is significantly more
compact than ICP-OES instruments, costs a fraction of the price, and requires less
operator training.
Download Entire Application Note
7. CONTENTS
TABLE OF
a p p l i c at i o n n o t e
FT-IR Spectroscopy
Author
Avdhut L. Maldikar, Ph.D.
Perkin Elmer, Pvt. Ltd.
Kasarvadavali, Thane (West)
India
Determination of Oil Introduction
Compressed air sampling is very essential
Content in Membranes from an environmental point of view,
wherein it is required to know all the
Used in Compressed Air environmental parameters such as SOx
and NOx. These parameters are very
Sampling by Infrared important to determine the air quality.
Membranes used in compressor should be
Spectroscopy oil free. Hence quantitative estimation of
oil trapped in the membranes being used
in air compressor is very important. FT-IR
studies can be very effective in calculating
the oil content in membranes to a very
low level as well. This type of work is being carried out using FT-IR in the envi-
ronmental segment using such tools as the Environmental Hydrocarbons FT-IR
Analysis System (http://www.perkinelmer.com/Catalog/Product/ID/L160000S),
which includes the Spectrum Two instrument and Spectrum Touch software with
an application for oil in water measurement.
This note describes the test method for the quantitative analysis of aerosol oil
and liquid oil typically present in the air discharged from compressors and com-
pressed air systems. The method is rapid, sensitive and cost effective and shows
the FT-IR can be an effective tool for the monitoring of oil content. The meth-
odology followed for the analysis by FT-IR is reported in BIS (Bureau of Indian
Standard)1 and we have also tested for its ruggedness, spike recovery, linearity
and detection limits.
Download Entire Application Note
8. CONTENTS
TABLE OF
a p p l i c at i o n n o t e
Elemental Analysis
Organic Elemental Introduction
Analysis of Soils – Understanding the health of the soil in which crops grow is
fundamental in ensuring healthy yields. Two elements that are
Understanding the essential to this are Carbon and Nitrogen, especially in their
proportion to each other. This relationship is called the Carbon-
Carbon-Nitrogen Ratio Nitrogen or CN ratio. This ratio is relatively simple to understand.
If soil is made up of 30% Carbon and 2% Nitrogen then the
CN ratio is 15 to 1. Carbon is important because of it’s energy
content in the form of species such as carbohydrates, whereas Nitrogen is essential for growth. Average
CN ratios vary from country to country depending on the predominant soil type, but a value between
8 and 17 is typical.1 Fertilizers, which are added to soils to regulate the CN ratio, should also be consid-
ered. When organic matter is added to soil the breakdown of the content by bacteria and fungi causes
changes in the CN ratio. It is important that any fertilizer added has sufficient nitrogen levels or the
addition will have a negative effect. The addition of composted manure, which typically has a CN ratio
of about 20:1, is desirable however the addition of sawdust, which has a high CN ratio of 400:1, could
be disastrous.2 The microorganisms that break down the organic matter will very quickly run out of Nitrogen
and therefore will start to consume the Nitrogen in the soil. This reduces the amount available to the
plants and therefore depresses crop yield. In addition to these, both Carbon and Nitrogen can be further
broken down into organic and inorganic subsections. Carbon in particular is often quoted as TOC, total
organic Carbon, and TIC, total inorganic Carbon. TOC takes into account all the Carbon from such
sources as decaying vegetation or bacterial growth. TIC includes all Carbon remaining so Carbon in
the form of carbonates and bicarbonates, for example.
Download Entire Application Note
9. CONTENTS
TABLE OF
a p p l i c at i o n n o t E
FT-IR Spectroscopy
Authors
Ben Perston
Aniruddha Pisal
PerkinElmer, Inc.
