This document discusses thrombocytopenia in neonates. It begins by defining thrombocytopenia as a platelet count below 150,000/mcL and notes its incidence is 0.7-0.9% generally but higher (22-35%) in NICUs. It then classifies thrombocytopenia by severity and lists various potential causes including alloimmune conditions, infections, genetic disorders, and others. Guidelines are provided for evaluation and management of early-onset versus late-onset thrombocytopenia as well as criteria for platelet transfusion in neonates. Specific conditions like NAIT are also explained in more detail.