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Opening Doors to Better Care: Initiating and
Sustaining Open Access & Medication
Titration Clinics
Oksana Kamneva, PharmD, BCCP, CPP, BCCCP, BCPS
Ambulatory Heart Failure Pharmacist
Duke Cardiology
I have no financial conflicts of interest to report relating to the content
within this presentation
Disclosures
• Discuss implementation strategies to improve Guideline Directed
Medical Therapy (GDMT) utilization in patients with heart failure
Objective
Mebazaa et al. Lancet. 2022 Nov 4;S0140-6736(22)02076-1
Duke Cardiology Heart Failure Pharmacist GDMT Clinic
Oksana Kamneva,
PharmD
Full-time
Ambulatory Heart
Failure Pharmacist
Erika Nicolsen,
PharmD
Part-time
Ambulatory Heart
Failure Pharmacist
Jocelyn McAdoo,
CPh
Pharmacy
Technician
Patient Assistance
Program
Coordinator
Duke Cardiology Heart Failure Pharmacist Referral Process
Patient
-New HF dx
-Frequent
hospitalizations
Same Day
Access –
hospital
follow up
HF
Pharmacist
Cardiologist
50%
30%
10%
10%
Referral source
SDA 2F2G MD Inpatient Cardiology
Duke Cardiology Heart Failure Pharmacist Clinic Actions
Referral to HF
Pharmacist
•Preliminary medication access review
Virtual or In-
person visit
•Start/Titrate GDMT within days of referral and every 1-2 weeks
•Continued financial medication assistance
•IV iron therapy plans
Graduated
Patient
•Time to max tolerated GDMT is 6-8 weeks
•Transition of care
Duke Cardiology Heart Failure Pharmacist-April 2023- April 10, 2024
384
Referred Patients
89% visits
completed
virtually
15% no show rate
180 graduated
patients
1615 total in-
person and virtual
pharmacist visits
380 unique
distinct patients
Duke Cardiology Heart Failure Pharmacist-April 2023- April 2024
0
50
100
150
200
250
300
0%
20%
40%
60%
80%
100%
120%
140%
Apr May Jun Jul Aug Sep Oct Nov Dec Jan Feb Mar Apr
% of Clinic Capacity % No shows in person Patient Count
Duke Cardiology Heart Failure Pharmacist Medication Access
77% of HF GDMT clinic referred patients
received medication access assistance
48% of patients received copay assistance
400 Patient assistance (PAP) applications
Duke Cardiology Heart Failure Pharmacist GDMT Utilization- HFrEF
0.0%
10.0%
20.0%
30.0%
40.0%
50.0%
60.0%
70.0%
80.0%
90.0%
100.0%
BB ACE/ARB/ARNi ARNi MRA SGLT2i
Cardiology Other HF APP HF MD HF PharmD
46.9% 48.6% 50.5%
56.7%
82.7%
0.0%
10.0%
20.0%
30.0%
40.0%
50.0%
60.0%
70.0%
80.0%
90.0%
100.0%
Cardiology Other HF APP HF MD HF PharmD
QuadHFrEF
Duke Cardiology Heart Failure Pharmacist GDMT Utilization HFpEF/HFmrEF
21.78%
26.09%
30.92% 31.65%
88.71%
0.00%
10.00%
20.00%
30.00%
40.00%
50.00%
60.00%
70.00%
80.00%
90.00%
100.00%
Other HF MD HF APP Cardiology HF PharmD
HFpEF/HFmrEF patients on SGLT2i
Opening Doors to Better Care: Initiating and
Sustaining Open Access & Medication
Titration Clinics
Oksana Kamneva, PharmD, BCCP, CPP, BCCCP, BCPS
Ambulatory Heart Failure Pharmacist
Duke Cardiology
Oksana.Kamneva@duke.edu

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Opening Doors to Better Care: Initiating and Sustaining Open Access & Medication Titration Clinics

