The document discusses outcomes in rheumatoid arthritis (RA) including disease activity, disability, damage, and mortality. Specific factors related to poor outcomes include severe disease, involvement of many joints, rheumatoid factor positivity, and high inflammatory markers. Disease activity states refer to when RA is active with inflammation or inactive without it. Treatment goals aim to reduce severity, improve disability, stop joint damage, and avoid adverse events. Clinical measures, patient reports, laboratory tests, and radiological assessments are used to evaluate disease activity and outcomes.