Tejaswi Drushti Bestseller For Super Eyesight Dr. Shriniwas Kashalikarsrinishriya
Dr. Shriniwas Janardan Kashalikar's new; empowering and enlightening experiences; and inspiring insights; based on study of Gita, Vishnusahasranam, Namasmaran and life; for individual and global blossoming!
Vyasan Mukti Bestseller For Deaddiction Dr. Shriniwas Kashalikarsrinishriya
Dr. Shriniwas Janardan Kashalikar's new; empowering and enlightening experiences; and inspiring insights; based on study of Gita, Vishnusahasranam, Namasmaran and life; for individual and global blossoming!
Tejaswi Drushti Bestseller For Super Eyesight Dr. Shriniwas Kashalikarsrinishriya
Dr. Shriniwas Janardan Kashalikar's new; empowering and enlightening experiences; and inspiring insights; based on study of Gita, Vishnusahasranam, Namasmaran and life; for individual and global blossoming!
Vyasan Mukti Bestseller For Deaddiction Dr. Shriniwas Kashalikarsrinishriya
Dr. Shriniwas Janardan Kashalikar's new; empowering and enlightening experiences; and inspiring insights; based on study of Gita, Vishnusahasranam, Namasmaran and life; for individual and global blossoming!
Swacchata Marathi Bestseller Dr. Shriniwas Kashalikarsrinishriya
Dr. Shriniwas Janardan Kashalikar's new; empowering and enlightening experiences; and inspiring insights; based on study of Gita, Vishnusahasranam, Namasmaran and life; for individual and global blossoming!
Front-line Manager is the Fulcrum of Field Force Excellence by K. Hariram. Emerging Trends and the Future of Pharma Field Force by Salil Kallianpur. Will the iPad Enable SFE? by Dr. Neelesh Bhandari and Many more articles that foster Field Force Excellence.
Many of the testers understand the importance of automated tests which can test the system end to end. There are plenty of tools like Selenium, Watir, White etc. which allow you to drive your web or desktop ui for these tests. The intention of these tests is to mimic the user’s interaction with the system and automatically validate that he could achieve his goals.
Considering this, wouldnt it make sense for tests to talk the same language that an end user understands. Although, When we look around today most of the functional tests talk the language that the browser understands, it goes click button A, enter value in textfield B etc.
In this session we will share various approaches which allow you to build tests which an end user can understand and maybe even participate in writing. We will look at the problems with the usual approach of end-to-end writing tests such as being too verbose and technical.
We will look at the multiple benefits of writing tests in the end user’s language and the different ways in which to achieve it.
Finally, we will look at the key takeaways.
The use of an electronic ILP (e-ILP) has a number of advantages for Colleges that are on split sites, or for programmes where the students cross a number of organisational and curriculum boundaries e.g. A Levels. The e-ILP is held centrally and viewed locally. These are screen shots from a system being developed at Peterborough.
Swacchata Marathi Bestseller Dr. Shriniwas Kashalikarsrinishriya
Dr. Shriniwas Janardan Kashalikar's new; empowering and enlightening experiences; and inspiring insights; based on study of Gita, Vishnusahasranam, Namasmaran and life; for individual and global blossoming!
Front-line Manager is the Fulcrum of Field Force Excellence by K. Hariram. Emerging Trends and the Future of Pharma Field Force by Salil Kallianpur. Will the iPad Enable SFE? by Dr. Neelesh Bhandari and Many more articles that foster Field Force Excellence.
Many of the testers understand the importance of automated tests which can test the system end to end. There are plenty of tools like Selenium, Watir, White etc. which allow you to drive your web or desktop ui for these tests. The intention of these tests is to mimic the user’s interaction with the system and automatically validate that he could achieve his goals.
Considering this, wouldnt it make sense for tests to talk the same language that an end user understands. Although, When we look around today most of the functional tests talk the language that the browser understands, it goes click button A, enter value in textfield B etc.
In this session we will share various approaches which allow you to build tests which an end user can understand and maybe even participate in writing. We will look at the problems with the usual approach of end-to-end writing tests such as being too verbose and technical.
We will look at the multiple benefits of writing tests in the end user’s language and the different ways in which to achieve it.
Finally, we will look at the key takeaways.
The use of an electronic ILP (e-ILP) has a number of advantages for Colleges that are on split sites, or for programmes where the students cross a number of organisational and curriculum boundaries e.g. A Levels. The e-ILP is held centrally and viewed locally. These are screen shots from a system being developed at Peterborough.