  • 1. Opening Doors to Better Care: Initiating and Sustaining Open Access & Medication Titration Clinics Oksana Kamneva, PharmD, BCCP, CPP, BCCCP, BCPS Ambulatory Heart Failure Pharmacist Duke Cardiology
  • 2. I have no financial conflicts of interest to report relating to the content within this presentation Disclosures
  • 3. • Discuss implementation strategies to improve Guideline Directed Medical Therapy (GDMT) utilization in patients with heart failure Objective
  • 4. Mebazaa et al. Lancet. 2022 Nov 4;S0140-6736(22)02076-1
  • 5. Duke Cardiology Heart Failure Pharmacist GDMT Clinic Oksana Kamneva, PharmD Full-time Ambulatory Heart Failure Pharmacist Erika Nicolsen, PharmD Part-time Ambulatory Heart Failure Pharmacist Jocelyn McAdoo, CPh Pharmacy Technician Patient Assistance Program Coordinator
  • 6. Duke Cardiology Heart Failure Pharmacist Referral Process Patient -New HF dx -Frequent hospitalizations Same Day Access – hospital follow up HF Pharmacist Cardiologist 50% 30% 10% 10% Referral source SDA 2F2G MD Inpatient Cardiology
  • 7. Duke Cardiology Heart Failure Pharmacist Clinic Actions Referral to HF Pharmacist •Preliminary medication access review Virtual or In- person visit •Start/Titrate GDMT within days of referral and every 1-2 weeks •Continued financial medication assistance •IV iron therapy plans Graduated Patient •Time to max tolerated GDMT is 6-8 weeks •Transition of care
  • 8. Duke Cardiology Heart Failure Pharmacist-April 2023- April 10, 2024 384 Referred Patients 89% visits completed virtually 15% no show rate 180 graduated patients 1615 total in- person and virtual pharmacist visits 380 unique distinct patients
  • 9. Duke Cardiology Heart Failure Pharmacist-April 2023- April 2024 0 50 100 150 200 250 300 0% 20% 40% 60% 80% 100% 120% 140% Apr May Jun Jul Aug Sep Oct Nov Dec Jan Feb Mar Apr % of Clinic Capacity % No shows in person Patient Count
  • 10. Duke Cardiology Heart Failure Pharmacist Medication Access 77% of HF GDMT clinic referred patients received medication access assistance 48% of patients received copay assistance 400 Patient assistance (PAP) applications
  • 11. Duke Cardiology Heart Failure Pharmacist GDMT Utilization- HFrEF 0.0% 10.0% 20.0% 30.0% 40.0% 50.0% 60.0% 70.0% 80.0% 90.0% 100.0% BB ACE/ARB/ARNi ARNi MRA SGLT2i Cardiology Other HF APP HF MD HF PharmD 46.9% 48.6% 50.5% 56.7% 82.7% 0.0% 10.0% 20.0% 30.0% 40.0% 50.0% 60.0% 70.0% 80.0% 90.0% 100.0% Cardiology Other HF APP HF MD HF PharmD QuadHFrEF
  • 12. Duke Cardiology Heart Failure Pharmacist GDMT Utilization HFpEF/HFmrEF 21.78% 26.09% 30.92% 31.65% 88.71% 0.00% 10.00% 20.00% 30.00% 40.00% 50.00% 60.00% 70.00% 80.00% 90.00% 100.00% Other HF MD HF APP Cardiology HF PharmD HFpEF/HFmrEF patients on SGLT2i
  • 13. Opening Doors to Better Care: Initiating and Sustaining Open Access & Medication Titration Clinics Oksana Kamneva, PharmD, BCCP, CPP, BCCCP, BCPS Ambulatory Heart Failure Pharmacist Duke Cardiology Oksana.Kamneva@duke.edu

Editor's Notes

  1. Rapid up-titration to 50% optimal doses before discharge, and up-titration of treatments to 100% of recommended doses within 2 weeks following discharge, and 4 scheduled outpatient visits over the 2 months after discharge
  2. Start/Titrate GDMT within days of referral and every 1 to 2 weeks Communication to referring provider and PCP on max tolerate GDMT doses, follow up ECHO, and ongoing patient assistance needs
  3. Duke HF Pharmacists April 2023 to April 10th 2024- 1615 total arrived and virtual visits, 380 unique distinct arrived patients, no show rate 15%, 89% visits completed virtually