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NURTURE NEGLECT
Dara Ajay PhD, LLM
Cheers Interactive.
II-PIC: International Indian Patent Information Conference for Patent Information Professionals
Disclaimer: The views and opinions expressed in this presentation are those
of the authors and do not necessarily reflect the official policy or position of
any governing body including Cheers Interactive.
❖Some of the related articles and
sections from Patent Act and TRIPS
India under Section 3
USA under Section 101 of Title 35 U.S.C.
Australia under section 18
Malaysia under Section 13
China Article 25
European Patent Convention Article 52, 53
TRIPS Article 27.2
2
➢what are not patentable
• Frivolous/ obvious inventions
• Contrary to well established natural laws
• Contrary to public order or morality
• Mere discovery of a scientific principle
• Formulation of an abstract theory
• Discovery of any living thing or non–living substance
occurring in nature
• Process for medicinal, surgical, curative,
prophylactic, diagnostic, therapeutic or other
treatment
• Method of agriculture or horticulture
• Plants & animals in whole or any part thereof
• Method of performing mental act or method of
playing game
• Mathematical method or business method or
algorithms or computer programme per se
http://www.ipindia.nic.in/writereaddata/Portal/IPOAct/1_31_1_patent-act-1970-11march2015.pdf
3
▪ The landmark case for Gene patenting is the Myriad Genetics, Inc.,
▪ Developed a diagnostic kit which detect gene sequence BRCA1 and BRCA2 genes
▪ Unfortunately, Myriads high price (USD $3000-4000)
https://en.wikipedia.org/wiki/BRCA_mutation
4
13th June 2013, US5747282, US5837492, US5693473,
US5709999, US5710001, US5753441 and US6033857
Invalidate the claims of isolated gene under 35 U.S.C. §101
5 September 2014, AU686004 based on manner of
manufacture indicating DNA and RNA as natural
products and invention as artificial state of affairs
November 2008 EP0705902, EP0705903, EP0699754,
EP0785216 “natural law or natural product but
ultimately whether it is for a mere discovery”
5
1. In Myriad case plaintiff failed to identify the anticompetitive practices
2. Weather gene isolation is mere discovery or invention ?
BRCA1-17q21
BRCA2- 13q12.3
http://www.scinexx.de/dossier-bild-15-6-21210.html
6
CANCER
The Cancer Statistics
✓~1.6 million new cases got registered with 35% dead rate
✓~ 14.1 million new cases reported with 8.2 million deaths
✓2020 prediction ~ 15 million new cases diagnosed, 12 million deaths
✓GLOBOCAN, 2025 estimation >19.3 million new cancer cases every year
7
https://www.myriadpro.com/ovarian-cancer-testing/bracanalysis-cdx-overview/
8
https://www.myriadpro.com/ovarian-cancer-testing/bracanalysis-cdx-overview/
Feng Zhang
@
Broad/MIT
Jennifer
Doudna @
Berkeley
/HHMI
CRISPR/
Cas9
Emmanuelle
Charpentie
@
Helmholtz
MIMS/MHH
9http://www.brandeis.edu/now/2014/october/gabbay-award-2104.html
http://blogs.plos.org/synbio/2017/10/05/when-will-crispr-get-a-nobel-prize/
“The discovery’s impact on medicine could be
huge. Imagine being able to delete BRCA 1,
the closely linked to breast cancer, or the that
causes Huntington’s disease. The
CRISPR/cas9 system puts scientists one step
closer to being able to cure genetic disorders”
CRISPRs, first observed in the 1980s
2014 Breakthrough Prize in Life Sciences ($3 million)
2015 Massry Prize ( $40,000)
2016 Canada Gairdner International Award ($100,000)
2016 Tang Prize in Biopharmaceutical Science ($1.34
million cash and $1.67 million grant shared)
2016 Warren Alpert Foundation Prize ($500,000).
2017 Albany Medical Center Prize in Medicine and
Biomedical Research ($500,000)
10
✓ Patentable subject matter should Not Predetermine but evolve with the technology today
✓ Invalidating Gene technologies based on patentable subject matter have directly and indirectly
adverse effect on global health care innovation
✓ Therefore, Gene technology should be excluded from patentable subject matter
1111
12

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Patentable Subject Matter” nurture or neglect innovation? A case study based rational analysis

  • 1. NURTURE NEGLECT Dara Ajay PhD, LLM Cheers Interactive. II-PIC: International Indian Patent Information Conference for Patent Information Professionals Disclaimer: The views and opinions expressed in this presentation are those of the authors and do not necessarily reflect the official policy or position of any governing body including Cheers Interactive.
