A presentation on inter-relationship between periodontal and orthodontic events. Helpful for dental graduates and perio and ortho post graduate students.
Orthodontic-periodontic interactions are mutually beneficial. Orthodontic treatment can be justified as a part of periodontal therapy if it is used to reduce plaque accumulation, correct abnormal gingival and osseous forms, improve aesthetics, and facilitate prosthetic replacement.
There are many benefits to integrating orthodontics and periodontics in the management of adult patients with underlying periodontal defects. The key to treating these patients is communication and proper diagnosis before orthodontic therapy. Not all periodontal problems are treated in the same way. It should be remembered that overall success of orthodontic treatment depends on the combined effort and close monitoring of the case, by an orthodontist and a periodontist.
Traumatic Occlusion and Pathologic tooth migrationAyam Chhatkuli
description about traumatic occlusion and pathologic tooth migrations.its pathogenesis, changes in the forces exerted on tooth, its treatment and prevention.
Orthodontic-periodontic interactions are mutually beneficial. Orthodontic treatment can be justified as a part of periodontal therapy if it is used to reduce plaque accumulation, correct abnormal gingival and osseous forms, improve aesthetics, and facilitate prosthetic replacement.
There are many benefits to integrating orthodontics and periodontics in the management of adult patients with underlying periodontal defects. The key to treating these patients is communication and proper diagnosis before orthodontic therapy. Not all periodontal problems are treated in the same way. It should be remembered that overall success of orthodontic treatment depends on the combined effort and close monitoring of the case, by an orthodontist and a periodontist.
Traumatic Occlusion and Pathologic tooth migrationAyam Chhatkuli
description about traumatic occlusion and pathologic tooth migrations.its pathogenesis, changes in the forces exerted on tooth, its treatment and prevention.
Orthodontics-Periodontics Relationship
ntroduction
Biological basis for orthodontic therapy
Periodontal tissue response to orthodontic force
Effects of orthodontic tooth movement on the periodontium
Orthodontic tooth movement in adults with periodontal tissue breakdown
Specific factors associated with orthodontic tooth movement
Implants and orthodontic therapy
Systematics of combined ortho – perio treatment
Periodontally Accelerated Osteogenic Orthodontics (PAOO)
Minor periodontal surgery and orthodontic treatment
Review of literature
Support in complete denture /orthodontic courses by Indian dental academy Indian dental academy
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
www.indiandentalacademy.com
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
www.indiandentalacademy.com
Physiology of tooth movement 1 /certified fixed orthodontic courses by Indian...Indian dental academy
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and offering a wide range of dental certified courses in different formats.
Indian dental academy provides dental crown & Bridge,rotary endodontics,fixed orthodontics,
Dental implants courses.for details pls visit www.indiandentalacademy.com ,or call
0091-9248678078
Presentation describing important values to be understood in periodontology. Helpful for dental graduate students and periodontology post graduate students and also for neet mds exams.
Orthodontics-Periodontics Relationship
ntroduction
Biological basis for orthodontic therapy
Periodontal tissue response to orthodontic force
Effects of orthodontic tooth movement on the periodontium
Orthodontic tooth movement in adults with periodontal tissue breakdown
Specific factors associated with orthodontic tooth movement
Implants and orthodontic therapy
Systematics of combined ortho – perio treatment
Periodontally Accelerated Osteogenic Orthodontics (PAOO)
Minor periodontal surgery and orthodontic treatment
Review of literature
Support in complete denture /orthodontic courses by Indian dental academy Indian dental academy
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
www.indiandentalacademy.com
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
www.indiandentalacademy.com
Physiology of tooth movement 1 /certified fixed orthodontic courses by Indian...Indian dental academy
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and offering a wide range of dental certified courses in different formats.
Indian dental academy provides dental crown & Bridge,rotary endodontics,fixed orthodontics,
Dental implants courses.for details pls visit www.indiandentalacademy.com ,or call
0091-9248678078
Presentation describing important values to be understood in periodontology. Helpful for dental graduate students and periodontology post graduate students and also for neet mds exams.
A presentation describing relationship between peridontics and prosthodontics and their implications. Helpful for dental graduates and perio and prostho post graduate students.
