This case study presentation involves a 61-year-old male patient with Parkinson's disease, urinary tract infection, and severe edema. He has a history of Parkinson's disease for 8 years and has had a Foley catheter for 1 year. Physical examination finds the patient semiconscious with swelling over his entire body. Laboratory tests show elevated creatinine and sodium levels, as well as pus cells in the urine, indicating urinary tract infection. The patient is diagnosed with Parkinson's disease with urinary tract infection and bacterial endocarditis of prosthetic heart valves. The goals of therapy are to improve quality of life, prevent further complications, and optimize the patient's current treatment plan.
CASE STUDY ON UTI AND OBSTRUCTIVE JAUNDICERajesh Dutta
A 63-year old female presented with abdominal pain, yellow urine, and burning urination. Lab work showed elevated liver enzymes and bilirubin consistent with obstructive jaundice. Imaging revealed gallstones obstructing the common bile duct, causing jaundice. She was diagnosed with urinary tract infection, obstructive jaundice, and gallstones. Treatment included antibiotics, antacids, and antispasmodics.
Case on type II diabetes mellitus with peripheral neuropathy with hypertensionVineetha Menon
This document describes the case of a 38-year-old female patient admitted to the hospital for giddiness, generalized weakness, burning and tingling sensations in the lower limbs, and blurry vision. She has a history of type 2 diabetes for 3 years and hypertension for 1 year. On examination, she was found to have elevated blood pressure and blood glucose levels. She was diagnosed with type 2 diabetes with peripheral neuropathy and hypertension. Her symptoms improved with treatment including medications to control her blood pressure and blood glucose over her 5 day hospital stay.
This document summarizes the medical history and examination of a 49-year-old female patient presenting with increasing lower back, hip, and knee pain. The patient has a history of diabetes, deep vein thrombosis, and hypercholesterolemia. A physical examination revealed pain on motion of the hips and right knee crepitus. X-rays showed degenerative changes consistent with osteoarthritis in the lumbar spine, hips, and right knee. Laboratory tests showed elevated blood glucose, HbA1c, and cholesterol levels. The provisional diagnosis is osteoarthritis with diabetes and hypercholesterolemia.
This case presentation summarizes a 36-year-old male admitted with acute ischemic stroke presenting with right hemiparesis and reduced vision in the right eye. Diagnostic workup including CT scan revealed an acute infarct in the left occipito-parietal region. He was diagnosed with acute ischemic stroke and treated with medications including aspirin, clopidogrel, atorvastatin, and mannitol. His symptoms improved over his hospital stay and he was discharged on aspirin and clopidogrel with counseling on medication adherence and lifestyle modifications to prevent further complications.
CASE STUDY ON UTI AND OBSTRUCTIVE JAUNDICERajesh Dutta
A 63-year old female presented with abdominal pain, yellow urine, and burning urination. Lab work showed elevated liver enzymes and bilirubin consistent with obstructive jaundice. Imaging revealed gallstones obstructing the common bile duct, causing jaundice. She was diagnosed with urinary tract infection, obstructive jaundice, and gallstones. Treatment included antibiotics, antacids, and antispasmodics.
Case on type II diabetes mellitus with peripheral neuropathy with hypertensionVineetha Menon
This document describes the case of a 38-year-old female patient admitted to the hospital for giddiness, generalized weakness, burning and tingling sensations in the lower limbs, and blurry vision. She has a history of type 2 diabetes for 3 years and hypertension for 1 year. On examination, she was found to have elevated blood pressure and blood glucose levels. She was diagnosed with type 2 diabetes with peripheral neuropathy and hypertension. Her symptoms improved with treatment including medications to control her blood pressure and blood glucose over her 5 day hospital stay.
This document summarizes the medical history and examination of a 49-year-old female patient presenting with increasing lower back, hip, and knee pain. The patient has a history of diabetes, deep vein thrombosis, and hypercholesterolemia. A physical examination revealed pain on motion of the hips and right knee crepitus. X-rays showed degenerative changes consistent with osteoarthritis in the lumbar spine, hips, and right knee. Laboratory tests showed elevated blood glucose, HbA1c, and cholesterol levels. The provisional diagnosis is osteoarthritis with diabetes and hypercholesterolemia.
This case presentation summarizes a 36-year-old male admitted with acute ischemic stroke presenting with right hemiparesis and reduced vision in the right eye. Diagnostic workup including CT scan revealed an acute infarct in the left occipito-parietal region. He was diagnosed with acute ischemic stroke and treated with medications including aspirin, clopidogrel, atorvastatin, and mannitol. His symptoms improved over his hospital stay and he was discharged on aspirin and clopidogrel with counseling on medication adherence and lifestyle modifications to prevent further complications.
The document describes a 56-year-old male patient admitted with 8 days of high fever. Physical examination found the patient unconscious. Laboratory tests found Herpes Simplex Virus in the CSF. The diagnosis was viral meningitis. The treatment plan includes antiviral medication (Acyclovir) and supportive care, with monitoring of vital signs and symptoms over multiple days showing improvement.
case study - Urinary tract infection with diabetes mellitus Suvarta Maru
This document presents a case study of a 70-year-old female patient admitted to the hospital with a urinary tract infection and diabetes. The patient presented with fever, difficulty urinating, fatigue, pain, nausea, vomiting, burning urination, and weakness. Tests revealed a urinary tract infection with high blood sugar levels. She was given antibiotics and antidiabetic medications and advised on lifestyle changes to prevent future infections.
This case presentation discusses a 17-year-old male patient who presented with two episodes of seizures, vomiting, headache, unconsciousness, abnormal talking, and tightness in the limbs. Based on examination findings of perinatal hypoxia, mild cerebral atrophy, and abnormal EEG and brain mapping, the patient was diagnosed with primary generalized symptomatic seizures, auditory processing disorder, and mild mental retardation. The treatment plan included intravenous anti-seizure, antacid, anti-emetic, and antibiotic medications along with oral medications for discharge. The goals of treatment were to control seizure frequency and minimize side effects to allow for a normal life.
A 33-year-old female presented with severe cough, chest pain, vomiting, headache and fatigue. On examination, she had crackles in her lungs. Tests showed pneumonia in her right lung lobe. She was diagnosed with right lobar pneumonia and prescribed antibiotics, aspirin, pantoprazole, clopidogrel, atorvastatin, acetylcysteine, sorbitol, amlodipine, cetirizine and levofloxacin to treat the infection and reduce complications.
case presentation on cervical spondylosis by naveennaveen ramavatu
A 70-year-old female was admitted with complaints of giddiness, neck pain, headache, and leg pain. Diagnostic tests showed cervical spondylosis and hypertension. She was treated for 5 days with medications including pantoprazole, clopidogrel, rosuvastatin, betahistine, lorazepam, and lactulose. Her symptoms improved and she was discharged on a regimen including pantoprazole, clopidogrel, rosuvastatin, and betahistine to monitor for recurrence of symptoms.
A 16-year-old male presented with fever and joint pain for two days and one episode of vomiting. Laboratory tests found thrombocytopenia with a platelet count of 100,000. A dengue NS1 test was positive. He was diagnosed with acute febrile illness with dengue NS1+ and thrombocytopenia. Treatment included IV fluids, acetaminophen, ceftriaxone, pantoprazole, ondansetron, and doxycycline to reduce symptoms and prevent complications like dengue hemorrhagic fever. Monitoring of complete blood counts and repeat dengue testing was planned to monitor treatment progress and prevent complications.
Case Presentation on STROKE (Subarachnoid Hemorrhage)nayanadiv
A 45-year old female presented with generalized tiredness, drowsiness, confusion and seizures. Lab tests and CT scan revealed early hydrocephalus, a suspicious lesion in the fourth ventricle, and subarachnoid hemorrhage due to aneurysm rupture. She was admitted to the neuro ICU and started on treatments including dexamethasone, nimodipine, pantoprazole, paracetamol, fosphenytoin, mannitol and ondansetron to relieve symptoms, repair the bleeding vessel, prevent complications and recurrence. The pharmacist provided counseling on disease, drugs, lifestyle modifications and points to the physician regarding monitoring and potential drug interactions.
