In common parlance; the imminent universal process of NAMASMARAN and realizing the true SELF; by billions; and the holistic renaissance - the individual and universal blossoming - a changing contingent without a regimentalized uniform pattern; is the will of God!
Rudra Homam
Rudra homam is a capable homam or flame custom for purifying the arrangement of all profound established issue.
Rudram conists of 11 chapters (Anuvakams) of Namakam and Camakam. Namakam extols the divine light of creator reflected in the creation. Perform Rudra Series of Homam
From your Home - Vedicfolks offers : http://www.vedicfolks.com/rudra-homam.html
Tejaswi Drushti Bestseller For Super Eyesight Dr. Shriniwas Kashalikarsrinishriya
Dr. Shriniwas Janardan Kashalikar's new; empowering and enlightening experiences; and inspiring insights; based on study of Gita, Vishnusahasranam, Namasmaran and life; for individual and global blossoming!
Vyasan Mukti Bestseller For Deaddiction Dr. Shriniwas Kashalikarsrinishriya
Dr. Shriniwas Janardan Kashalikar's new; empowering and enlightening experiences; and inspiring insights; based on study of Gita, Vishnusahasranam, Namasmaran and life; for individual and global blossoming!
In common parlance; the imminent universal process of NAMASMARAN and realizing the true SELF; by billions; and the holistic renaissance - the individual and universal blossoming - a changing contingent without a regimentalized uniform pattern; is the will of God!
Rudra Homam
Rudra homam is a capable homam or flame custom for purifying the arrangement of all profound established issue.
Rudram conists of 11 chapters (Anuvakams) of Namakam and Camakam. Namakam extols the divine light of creator reflected in the creation. Perform Rudra Series of Homam
From your Home - Vedicfolks offers : http://www.vedicfolks.com/rudra-homam.html
Tejaswi Drushti Bestseller For Super Eyesight Dr. Shriniwas Kashalikarsrinishriya
Dr. Shriniwas Janardan Kashalikar's new; empowering and enlightening experiences; and inspiring insights; based on study of Gita, Vishnusahasranam, Namasmaran and life; for individual and global blossoming!
Vyasan Mukti Bestseller For Deaddiction Dr. Shriniwas Kashalikarsrinishriya
Dr. Shriniwas Janardan Kashalikar's new; empowering and enlightening experiences; and inspiring insights; based on study of Gita, Vishnusahasranam, Namasmaran and life; for individual and global blossoming!
Swacchata Marathi Bestseller Dr. Shriniwas Kashalikarsrinishriya
Dr. Shriniwas Janardan Kashalikar's new; empowering and enlightening experiences; and inspiring insights; based on study of Gita, Vishnusahasranam, Namasmaran and life; for individual and global blossoming!
Indian Medical Advisors Summit 2014 HighlightsAnup Soans
INMAS - Indian Medical Advisors Summit is first of its kind initiative that has been
undertaken in India for the cause of Medical Affairs.
INMAS - Indian Medical Advisors Summit - 2014 - Watch Video on
www.youtube.com - https://www.youtube.com/watch?v=vCNVUlzyEpg
For a moderately complex application to manage complexity it needs to be broken up into smaller modules – which can be developed / tested independently. The modularization should be based on the domain rather than along layers (dao/service etc). This session will focus on some guidelines on how to breakup large applications into modules and how to realize that modularity in an application that uses Spring, Hibernate, Maven. The talk is based on the experience gained implementing (and refining) these techniques in 3-4 large product development that I have been involved in.
Why KAM Fails in Pharma, Job Satisfaction Survey Results. Pharma Rural Marketing. Coaching in Pharma. 9 Simple Steps to Better Team Management. Basics of Pharmacology for Medical Reps and more
Current State of Affairs – Cloud Computing - Indicthreads Cloud Computing Con...IndicThreads
Session presented at the 2nd IndicThreads.com Conference on Cloud Computing held in Pune, India on 3-4 June 2011.
http://CloudComputing.IndicThreads.com
Abstract: Cloud Computing has had phenomenal growth over the past year and continues to entrench itself in all facets of IT. Cloud Computing is definitely more than just a buzz word or a passing trend. Now the heavy weights like IBM, HP and SAP are ready lock horns with existing players like Amazon, Salesforce and Microsoft whose offerings have matured over a period of time. Besides these big players, a lot of start ups are coming up with innovative offerings in this space.
The talk is about the current state of affairs in the cloud computing. It will cover the products, services and offerings that have been making a lot of noise in the cloud computing space.