NVBDCP.pptx Nation vector borne disease control programSapna Thakur
NVBDCP was launched in 2003-2004 . Vector-Borne Disease: Disease that results from an infection transmitted to humans and other animals by blood-feeding arthropods, such as mosquitoes, ticks, and fleas. Examples of vector-borne diseases include Dengue fever, West Nile Virus, Lyme disease, and malaria.
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
New Drug Discovery and Development .....NEHA GUPTA
The "New Drug Discovery and Development" process involves the identification, design, testing, and manufacturing of novel pharmaceutical compounds with the aim of introducing new and improved treatments for various medical conditions. This comprehensive endeavor encompasses various stages, including target identification, preclinical studies, clinical trials, regulatory approval, and post-market surveillance. It involves multidisciplinary collaboration among scientists, researchers, clinicians, regulatory experts, and pharmaceutical companies to bring innovative therapies to market and address unmet medical needs.
Knee anatomy and clinical tests 2024.pdfvimalpl1234
This includes all relevant anatomy and clinical tests compiled from standard textbooks, Campbell,netter etc..It is comprehensive and best suited for orthopaedicians and orthopaedic residents.
CDSCO and Phamacovigilance {Regulatory body in India}NEHA GUPTA
The Central Drugs Standard Control Organization (CDSCO) is India's national regulatory body for pharmaceuticals and medical devices. Operating under the Directorate General of Health Services, Ministry of Health & Family Welfare, Government of India, the CDSCO is responsible for approving new drugs, conducting clinical trials, setting standards for drugs, controlling the quality of imported drugs, and coordinating the activities of State Drug Control Organizations by providing expert advice.
Pharmacovigilance, on the other hand, is the science and activities related to the detection, assessment, understanding, and prevention of adverse effects or any other drug-related problems. The primary aim of pharmacovigilance is to ensure the safety and efficacy of medicines, thereby protecting public health.
In India, pharmacovigilance activities are monitored by the Pharmacovigilance Programme of India (PvPI), which works closely with CDSCO to collect, analyze, and act upon data regarding adverse drug reactions (ADRs). Together, they play a critical role in ensuring that the benefits of drugs outweigh their risks, maintaining high standards of patient safety, and promoting the rational use of medicines.
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
Basavarajeeyam is a Sreshta Sangraha grantha (Compiled book ), written by Neelkanta kotturu Basavaraja Virachita. It contains 25 Prakaranas, First 24 Chapters related to Rogas& 25th to Rasadravyas.
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
2. NAMASKAR
Following are some protective
measures, which I feel can help. If
you agree, you may kindly share
them with your contacts.
1. NAMASMARAN
2. DINKING WATER IN MORNING
AND THROUGH OUT THE DAY
3. EATING TWO LEAVES OF
NEEM, TULASI, BEL EACH
4. CHYAVANAPRASH 1 TEA
SPOONFUL DAILY
5. DRINKING A CUP OF COW MILK
WITH TURMERIC (HALAD), DRY
GINGER (SUNTH) AND HONEY
6. PRACTICE OF KAPALBHATI
(ACTIVE ABDOMINAL
EXPIRATION WITHOUT
DISCOMFORT). Make sure you
3. don't have trauma, surgery, hernia
of any kind and pregnancy and
any other wound on abdominal or
related regions.
7. TAKING BATH TWICE A DAY.
8. CHANGING CLOTHES TWICE A
DAY
9. APPLYING A DROP OF COW
GHEE OR ANU TAIL IN BOTH
NOSTRILS
10. Take a capsule of multivitamin
capsue such as Becadexamin and
Bcomplex such as Becosule.
11. Wash hands fequently
(Suggested by Dr. Alka Halbe)
12. Avoid lifts (elevators) if and
when possible
13. Avoid excessively crowded
and/or centrally airconditioned
places such as railway stations,
cinema halls, theatres, malls.
4. 14. Consume juice of aloe vera
(korphad i.e. kumari) and
tinospora cordifolia (giloy or
gulvel i.e. guduchi) in addition to
holy basil, neem and bel. Promote
planting of these medicinal herbs.
15. Add jaggery, pepper (kali
mirch) and ginger in your tea (if
and when you take it)
For additional details you may
refer my books and articles
available for free download on
www.scribd.com/superliving.
Best wishes and warm regards.
Dr. Shriniwas Kashalikar
