4. PATHOGENESIS
*Insudation hupothesis. The concept
hypothesised by Virchow in 1856 that
atherosclerosis is a form of cellular
proliferation of the intimal cell result ing
from increased imbibing of lipids from
the blood came to be called the ' lipids
theory' now it is known as 'Response to
injury hypothesis' and is now days most
widely accepted theory
5. Encrustation hypothesis
*The proposal put forth by Rokitansky in1852
that atheroma represented a form of
encrustation on the arterial wall from the
components in the blood forming thrombi
composed of platelets, fibrin and leucocytes
was named as' encrustation theory' or
'thrombogenic theroy'
