This document discusses Amanda Fox's risk factors for heart disease. It notes that 25% of deaths in the US are due to heart disease, which can be caused by atherosclerosis and plaque buildup in the arteries. Amanda has several risk factors including high blood sugar, high blood pressure, high cholesterol, being overweight, low exercise levels, family history of heart disease and diabetes, and sickle cell disease. She is at moderate risk of heart attack. The document recommends that Amanda work with a cardiologist, nutritionist, and personal trainer to manage her risk factors through medication, diet changes, exercise, and lifestyle modifications.