Following are the main points that will be covered in the talk:
1. New Players: A lot of enterprise market giants are now coming to the cloud party offering infrastructure and platform services. IBM has come out with its SmartCloud for private as well as public clouds. Oracle has released its Cloud-in-a-box solution. The talk will cover all the new offerings by these enterprise giants.
2. Old Players, New offerings – Amazon being the leader in the Cloud Infrastructure space has rolled out a lot of new products and services, strengthening its hold in the market and expanding into the PaaS segment. Amazon Beanstalk, Amazon CloudFormation and EC2 Dedicated instances most notably have the power to be game changers. SalesForce the leader in the Cloud SaaS space released database.com, enterprise cloud database and its “PaaS” offering similar to GAE – VMforce.com This section will cover the new offerings by the players.
3 .Interesting Players in the cloud ecosystem: There have been a lot of new players who are leveraging the cloud to build some exciting products like Scalable API platforms, Cloud-based logging, Java in the Cloud. etc eg. Apigee, PiCloud, Loggly,Cumulogic, Cloudbees being some of them. This section will cover most of the exciting platforms and technologies these companies are working on.
4. Current Trends and Future: This section will cover the current trends(where a lot of startups are investing in) and how the future will look like in the cloud space.
Finally, the talk plans to “arm” developers and architects with the latest and cutting edge platforms, products and technologies in the cloud that have been developed and made available over the last year, helping them to leverage the cloud and make better choices leading to higher ROI and lesser TCO.
Speaker:
Chirag Jog, is the CTO at Clogeny Technologies where the main focus is on Innovation in the Cloud Computing, Scalable Applications and Storage space. He is the chief geek at Clogeny who talks “Cloud” and works on architecting exciting ideas in the cloud space. He has previously spoken at IndicThreads, CloudCamp and other cloud related events.
ePortfolios for Adults and Other Humans (rev 2014)Don Presant
An exploration of how ePortfolios can help support and demonstrate the learning of adults.
Revised from the original presentation in 2013 to include a description of a new shared ePortfolio service for educators and trainers called savvyfolio.net.
This is a compilation of articles, which unravel the composite individual and social blossoming; implicit in the culmination of psychological, social, philosophical and scientific pursuits; embodied in NAMASMARAN.
It is said that NAMASMARAN can influence the social life, because the blossoming of an individual is irresistibly manifested in society; impossible to be ignored. There are many illustrious examples such as scholarly saints Dnyaneshvar, Tulsidas, Tukaram, Samarth Ramadas, Eknath, Namadev, Meera, Kabir, Chaitanya Mahaprabhu; including Acharya Vinoba Bhave, Mahatma Gandhi and Brahmachaitanya Shri Gondavalekar Maharaj.
LIVE IN HAPPINESS AND ENJOY PLEASURES- THE ANCIENT FORMULA Dr. Raju M. Mathew
Men and women who cannot enjoy Food, Sleep and Sex are always Unhappy and making others life miserable; some of them bring War and Terror. The inability of men or women to enjoy them leads them to Religious Fundamentalism, Terror and War. Yet others substitute their inability with Money, Power or Fame.
No religion or Ideology has any formula or secret key to live in Happiness and Enjoy Pleasures of Life and Living in Happiness .Islam, Christianity, Capitalism and Communism make life miserable without Happiness and Enjoying Pleasures either for Heaven or Paradise after death or the New Earth and Heaven, after class war. Islam, Christianity, Capitalism and Communism have a history of 2000 years or less. On the other hand the Ancient Wisdom help us Live in Happiness and Enjoy Pleasures of Life without which life is incomplete and imbalanced. Men and Women have Mind and Soul besides Body. If there is no proper integration between them, no man or woman can enjoy Food, Sleep and Sex. Without such simple and basic Pleasures, nobody can live in Happiness. Unfortunately over 90% of the men and women could not enjoy these three vital things in life for the Disintegrated Mind, Disintegrated Body and Imprisoned Soul. The Ancient Wisdom is the Key for Happiness and Pleasures.
The Wisdom of Ancient India helps us find out the Secret Formula to solve this problem. It provides answers for most of the complex problems faced by the Modern Man or World, including Religions and Nations. This presentation helps to develop a clear understanding of the Ancient Indian Wisdom and thereby finding out Solutions for most of the present day problems of Peace and Prosperity. It is helpful not only the rulers and managers but also the common people.
NAMASMARAN; the return from narrow self to universal self; as described in this best seller; by Dr. Shriniwas Kashalikar; is an objective mega process of conscious evolutionary transformation of all!