Case presentation on Cerebrovascular accident (Stroke)HAMMADKC
This document presents a case report of a 76-year-old male patient admitted to the neurology department with complaints of forgetting, left hand weakness, slurred speech, and incontinence. The patient has a history of hypertension, previous cerebrovascular accident, and fall from bed. Examination and investigations including MRI and angiogram confirmed the diagnosis of cerebrovascular accident. The patient was treated with medications like citicoline, levetiracetam, atorvastatin, and aspirin. His condition improved and he was discharged with advice on medications and lifestyle modifications to prevent further strokes.
A 36-year-old female presented with pain and tingling in her left hand and fingers that progressed to her arm and neck, as well as blurred vision in her right eye for 15 days. MRI revealed acute demyelinating optic neuritis. She was diagnosed with multiple sclerosis and right optic neuritis. Treatment included intravenous methylprednisolone, gabapentin, prednisolone, supplements, amlodipine for hypertension, and pantoprazole for acidity. Her medications, diet, disease monitoring, and follow up were discussed to manage her multiple sclerosis and symptoms.
This document presents case presentations for hypertension, diabetes mellitus, and community acquired pneumonia for a patient named Pooja. It summarizes the subjective and objective findings, assessments, diagnoses, etiologies, need for therapy, and current medications for each condition. It also provides information on common electrolyte solutions, assessments of current antihypertensive, antidiabetic, antibiotic, and other supportive care therapies including generic and brand names, mechanisms of action, administrations, adverse effects and contraindications.
This document summarizes the case of a 44-year-old male patient admitted to the hospital with seizures, vomiting, decreased appetite, and weakness in his limbs. Lab results found increased creatinine, BUN, and decreased chloride levels. A CT scan found no abnormalities in the brain but soft tissue swelling in the frontal region. Based on the subjective and objective patient data, the patient was diagnosed with a cerebrovascular accident, hypertension, and stage 4 chronic kidney disease. The treatment plan focused on rehabilitation, medication, monitoring the patient's condition, and counseling on lifestyle changes and managing the disease.
This document provides a morning report on a case of malaria. It summarizes the patient's history, including previous malaria infections, physical examination findings, laboratory test results showing Plasmodium vivax, and diagnosis of malaria tertiana. The patient's treatment plan includes IV fluids, antipyretics, anti-malarial medications, and patient education.
A 28-year-old male patient was admitted to the hospital with severe pain in his limbs and joints for the past four days, along with fever and bone pain. He has a history of sickle cell anemia. Laboratory tests showed microcytic hypochromic anemia. He was diagnosed with sickle cell anemia and prescribed IV fluids, antibiotics, analgesics, hydroxyurea, and supplements. Lifestyle modifications including folic acid, hydration, temperature control, and moderate exercise were also recommended.
The document describes a 67-year-old male patient presenting with dyspnea, constipation, anorexia, abdominal pain and headache. Examination finds the patient semiconscious and oriented with abdominal discomfort and tender abdomen. Laboratory investigations show abnormal renal function, electrolyte imbalance and signs of infection. The patient is diagnosed with septic shock with acute renal failure of unknown etiology. Treatment includes antibiotics, diuretics, bronchodilators and corticosteroids to address infection, fluid overload and organ dysfunction with the goals of improving quality of life and preventing further health complications.
A 47-year old female patient was admitted to the hospital with complaints of chest pain for one week, shortness of breath, and dizziness. Her medical history includes diabetes for 5 years and hypertension for 5 years. On examination, her blood pressure was elevated and blood sugar levels were high. An echocardiogram showed AV ischemia and normal left ventricular function. She was assessed as having diabetes, hypertension, and AV ischemia. The treatment plan is to control her blood sugar, blood pressure, improve medication adherence and lifestyle changes.
The document presents a case study of a 77-year-old male patient diagnosed with Parkinson's disease based on symptoms of slow movements, resting tremors, postural instability, and mask-like face. Laboratory tests and investigations revealed abnormalities. The patient was diagnosed with Parkinson's disease and mood disturbance. He was prescribed various medications including Syndopa Plus, Rosalect, and Loraazep and counseled on lifestyle modifications and managing his condition and medications.
Case presentation on gastroenteritis and acute renal failureDr P Deepak
A 42-year old female patient presented with gastroenteritis and acute renal failure. She reported loose stools and vomiting for several days. Laboratory tests found elevated urea and creatinine levels indicating acute renal failure. She was diagnosed with acute gastroenteritis caused by Entamoeba histolytica and treated with intravenous antibiotics, antiemetics, and proton pump inhibitors. Her condition improved over the next few days with reduced vomiting and stool frequency.
Rheumatoid arthritis with cervical myelopathyRiddhi Pawaskar
This document contains a case study of a 51-year-old female patient presenting with numbness and tingling in both lower limbs and pain. Her medical history includes rheumatoid arthritis, seizures, cervical myelopathy, respiratory infections, and ear infections. Examination findings and test results including MRI, bloodwork, urine analysis, and culture sensitivity are presented. Her hospital treatment course including medications and progress are documented.
A 45-year-old female patient presented with facial puffiness, myalgia, increased tiredness, hoarseness of voice and headache. Lab investigations revealed hypothyroidism. She was diagnosed with hypothyroidism and prescribed levothyroxine, otilonium bromide, ranitidine, ferrous sulfate, and calcium. The pharmacist intervened to recommend changing the dosing interval between levothyroxine and calcium to 4 hours apart to maximize levothyroxine efficacy and monitoring serum TSH levels.
The patient, P. Adilaxmi, a 35-year-old female, was diagnosed with a urinary tract infection and renal calculi complicated by type 2 diabetes. She presented with low backache, swelling of the lower limbs and face, and was on antidiabetic medication. Laboratory tests and ultrasound confirmed the diagnosis and showed renal abnormalities. She was treated with antibiotics, analgesics, and antidiabetic drugs, and her symptoms improved over time, allowing her discharge after 8 days.
Sub Acute Encephalopathy and Hemiparesis caseVasuki Vasuki
This document summarizes a patient's hospital admission and treatment. The 48-year-old female patient presented with giddiness and inability to walk, and was diagnosed with urosepsis, diabetes, and acute kidney injury. During her 3 day hospital stay she received various medications including insulin, antibiotics, and supplements. Her lab results showed abnormalities that were monitored and improved over her stay. She was counselled on medication adherence, diet, and symptom monitoring upon discharge.
The document describes a 56-year-old male patient admitted with 8 days of high fever. Physical examination found the patient unconscious. Laboratory tests found Herpes Simplex Virus in the CSF. The diagnosis was viral meningitis. The treatment plan includes antiviral medication (Acyclovir) and supportive care, with monitoring of vital signs and symptoms over multiple days showing improvement.
case study - Urinary tract infection with diabetes mellitus Suvarta Maru
This document presents a case study of a 70-year-old female patient admitted to the hospital with a urinary tract infection and diabetes. The patient presented with fever, difficulty urinating, fatigue, pain, nausea, vomiting, burning urination, and weakness. Tests revealed a urinary tract infection with high blood sugar levels. She was given antibiotics and antidiabetic medications and advised on lifestyle changes to prevent future infections.
This case presentation discusses a 17-year-old male patient who presented with two episodes of seizures, vomiting, headache, unconsciousness, abnormal talking, and tightness in the limbs. Based on examination findings of perinatal hypoxia, mild cerebral atrophy, and abnormal EEG and brain mapping, the patient was diagnosed with primary generalized symptomatic seizures, auditory processing disorder, and mild mental retardation. The treatment plan included intravenous anti-seizure, antacid, anti-emetic, and antibiotic medications along with oral medications for discharge. The goals of treatment were to control seizure frequency and minimize side effects to allow for a normal life.