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
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Explore natural remedies for syphilis treatment in Singapore. Discover alternative therapies, herbal remedies, and lifestyle changes that may complement conventional treatments. Learn about holistic approaches to managing syphilis symptoms and supporting overall health.
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
Knee anatomy and clinical tests 2024.pdfvimalpl1234
This includes all relevant anatomy and clinical tests compiled from standard textbooks, Campbell,netter etc..It is comprehensive and best suited for orthopaedicians and orthopaedic residents.
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
- ARTIFICIAL INTELLIGENCE AND ETHICS
- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
2. INTRODUCTION
• The interrelationship between orthodontics and periodontics often
resembles symbiosis.
• In many cases, periodontal health is improved by orthodontic tooth
movement, whereas orthodontic tooth movement is often facilitated
by periodontal therapy.
• The orthodontic treatment is a double-action procedure, regarding
the periodontal tissues.
• So it is of utmost importance to assess the need and outcome of
interdisciplinary approach in different physiological, pathological or
deliberate alterations in tooth positions to maintain harmonious
periodontal and orthodontic relation.
3. PERIODONTAL AND BONE RESPONSE TO
NORMAL FUNCTION & FORCES
• During masticatory function, the teeth and periodontal structures are
subjected to intermittent heavy forces.
• Tooth contacts last for 1 second or less; forces are quite heavy,
ranging from 1 or 2 kg while soft substances are chewed up to as
much as 50 kg against a more resistant object.
• When a tooth is subjected to heavy loads of this type, quick
displacement of the tooth within the PDL space is prevented by the
incompressible tissue fluid.
• The force is transmitted to the alveolar bone, which bends in
response .
4. Physiologic Response to light Sustained
Pressure Against the Tooth
• Light pressure Events
< 1 sec PDL fluid incompressible, alveolar bone bends, piezoelectric signal generated
1-2 sec PDL fluid expressed, tooth moves within PDL space
3-5 sec Blood vessels within PDL partially compressed on pressure side, dilated on
tension side, PDL fibers mechanically distorted
Minutes Blood flow altered, Oxygen tension altered, release of prostaglandins and cytokines
Hours Metabolic changes occur, chemical messengers affect cellular activity
4 hours Detectable increase in CAMP level, cellular differentiation begins in PDL
2 days Tooth movement begins as osteoblasts and osteoclasts remodel bone
5. Physiologic response to heavy Sustained
Pressure against a tooth
• Heavy pressure Events
3-5 sec Blood vessels within PDL occlude on pressure side
Minutes Blood flow cutoff to compressed PDL area
Hours Cell death in compressed area
1-5 Days Cellular differentiation in adjacent marrow spaces, undermining
resorption begins
7-14 Days Undermining resorption removes lamina dura adjacent to compressed
PDL, tooth movement occurs
6. Periodontal tissue response to orthodontic
therapy
• Type of Force Tissue Response
Light Forces Ischemic PDL with continuous bone remodeling leading
to tooth movement
Moderate Forces PDL strangulation caused by delay in bone resorption
Heavy Forces PDL on the pressure side is crushed leading to local
degeneration and ischemia leading to hyalinization and
delay in tooth movement
7. Cascade of Events that Follow after Application of
Orthodontic Force: The Role of Inflammation in
Orthodontic Tissue Remodeling
8. As we apply orthodontic force on the tooth, various events at the
microscopic level occur . The sequence of events after the application
of mechanical forces with the help of orthodontic appliances can thus
be outlined as:
• Movement of PDL fluids from areas of compression into areas of
tension.
• A gradual development of strain in cells and ECM in the paradental
tissues involved.
• Release of phospholipase A2 and cleavage of phospholipids leading to
release of PGE2 and leukotrienes.
• ECM remodeling and signal transduction through integrin
transmembrane channels.
9. • Cytoplasmic alterations and release of 2nd messengers of tooth
movement—cAMP and cGMP, ionositol phosphates, and calcium and
tyrosine kinases.
• Release of kinases, such as protein kinase A, kinase C, and Mitigen-
activated protein MAP kinases.
• Direct transduction of mechanical forces to the nucleus of strained
cells through the cytoskeleton, leading to activation of specific genes.
• Release of neuropeptides (nociceptive and vasoactive) from
paradental afferent nerve endings.