Do we have the team spirit, conviction of relevance and optimum efficiency in performing the "task" of sharing the benevolence of NAMASMARAN (JIKRA, JAAP, JAP, SUMIRAN, SIMARAN, REMEMBERING TRUE SELF)?
NAMASMARAN; the return from narrow self to universal self; as described in this best seller; by Dr. Shriniwas Kashalikar; is an objective mega process of conscious evolutionary transformation of all!
But enlightenment and empowerment of the Total Stress Management (the core of which is NAMASMARAN); are not confined to mere socioeconomic progress of the world. They go far beyond. They become truly sublime. They transcend space and time to go on invigorating and blossoming billions after billions for millennia.
Swacchata Marathi Bestseller Dr. Shriniwas Kashalikarsrinishriya
Dr. Shriniwas Janardan Kashalikar's new; empowering and enlightening experiences; and inspiring insights; based on study of Gita, Vishnusahasranam, Namasmaran and life; for individual and global blossoming!
Indian Medical Advisors Summit 2014 HighlightsAnup Soans
INMAS - Indian Medical Advisors Summit is first of its kind initiative that has been
undertaken in India for the cause of Medical Affairs.
INMAS - Indian Medical Advisors Summit - 2014 - Watch Video on
www.youtube.com - https://www.youtube.com/watch?v=vCNVUlzyEpg
For a moderately complex application to manage complexity it needs to be broken up into smaller modules – which can be developed / tested independently. The modularization should be based on the domain rather than along layers (dao/service etc). This session will focus on some guidelines on how to breakup large applications into modules and how to realize that modularity in an application that uses Spring, Hibernate, Maven. The talk is based on the experience gained implementing (and refining) these techniques in 3-4 large product development that I have been involved in.
Why KAM Fails in Pharma, Job Satisfaction Survey Results. Pharma Rural Marketing. Coaching in Pharma. 9 Simple Steps to Better Team Management. Basics of Pharmacology for Medical Reps and more
Current State of Affairs – Cloud Computing - Indicthreads Cloud Computing Con...IndicThreads
Session presented at the 2nd IndicThreads.com Conference on Cloud Computing held in Pune, India on 3-4 June 2011.
http://CloudComputing.IndicThreads.com
Abstract: Cloud Computing has had phenomenal growth over the past year and continues to entrench itself in all facets of IT. Cloud Computing is definitely more than just a buzz word or a passing trend. Now the heavy weights like IBM, HP and SAP are ready lock horns with existing players like Amazon, Salesforce and Microsoft whose offerings have matured over a period of time. Besides these big players, a lot of start ups are coming up with innovative offerings in this space.
The talk is about the current state of affairs in the cloud computing. It will cover the products, services and offerings that have been making a lot of noise in the cloud computing space.
Following are the main points that will be covered in the talk:
1. New Players: A lot of enterprise market giants are now coming to the cloud party offering infrastructure and platform services. IBM has come out with its SmartCloud for private as well as public clouds. Oracle has released its Cloud-in-a-box solution. The talk will cover all the new offerings by these enterprise giants.
2. Old Players, New offerings – Amazon being the leader in the Cloud Infrastructure space has rolled out a lot of new products and services, strengthening its hold in the market and expanding into the PaaS segment. Amazon Beanstalk, Amazon CloudFormation and EC2 Dedicated instances most notably have the power to be game changers. SalesForce the leader in the Cloud SaaS space released database.com, enterprise cloud database and its “PaaS” offering similar to GAE – VMforce.com This section will cover the new offerings by the players.
3 .Interesting Players in the cloud ecosystem: There have been a lot of new players who are leveraging the cloud to build some exciting products like Scalable API platforms, Cloud-based logging, Java in the Cloud. etc eg. Apigee, PiCloud, Loggly,Cumulogic, Cloudbees being some of them. This section will cover most of the exciting platforms and technologies these companies are working on.
4. Current Trends and Future: This section will cover the current trends(where a lot of startups are investing in) and how the future will look like in the cloud space.
Finally, the talk plans to “arm” developers and architects with the latest and cutting edge platforms, products and technologies in the cloud that have been developed and made available over the last year, helping them to leverage the cloud and make better choices leading to higher ROI and lesser TCO.
Speaker:
Chirag Jog, is the CTO at Clogeny Technologies where the main focus is on Innovation in the Cloud Computing, Scalable Applications and Storage space. He is the chief geek at Clogeny who talks “Cloud” and works on architecting exciting ideas in the cloud space. He has previously spoken at IndicThreads, CloudCamp and other cloud related events.
ePortfolios for Adults and Other Humans (rev 2014)Don Presant
An exploration of how ePortfolios can help support and demonstrate the learning of adults.