A 33-year-old female presented with severe cough, chest pain, vomiting, headache and fatigue. On examination, she had crackles in her lungs. Tests showed pneumonia in her right lung lobe. She was diagnosed with right lobar pneumonia and prescribed antibiotics, aspirin, pantoprazole, clopidogrel, atorvastatin, acetylcysteine, sorbitol, amlodipine, cetirizine and levofloxacin to treat the infection and reduce complications.
case presentation on cervical spondylosis by naveennaveen ramavatu
A 70-year-old female was admitted with complaints of giddiness, neck pain, headache, and leg pain. Diagnostic tests showed cervical spondylosis and hypertension. She was treated for 5 days with medications including pantoprazole, clopidogrel, rosuvastatin, betahistine, lorazepam, and lactulose. Her symptoms improved and she was discharged on a regimen including pantoprazole, clopidogrel, rosuvastatin, and betahistine to monitor for recurrence of symptoms.
A 16-year-old male presented with fever and joint pain for two days and one episode of vomiting. Laboratory tests found thrombocytopenia with a platelet count of 100,000. A dengue NS1 test was positive. He was diagnosed with acute febrile illness with dengue NS1+ and thrombocytopenia. Treatment included IV fluids, acetaminophen, ceftriaxone, pantoprazole, ondansetron, and doxycycline to reduce symptoms and prevent complications like dengue hemorrhagic fever. Monitoring of complete blood counts and repeat dengue testing was planned to monitor treatment progress and prevent complications.
Case Presentation on STROKE (Subarachnoid Hemorrhage)nayanadiv
A 45-year old female presented with generalized tiredness, drowsiness, confusion and seizures. Lab tests and CT scan revealed early hydrocephalus, a suspicious lesion in the fourth ventricle, and subarachnoid hemorrhage due to aneurysm rupture. She was admitted to the neuro ICU and started on treatments including dexamethasone, nimodipine, pantoprazole, paracetamol, fosphenytoin, mannitol and ondansetron to relieve symptoms, repair the bleeding vessel, prevent complications and recurrence. The pharmacist provided counseling on disease, drugs, lifestyle modifications and points to the physician regarding monitoring and potential drug interactions.
Case presentation on Cerebrovascular accident (Stroke)HAMMADKC
This document presents a case report of a 76-year-old male patient admitted to the neurology department with complaints of forgetting, left hand weakness, slurred speech, and incontinence. The patient has a history of hypertension, previous cerebrovascular accident, and fall from bed. Examination and investigations including MRI and angiogram confirmed the diagnosis of cerebrovascular accident. The patient was treated with medications like citicoline, levetiracetam, atorvastatin, and aspirin. His condition improved and he was discharged with advice on medications and lifestyle modifications to prevent further strokes.
A 36-year-old female presented with pain and tingling in her left hand and fingers that progressed to her arm and neck, as well as blurred vision in her right eye for 15 days. MRI revealed acute demyelinating optic neuritis. She was diagnosed with multiple sclerosis and right optic neuritis. Treatment included intravenous methylprednisolone, gabapentin, prednisolone, supplements, amlodipine for hypertension, and pantoprazole for acidity. Her medications, diet, disease monitoring, and follow up were discussed to manage her multiple sclerosis and symptoms.
This document presents case presentations for hypertension, diabetes mellitus, and community acquired pneumonia for a patient named Pooja. It summarizes the subjective and objective findings, assessments, diagnoses, etiologies, need for therapy, and current medications for each condition. It also provides information on common electrolyte solutions, assessments of current antihypertensive, antidiabetic, antibiotic, and other supportive care therapies including generic and brand names, mechanisms of action, administrations, adverse effects and contraindications.
This document summarizes the case of a 44-year-old male patient admitted to the hospital with seizures, vomiting, decreased appetite, and weakness in his limbs. Lab results found increased creatinine, BUN, and decreased chloride levels. A CT scan found no abnormalities in the brain but soft tissue swelling in the frontal region. Based on the subjective and objective patient data, the patient was diagnosed with a cerebrovascular accident, hypertension, and stage 4 chronic kidney disease. The treatment plan focused on rehabilitation, medication, monitoring the patient's condition, and counseling on lifestyle changes and managing the disease.
This document provides a morning report on a case of malaria. It summarizes the patient's history, including previous malaria infections, physical examination findings, laboratory test results showing Plasmodium vivax, and diagnosis of malaria tertiana. The patient's treatment plan includes IV fluids, antipyretics, anti-malarial medications, and patient education.
A 28-year-old male patient was admitted to the hospital with severe pain in his limbs and joints for the past four days, along with fever and bone pain. He has a history of sickle cell anemia. Laboratory tests showed microcytic hypochromic anemia. He was diagnosed with sickle cell anemia and prescribed IV fluids, antibiotics, analgesics, hydroxyurea, and supplements. Lifestyle modifications including folic acid, hydration, temperature control, and moderate exercise were also recommended.
The document describes a 67-year-old male patient presenting with dyspnea, constipation, anorexia, abdominal pain and headache. Examination finds the patient semiconscious and oriented with abdominal discomfort and tender abdomen. Laboratory investigations show abnormal renal function, electrolyte imbalance and signs of infection. The patient is diagnosed with septic shock with acute renal failure of unknown etiology. Treatment includes antibiotics, diuretics, bronchodilators and corticosteroids to address infection, fluid overload and organ dysfunction with the goals of improving quality of life and preventing further health complications.
A 47-year old female patient was admitted to the hospital with complaints of chest pain for one week, shortness of breath, and dizziness. Her medical history includes diabetes for 5 years and hypertension for 5 years. On examination, her blood pressure was elevated and blood sugar levels were high. An echocardiogram showed AV ischemia and normal left ventricular function. She was assessed as having diabetes, hypertension, and AV ischemia. The treatment plan is to control her blood sugar, blood pressure, improve medication adherence and lifestyle changes.
The document presents a case study of a 77-year-old male patient diagnosed with Parkinson's disease based on symptoms of slow movements, resting tremors, postural instability, and mask-like face. Laboratory tests and investigations revealed abnormalities. The patient was diagnosed with Parkinson's disease and mood disturbance. He was prescribed various medications including Syndopa Plus, Rosalect, and Loraazep and counseled on lifestyle modifications and managing his condition and medications.
Case presentation on gastroenteritis and acute renal failureDr P Deepak
A 42-year old female patient presented with gastroenteritis and acute renal failure. She reported loose stools and vomiting for several days. Laboratory tests found elevated urea and creatinine levels indicating acute renal failure. She was diagnosed with acute gastroenteritis caused by Entamoeba histolytica and treated with intravenous antibiotics, antiemetics, and proton pump inhibitors. Her condition improved over the next few days with reduced vomiting and stool frequency.
Rheumatoid arthritis with cervical myelopathyRiddhi Pawaskar
This document contains a case study of a 51-year-old female patient presenting with numbness and tingling in both lower limbs and pain. Her medical history includes rheumatoid arthritis, seizures, cervical myelopathy, respiratory infections, and ear infections. Examination findings and test results including MRI, bloodwork, urine analysis, and culture sensitivity are presented. Her hospital treatment course including medications and progress are documented.
A 45-year-old female patient presented with facial puffiness, myalgia, increased tiredness, hoarseness of voice and headache. Lab investigations revealed hypothyroidism. She was diagnosed with hypothyroidism and prescribed levothyroxine, otilonium bromide, ranitidine, ferrous sulfate, and calcium. The pharmacist intervened to recommend changing the dosing interval between levothyroxine and calcium to 4 hours apart to maximize levothyroxine efficacy and monitoring serum TSH levels.
