Material Safety Data Sheet (MSDS) for Cosmesome-Ubq (NE) a Proliposome formulation manufactured by Encapsula NanoSciences that is used specifically in the cosmetic industry. The brand name is Cosmesome-Ubq (NE). The Cosmesome-Ubq (NE) formulation is composed of saturated phospholipids and it does not contain alcohol. The proliposome formulation forms liposomes containing CoQ10 upon dilution with water. During the dilution process water soluble active ingredients can be encapsulated inside the liposomes or liposoluble active ingredients can be incorporated into the lipid bilayers.

1. Material Safety DataSheet
Version1.1
RevisionDate:06/05/2014
Print Date:08/06/2014
1. PRODUCT AND COMPANY IDENTIFICATION
Product name: COSMESOME TM- Ubq (NE)
Product Number: COS-1005
Brand: COSMESOME TM
Company Address: ENCAPSULA NANOSCIENCES LLC
6 CADILLAC DRIVE SUITE 245
BRENTWOOD, TN, 37027
Technical Phone: 615-884-4442
Fax: 615-250-8747
Emergency Phone: 615-438-8553
CHEMTREC: 1-800-424-9300
2. COMPOSITION/INFORMATION ON INGREDIENTS
Ingredient Name CAS# Percent
WATER 7732-18-5 >90
GLYCERIN 56-81-5
1, 3 Butanediol 107-88-0
UBIQUINONE 303-98-0
L-α-PHOSPHATIDYLCHOLINE, hydrogenated 97281-48-6 <5
3. HAZARDS IDENTIFCATION
OSHA
No known OSHA hazards
Hazard Statements
European Community Risk and Safety Phrases
S24/25- Avoid contact with skin and eyes
S37/39-Wear suitablegloves and eye/face protection
HMIS RATING
HEALTH HAZARDS: 1
FLAMMABILITY: 0
CHRONIC HEALTH HAZARDS: *
PHYSICAL HAZARDS: 0

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NFPA RATING
HEALTH HAZARD: 1
FLAMMABILTY: 1
REACTIVITY: 0
POTENTIAL HEALTH EFFECTS
Inhalation May be harmful if inhaled
Skin May be harmful if absorbed through skin.
Eyes May causeeye irritation.
Ingestion May be harmful if swallowed
Chronic May be harmful to mucus membranes and upper respiratory tract.
4. FIRST AID MEASURES
ORAL EXPOSURE
Do not inducevomiting. Never give anythingby mouth to an unconscious person.Rinsemouth with
water. Consulta physician
INHALATION EXPOSURE
If inhaled,remove to fresh air.If not breathing give artificial respiration.If breathingis difficult,give
oxygen. Consulta physician.
DERMAL EXPOSURE
In caseof contact, immediately wash skin with soap and copious amounts of water. Cover skin with
an emollient. Contact a physician.
EYE EXPOSURE
In caseof contact, check or remove any contact lenses; immediately flush eyes with copious amounts
of water for atleast20 minutes. Contact a physician.
5. FIRE FIGHTING MEASURES
FLAMMABILITY
Not available
EXTINGUISHING MEDIA
It is suitableto usewater spray,alcohol-resistantfoam,dry chemical or carbon dioxide.