Shelton, CT 06484 USA
Determination of Introduction
The concentration of dispersed oil and grease in water is an important
Hydrocarbons in parameter for human and environmental health. Infrared spectroscopy has
long been a standard method for detecting and quantifying hydrocarbon
Environmental contamination, particularly in water discharged during offshore oil operations.1
Samples with Recently, this analytical technique has enjoyed renewed interest and
application to a wider range of environmental samples and matrices, from
Spectrum Two cooling water, to soil in land reclamation, to drinking water; at the same
time, concern over the environmental impact of chlorofluorocarbon
solvents has led to the development of a number of alternative approaches
using less harmful solvents. This application note presents an overview of
three methods and a comparison of their performance:
1. Halogenated solvent extraction and transmission measurement (C–H
stretch modes), e.g. ASTM® D7066. This is the traditional approach, but
requires the use of relatively expensive solvents that may be harmful.
2. Hexane extraction and ATR measurement allows the use of an inexpensive
hydrocarbon solvent, but does not permit the measurement of volatile
contaminants.
3. Cyclohexane extraction and transmission measurement (1377 cm-1)
exploits a deformation mode that is not present in the spectra of
cycloalkanes (see Figure 1), and combines the simplicity of a transmission
measurement with a hydrocarbon solvent.2
All three of these methods are supported by the Spectrum Two
Environmental Hydrocarbons Analysis System (Figure 2), with the
appropriate sampling accessory. This note evaluates the three methods
and discusses their relative advantages.
Download Entire Application Note
10. CONTENTS
TABLE OF
a p p l i c at i o n n o t e
Gas Chromatography/
Mass Spectrometry
Authors
Lee Marotta
Sr. Field Application Scientist
Andrew Tipler
Senior Scientist
PerkinElmer, Inc.
Shelton, CT 06484 USA
Monitoring Volatile Introduction
Beer is a popular beverage produced by the fermentation
Organic Compounds of hopped malt extracted from barley and other
grains. Although simple in concept, beer is a highly
in Beer Production Using complex mixture of many compounds including
the Clarus SQ 8 GC/MS sugars, proteins, alcohols, esters, acids, ketones, acids
and terpenes. Flavor is an important quality of any
and TurboMatrix Headspace beer and the chemical content of the beer is obviously
responsible for that flavor. Aroma is an extremely
Trap Systems important part of the flavor and so there is a strong
interest by brewers in the volatile organic compounds
(VOCs) in beer that affect its aroma.
Some VOCs have a positive effect on aroma (attributes) and some have a negative
effect (defects). The ability to characterize these in beer products before, during and
after fermentation would be an important tool in process control, quality assurance
and product development.
This application note describes a system comprising a headspace trap sampler to extract
and concentrate VOCs from a beer sample and deliver them to a gas chromatograph/
mass spectrometer (GC/MS) for separation, identification and quantification.
The purpose of our experiments is to demonstrate that attributes and defects can all be
monitored using one detector and from a single injection with mass spectrometry (MS).
The associated benefits include a quicker return on investment, enhanced productivity,
more information from a single analysis, and less bench space requirements.
Download Entire Application Note
11. CONTENTS
TABLE OF
a p p l i c at i o n n o t e
Atomic Absorption
Authors
Jijun Yao
Renkang Yang
Jianmin Chen
PerkinElmer, Inc.
Shelton, CT 06484 USA
Accurate Determination Introduction
Milk is one of the basic food groups in the human
of Lead in Different diet, both in its original form and as various dairy
products. The Chinese contaminated baby formula
Dairy Products by scandal in 2008 has increased public awareness of
contamination possibilities, and has lead to tighter
Graphite Furnace Atomic supervision of dairy products as China is faced with
demands – both from home and abroad – to improve
Absorption Spectrometry its food safety record. It is well-known that lead (Pb)
is toxic and causes damage to the nervous system; it
has a particularly detrimental effect on young chil-
dren1 and it has become a cause of major concern since the 1970s. As per World Health
Organization (WHO) standards, the permissible limit of lead in drinking water is 10 µg/kg
(parts per billion, ppb). Following an in-depth review of the toxicological literature, the
Chinese guideline for maximum levels of lead content is set at 20 µg/kg (ppb wet weight) in
infant formula (use of milk as a raw material measured by fluid milk diluted from powder,
referring to the product ready-to-use) and at 50 µg/kg (ppb) in fresh milk, respectively.2
Lead analysis has traditionally been one of the major applications of graphite furnace atomic
absorption spectrometry (GFAAS) worldwide. Currently, the Chinese regulatory framework
approved standard methods for lead analysis has set GFAAS as the technique for the
compulsory arbitration in food testing.3 In order to ensure protection of consumers, analysis
should be sensitive, efficient, and cost-effective so that more effective monitoring can be
accomplished. Because GFAAS is a mature technique, it is well-understood and routinely
used by technicians and suitable for this determination. Sample preparation is an important
part of an analysis and yet can be time consuming.