The patient, P. Adilaxmi, a 35-year-old female, was diagnosed with a urinary tract infection and renal calculi complicated by type 2 diabetes. She presented with low backache, swelling of the lower limbs and face, and was on antidiabetic medication. Laboratory tests and ultrasound confirmed the diagnosis and showed renal abnormalities. She was treated with antibiotics, analgesics, and antidiabetic drugs, and her symptoms improved over time, allowing her discharge after 8 days.
Sub Acute Encephalopathy and Hemiparesis caseVasuki Vasuki
This document summarizes a patient's hospital admission and treatment. The 48-year-old female patient presented with giddiness and inability to walk, and was diagnosed with urosepsis, diabetes, and acute kidney injury. During her 3 day hospital stay she received various medications including insulin, antibiotics, and supplements. Her lab results showed abnormalities that were monitored and improved over her stay. She was counselled on medication adherence, diet, and symptom monitoring upon discharge.
CASE PRESENTATION ON HEPATIC ENCEPHALOPATHY DUE TO ALCOHOLISMRahman Khan
- The patient, a 43-year-old male, presented with altered sensorium since the previous evening.
- He has a history of end-stage liver disease and portal hypertension with recurrent hepatic encephalopathy.
- On examination, he appeared drowsy and irritable. Investigations confirmed hepatic encephalopathy.
- He was diagnosed with hepatic encephalopathy due to alcoholism and prescribed medications including cefotaxime, pantoprazole, ondansetron, lactulose, ursodeoxycholic acid, rifaximin, and L-ornithine-L-aspartic acid to treat the condition and its symptoms.
A 24-year-old male was brought in after ingesting approximately 70 ml of an insecticide containing chlorpyriphosphate and cypermethrins. He was semiconscious on examination. Laboratory tests showed low serum cholinesterase levels and elevated ammonia levels. MRI brain showed small focal areas of abnormal signal intensity in the cerebellum, likely representing subacute ischemic infarcts. He was treated with pralidoxime, atropine, antibiotics, pantoprazole, ondansetron, meropenem, piperacillin/tazobactam, montelukast/fexofenadine, acebrophylline and furosemide to manage organ
13. a case study on convulsions in a kco epilepsy with lactational amenorrhoeaDr. Ajita Sadhukhan
A 25 year old female patient was admitted to the female medicine ward with complaints of 2 and a half month amenorrhoea, epileptic fit convulsions at home, vertigo, generalised weakness and 1 episode of epileptic fit today evening.
Emily is a 67-year-old woman presenting with epigastric pain, nausea, bloating and heartburn for 6 weeks. Physical examination revealed mild epigastric tenderness and stool heme positive. EGD showed a duodenal ulcer and biopsy indicated H. pylori infection. She was diagnosed with H. pylori-associated PUD and prescribed a triple therapy regimen to eradicate H. pylori along with PPI to promote ulcer healing. Her other conditions including CAD, hyperlipidemia, hypothyroidism and overweight were found to be well-controlled with current medical management. Lifestyle modifications and medication adherence were counselled.
A 42-year-old male patient was admitted to the hospital with abdominal distension, decreased appetite, and other symptoms due to chronic alcoholic liver disease. Laboratory tests showed elevated bilirubin and liver enzymes. The patient was diagnosed with alcoholic cirrhosis based on his history of alcohol abuse and laboratory results. He was counseled on lifestyle changes like reducing alcohol intake and a low-sodium diet to manage his condition.
This document provides an overview of pharmacotherapy for Parkinsonism. It discusses the clinical features and etiology of Parkinson's disease and outlines the mechanisms and uses of various drug classes for treatment, including levodopa, dopamine agonists, COMT inhibitors, MAO-B inhibitors, and other drugs. Side effects and considerations for each class are also reviewed. Non-motor symptoms can be treated with additional drugs like antidepressants, anxiolytics, and atypical antipsychotics as adjunctive therapy.
A 28-year-old female was admitted to the hospital for postpartum depression characterized by not feeding or accepting her baby and refusing to eat or speak. She was diagnosed with postpartum depression with cerebral venous thrombosis. Her treatment plan included levitaracetam, antibiotics, pantoprazole, ondansetron, enoxaparin, warfarin sodium, and mannitol to improve her quality of living and prevent complications while monitoring her platelet count and blood pressure. The physician recommended withdrawing levitaracetam, reducing anticoagulant doses due to her high platelet count, performing brain imaging, and adjusting anticoagulant dosing based on monitoring.
This document provides information on drugs used to treat peptic ulcer disease. It discusses proton pump inhibitors like omeprazole, pantoprazole, and rabeprazole which work by inhibiting acid production in the stomach. It also covers H2 receptor antagonists like ranitidine, cimetidine, and famotidine which block histamine receptors and reduce acid secretion. Other drug classes discussed are anticholinergics which decrease stomach motility, and misoprostol which has antisecretory and mucosal protective properties. The document provides details on the mechanisms, indications, dosages, and side effects of these various antiulcer drugs.
This case presentation summarizes the hospital admission of a 35-year-old male diagnosed with Grade II alcoholic liver disease and hepatic encephalopathy. He presented with fever, swelling of the feet and knees, loss of appetite, and sleep issues. His medical history revealed chronic alcohol use and tobacco chewing. On examination, he exhibited pallor, edema, and jaundice. Laboratory tests showed elevated liver enzymes. He was diagnosed with Grade II alcoholic liver disease and hepatic encephalopathy based on his symptoms, risk factors, and diagnostic tests. He was treated medically and counseled on lifestyle modifications and medication adherence.
This document provides information on nephrotic syndrome, specifically defining it as a clinical syndrome characterized by heavy proteinuria, hypoproteinemia, edema, and hypercholesterolemia. It describes the epidemiology, classification, pathophysiology, clinical manifestations, investigations, diagnosis, management, and prognosis of nephrotic syndrome. The key points are that minimal change disease is the most common type, presenting with edema, ascites, weight gain, and respiratory distress in children aged 1-10 years. Investigations show proteinuria, hypoalbuminemia, and normal renal function. Management involves steroid therapy, addressing complications, and educating parents on infection prevention and immunization.
The document provides information on several drugs including their actions, indications, contraindications, side effects, and nursing considerations. It includes summaries of Ranitidine (anti-ulcer drug), Ketorolac (non-steroidal anti-inflammatory), Metronidazole (anti-infective), Paracetamol/Acetaminophen (analgesic/antipyretic), Celecoxib (non-steroidal anti-inflammatory), Cefixime (antibiotic), Omeprazole (proton pump inhibitor), and Amino acid sorbitol (parenteral nutrition). The nursing responsibilities focus on assessing patients, monitoring for side effects and allergic reactions,
1. Mr. Al-Momtan, a 56-year-old male, presented with epigastric abdominal pain for 2 weeks which was worse after eating. Clinical exams and tests diagnosed him with a peptic ulcer disease.
2. He was prescribed a triple therapy of antibiotics and a PPI for 3 weeks to treat his condition.
3. Dyspepsia is a common gastrointestinal condition with many potential causes including non-ulcer dyspepsia, GERD, peptic ulcers, and H. pylori infection. Guidelines recommend lifestyle changes, antacids, and empirical PPI therapy as first-line treatment options.
Common Lab Investigations in pregnancy with reference to Anaemia, Leukocytosi...DrNisheethOza
There are no standardized guidelines/protocols for conducting common laboratory investigations during pregnancy. Here is an attempt to educate Pregnant ladies in this important aspect of their healthcare.
This document presents a case of a 58-year-old male with nephrotic syndrome. The patient presented with leg swelling, lower urinary tract symptoms, and respiratory difficulty. Laboratory tests showed proteinuria, hypoalbuminemia, and hyperlipidemia. The patient was diagnosed with nephrotic syndrome and stage 1 hypertension. The treatment plan included medications to relieve symptoms, lower cholesterol, improve kidney function, eliminate fluid accumulation, and improve quality of life. The pharmacist provided interventions on monitoring for adverse effects and recommended diet and lifestyle modifications.
