The document discusses nucleotide biosynthesis in cells. It explains that there are two pathways for nucleotide synthesis: de novo synthesis and salvage pathways. It provides learning objectives about understanding these two pathways and how purines and pyrimidines are synthesized. Specifically, it outlines that purines are synthesized from IMP and that pyrimidines are synthesized from uracil and cytosine. The document directs the reader to its website for more detailed descriptions and additional learning materials on nucleotide biosynthesis.

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NUCLEOTIDEBIOSYNTHESIS
Bio-synthesis of Purines &Pyrimidines

2. “The formation of DNA's structure by Watson and Crick may turn out to be the
greatest developments in the field of molecular genetics in recent years”
Linus Pauling, 1953
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3. Learning objectives:
How nucleotides are synthesized in the cells?
Understand the TwoPathwaysof nucleotide biosynthesis
 (1). De-novo synthesis and (2). SalvagePathways
De-novo synthesis of purines
 SynthesisofIMP(precursor of adenine and guanine)
 Synthesis of Adenineand Guaninefrom IMP
De-novo synthesis of pyrimidines
 Synthesis of Uracil
 Synthesis of Cytosine
 Synthesis of deoxy nucleotides
 Synthesis of Thymine Salvage
pathwaysof Purines and Pyrimidines
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31. NUCLEOTIDEBIOSYNTHESIS
For detailed description of this topic, please visit:
 http://www.easybiologyclass.com/nucleotide-biosynthesis-de-
novo-salvage-purine-pyrimidine-nucleotides-cells/
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