  • 2. ❖Some of the related articles and sections from Patent Act and TRIPS India under Section 3 USA under Section 101 of Title 35 U.S.C. Australia under section 18 Malaysia under Section 13 China Article 25 European Patent Convention Article 52, 53 TRIPS Article 27.2 2 ➢what are not patentable • Frivolous/ obvious inventions • Contrary to well established natural laws • Contrary to public order or morality • Mere discovery of a scientific principle • Formulation of an abstract theory • Discovery of any living thing or non–living substance occurring in nature • Process for medicinal, surgical, curative, prophylactic, diagnostic, therapeutic or other treatment • Method of agriculture or horticulture • Plants & animals in whole or any part thereof • Method of performing mental act or method of playing game • Mathematical method or business method or algorithms or computer programme per se http://www.ipindia.nic.in/writereaddata/Portal/IPOAct/1_31_1_patent-act-1970-11march2015.pdf
  • 3. 3 ▪ The landmark case for Gene patenting is the Myriad Genetics, Inc., ▪ Developed a diagnostic kit which detect gene sequence BRCA1 and BRCA2 genes ▪ Unfortunately, Myriads high price (USD $3000-4000) https://en.wikipedia.org/wiki/BRCA_mutation
  • 4. 4 13th June 2013, US5747282, US5837492, US5693473, US5709999, US5710001, US5753441 and US6033857 Invalidate the claims of isolated gene under 35 U.S.C. §101 5 September 2014, AU686004 based on manner of manufacture indicating DNA and RNA as natural products and invention as artificial state of affairs November 2008 EP0705902, EP0705903, EP0699754, EP0785216 “natural law or natural product but ultimately whether it is for a mere discovery”
  • 5. 5 1. In Myriad case plaintiff failed to identify the anticompetitive practices 2. Weather gene isolation is mere discovery or invention ? BRCA1-17q21 BRCA2- 13q12.3 http://www.scinexx.de/dossier-bild-15-6-21210.html
  • 6. 6 CANCER The Cancer Statistics ✓~1.6 million new cases got registered with 35% dead rate ✓~ 14.1 million new cases reported with 8.2 million deaths ✓2020 prediction ~ 15 million new cases diagnosed, 12 million deaths ✓GLOBOCAN, 2025 estimation >19.3 million new cancer cases every year
  • 9. Feng Zhang @ Broad/MIT Jennifer Doudna @ Berkeley /HHMI CRISPR/ Cas9 Emmanuelle Charpentie @ Helmholtz MIMS/MHH 9http://www.brandeis.edu/now/2014/october/gabbay-award-2104.html http://blogs.plos.org/synbio/2017/10/05/when-will-crispr-get-a-nobel-prize/ “The discovery’s impact on medicine could be huge. Imagine being able to delete BRCA 1, the closely linked to breast cancer, or the that causes Huntington’s disease. The CRISPR/cas9 system puts scientists one step closer to being able to cure genetic disorders” CRISPRs, first observed in the 1980s 2014 Breakthrough Prize in Life Sciences ($3 million) 2015 Massry Prize ( $40,000) 2016 Canada Gairdner International Award ($100,000) 2016 Tang Prize in Biopharmaceutical Science ($1.34 million cash and $1.67 million grant shared) 2016 Warren Alpert Foundation Prize ($500,000). 2017 Albany Medical Center Prize in Medicine and Biomedical Research ($500,000)
  • 10. 10
  • 11. ✓ Patentable subject matter should Not Predetermine but evolve with the technology today ✓ Invalidating Gene technologies based on patentable subject matter have directly and indirectly adverse effect on global health care innovation ✓ Therefore, Gene technology should be excluded from patentable subject matter 1111
  • 12. 12