This case involves a 30-year old woman presenting with a wide range of symptoms over 12 months including fatigue, arthritis, rashes, oral ulcers, hair loss, and kidney problems. Physical exam and lab tests confirmed she meets enough criteria for a diagnosis of systemic lupus erythematosus (SLE) with class IV lupus nephritis. Her treatment plan includes cyclophosphamide, steroids, ACE inhibitors, and later azathioprine to control her SLE and protect her kidneys. Her response is being monitored through disease markers and renal function.
A blockage of blood flow to the heart muscle. A heart attack is a medical emergency.A heart attack usually occurs when a blood clot blocks blood flow to the heart.Without blood,tissues loses oxygen and dies
Basavarajeeyam is a Sreshta Sangraha grantha (Compiled book ), written by Neelkanta kotturu Basavaraja Virachita. It contains 25 Prakaranas, First 24 Chapters related to Rogas& 25th to Rasadravyas.
Histololgy of Female Reproductive System.pptxAyeshaZaid1
Dive into an in-depth exploration of the histological structure of female reproductive system with this comprehensive lecture. Presented by Dr. Ayesha Irfan, Assistant Professor of Anatomy, this presentation covers the Gross anatomy and functional histology of the female reproductive organs. Ideal for students, educators, and anyone interested in medical science, this lecture provides clear explanations, detailed diagrams, and valuable insights into female reproductive system. Enhance your knowledge and understanding of this essential aspect of human biology.
share - Lions, tigers, AI and health misinformation, oh my!.pptxTina Purnat
• Pitfalls and pivots needed to use AI effectively in public health
• Evidence-based strategies to address health misinformation effectively
• Building trust with communities online and offline
• Equipping health professionals to address questions, concerns and health misinformation
• Assessing risk and mitigating harm from adverse health narratives in communities, health workforce and health system
Cell Therapy Expansion and Challenges in Autoimmune DiseaseHealth Advances
There is increasing confidence that cell therapies will soon play a role in the treatment of autoimmune disorders, but the extent of this impact remains to be seen. Early readouts on autologous CAR-Ts in lupus are encouraging, but manufacturing and cost limitations are likely to restrict access to highly refractory patients. Allogeneic CAR-Ts have the potential to broaden access to earlier lines of treatment due to their inherent cost benefits, however they will need to demonstrate comparable or improved efficacy to established modalities.
In addition to infrastructure and capacity constraints, CAR-Ts face a very different risk-benefit dynamic in autoimmune compared to oncology, highlighting the need for tolerable therapies with low adverse event risk. CAR-NK and Treg-based therapies are also being developed in certain autoimmune disorders and may demonstrate favorable safety profiles. Several novel non-cell therapies such as bispecific antibodies, nanobodies, and RNAi drugs, may also offer future alternative competitive solutions with variable value propositions.
Widespread adoption of cell therapies will not only require strong efficacy and safety data, but also adapted pricing and access strategies. At oncology-based price points, CAR-Ts are unlikely to achieve broad market access in autoimmune disorders, with eligible patient populations that are potentially orders of magnitude greater than the number of currently addressable cancer patients. Developers have made strides towards reducing cell therapy COGS while improving manufacturing efficiency, but payors will inevitably restrict access until more sustainable pricing is achieved.
Despite these headwinds, industry leaders and investors remain confident that cell therapies are poised to address significant unmet need in patients suffering from autoimmune disorders. However, the extent of this impact on the treatment landscape remains to be seen, as the industry rapidly approaches an inflection point.
TEST BANK For Basic and Clinical Pharmacology, 14th Edition by Bertram G. Kat...rightmanforbloodline
TEST BANK For Basic and Clinical Pharmacology, 14th Edition by Bertram G. Katzung, Verified Chapters 1 - 66, Complete Newest Version.
TEST BANK For Basic and Clinical Pharmacology, 14th Edition by Bertram G. Katzung, Verified Chapters 1 - 66, Complete Newest Version.
TEST BANK For Basic and Clinical Pharmacology, 14th Edition by Bertram G. Katzung, Verified Chapters 1 - 66, Complete Newest Version.
TEST BANK For Basic and Clinical Pharmacology, 14th Edition by Bertram G. Katzung, Verified Chapters 1 - 66, Complete Newest Version.
2. SUBJECTIVE DATA
NAME: NBK AGE: 61 SEX: M Weight: 60 kg Height: 168cms
CHIEF COMPLAINTS:
• Dribbling of urine(Foley’s Catheter)
P D U T I B P H : P A W A S K A R R M
2
3. OBJECTIVE DATA
• MEDICAL H/O: Parkinson’s d/o since 8Y, on Foley’s Catheter since 1y
No h/o DM,HTN
• SOCIAL H/O: Married, Clerkship in a bank
• FAMILY H/O: A relative with Alzheimer’s( diagnosed at age 68)
• PREVIOUS ALLERGIES: N/S
P D U T I B P H : P A W A S K A R R M
3
4. PREVIOUS MEDICATIONS
1. TB. Tidomet TDS Levodopa (100mg) + Carbidopa
(25mg)
11.Tb Tramagold SOS Tramadol+ Paracetamol
2 Tb.Pramipex BD Pramipexole HCl 0.25mg 12 Tb Ciplar OD Ciprofloxacin
3 Tb Parkitidin BD Amantadine 100mg 13 Tb Amiflox OD Amoxicillin
4 Tb Renolog OD α-ketoanalog+L-Histidine 14 Tb Xolid OD Linezolid
5Tb Sobsis Forte BD 15 Syp Hepatoglobin Folic Acid+Vit B12
6 Tb Protin-m SOS Drotavarine+Mefanamic acid 16 Syp Renikare TDS 1tsp
7 Cap Urimax OD Tamsulosin 0.4mg 17 Prohance Powder TDS 1tsp
8 Tb Mondeslor prn Montelukast+Desloratidine 18 Tb Fulzaren TDS Faropenem 200mg
9 Tb Nootropil BD Piracetam 10 mg 19 Tb Clopitab OD Clopidogrel
10 Tb Novastat TDS Novastatin 10mg
P D U T I B P H : P A W A S K A R R M
4
5. PHYSICAL EXAMINATION
• GENERAL: semiconscious, afebrile, swelling over entire body
• VITALS: BP- 150/90 Pulse: 78/min SpO2: 96% RR: 24/min
• HEENT: N
• CVS: N
• CNS: semiconscious, responds to verbal commands, doesn’t move or talk
• GIT: ET feeding- 200ml/4h; palpatous,tender
• GU: prostatomegaly, obstructive uropathy,
P D U T I B P H : P A W A S K A R R M
5
6. CBC
Hb- 13.8 g/dl
HCT- 37.9
PLT-197
ROUTINE ANALYSIS
LAB INVESTIGATION
S.BUN-
12.0mg/dL
S.Creat-1.2mg/dL
SGPT-13.4 U/L
D.Bil-0.3
I.Bil-0.5
T.Bil-0.8
ALP-89IU/L
S.Alb-3.1g/dL
S.Glob-2.7g/Dl
S.Na-118mEq/L
S.K-4.7mEq/L
S.Glu-99mg/dL
ABG
pH-7.45
pCO2- 30mm Hg
pO2- 62 mm Hg
HCO3- 20.9mmol/L
TCO2- 21.8mmol/L
Beb- 2.1mmol/L
BEecf- 3.1mmol/L
SBC-23.1mmol/L
P D U T I B P H : P A W A S K A R R M
6
7. URINALYSIS
Sugar- Nil
Bile salts-Absent
Bile proteins- Absent
Microscopic:
a) 70-80 pus cells
b) 2-3 RBCs with bacteria++
c) HPF
C-XR: Chest P/A
o RT noted in situ
o Mild cardiomegaly
o Soft tissue, bony cage reveal normal
features
o Central trachea: Both
hemidiaphragms normal
o Both lung fields normal
o Pulmonary vasculature normal
o IMP: mild cardiomegaly
OTHER INVESTIGATIONS
P D U T I B P H : P A W A S K A R R M
7
8. USG
Moderate ascitis
ECG
QT prolongation
MRI
• Mild BIL Mastoiditis is seen(L>R)
• Few acute non haemorrhagic Lacunar infarcts
in Left corona radiata
• Extreme deepmicrovasculature ischemic foci
in BIL ganglio capsular being chronic lacunar
infarcts
• Mild age appropriate cerebral & cerebellar
atrophy
FURTHER INVESTIGATIONS
P D U T I B P H : P A W A S K A R R M
8
11. Final Diagnosis
ETIOLOGY
Goals of Therapy
• Parkinson’s d/o with UTI with
BEP
• Possible outcome: CKD
• Age
• Sleep cycle disturbance
• To increase quality of life
• Prevent comorbidity, mortality &
further progression of disorder
• Reduce adverse events of current
therapy and optimize therapy
ASSESSMENT TO CURRENT THERAPY
P D U T I B P H : P A W A S K A R R M
12
12. MOA: Carbapenems inhibit bacterial cell wall synthesis by binding to the penicillin-binding
proteins and interfering with cell wall formation.
