Pain is a common and often undertreated problem. Effective pain management is important as pain can have serious psychological and physical effects. It is also a basic human right. There are challenges to effective pain management, including conflicting views between patients and healthcare providers about reported pain levels and needed treatment. Proper use of the WHO analgesic ladder and comprehensive pain management regimens tailored to individual patients can help ensure patients' pain is adequately treated.
CME presentation made on 10th Nov 2012. Discusses a Radiation Oncologist's perspectives of cancer pain management, shortcomings of WHO pain ladder, ASTRO guidelines for metastatic bone pain.
CME presentation made on 10th Nov 2012. Discusses a Radiation Oncologist's perspectives of cancer pain management, shortcomings of WHO pain ladder, ASTRO guidelines for metastatic bone pain.
Chronic pain: Role of tricyclic antidepressants, dolsulepinSudhir Kumar
Chronic pain is common. Depression often co-exist with chronic pain. This article looks at the pathophysiology, prevalence of chronic pain and depression. The role of TCA, especially dosulepin and amitriptyline has been discussed.
12.04.08(a): Pathogenesis and Treatment of FibromyalgiaOpen.Michigan
Slideshow is from the University of Michigan Medical School's M2 Musculoskeletal sequence
View additional course materials on Open.Michigan:
openmi.ch/med-M2Muscu
Clossing
By 3 step ladder WHO cancer pain management, 90 % of cancer pain can be relief.
Since cancer patients cannot be cured, our main task is to let them die free of pain with Iman
my presentation provide how can we approach patient with chronic pain, when we suspect psychiatric cause for chronic pain any how we explain chronic psychogenic pain and how we manage.
Pain management strategies & effects on wellbeingmiranda olding
Overview of pain, common pain management strategies and their effects on wellbeing. Side effects, effects on wellbeing, Covers Pain cycle, Persistent or chronic pain, pain gate theory, pharmaceutical and non-pharmaceutical or pain treatments, including complementary therapies, electrotherapies, psychological therapies for pain.
Written for student OT conference 'Perspectives on Wellbeing' Feb 2016
Chronic pain: Role of tricyclic antidepressants, dolsulepinSudhir Kumar
Chronic pain is common. Depression often co-exist with chronic pain. This article looks at the pathophysiology, prevalence of chronic pain and depression. The role of TCA, especially dosulepin and amitriptyline has been discussed.
12.04.08(a): Pathogenesis and Treatment of FibromyalgiaOpen.Michigan
Slideshow is from the University of Michigan Medical School's M2 Musculoskeletal sequence
View additional course materials on Open.Michigan:
openmi.ch/med-M2Muscu
Clossing
By 3 step ladder WHO cancer pain management, 90 % of cancer pain can be relief.
Since cancer patients cannot be cured, our main task is to let them die free of pain with Iman
my presentation provide how can we approach patient with chronic pain, when we suspect psychiatric cause for chronic pain any how we explain chronic psychogenic pain and how we manage.
Pain management strategies & effects on wellbeingmiranda olding
Overview of pain, common pain management strategies and their effects on wellbeing. Side effects, effects on wellbeing, Covers Pain cycle, Persistent or chronic pain, pain gate theory, pharmaceutical and non-pharmaceutical or pain treatments, including complementary therapies, electrotherapies, psychological therapies for pain.
Written for student OT conference 'Perspectives on Wellbeing' Feb 2016
Recomendações da OMS sobre cuidados maternos e neonatais para uma experiência pós-natal positiva.
Em consonância com os ODS – Objetivos do Desenvolvimento Sustentável e a Estratégia Global para a Saúde das Mulheres, Crianças e Adolescentes, e aplicando uma abordagem baseada nos direitos humanos, os esforços de cuidados pós-natais devem expandir-se para além da cobertura e da simples sobrevivência, de modo a incluir cuidados de qualidade.
Estas diretrizes visam melhorar a qualidade dos cuidados pós-natais essenciais e de rotina prestados às mulheres e aos recém-nascidos, com o objetivo final de melhorar a saúde e o bem-estar materno e neonatal.
