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Narcolepsy
Shivani Suravarjjala, Pranav Ayyagari, Elizabeth Kelso, Evan Messenger
www.http://azcache.com/
Summary
Lifelong sleep disorder (Akintomide & Richards, 2011)
Daytime sleepiness + sleep attacks
Cataplexy
Hallucinations
Sleep paralysis
Genetic and environmental factors
Increased risk in children of people with narcolepsy
Environmental triggers are unknown
https://www.theodysseyonline.com
Symptoms
Common symptoms:
Chronic daytime sleepiness
Sleep paralysis (NINDS, 2016)
Can occur when falling asleep or waking up
Hallucinations
Cataplexy (NINDS, 2016)
Muscle weakness while a person is awake
Feeling of loss of voluntary muscle control
http://www.nejm.org/
Youtube Videos
Etiology
Exhibit low levels of hypocretin - NT
that promotes wakefulness
Loss of neurons that make hypocretin
Cause unknown, but it “appears to be
autoimmune in nature” (NINDS, 2016)
Traumatic brain injury, infections,
hormone changes, toxins, stress, and
diet
Usually occurs with no prior family
history
www.howsleepworks.com
www.prezi.com
Disease Diagnoses and Treatment/Management
Diagnoses of Narcolepsy (Akintomide & Richards, 2011)
Narcolepsy with cataplexy
Narcolepsy without cataplexy
Secondary Narcolepsy
Signs of Narcolepsy
Cataplexy and other physical symptoms
Polysomnography with MSLT test scores <8 minutes
Must rely on clinical symptoms and test results www.paradisesleep.com
Patient Support Groups
● Narcolepsy Network
● Organization provides:
○ Membership
○ Awareness
○ Donation site
○ Resource for support groups and nearby doctors
○ Research participation opportunities
● Support Groups
http://narcolepsynetwork.org/
References Cited
Akintomide, G. S., & Rickards, H. (2011). Narcolepsy: a review. Neuropsychiatric Disease and Treatment,
7, 507–518. http://doi.org/10.2147/NDT.S23624
Billiard, M. (2008). Narcolepsy: Current treatment options and future approaches. Neuropsychiatric Disease
and Treatment.
Narcolepsy fast facts. (2013). Retrieved from http://narcolepsynetwork.org/about-narcolepsy/ narcolepsy-
fast-facts/
Narcolepsy Network. (n.d.). Retrieved November 28, 2016, from http://narcolepsynetwork.org/
O., N., & N. (2016, April 6). Narcolepsy Fact Sheet. Retrieved November 14, 2016, from
http://www.ninds.nih.gov/disorders/narcolepsy/detail_narcolepsy.htm
N., & N. (2016, April 6). Narcolepsy Fact Sheet. Retrieved November 10, 2016, from
http://www.ninds.nih.gov/disorders/narcolepsy/detail_narcolepsy.htm

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Narcolepsy Powerpoint

  • 1. Narcolepsy Shivani Suravarjjala, Pranav Ayyagari, Elizabeth Kelso, Evan Messenger www.http://azcache.com/
  • 2. Summary Lifelong sleep disorder (Akintomide & Richards, 2011) Daytime sleepiness + sleep attacks Cataplexy Hallucinations Sleep paralysis Genetic and environmental factors Increased risk in children of people with narcolepsy Environmental triggers are unknown https://www.theodysseyonline.com
  • 3. Symptoms Common symptoms: Chronic daytime sleepiness Sleep paralysis (NINDS, 2016) Can occur when falling asleep or waking up Hallucinations Cataplexy (NINDS, 2016) Muscle weakness while a person is awake Feeling of loss of voluntary muscle control http://www.nejm.org/
  • 5. Etiology Exhibit low levels of hypocretin - NT that promotes wakefulness Loss of neurons that make hypocretin Cause unknown, but it “appears to be autoimmune in nature” (NINDS, 2016) Traumatic brain injury, infections, hormone changes, toxins, stress, and diet Usually occurs with no prior family history www.howsleepworks.com www.prezi.com
  • 6. Disease Diagnoses and Treatment/Management Diagnoses of Narcolepsy (Akintomide & Richards, 2011) Narcolepsy with cataplexy Narcolepsy without cataplexy Secondary Narcolepsy Signs of Narcolepsy Cataplexy and other physical symptoms Polysomnography with MSLT test scores <8 minutes Must rely on clinical symptoms and test results www.paradisesleep.com
  • 7. Patient Support Groups ● Narcolepsy Network ● Organization provides: ○ Membership ○ Awareness ○ Donation site ○ Resource for support groups and nearby doctors ○ Research participation opportunities ● Support Groups http://narcolepsynetwork.org/
  • 8. References Cited Akintomide, G. S., & Rickards, H. (2011). Narcolepsy: a review. Neuropsychiatric Disease and Treatment, 7, 507–518. http://doi.org/10.2147/NDT.S23624 Billiard, M. (2008). Narcolepsy: Current treatment options and future approaches. Neuropsychiatric Disease and Treatment. Narcolepsy fast facts. (2013). Retrieved from http://narcolepsynetwork.org/about-narcolepsy/ narcolepsy- fast-facts/ Narcolepsy Network. (n.d.). Retrieved November 28, 2016, from http://narcolepsynetwork.org/ O., N., & N. (2016, April 6). Narcolepsy Fact Sheet. Retrieved November 14, 2016, from http://www.ninds.nih.gov/disorders/narcolepsy/detail_narcolepsy.htm N., & N. (2016, April 6). Narcolepsy Fact Sheet. Retrieved November 10, 2016, from http://www.ninds.nih.gov/disorders/narcolepsy/detail_narcolepsy.htm