Antenatal diagnosis of Congenital Anomalies of Kidneys and Urinary Tract (CAKUT)Durre Sabih
Antenatal Diagnosis of Kidney Disease. This presentation gives an overview of the role of ultrasound in the diagnosis of fetal renal disease and congenital renal anomalies
Antenatal diagnosis of Congenital Anomalies of Kidneys and Urinary Tract (CAKUT)Durre Sabih
Antenatal Diagnosis of Kidney Disease. This presentation gives an overview of the role of ultrasound in the diagnosis of fetal renal disease and congenital renal anomalies
this power point presentation is made ideally according to criteria of ppt. with opener , energizes , bibliography ans much more criteria are followed.thank you..
Urinary system – common pathological correlationKochi Chia
Presentation on common urinary system pathologies and radiological findings. Just a brief explanation. Further info can be obtained from www.radiopaedia.org and www.radiologyassistant.nl
continuation on the urinary tract disorders. congenital and acquired disorders well covered. pyelonephritis also forms part of the text. thanks for reading. remeber to like and follow
this power point presentation is made ideally according to criteria of ppt. with opener , energizes , bibliography ans much more criteria are followed.thank you..
Urinary system – common pathological correlationKochi Chia
Presentation on common urinary system pathologies and radiological findings. Just a brief explanation. Further info can be obtained from www.radiopaedia.org and www.radiologyassistant.nl
continuation on the urinary tract disorders. congenital and acquired disorders well covered. pyelonephritis also forms part of the text. thanks for reading. remeber to like and follow
Acute scrotum is a general term referring to an emergency condition affecting the contents or the wall of the scrotum.
There are a number of conditions that present acutely, predominantly with pain and/or swelling
A careful and detailed history and examination, and in some cases, investigations allow differentiation between these diagnoses. A prompt diagnosis is essential as the patient may require urgent surgical intervention
Testicular torsion refers to twisting of the spermatic cord, causing ischaemia of the testicle.
Testicular torsion results from inadequate fixation of the testis to the tunica vaginalis producing ischemia from reduced arterial inflow and venous outflow obstruction.
The prevalence of testicular torsion in adult patients hospitalized with acute scrotal pain is approximately 25 to 50 percent
These lecture slides, by Dr Sidra Arshad, offer a quick overview of physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar leads (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
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Couples presenting to the infertility clinic- Do they really have infertility...Sujoy Dasgupta
Dr Sujoy Dasgupta presented the study on "Couples presenting to the infertility clinic- Do they really have infertility? – The unexplored stories of non-consummation" in the 13th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE 2024) at Manila on 24 May, 2024.
3. Antenatal hydronephrosis
• It is identified in 1-3 % of all pregnancies.
• APD of the renal pelvis more than 5 mm.
• Measurement of the APD has been used widely.
• The APD can be affected by gestational age, hydration status of the mother, bladder
hypertonicity, and degree of bladder distention.
• The APD fails to describe pelvic configuration, calyceal dilation, and the laterality of findings.
4. Diagnostic Accuracy
• The risk of VUR per degree of ANH is similar, implying that ANH is not
an appropriate indicator of VUR.
• Obstruction may be diagnosed prenatally in 88%.
5.
6.
7.
8. Kidney
• Number, location, size, duplication, renal parenchyma, pelvic dilation,
calyceal dilation, urothelial thickening and cystic disease.
• Echogenicity should be less than liver and spleen.
• Increased echogenicity is indicated in renal disease.
• Renal cystic disease: APPKD, MCDK.
13. Amniotic fluid
• By 20 to 22 weeks the vast majority of amniotic fluid is fetal urine
• Oligohydramnios identified after 18 to 20 weeks’ gestation may be a
result of urinary tract obstruction or poor renal development.
16. Ureterovesical Obstruction
• Primary obstruction of the UVJ.
• Ectopic ureter inserting into the bladder neck.
• High-grade VUR.
• VUR.. Not easily diagnosed prenatally.
17. Renal Cystic Disease
• Multiple noncommunicating cysts, minimal or absent renal parenchyma, and the
absence of a central large cyst are diagnostic of MCDK.
• Bilaterally enlarged echogenic kidneys without renal cystic disease, particularly if
associated with hepatobiliary dilatation or oligohydramnios, suggest ARPKD.
• Moderately enlarged hyperechogenic kidneys with increased corticomedullary
differentiation suggest ADPKD.
• Congenital multilocular cystic nephroma (Cystic Wims Tumor).
22. PUV
• Bilateral hydroureteronephrosis.
• A thick-walled bladder with dilated posterior urethra (keyhole sign).
• In more severe cases, dysplastic renal parenchymal changes with
perinephric urinomas and urinary ascites.
23.
24. Bladder Exstrophy
• Non visualization of the fetal bladder.
• A lower abdominal wall mass immediately inferior to a low-lying umbilicus.
• Diminutive genitalia.
• Absence of bladder filling.
• Normal kidneys in orthotopic position, normal vertebrae and spinal cord.
• Abnormal symphyseal diastasis.
• Anteriorly displaced anus.
• Termination of pregnancy ??????????
25. Cloacal Exstrophy
• Omphalocele, Exstrophy, Imperforate anus, Spinal abnormality [OEIS].
• Non visualization of the bladder, a low-lying umbilicus, lower
abdominal wall mass, kidney (number, location, and/or appearance)
and lumbosacral spine abnormalities.