CATEGORY: Antibacterial, Carbapenem
INDICATIONS: Intraabdominal Infection, Nosocomial Pneumonia, Skin and Structure Infectio
nSkin or Soft Tissue Infection, Meningitis
CONTRAINDICATIONS: Seizure
ADVERSE EVENTS: Constipation ,redness, swelling at the injection site, thrombocytopenia
PREGNANCY: US FDA pregnancy category: B
PRECAUTIONS: Tell your doctor about all your other medicines, especially:
divalproex sodium;
probenecid; or
valproic acid.
STD. DOSE: Reconstitute infusion vials containing 500 mg or 1 g with a compatible IV
solution (e.g., 0.9% sodium chloride, 5% dextrose) to provide solutions containing
approximately 2.5–50 mg/mL.
INJ MEROPENEM IV TDS
500MG(D1-D2)
P D U T I B P H : P A W A S K A R R M
13
13. GENERIC: Levodopa (100mg) + Carbidopa (25mg)
CATEGORY: Anti Parkinsonian
MOA: Levodopa is converted to dopamine via the action of a naturally occurring enzyme called DOPA
decarboxylase. Carbidopa prevents peripheral conversion of levodopa to dopamine and thereby reduces the
unwanted peripheral side effects of levodopa
INDICATIONS: Parkinson’s associated symptoms, Lewy body dementia
CONTRAINDICATIONS: Concomitant use with a nonselective MAO inhibitor. Angle-closure glaucoma.,
Known hypersensitivity to levodopa, carbidopa,
ADVERSE EVENTS: syncope, depression, hallucination, sleep disturbance, Dyskinesias (choreiform, dystonic,
other adventitious movements)
PREGNANCY: Category C
PRECAUTIONS: safety and efficacy not established in children <18 years of age
STD. DOSE: Available in combination products containing a 1:4 or 1:10 ratio of carbidopa to levodopa
TB. TIDOMOT FORTE TDS(D1-D2)
P D U T I B P H : P A W A S K A R R M
14
14. GENERIC: Pramipexole
CATEGORY: Anti Parkinsonian
MOA: Pramipexole binds to dopamine receptors and mimics the actions of dopamine, a naturally
occurring neurotransmitter.
INDICATIONS: Parkinson’s associated symptoms, Restless leg syndrome
CONTRAINDICATIONS: Seizure, Psychosis, Lactation
ADVERSE EVENTS: drowsiness, visual hallucination, constipation, and insomnia. Other side
effects include: xerostomia.
PREGNANCY: Not assigned. There are no adequate data on the developmental risks associated
with use of this drug in pregnant women; based on animal data, this drug may cause fetal harm.
PRECAUTIONS: Do not stop using pramipexole suddenly, or you could have unpleasant
withdrawal symptoms. Follow your doctor's instructions about tapering your dose.
STD.DOSE: Initial dose: 0.375 mg orally once a day
Titration: Increase gradually no more frequently than every 5 to 7 days, first dose increase should be
to 0.75 mg once a day followed by incremental increases of 0.75 mg; assess therapeutic response and
tolerability at a minimum of 5 days after each dose increase.
Maximum dose: 4.5 mg per day
TB. PRAMIPRO BD 0.75MG(D2+)
P D U T I B P H : P A W A S K A R R M
15
15. GENERIC: Sodium Bicarbonate
CATEGORY: Systemic alkaliser
MOA: Dissociates to provide bicarbonate ion which neutralizes hydrogen ion concentration and
raises blood and urinary pH
INDICATIONS: Heartburn, indigestion, constipation, GERD,Metabolic acidosis,
Hyperkalemia
CONTRAINDICATIONS: Alkalosis, hypernatremia, severe pulmonary edema, hypocalcemia,
unknown abdominal pain
ADVERSE EVENTS: Frequent urge to urinate, headache (continuing)loss of appetite
(continuing)mood or mental changes, muscle pain or twitching, nausea or vomiting,
nervousness or restlessness, slow breathing, swelling of feet or lower legs, unpleasant taste,
unusual tiredness or weakness
PREGNANCY: Not assigned. Do not use this medicine without a doctor's advice if you
are pregnant.
PRECAUTIONS: Ask a doctor or pharmacist before taking sodium bicarbonate if you are on a
low-salt diet, or if you have high blood pressure.
STD. DOSE: For urinary alkalinization: 325 to 2000 mg orally 1 to 4 times a day. One gram
provides 11.9 mEq (mmoL) each of sodium and bicarbonate
TB. SOBISIS FORTE 1G OD(D1-D2)
P D U T I B P H : P A W A S K A R R M
16
16. GENERIC: Tamsulosin
CATEGORY: alpha adrenergic antagoinist
MOA: Tamsulosin is an antagonist of alpha1A-adrenoreceptors in the prostate. Smooth muscle
tone in the prostate is mediated by alpha1A-adrenoreceptors; blocking them leads to relaxation of
smooth muscle in the bladder neck and prostate causing an improvement of urine flow and
decreased symptoms of BPH
INDICATIONS: BPH, Chronic prostatis, ureteral caliculi expulsion, ureteral stent related urinary
symptoms
CONTRAINDICATIONS: Concomitant use with strong CYP3A4 inhibitors (including
ketoconazole), hypersensitivity
ADVERSE EVENTS: difficulty in urination, hypotension, rhinitis, nasal congestion,fever,
drowsiness
PREGNANCY: tamsulosin is not FDA approved for use in women or children
PRECAUTIONS: Your blood pressure will need to be checked often. You will also need to be
checked for prostate cancer before and during treatment with tamsulosin.
STD. DOSE: Initial and Maintenance: 0.4 mg once daily. If response is inadequate after 2 to 4
weeks, may increase to 0.8 mg once daily. If therapy is discontinued or interrupted for several days,
restart with 0.4 mg once daily. Max Dose; 0.8mg
CAP. URIMAX 0.4MG OD(D1-D2)
P D U T I B P H : P A W A S K A R R M
17
17. GENERIC: Tolvaptan
CATEGORY: Antidiuretic
MOA: An arginine vasopressin (AVP) receptor antagonist with affinity for AVP receptor subtypes
V2 and V1a in a ratio of 29:1. Antagonism of the V2 receptor by tolvaptan promotes the excretion of
free water (without loss of serum electrolytes) resulting in net fluid loss, increased urine output,
decreased urine osmolality, and subsequent restoration of normal serum sodium levels.
INDICATIONS: Autosomal dominant polycystic kidney disease, Hypervolemic or
euvolemic hyponatremia
CONTRAINDICATIONS: Hypersensitivity, atients with a history, signs, or symptoms of
significant liver impairment or injury
ADVERSE EVENTS: polyuria, increased thirst, pollakiuria, and xerostomia. Other side effects
include: constipation, fever, hyperglycemia, increased serum alanine aminotransferase, and anorexia.
