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1EuFMD | Open Session special edition | #OS20se
Vaccine Banks
A unique solution to address emergency
needs for quality vaccine
Pascal Hudelet
The VPH Center of
2
FMD vaccines: no stocks are available
• Constant competition between regular, predictable demand
and sudden surges due to
• Outbreaks in free or endemic countries
• Unexpected funding availability
• There is no idle manufacturing capacity ready to serve an
increase in demand
• Sales forecasts are often unreliable in a market mostly based on
tenders & orders with unrealistic delivery expectations
• Banks or Strategic reserves are the only available solution for
rapid access to vaccine from a supply perspective
60
80
100
120
140
3
Banks: an acknowledged tool for disease-free countries
• Today the antigen bank model is mostly used by FMD-free countries
• Trend toward mutualization of efforts
• International Vaccine Bank
• European Union
• North American FMD Vaccine Bank
• QUADS
• Downsides
• Financial & QA considerations => valuable antigen stock is often destroyed at the end of the
storage period
• Policies and preparedness plans not always aligned with vaccination
• Preferred options often remain 1/Stamping out 2/Vaccinate to Kill
4
Banks: a solution for endemic countries
• Banks can be used in endemic countries
• As a buffer stock to respond to sudden surges in demand
• As an insurance against introduction of exotic strains
• As trigger for pilot vaccination campaigns
• A regional approach is recommended - Regional banks funded by international
organizations:
• OIE SEACFMD bank
• OIE/WHO Rabies vaccine bank
• PAHO rabies
• Sustainable models should be invented
• Donor funding during first steps of PCP
• Provide support to put in place infrastructure needed for vaccination campaigns
• Perform economic analysis of benefits of vaccination
• Transfer to country ownership –once they realize vaccines are only a minor part of the cost of a
campaign
5
Conclusions
• Antigen and vaccine banks are one of the solutions to reach vaccine
security
• Today they are mostly used as by disease-free countries, as an
insurance, part of their risk mitigation strategy to mimize the
devastating consequences of outbreaks
• But they could also help minimize vaccine shortages in endemic
countries
• They may seem costly to put in place but guarantee access to quality
vaccine when needed

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OS20 - Solutions to vaccine security - a manufacturer's perspective - Pascal Hudelet

  • 1. 1EuFMD | Open Session special edition | #OS20se Vaccine Banks A unique solution to address emergency needs for quality vaccine Pascal Hudelet The VPH Center of
  • 2. 2 FMD vaccines: no stocks are available • Constant competition between regular, predictable demand and sudden surges due to • Outbreaks in free or endemic countries • Unexpected funding availability • There is no idle manufacturing capacity ready to serve an increase in demand • Sales forecasts are often unreliable in a market mostly based on tenders & orders with unrealistic delivery expectations • Banks or Strategic reserves are the only available solution for rapid access to vaccine from a supply perspective 60 80 100 120 140
  • 3. 3 Banks: an acknowledged tool for disease-free countries • Today the antigen bank model is mostly used by FMD-free countries • Trend toward mutualization of efforts • International Vaccine Bank • European Union • North American FMD Vaccine Bank • QUADS • Downsides • Financial & QA considerations => valuable antigen stock is often destroyed at the end of the storage period • Policies and preparedness plans not always aligned with vaccination • Preferred options often remain 1/Stamping out 2/Vaccinate to Kill
  • 4. 4 Banks: a solution for endemic countries • Banks can be used in endemic countries • As a buffer stock to respond to sudden surges in demand • As an insurance against introduction of exotic strains • As trigger for pilot vaccination campaigns • A regional approach is recommended - Regional banks funded by international organizations: • OIE SEACFMD bank • OIE/WHO Rabies vaccine bank • PAHO rabies • Sustainable models should be invented • Donor funding during first steps of PCP • Provide support to put in place infrastructure needed for vaccination campaigns • Perform economic analysis of benefits of vaccination • Transfer to country ownership –once they realize vaccines are only a minor part of the cost of a campaign
  • 5. 5 Conclusions • Antigen and vaccine banks are one of the solutions to reach vaccine security • Today they are mostly used as by disease-free countries, as an insurance, part of their risk mitigation strategy to mimize the devastating consequences of outbreaks • But they could also help minimize vaccine shortages in endemic countries • They may seem costly to put in place but guarantee access to quality vaccine when needed