Andy introduces ORMLite, an ORM library for Android. He demonstrates how to define data models with annotations, create database helpers to manage the underlying SQLite database, and implement DAO classes to perform CRUD operations and transactions on the data models. The code examples show how to define one-to-many relationships between User and Group data tables, and use the ORMLite API to easily insert, query, update, and delete records while handling transactions and relationships between the tables.