Download Entire Application Note
12. CONTENTS
TABLE OF
a p p l i c at i o n n o t e
Atomic Absorption
Authors
David Bass
Senior Product Specialist
Cynthia P. Bosnak
Senior Product Specialist
PerkinElmer, Inc.
Shelton, CT 06484 USA
The Determination of Toxic, Introduction
Ingestion of trace elements from food
Trace, and Essential Elements in can be linked to nutrition, disease, and
physiological development. Whether they
Food Matrices using THGA are needed for proper nutritional value or
contain toxic elements, the presence of
Coupled with Longitudinal major and minor elements in food needs
to be verified to help determine health
Zeeman Background Correction effects for the consumer. Contamination
of food products may result from metals
present during cultivation and/or processing.
Acute or chronic exposure to heavy metals
can lead to damaged nervous system function and have detrimental effects on vital
organs. Food safety laboratories performing these analyses are often high-throughput
facilities and require a detection tool that is efficient and cost effective.
Unlike flame atomic absorption spectrophotometry (FAAS) where the ground
state atoms quickly diffuse into surrounding air, graphite furnace atomic absorption
spectrophotometry (GFAAS), being a total consumption technique, offers the
ability to dry and atomize the entire pipetted sample in a more controlled
environment within the graphite tube. This significantly increases sensitivity and
provides superior detection limits with microliter (μL) sample volumes. Only
ICP-MS can provide the same level of detection as GFAAS, however GFAAS is more
cost efficient, simpler to operate and has fewer laboratory facility requirements.
Download Entire Application Note
13. CONTENTS
TABLE OF
a p p l i c at i o n n o t e
Gas Chromatography/
Mass Spectrometry
Author
A. Tipler, Senior Scientist
PerkinElmer, Inc.
Shelton, CT 06484 USA
The Determination of Low Levels of Benzene,
Toluene, Ethylbenzene, Xylenes and Styrene in
Olive Oil Using a TurboMatrix HS and a Clarus
SQ 8 GC/MS
Introduction
Levels of benzene, toluene, ethylbenzene, xylenes and styrene (BTEXS) are a concern in olive
oil. These compounds find their way into olive trees and hence into the olives and olive oil
mainly as a result of emissions from vehicles, bonfires, and paints into ambient air near the
orchards.
Various methods have been developed to detect and quantify these compounds down to
levels of 5 ng/g (5 ppb w/w). This application note describes an easy to perform method
using PerkinElmer® Clarus® SQ 8 GC/MS with a TurboMatrix™ 110 headspace sampler to
achieve detection limits below 0.5 ng/g.
Download Entire Application Note
14. CONTENTS
TABLE OF
a p p l i c at i o n n o t e
Gas Chromatography/
Mass Spectrometry
Author
Timothy D. Ruppel
PerkinElmer, Inc.
Shelton, CT 06484 USA
Benzoylecgonine in Introduction
The United States Department of Health
Urine by SAMHSA and Human Services (DHHS), Substance
Abuse and Mental Health Services
GC/MS Administration (SAMHSA) regulates urine
drug testing programs in the Mandatory
Guidelines for the Federal Workplace
Drug Testing Program. These Mandatory
Guidelines require a laboratory to
conduct two analytical tests before a urine specimen can be reported positive
for a drug, the initial drug test and the confirmatory drug test. The initial drug
test is performed by immunoassay screening for the five drug classes (i.e.,
amphetamines, cocaine, opiates, phencyclidine and marijuana). Examples
of immunoassay screening would include radioimmunoassay (RIA), enzyme
immunoassay (EIA, EMIT) or others.