• Interaction of vasoactive neuropeptides with endothelial cells in
strained paradental tissue.
10. • Adhesion of circulated leukocytes to activated endothelial cells.
• Migration by diapedesis of leukocytes into the extravascular space.
• Synthesis and release of signaling molecules by leukocytes that have
migrated into the strained paradental tissues.
• Interaction of various types of paradental cells with the signal
molecules released by the migratory leukocytes.
• Activation of the cells to participate in the modeling and remodeling
of the paradental tissues.
11. Role of Prostaglandins in Mediating OrthodonticTooth
Movement
• Classically, prostaglandins as one of the chief mediators of inflammation cause
an increase in intracellular cAMP and calcium accumulation by monocytic cells,
which then modulates and activates osteoclastic activity.
Cytokines and Growth Factors in OrthodonticTooth
Movement
• Cytokines secreted by leukocytes may interact directly with bone cells or
indirectly, via neighboring cells, such as monocytes/macrophages, lymphocytes,
and fibroblasts.
• Cytokines released have multiple activities, which include bone remodeling,
bone resorption, and new bone deposition.
12. RANK-RANKL-OPG
• The receptor activator of nuclear factor kappa B ligand (RANKL), its
decoy receptor (RANK), and OPG were found to play important roles
in regulation of bone metabolism.
• Evidences suggest osteoblast itself regulates the differentiation of
osteoclast.
• The talk between an osteoblast and an osteoclast is accomplished
through an osteoblast membrane bond RANKL, which can interact
with osteoclast precursors to cause them to differentiate into
osteoclasts.
13. Detection of Mechanical Strain by Bone Cells
• Researches indicate that the cells responsible for sensing mechanical
strains by orthodontic tooth movement involving application of
forces and movements from wires through brackets to teeth in the
bone are osteoblasts, or osteocytes, or both.
• Three theories have been suggested on how these cells sense
mechanical strain and how then the stimuli are passed into the cell
and from one cell to another.
• Strain-released potentials
• Activation of ion channels
• Extracellular matrix and cytoskeleton reorganization.
14. BENEFITS OF ORTHODONTIC TREATMENT
FOR A PERIODONTAL PATIENT
• Orthodontic therapy can provide several benefits to the adult patient with
periodontal problems.The following six factors should be considered:
1. Aligning crowded or malposed maxillary or mandibular anterior teeth permit the
adult patient better access to adequately clean all surfaces of their teeth.
2. Vertical orthodontic tooth repositioning can improve certain types of osseous
defects in periodontal patients. Often, the tooth movement eliminates the need
for resective osseous surgery.
3. Orthodontic treatment can improve the esthetic relationship of the maxillary
gingival margin levels before restorative dentistry. Aligning the gingival margins
orthodontically avoids gingival recontouring, which potentially could require bone
removal and exposure of the roots of the teeth.
15. 4. A patient who has suffered a severe fracture of a maxillary anterior tooth requires
forced eruption to permit adequate restoration of the root. In this situation, extruding
the tooth allows the crown preparation to have sufficient resistance form and
retention for the final restoration.
5. Orthodontic treatment allows open gingival embrasures to be corrected to regain lost
papilla. If these open gingival embrasures are located in the maxillary anterior region,
they can be unaesthetic.
6. Orthodontic treatment could improve adjacent tooth position before implant
placement or tooth replacement. This is especially true for the patients having missing
teeth for several years and drifted adjacent teeth in the edentulous space
16. ADVERSE EFFECTS OF ORTHODONTIC
PROCEDURES
• Decalcification, which leads to white spots and eventually caries
• Gingivitis
• Periodontitis
• Gingival recession
• Root resorption
• Formation of pockets (gingival/periodontal)
• Gingival Invaginations
• They are defined as superficial changes in the shape of gingiva, which arise after
moving the teeth orthodontically in order to close the spaces resulted from extraction.
17. Microbiology around orthodontic bands
• It has been also shown that different species of bacteria, such as
• Bacteroides intermedius
• Spirochetes
• B. forsythus
• T. dentcola
• P. nigrescens
• C. rectus
• Fusiform bacteria
were considered to increase more frequently in the dental plaque of patients
undergoing orthodontic treatment.