Revised from the original presentation in 2013 to include a description of a new shared ePortfolio service for educators and trainers called savvyfolio.net.
This is a compilation of articles, which unravel the composite individual and social blossoming; implicit in the culmination of psychological, social, philosophical and scientific pursuits; embodied in NAMASMARAN.
It is said that NAMASMARAN can influence the social life, because the blossoming of an individual is irresistibly manifested in society; impossible to be ignored. There are many illustrious examples such as scholarly saints Dnyaneshvar, Tulsidas, Tukaram, Samarth Ramadas, Eknath, Namadev, Meera, Kabir, Chaitanya Mahaprabhu; including Acharya Vinoba Bhave, Mahatma Gandhi and Brahmachaitanya Shri Gondavalekar Maharaj.
LIVE IN HAPPINESS AND ENJOY PLEASURES- THE ANCIENT FORMULA Dr. Raju M. Mathew
Men and women who cannot enjoy Food, Sleep and Sex are always Unhappy and making others life miserable; some of them bring War and Terror. The inability of men or women to enjoy them leads them to Religious Fundamentalism, Terror and War. Yet others substitute their inability with Money, Power or Fame.
No religion or Ideology has any formula or secret key to live in Happiness and Enjoy Pleasures of Life and Living in Happiness .Islam, Christianity, Capitalism and Communism make life miserable without Happiness and Enjoying Pleasures either for Heaven or Paradise after death or the New Earth and Heaven, after class war. Islam, Christianity, Capitalism and Communism have a history of 2000 years or less. On the other hand the Ancient Wisdom help us Live in Happiness and Enjoy Pleasures of Life without which life is incomplete and imbalanced. Men and Women have Mind and Soul besides Body. If there is no proper integration between them, no man or woman can enjoy Food, Sleep and Sex. Without such simple and basic Pleasures, nobody can live in Happiness. Unfortunately over 90% of the men and women could not enjoy these three vital things in life for the Disintegrated Mind, Disintegrated Body and Imprisoned Soul. The Ancient Wisdom is the Key for Happiness and Pleasures.
The Wisdom of Ancient India helps us find out the Secret Formula to solve this problem. It provides answers for most of the complex problems faced by the Modern Man or World, including Religions and Nations. This presentation helps to develop a clear understanding of the Ancient Indian Wisdom and thereby finding out Solutions for most of the present day problems of Peace and Prosperity. It is helpful not only the rulers and managers but also the common people.
NAMASMARAN; the return from narrow self to universal self; as described in this best seller; by Dr. Shriniwas Kashalikar; is an objective mega process of conscious evolutionary transformation of all!
Do we have the team spirit, conviction of relevance and optimum efficiency in performing the "task" of sharing the benevolence of NAMASMARAN (JIKRA, JAAP, JAP, SUMIRAN, SIMARAN, REMEMBERING TRUE SELF)?
NAMASMARAN; the return from narrow self to universal self; as described in this best seller; by Dr. Shriniwas Kashalikar; is an objective mega process of conscious evolutionary transformation of all!
But enlightenment and empowerment of the Total Stress Management (the core of which is NAMASMARAN); are not confined to mere socioeconomic progress of the world. They go far beyond. They become truly sublime. They transcend space and time to go on invigorating and blossoming billions after billions for millennia.
. Namasmaran; by virtue of its almost universal acceptability, simplicity, non-technicality and inexpensiveness has the potential to be beneficial in stress management, to majority of people in the world, irrespective of age, sex, occupation, socioeconomic stratum, race, religion, culture, ideology, nationality.
NAMASMARAN; the return from narrow self to universal self; as described in this best seller; by Dr. Shriniwas Kashalikar; is an objective mega process of conscious evolutionary transformation of all!
NAME, NAMASMARAN and TOTAL STRESS MANAGEMENT: The concept of the title is; NAMA is the absolute truth beyond time and space. It is the ultimate controlling center. NAMASMARAN is the product of NAMA; and TOTAL STRESS MANAGEMENT is the effect of NAMASMARAN.
Attaining Happiness and Enjoying Pleasures - The Indian Wisdom and Formula.Dr. Raju M. Mathew
Life is meaningless without enjoying Happiness and Pleasures in a Harmonious and Balanced Way. Without Happiness and Pleasures, there is no meaning for any Gain or Achievement or Beauty or Fashion. How to enjoy Life on Earth is the basic question explored in this presentation.