Samples found positive to the immunoassay screening are subjected to a
second confirmatory test by chromatographic separation and identification
by mass spectrometry. SAMHSA defines the Method Quantification Cutoff
Level as 100 ng/mL for benzoylecgonine, the major metabolite of cocaine.
Download Entire Application Note
15. CONTENTS
TABLE OF
a p p l i c at i o n n o t e
Gas Chromatography/
Mass Spectrometry
Author
Timothy D. Ruppel
PerkinElmer, Inc.
Shelton, CT 06484 USA
Sympathomimetic Introduction
The United States Department of Health
Amines in Urine by and Human Services (DHHS), Substance
Abuse and Mental Health Services
SAMHSA GC/MS Administration (SAMHSA) regulates urine
drug testing programs in the Mandatory
Guidelines for the Federal Workplace
Drug Testing Program. These Mandatory
Guidelines require a laboratory to conduct
two analytical tests before a urine specimen can be reported positive for a drug,
the initial drug test and the confirmatory drug test. The initial drug test is
performed by immunoassay screening for the five drug classes (i.e., amphetamines,
cocaine, opiates, phencyclidine, and marijuana). Examples of immunoassay
screening would include radioimmunoassay (RIA), enzyme immunoassay (EIA,
EMIT) or others.
Samples found positive to the immunoassay screening are subjected to a
second confirmatory test by chromatographic separation and identification by
mass spectrometry. SAMHSA defines the Method Quantification Cutoff Level
as 250 ng/mL for each of 5 amines (AMP, MAMP, MDA, MDMA, MDEA).
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16. CONTENTS
TABLE OF
Case
Pharmaceutical
study
Hyphenated “The DSC-Raman offers the advantage of collecting important
DSC-Raman, data with one simple experiment which is not possible with any
other instrument. It’s a powerful and exciting tool for material
a new Powerful characterization in the early stage of drug development and can
take us to the next level of analysis. It also has the potential to
Research Tool. provide in-depth understanding of pharmaceutical systems.”
– Research Investigator
(a major U.S. pharmaceutical company)
Differential Scanning Calorimetry (DSC) and Raman spectroscopy are comple-
mentary analytical techniques. DSC measures thermal behaviors of samples like
glass transition temperature (Tg), melting temperature and melting enthalphy,
crystallization. While Raman gives insight into the chemical/physical structure of
the sample, they are often used to address the same material characterization
problem. Simultaneous DSC and Raman measurement offers more information
about the material which may be missed by each technique separately. Spectra
recorded continuously during the temperature scan can generate curves repre-
senting the changes in the Raman spectra for direct comparison with the DSC
heat flow curve.
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17. CONTENTS
TABLE OF
a p p l i c at i o n n o t e
Thermogravimetric Analysis
Authors
E. Sahle-Demessie
A. Zhao
U.S. EPA, Office of Research and Development
National Risk Management Research Laboratory
Cincinnati, OH 45268
A. W. Salamon
PerkinElmer, Inc.
Shelton, CT 06484 USA
A Study of Aged
Carbon Nanotubes by Introduction
Thermogravimetric Increased use of carbon nanotubes in consumer and industrial
products have scientists asking about the implications of CNTs in
Analysis our environment. Many end product applications include polymer
composites, drug delivery systems, coatings and films, military
applications, electronics, cosmetics, healthcare, among others.
CNTs are desirable for many applications because of their high surface area to weight
ratio. They are lightweight and highly elastic compared to carbon fibers, and deliver
higher surface area for increased chemical interaction in its specific application.
Thermogravimetry a simple analytical technique that is frequently used to characterize
carbon nanotubes.1 The Pyris™ 1 TGA delivers accurate results quickly because of its low
mass furnace. The Pyris 1 TGA low mass furnace has accurate temperature control and
fast cooling for higher sample throughput.
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