PREGNANCY: US FDA pregnancy category C
PRECAUTIONS: Grapefruit juice may increase tolvaptan serum concentrations. Management:
Avoid concurrent use with grapefruit juice
STD. DOSE: Initial: 15 mg once daily; after at least 24 hours, may increase to 30 mg once daily to a
maximum of 60 mg once daily titrating at 24-hour intervals to desired serum sodium concentration.
Avoid fluid restriction during the first 24 hours of therapy. Do not use for more than 30 days due to
the risk of hepatotoxicity.
TB. HYPONAT –O 15MG OD(D2+)
P D U T I B P H : P A W A S K A R R M
18
18. GENERIC: Piracetam
CATEGORY: Central sstimulant
MOA: Piracetam is a positive allosteric modulator of the AMPA receptor, Piracetam
may exert its global effect on brain neurotransmission via modulation of ion
channels (i.e., Na+, K+).
INDICATIONS: Cortical myoclonus, Cognitive enhancer, Dementia, Alzheimer's
disease, Dyslexia
CONTRAINDICATIONS: Hepatic impairment, Severe renal impairment,
Pregnancy, lactation, Hemorrhagic diathesis
ADVERSE EVENTS: Blood dyscrasia, renal impairment, impair abilities to drive or
perform hazardous tasks.
PREGNANCY: This medicine is not recommended for use by pregnant women
unless absolutely necessary and the benefits outweigh the risk associated.
PRECAUTIONS: The use of this medicine should not be discontinued abruptly as
some patients may feel symptoms of withdrawal.
STD. DOSE: Adult: 1.6-9.6 g/day orally
TB. NOOTROPIL BD(D2+)
P D U T I B P H : P A W A S K A R R M
19
19. GENERIC: Levo-carnitine, Coenzyme Q10, L-Arginine, Vitamin E, Lycopene,
Methylcobalamin, Zinc, and Selenium as active ingredients
CATEGORY: nutritional supplement
MOA: It controls the levels of levocarnitine, in patients who suffer from problems with
metabolism.
INDICATIONS: Nutritional deficiencies. It is used therapeutically to stimulate gastric and
pancreatic secretions and in the treatment of hyperlipoproteinemias.
CONTRAINDICATIONS: Hypersensitivity
ADVERSE EVENTS: Fever, seizures, arrhythymias, cramp in the stomach and abdomen,
nausea, headache, and diarrhea.
PREGNANCY: This medication is extremely unsafe to be used during pregnancy. Studies
carried out on humans and animals have shown significant adverse effects on the fetus. Doctor
consultation is recommended in such cases.
PRECAUTIONS: This medication may cause excessive drowsiness and calmness with alcohol.
STD. DOSE: 1 tablet per day. Missed dose should be taken as soon as possible. It is
recommended to skip your missed dose, if it is the time for your next scheduled dose.
TB.COMPLETE DT(D2+)
P D U T I B P H : P A W A S K A R R M
20
20. GENERIC: Selegiline
CATEGORY: Anti parkinsonian
MOA: At lower doses, selegiline can serve as a selective inhibitor of MAO-B; however, as selegiline concentrations
increase, MAO-B selectivity is lost. Selegiline may increase dopaminergic activity by interfering with dopamine
reuptake at the synapse. Effects may also be mediated through its metabolites, including amphetamine and
methamphetamine, which interfere with neuronal uptake and enhance release of several neurotransmitters
INDICATIONS: Parkinson’s Disease, Major Depressive Disorder, ADHD
CONTRAINDICATIONS: hypersensitivity, Concomitant use of methadone, other MAO inhibitors (selective or
non-selective), propoxyphene, or tramadol within 14 days of selegiline; concomitant use with cyclobenzaprine,
dextromethorphan, or St John’s wort
ADVERSE EVENTS: application site reaction, dizziness, insomnia, and nausea. Other side effects
include: abdominal pain, skin rash, weight loss, and orthostatic hypotension.
PREGNANCY: US FDA pregnancy category C
PRECAUTIONS: Avoid or limit tyramine-containing foods/beverages (product and/or dose-dependent). Some
examples include aged or matured cheese, air-dried or cured meats (including sausages and salamis), fava or broad
bean pods, tap/draft beers, Marmite concentrate, sauerkraut, soy sauce and other soybean condiments. Food’s
freshness is also an important concern; improperly stored or spoiled food can create an environment where tyramine
concentrations may increase
STD. DOSE: Oral tablet:
Recommended dose: 5 mg orally twice a day
Maximum dose: 10 mg orally per day
TB. SELGIN 5MG BD(D1-D2)
P D U T I B P H : P A W A S K A R R M
21
21. GENERIC: Rosuvastatin
CATEGORY: Antihyperlipidemic
MOA: Inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase, the rate-
limiting enzyme in cholesterol synthesis (reduces the production of mevalonic acid from HMG-
CoA); this then results in a compensatory increase in the expression of LDL receptors on
hepatocyte membranes and a stimulation of LDL catabolism.
INDICATIONS: hyperlipidemias, hyperlipoproteinemia, CV risk prevention, Atherosclerosis,
CONTRAINDICATIONS: Hypersensitivity to rosuvastatin or any component of the
formulation; active liver disease; unexplained persistent elevations of serum transaminases;
pregnancy; breastfeeding
ADVERSE EVENTS: myalgia, asthenia, tender swollen glands in neck.
PREGNANCY: US FDA pregnancy category: X
PRECAUTIONS: Seek urgent medical advice and consider temporarily withholding
rosuvastatin if you develop any acute muscle pain or have another condition that may increase
your risk of serious muscle injury or kidney failure such as a severe infection, major surgery,
trauma, uncontrolled seizures, severe electrolyte or metabolic disorders.
STD. DOSE: Initial dose: 10 mg to 20 mg orally once a day
Maintenance dose: 5 mg to 40 mg orally once a day
TB. NOVASTAT 10MG OD(D2+)
P D U T I B P H : P A W A S K A R R M
22
22. GENERIC: Univestin, Glucosamine sulfate, Chondroitin, MSM and
Vitamin D3 as active ingredients
MOA: A natural formulation with anti-inflammatory and chondroprotective
properties
INDICATIONS: Bone, cartilage and joint disorders
STD. DOSE: - As directed by the physician.
Key benefits/Uses of Trivestin:
- Glucosamine is a nutritional supplement and is used in the treatment of osteoarthritis and rheumatoid arthritis.
- Glucosamine stimulates the production of cartilage, which leads to joint repair. It also maintains elasticity, strength, and
resiliency of the cartilage in movable joints.
- Vitamin D helps the body to use more of the calcium found in foods and supplements.
- Univestin inhibits the enzymes responsible for inflammation thereby reducing joint discomfort and rigidity. It also
improves flexibility and physical function.
- Chondritin works with glucosamine to treat Osteoarthritis.
- Formulation repairs and restores cartilage, bones, and joints.
TB. TRIVESTIN BD(D2+)
P D U T I B P H : P A W A S K A R R M
23
25. Add Title
Add Title
Add Title
Add Title
Add Title
Add Title
PATIENT NAME: XYZ HOSP. NO:
AGE: yr WEIGHT: kg
SEX: M/F:Male
DATE OF ADMISSION: 11 /02/18
DATE OF DISCHARGE: 14/02/18
COMPLAINTS ON ADMISSION :
MEDICAL HISTORY :
MEDICATION HISTORY : -
SOCIAL HISTORY:
FAMILY HISTORY: NS
PREVIOUS ALLERGIES: N/S
PHYSICAL EXAMINATION: moderately build and nourished, conscious and co-
operative
GENERAL - no P I C C L E
VITAL SIGNS - PR: 90 /min ; BP : 110/80mmhg, R.R:- N/A,
HEENT - N/S
CVS - S1 S2 heard; no murmurs
RS - N/S
GIT - N/S
GU - N/S
EXT - reflexes were normal.