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
Explore natural remedies for syphilis treatment in Singapore. Discover alternative therapies, herbal remedies, and lifestyle changes that may complement conventional treatments. Learn about holistic approaches to managing syphilis symptoms and supporting overall health.
Recomendações da OMS sobre cuidados maternos e neonatais para uma experiência pós-natal positiva.
Em consonância com os ODS – Objetivos do Desenvolvimento Sustentável e a Estratégia Global para a Saúde das Mulheres, Crianças e Adolescentes, e aplicando uma abordagem baseada nos direitos humanos, os esforços de cuidados pós-natais devem expandir-se para além da cobertura e da simples sobrevivência, de modo a incluir cuidados de qualidade.
Estas diretrizes visam melhorar a qualidade dos cuidados pós-natais essenciais e de rotina prestados às mulheres e aos recém-nascidos, com o objetivo final de melhorar a saúde e o bem-estar materno e neonatal.
Uma “experiência pós-natal positiva” é um resultado importante para todas as mulheres que dão à luz e para os seus recém-nascidos, estabelecendo as bases para a melhoria da saúde e do bem-estar a curto e longo prazo. Uma experiência pós-natal positiva é definida como aquela em que as mulheres, pessoas que gestam, os recém-nascidos, os casais, os pais, os cuidadores e as famílias recebem informação consistente, garantia e apoio de profissionais de saúde motivados; e onde um sistema de saúde flexível e com recursos reconheça as necessidades das mulheres e dos bebês e respeite o seu contexto cultural.
Estas diretrizes consolidadas apresentam algumas recomendações novas e já bem fundamentadas sobre cuidados pós-natais de rotina para mulheres e neonatos que recebem cuidados no pós-parto em unidades de saúde ou na comunidade, independentemente dos recursos disponíveis.
É fornecido um conjunto abrangente de recomendações para cuidados durante o período puerperal, com ênfase nos cuidados essenciais que todas as mulheres e recém-nascidos devem receber, e com a devida atenção à qualidade dos cuidados; isto é, a entrega e a experiência do cuidado recebido. Estas diretrizes atualizam e ampliam as recomendações da OMS de 2014 sobre cuidados pós-natais da mãe e do recém-nascido e complementam as atuais diretrizes da OMS sobre a gestão de complicações pós-natais.
O estabelecimento da amamentação e o manejo das principais intercorrências é contemplada.
Recomendamos muito.
Vamos discutir essas recomendações no nosso curso de pós-graduação em Aleitamento no Instituto Ciclos.
Esta publicação só está disponível em inglês até o momento.
Prof. Marcus Renato de Carvalho
www.agostodourado.com
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
Adv. biopharm. APPLICATION OF PHARMACOKINETICS : TARGETED DRUG DELIVERY SYSTEMSAkankshaAshtankar
MIP 201T & MPH 202T
ADVANCED BIOPHARMACEUTICS & PHARMACOKINETICS : UNIT 5
APPLICATION OF PHARMACOKINETICS : TARGETED DRUG DELIVERY SYSTEMS By - AKANKSHA ASHTANKAR
2. PRAYENA DEVA MUNAYAH
SWAVIMUKTIKAMA
MAUNAM CHARANTI VIJANENA
PARARTHA NISHTHA
NAITANVIHAYA KRUPANAN
SWAVIMUKTI EKO
NANYAM TADASYA SHARANAM
BHRAMATONUPASHYE
Oh Lord, in general, most of the great saints,
sages, yogis and rishis renounce the world, live
in seclusion and observe silence in search of
salvation/liberation for themselves.
Since you are the only savior for my billions of
brothers and since they can not get salvation
from anywhere else [in case I do not seek it
from you for them],
3. I do not want to be a mean person to seek
liberation for myself alone.
So says the great Pralhada as is articulated in
SHRIMAT BHAGAVATAM.
This is especially important in view of the
fact that though stress [and hence
conceptual stress also] is a universal
phenomenon, it is not understood by all!
Only a few fortunate ones would be able to
understand and manage it. It is their
privilege and DHARMA to help others in
managing stress. In this regard it is
interesting to note that in these days neither
individual liberation nor individual stress
management are possible! They are
intricately and inseparably bound with the
liberation and stress management of billions
others!
4. Bhagiratha [who is said to have brought the
river Ganga from heaven to the earth] and
Prometheus [who is said to have stolen fire
from the gods] to save the mankind and
many others have set examples for us to
follow.
DR.
SHRINIWAS
KASHALIKAR