Uma “experiência pós-natal positiva” é um resultado importante para todas as mulheres que dão à luz e para os seus recém-nascidos, estabelecendo as bases para a melhoria da saúde e do bem-estar a curto e longo prazo. Uma experiência pós-natal positiva é definida como aquela em que as mulheres, pessoas que gestam, os recém-nascidos, os casais, os pais, os cuidadores e as famílias recebem informação consistente, garantia e apoio de profissionais de saúde motivados; e onde um sistema de saúde flexível e com recursos reconheça as necessidades das mulheres e dos bebês e respeite o seu contexto cultural.
Estas diretrizes consolidadas apresentam algumas recomendações novas e já bem fundamentadas sobre cuidados pós-natais de rotina para mulheres e neonatos que recebem cuidados no pós-parto em unidades de saúde ou na comunidade, independentemente dos recursos disponíveis.
É fornecido um conjunto abrangente de recomendações para cuidados durante o período puerperal, com ênfase nos cuidados essenciais que todas as mulheres e recém-nascidos devem receber, e com a devida atenção à qualidade dos cuidados; isto é, a entrega e a experiência do cuidado recebido. Estas diretrizes atualizam e ampliam as recomendações da OMS de 2014 sobre cuidados pós-natais da mãe e do recém-nascido e complementam as atuais diretrizes da OMS sobre a gestão de complicações pós-natais.
O estabelecimento da amamentação e o manejo das principais intercorrências é contemplada.
Recomendamos muito.
Vamos discutir essas recomendações no nosso curso de pós-graduação em Aleitamento no Instituto Ciclos.
Esta publicação só está disponível em inglês até o momento.
Prof. Marcus Renato de Carvalho
www.agostodourado.com
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
New Drug Discovery and Development .....NEHA GUPTA
The "New Drug Discovery and Development" process involves the identification, design, testing, and manufacturing of novel pharmaceutical compounds with the aim of introducing new and improved treatments for various medical conditions. This comprehensive endeavor encompasses various stages, including target identification, preclinical studies, clinical trials, regulatory approval, and post-market surveillance. It involves multidisciplinary collaboration among scientists, researchers, clinicians, regulatory experts, and pharmaceutical companies to bring innovative therapies to market and address unmet medical needs.
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
CDSCO and Phamacovigilance {Regulatory body in India}NEHA GUPTA
The Central Drugs Standard Control Organization (CDSCO) is India's national regulatory body for pharmaceuticals and medical devices. Operating under the Directorate General of Health Services, Ministry of Health & Family Welfare, Government of India, the CDSCO is responsible for approving new drugs, conducting clinical trials, setting standards for drugs, controlling the quality of imported drugs, and coordinating the activities of State Drug Control Organizations by providing expert advice.
Pharmacovigilance, on the other hand, is the science and activities related to the detection, assessment, understanding, and prevention of adverse effects or any other drug-related problems. The primary aim of pharmacovigilance is to ensure the safety and efficacy of medicines, thereby protecting public health.
In India, pharmacovigilance activities are monitored by the Pharmacovigilance Programme of India (PvPI), which works closely with CDSCO to collect, analyze, and act upon data regarding adverse drug reactions (ADRs). Together, they play a critical role in ensuring that the benefits of drugs outweigh their risks, maintaining high standards of patient safety, and promoting the rational use of medicines.
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
Knee anatomy and clinical tests 2024.pdfvimalpl1234
This includes all relevant anatomy and clinical tests compiled from standard textbooks, Campbell,netter etc..It is comprehensive and best suited for orthopaedicians and orthopaedic residents.
3. Pain relief; A basic human right
Pain is leading cause of ER visits and hospitalizations
Pain is a common mode of presentation in patients with
sickle cell disease (SCD) but there is considerable
variability in the way SCD pain is managed
4. Pain relief; A basic human right
Pain is common undertreated entity
One of the factors contributing to poor pain management is
conflicting perceptions between patients, their families and
healthcare professionals about pain that is reported and
analgesia that is required (Stinson & Naser, 2003).
5.
6. Pain relief; A basic human right
The most reliable indicator of the existence pain and its intensity
is the patient’s description
7. Pain relief; A basic human right
The aim of the wise is not to secure pleasure, but to
avoid pain. Aristotle
Pain is a worst lord of mankind than death itself.