26. Cloacal Malformations
• Considered in any female fetus with hydronephrosis and a large pelvic cystic mass.
• Calcified meconium is an important sign.
• Fetal ascites, multicystic pelvic mass, bilateral hydronephrosis, and oligohydramnios
associated with meconium peritonitis.
• If polyhydramnios, suspect OA and TOF.
27.
28. Congenital Adrenal Hyperplasia
• Genital ambiguity in females can be reduced or eliminated with
prenatal dexamethasone treatment.
• As early as gestational week 12 by profiling maternal urine for steroid
metabolite excretion.
31. Renal Mass
• Congenital Mesoblastic Nephroma (CMN): is the most common neonatal mass, described as a
hypoechoic homogeneous or heterogeneous solid renal mass with an echogenic rim that is not
often well defined, a Vascular ring sign, usually in the 3rd trimester.
• Rhabdoid tumor of the kidney: large mass in the left renal area with concomitant massive
polyhydramnios.
• Beckwith-Wiedemann syndrome (BWS): macrosomia, polyhydramnios, omphalocele,
macroglossia, hepatomegaly, and renal enlargement
32. Renal vein thrombosis
• Renal enlargement, loss of corticomedullary differentiation,
echogenic streaks, lack of definition of renal sinus echoes, and loss of
venous flow in the affected kidney by Doppler imaging.
33.
34. Adrenal mass
• DD: neuroblastoma, adrenal hemorrhage, adrenal and cortical
renal cysts, adrenal adenoma and carcinoma, subdiaphragmatic
pulmonary sequestration, BWS, duplication of the renal system,
Wilms tumors, CMN, and mesenteric and enteric duplication cysts.
• Neuroblastoma is most often cystic, right sided, and identified in the third
trimester.
39. Why Fetal Interventions?
• Fetal urine comprises more than 90% of amniotic fluid volume by the
16th week of gestation.
• Oligohydramnios during the second trimester is often associated with
pulmonary hypoplasia.
• Prevent or delay ESRD.
45. Unilateral hydronephrosis
• It is important to keep in mind that a postnatal ultrasound evaluation performed within
the first 48 hours of life may not yet demonstrate hydronephrosis or may underestimate
the degree of hydronephrosis secondary to physiologic oliguria in the newborn.
• Infants with severe ANH should be placed on a prophylactic antibiotic (amoxicillin, 10 to
25 mg/kg/day) and undergo VCUG.
• Diuretic renography.
46. Bilateral hydronephrosis
• PUV, Bilateral VUR, Neurogenic bladder, Bilateral UPJO.
• BOO , in male suspect PUV, in female suspect ectopic ureter in the bladder
neck.
• In PUV, bladder decompression and chemoprophylaxis (amoxicillin 10 to 25
mg/kg/day) started immediately.
• Ultrasound and VCUG should be done immediately.
47. Solitary kidney
• Infants born with solitary kidneys (renal agenesis), renal ectopia,
or unilateral multicystic dysplasia should be evaluated postnatally by
ultrasonography.
• 30% have VUR, 11% UPJO, and 7% UVJO.
• VCUG and DMSA.
53. 1. Nonobstructive hydronephrosis
2. UPJO.
3. Unilateral cysts (MCDK).
4. Bilateral cysts (ARPKD/ ADPKD).
5. Midline cystic abdominal masses:
a. Hydrometrocolpos.
b. Ovarian cyst.
c. Distended bladder.
d. Urinary ascites.
54. Solid abdominal masses:
a. Neuroblastoma: the most common malignant abdominal neonatal tumor.
b. SCT.
c. CMN: the most common solid renal mass < 6 months.
d. Wilms’ tumor (WAGR, BWS), rhabdoid tumor, clear cell sarcoma, angiomyolipoma, and ossifying tumor of the kidney.
e. Renal vein thrombosis (RVT).
f. Renal artery thrombosis.
g. Adrenal hemorrhage.
h. Rhabdomyosarcoma.
i. Germ cell tumor.
56. Exstrophy epispadias complex
• Protect bladder mucosa.
• Suturing the cord, no plastic clamp.
• Good hydration.
• Latex allergy is increasing in those patients.
• Complete or staged repair.
60. Renal vein thrombosis
• Enlarged kidneys, hematuria, anemia, and thrombocytopenia.
• A history of a prolonged delivery, dehydration, sepsis, birth asphyxia, maternal
diabetes, protein C deficiency, umbilical catheter and prematurity.
• Male > female, left > right.
• Doppler ultrasonography.
• Good hydration, electrolytes correction, anticoagulants.
61. Adrenal Hemorrhage
• 1-2 % of healthy babies.
• Right > left side.
• Prolonged labor, birth trauma, and large birth weight, associated with RVT, BWS.
• Anemia, shock, and an abdominal mass, scrotal hemorrhage.
• Ultrasonography, MRI.
• Peripheral eggshell calcifications.
• DD : neuroblastoma ( urinary catecholamines).
• Supportive treatment.
62. Renal artery thrombosis
• Not common as a neonatal mass.
• Hypertension and hematuria in a neonate.
• Umbilical artery catheterization is the most common cause.
• Renal insufficiency, proteinuria and congestive heart failure.
• Doppler ultrasonography, CT Angiography.
• Thrombolytic therapy, Nephrectomy in persistent hypertension.