This document summarizes a presentation on nonalcoholic fatty liver disease (NAFLD) in children and adolescents. It discusses the goals of screening and treatment of NAFLD, background information on prevalence and risk factors, and a randomized controlled trial on the effects of vitamin E and metformin for treating NAFLD in children. The trial found that neither vitamin E nor metformin was more effective than placebo in improving liver enzymes, but vitamin E showed some benefit in resolving nonalcoholic steatohepatitis (NASH) in children with baseline NASH. Overall, lifestyle changes focusing on weight loss remain the primary treatment approach for pediatric NAFLD due to lack of effective drug therapies.