8. Pain relief; A basic human right
Tachycardia And elevated blood pressure
Decreased Limb movement; increased risk of DVT
Respiratory effects; shallow breathing , tachypnea, cough suppression
. due to increased risk of pneumonia & atelectasis
Decreased GI Motility
Increased catabolic demands
9. Pain relief; A basic human right
Psychological effects of Pain
Negative emotions: anxiety, depression
Sleep deprivation
Existential suffering: may lead to patients
seeking active end of life
Immunologic Effects of pain
Decrease natural killer cell counts
Effects on other lymphocytes not yet defined
10. Pain relief; A basic human right
5TH Vital Sign
Basic human Right; Human rights watch
11. Pain relief; A basic human right
Effective control of pain
Lack of awareness among public
Minimal knowledge among health providers
13. Modified WHO Analgesic Ladder
Quality of Life
Invasive treatments
Proposed 4th Step Opioid Delivery
Pain persisting or increasing
Step 3
Opioid for moderate to severe pain
Nonopioid Adjuvant
Pain persisting or increasing
Step 2
Opioid for mild to moderate pain
The WHO Nonopioid Adjuvant
Ladder Pain persisting or increasing
Step 1
Nonopioid
Adjuvant
Pain
Deer, et al., 1999
19. Pain relief; A basic human right
Table: Severity of pain (Using a simple pain score)
.
0
Mafee alam No Pain
1
Shoa alam Mild Pain
2
Nus nus alam Moderate pain
3
Kateer alam) Severe Pain
20. Acute Pain in Sickle Cell Disease
Somatic pain
– Deep structures
– Focal or referred
Visceral pain
– Spleen, liver, lungs
– Vague, poorly localized, referred, diffuse, dull-aching in character
– Nausea, vomiting, sweating
– Associated with muscle spasms, tenderness, hyperaesthesia
21. Comprehensive Regimen for the sickle cell disease pain
Maintenance therapy with opioid analgesic
Non opioid analgesic
Rescue therapy for breakthrough pain
Adjuvant therapy
Anxiolytics/muscle relaxants
Laxatives
Non-pharmacologic therapy
Incentive spirometry
Hydration (1-1.5x maintenance)
Physical: Heating pads, massage, TENS, acupuncture, physical therapy
Behavioral: Relaxation, deep breathing, behavior modification, biofeedback
•Psychological: cognitive therapies, distraction, social support, hypnotherapy
23. Meperidine
Shorter duration of action (1-2 hours only )
Seizures on repeated administration
Dermal and sub dermal fibrosis on I.M injection
Pethidine
Narrow therapeutic index
Norpethidine > Antagonistic
Seizures on repeated administration
25. Pain relief; A basic human right
S.No Severity of pain Regimen
1 Mild Paracetomol 0.5g to 1g every 8H /
Lornoxicam4-8 mg Every 12-24 H
2 Moderate Paracetomol 0.5g to 1g every 8H /
Lornoxicam4-8 mg Every 12-24 H
+
Tramadol50-100mgs Q 8H
3 Severe Paracetomol 0.5g to 1g every 8H /
Lornoxicam4-8 mg Every 12-24 H
+
Morphine 5-mgs Q 8 H
26. Pain relief; A basic human right
PRN Schedule Illogical
Pain Cycle (Basal + Incident + Breakthrough Pain
Start (1Hr)} Asses} Reassess} Adjust
Tapering and not abrupt withdrawl
27. Pain relief; A basic human right
NSAIDS
Bone Pain
Opiod Sparing
Ceiling Effect
Opiods
Potent analgesics
Safety Profile
28. Pain relief; A basic human right
Addiction
Nightmare for physician
Curse for the patient
29. Pain relief; A basic human right
When asked, 59% of the patients desired that oral non-
opioid analgesics be prescribed while 31% were not
bothered about what analgesic was given. Only 8%
requested opioids.
A total of 65% of the patients did not require hospital
admission but were observed in the day-care unit and
allowed home within 24 h. Only 17% required hospital
admission for more than a week.
30. Pain relief; A basic human right
Prevention of Pain
Triggers of pain: viral illness,
infection/sepsis, stress, extreme exercise,
change in temperature, change in altitude
Fluids (2 glasses of water q 2 hours)
Avoiding extreme temperatures, activities (e.g. swimming in cold
water)
Regular moderate exercise
Penicillin prophylaxis to prevent infection