CNS - conscious and oriented
PROVISIONAL DIAGNOSIS:
ROUTINE BIOCHEMICAL INVESTIGATIONS HAEMATOLOGY:
Urea: mg/dl
S.Cr :mg/dl
Na: mEq/L
K: mEq/L
FBS:
PPBS:
RBS:
Tch :
TGs :
T Bili:
D Bili:
T. Prot:
Alb
:
Glo
b:
AS
T:
AL
T:
AL
P:
RBC : Retics:
WBC: Hb:
N: PCV:
L: MCV:
M: MCH:
E: MCHC:
B: ESR:
Platelets:.
URINE ANALYSIS OTHERS
pH: WBC:
Protein RBC:
Sugars: EP.
Blood: Casts:
Crystals:
Stool –
ECG -
FINAL DIAGNOSIS:- Acute wall MI
DRUG WITH DOSE & ROUTE
DURATION OF THERAPY
GENERIC NAME BRAND NAME
1
2
3
4
5
6
7
8
9
8
8
√ √ √ √
√
√ √ √ √
√ √ √ √
√
DISCHARGE MEDICATIONS:
DISCHARGE MEDICATIONS:
Patient not discharged
DAY INVESTIGATIONS
D1
D2
D3
PR – beats/min
BP – mmHg
PR – 80 beats/min
BP – mmHg
PR – 86 beats/min
BP – 100/80 mmHg
REVIEW:
Visit after 1 week
DRUG TREATMENT CHART: PROGRESS CHART:
Medication Dose and
duration
1 2 3 4 5
26. Add Title
Add Title
Add Title
Add Title
Add Title
Add Title
PATIENT NAME: XYZ HOSP. NO:
AGE: yr WEIGHT: kg SEX:
M/F:Male
DATE OF ADMISSION: 11 /02/18
DATE OF DISCHARGE: 14/02/18
COMPLAINTS ON ADMISSION :
MEDICAL HISTORY :
MEDICATION HISTORY : -
SOCIAL HISTORY:
FAMILY HISTORY: NS
PREVIOUS ALLERGIES: N/S
PHYSICAL EXAMINATION: moderately build and nourished, conscious and co-operative
GENERAL - no P I C C L E
VITAL SIGNS - PR: 90 /min ; BP : 110/80mmhg, R.R:- N/A,
HEENT - N/S
CVS - S1 S2 heard; no murmurs
RS - N/S
GIT - N/S
GU - N/S
EXT - reflexes were normal.
CNS - conscious and oriented
PROVISIONAL DIAGNOSIS:
ROUTINE BIOCHEMICAL INVESTIGATIONS HAEMATOLOGY:
Urea: mg/dl
S.Cr :mg/dl
Na: mEq/L
K: mEq/L
FBS:
PPBS:
RBS:
Tch :
TGs :
T Bili:
D Bili:
T. Prot:
Alb:
Glo
b:
AST
:
ALT
:
ALP
:
RBC : Retics:
WBC: Hb:
N: PCV:
L: MCV:
M: MCH:
E: MCHC:
B: ESR:
Platelets:.
URINE ANALYSIS OTHERS
pH: WBC:
Protein RBC:
Sugars: EP.
Blood: Casts:
Crystals:
Stool –
ECG -
FINAL DIAGNOSIS:- Acute wall MI
DRUG WITH DOSE & ROUTE
DURATION OF THERAPY
GENERIC NAME BRAND NAME
1
2
3
4
5
6
7
8
9
8
8
√ √ √ √
√
√ √ √ √
√ √ √ √
√
DISCHARGE MEDICATIONS:
DISCHARGE MEDICATIONS:
Patient not discharged
DAY INVESTIGATIONS
D1
D2
D3
PR – beats/min
BP – mmHg
PR – 80 beats/min
BP – mmHg
PR – 86 beats/min
BP – 100/80 mmHg
REVIEW:
Visit after 1 week
DRUG TREATMENT CHART: PROGRESS CHART:
Medication Dose and
duration
1 2 3 4 5
27. PLANNING
THERAPEUTIC MONITORING:
TOXICITY MONITORING:
DISCHARGE MONITORING:
DISCHARGE MEDICATIONS:
P D U T I B P H : P A W A S K A R R M
30
28. POINT TO PATIENT
About the disease:
About lifestyle modifications:
About medications:
P D U T I B P H : P A W A S K A R R M
31
29. POINT TO PHYSICIAN
When used as an adjunct to levodopa/carbidopa in the treatment of Parkinson's disease,
selegiline may enhance levodopa-associated side effects in some patients. The presumed
mechanism is enhanced peripheral catecholamine availability due to decreased
degradation (MAOI activity) and increased synthesis (levodopa effect) of dopamine and,
probably, norepinephrine.. MANAGEMENT: Two to three days after adding selegiline
to the regimen, the levodopa/carbidopa dosage may require reduction by 10% to 30%. It
has been suggested that the dosage reduction should be gradual in increments of 10%
every 3 to 4 days and concurrent use should be avoided in patients with postural
hypotension.
ADJUST DOSING INTERVAL: The oral bioavailability and pharmacologic effects of
levodopa and carbidopa may be decreased during concurrent administration with iron-
containing products..
The hypotensive effects of levodopa and antihypertensive agents may be additive.
Postural hypotension may occur.. MANAGEMENT: Hemodynamic responses should
be monitored during coadministration, especially during the first few weeks of therapy.
Dose adjustments of the antihypertensive agent may be required.
P D U T I B P H : P A W A S K A R R M
32
30. POINT TO PHYSICIAN
ADJUST DOSE: Pramipexole may potentiate the dopaminergic side effects of levodopa,
resulting in development or exacerbation of dyskinesia
SODIUM BICARBONATE AND ROSUVASTATIN: ADJUST DOSING INTERVAL:
Coadministration with antacids or agents with acid-neutralizing effects may reduce the
oral bioavailability of rosuvastatin. The mechanism of interaction has not been
established but may involve a pH-dependent reduction in drug dissolution and
absorption.
MONITOR: Monoamine oxidase inhibitors (MAOIs) may potentiate the hypotensive
effect of some medications. MAOIs alone quite commonly produce orthostatic
hypotension. Close monitoring for development of hypotension is recommended.
Ambulatory patients should be advised to avoid rising abruptly from a sitting or
recumbent position and to notify their physician if they experience dizziness,
lightheadedness, syncope, orthostasis, or tachycardia.
P D U T I B P H : P A W A S K A R R M
33
32. GENERIC:
MOA:
INDICATIONS:
CONTRAINDICATIONS:
ADVERSE EVENTS:
PREGNANCY:
PRECAUTIONS:
STD. DOSE:
P D U T I B P H : P A W A S K A R R M
35
Editor's Notes
Risk factors for PD:
Sleep cycle disturbances
Cognitive impairment
Antipsyhotics
Increased exposure to pesticides
Dose
dose
dose
dose
is a quaternary ammonium compound[1] involved in metabolism in most mammals, plants, and some bacteria. Carnitine is the generic expression for a number of compounds that include l-carnitine, acetyl-l-carnitine, and propionyl-l-carnitine. It is most accumulated in cardiac and skeletal muscles as it accounts for 0.1% of its dry matter. It was first derived from meat extracts in 1905, therefore the name carnitine is derived from Latin "carnus" or flesh. The body synthesizes enough carnitine from lysine side chains to keep up with the needs of energy production in the body as carnitine acts as a transporter of long-chain fatty acids into the mitochondria to be oxidized and produce energy. Some individuals with genetic or medical disorder
6.2Supplementation
6.3Male infertility
6.4Cardiovascular and peripheral arterial diseases
6.5Atherosclerosis
6.6Diabetes mellitus type 2
6.7AIDS and HIV
6.8End stage renal disease and hemodialysis