18. MINOR PERIODONTAL SURGERY ASSOCIATED
WITH ORTHODONTIC THERAPY
• Supracrestal fiberotomy
• It is a surgical technique that divides the free gingival
and transseptal fibers around rotated teeth that have
been corrected orthodontically for reducing
rotational relapse of orthodontically aligned teeth.
• The procedure involves moving around the
circumference of each of these teeth, gently
detaching the gingival fibers.
19. Frenectomy & Frenotomy
• The contribution of the maxillary labial frenum to the etiology of a persisting
midline diastema and to reopening of diastemas after orthodontic closure is often
encountered. Very hyperplastic types of frenum, with a fan-like attachment, may
obstruct diastema closure and should be relocated.
• Frenectomy is the complete removal of the frenum, including its attachment to the
underlying bone, while frenotomy is the incision and the relocation of the frenal
attachment
20. • Removal of Gingival Invaginations
(Clefts)
• Incomplete adaptation of supporting structures during
orthodontic closure of extraction spaces in adults may
result in folding or invagination of the gingiva.
• The clinical appearance of such invaginations may
range from a minor one-surface crease to deep clefts
that extend across the interdental papilla from the
buccal to the lingual gingivae.
• It has been suggested that simple removal of only the
excess gingiva in the buccal and lingual area of
approximated teeth would be sufficient to alleviate the
tendency for the teeth to separate after orthodontic
movement.
21. • Gingivectomy
• It is a procedure wherein there is excision of
gingiva by removing excess gingival overgrowth
thereby exposing tooth surface which provides
visibility and accessibility for complete calculus
removal .
• Orthodontic brackets and elastics might
interfere with effective removal of dental
plaque, thereby increasing the risk of gingivitis.
• In the majority of the patients, following
placement of a fixed appliance, small amount
gingival inflammation is visible which in absence
of proper oral hygiene may aggravate indicating
the need for gingivectomy.
22. • Surgical Exposure of UneruptedTooth
• Excision of gingival tissue over the embedded tooth
used to be a popular approach to achieve crown
exposure.
• However, the result is usually accomplished at the
expense of the keratinized tissue covering the
unerupted teeth.
• In order to avoid this problem, an improved
technique for the preservation of existing
keratinized tissue was developed, which involves the
repositioning of existing keratinized tissue.
23. • Mucogingival Surgery
• The lack of keratinized gingiva is one of the most
common complications following orthodontic
movement.
• Pre orthodontic mucogingival surgery is
indicated for teeth with an inadequate zone of
keratinized gingiva, to prevent mucogingival
involvement post-orthodontically, which is more
difficult to treat.
24. Orthodontic Treatment of Gingival
Discrepancies
• Uneven Gingival Margins
• These discrepancies could be caused by abrasion of the
incisal edges or delayed migration of the gingival
margins, when gingival margin discrepancies are
present, the proper solution for the problem must be
determined: Orthodontic tooth movement to reposition
the gingival margins or surgical correction of gingival
margin discrepancies.
25.
26. • Open Gingival Embrasures
• The presence of a papilla between the maxillary central incisors is a key esthetic factor in any
individual.
• This open space is usually due to one of three causes:Tooth shape, root angulation, or
periodontal bone loss.
• If a patient has an open embrasure, the first aspect that must be evaluated is whether the
problem is due to the papilla or the tooth contact.
• If the papilla is the problem, then the cause is usually a lack of bone support due to an
underlying periodontal problem.
• In some situations, a deficient papilla can be improved with orthodontic treatment.
• By closing open contacts, the interproximal gingiva can be squeezed and moved incisally.
27. Periodontally accelerated osteogenic
orthodontics (PAAO)
WilliamWilcko
Thomas Wilcko
The AOO procedure was developed by Drs.Thomas
and WilliamWilcko in 1995.Thomas Wilcko is a
Periodontist and his brother,WilliamWilcko, is an
Orthodontist.
30. CONCLUSION
• Patient education, motivation, enhanced oral hygiene maintenance and
regular periodontal care are essential during orthodontic treatment.
• Certain adjunctive periodontal procedures may help an orthodontist achieve
more stable and esthetically acceptable results.
• Orthodontics can serve as an adjunct to periodontal treatment procedures to
improve oral health in a number of situations.
• Close co-operation between the periodontist and orthodontist can ensure
excellent results with long-term stability.