3. Material Safety DataSheet
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SPECIAL PROCTECTIVE EQUIPMENT FOR FIRE-FIGHTERS
Wear self-contained breathingapparatus and protectiveclothingto prevent contactwith skin and
eyes. Included a positivepressureNIOSH approved self-contained breathingapparatus.
HAZARDOUS COMBUSTION PRODUCTS
Carbon oxides
SPECIAL REMARKS
N/A
6. ACCIDENTAL RELEASE MEASURES
METHODS FOR CLEANING UP
Soak up inert absorbentmaterial and disposeof as waste. Keep in suitablecontainer for disposal.
Use appropriatetools to put this spilled solid in a convenientwaste disposablecontainer and finish
cleaningby spreadingwater on the contaminated surfaceand disposeof according to local and
region authority requirements. Allowto evacuate through the sanitary system.
ENVIRONMENTAL PRECAUTIONS
Do not let product enter drains.If safeto do so prevent further leakages or spills.
PERSONAL PRECAUTIONS
Use personal protective equipment. Avoid breathingin vapors,mist or gas. Ensure adequate
ventilation.Prepareevacuation sites.
7. HANDLING AND STORAGE
HANDLING
User Exposure: Do not breathe vapor, dust, fume, gas, mistand spray.Avoid prolonged or repeated
exposure. Do not get in eyes, on skin,on clothing. Wash hands thoroughly after handling.
STORAGE
Suitable:Keep tightly container closed.Store in temperature between approximately 2-8 o C.Do not
freeze keep in refrigerator. Product is sensitiveto moisture and light.
8. EXPOSURE CONTROLS/ PERSONAL PROTECTION
ENGINEERING CONTROLS
Safety shower and eye bath. Mechanical exhaustrequired.
PERSONAL PROTECTIVE EQUIPMENT
Respiratory:Use respirators and components tested and approved under appropriategovernment
standards such as NIOSH(US) in accord with 29 CFR 1910.134,useeither an atmosphere supply
respirator or air purifyingrespirator. Also usea full-facerespirator with multi-purposecombination

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(US) or type ABEK (EN 14387) respirator cartridges as a back up to engineering controls.If the
respirator is thesolemeans of protection, usea full-facesupplied airsrespirator.Userespirators
and components tested and approved under appropriategovernment standers such as NIOSH(US)
or CEN (EU).
Hand: Compatible chemical-resistantgloves.
Eye: Chemical safety goggles. Safety glasses with side-shieldsconformingto EN 166 use equipment
for eye protection listed and approved under appropriated government standards such as NIOSH
(US) or EN166 (EU)
Skin and Body: Wear a complete suitprotecting againstchemicals.
GENERAL HYGIENE MEASURES
Wash hands thoroughly after handling.Wash contaminated clothingbefore reuse. Prepare all
materials under the fume hood and avoid generating aerosols.
9. PHYSICAL AND CHEMICAL PROPERTIES
Appearance
white, viscous liquid
Safety data
N/A
Melting point
N/A
Boiling point
N/A
Flash point
N/A
Ignition Temperature
N/A
Lower explosion limit
N/A
Upper Explosion limit
N/A
Water Solubility
N/A
Density
N/A

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10. STABILITY AND REACITIVITY
STORAGE STABILITY
Store under recommended conditions.
MATERIALS TO AVIOD
Strong oxidizingagents
HAZARDOUS DECOMPOSITION PRODUCTS
N/A
CONDITIONS TO AVOID
Light and exposure to moisture. Strong bases and Strong oxidizingagents.
11. TOXICOLOGICAL INFORMATION
CARCINOGENICITY
This product contains a component that has been reported to be carcinogenic based on its IARC, OHSA, ACGIH,
NTP, or EPA classification.
IARC: No component of this product present atlevels greater than or equal to 0.1% is identified as
probable,possibleor confirmed human carcinogen by the IARC.
OHSA: No component of this product present atlevels greater than or equal to 0.1% is identified as
probable,possibleor confirmed human carcinogen by the OHSA.
ACGIH: No component of this product present atlevels greater than or equal to 0.1% is identified as
probable,possibleor confirmed human carcinogen by the ACGIH.
EPA: No component of this product present atlevels greater than or equal to 0.1% is identified as
probable,possibleor confirmed human carcinogen by the EPA.
CHRONIC
CoQ10-investigated as a reproductive effector and teratogen. Only select Reregister or Toxic of
Chemical Substances (RTECS) data as presented here. See actual entry RTECS for complete
information.CoQ10 RTECS number: DK3900000
ACUTE TOXICITY
1,3-Butanediol:Oral LD50- mouse rat-698 mg/kg
Symptoms: Sense organs and special senses (eye-lacrimation;muscleweakness;diarrhea)
Dermal LD50- rabbit>20,000 mg/kg
Glycerin:Oral LD50- mouse rat-698 mg/kg
Symptoms: Sense organs and special senses (eye-lacrimation;muscleweakness;diarrhea)
Dermal LD50- rabbit>20,000 mg/kg

6. Material Safety DataSheet
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RevisionDate:06/05/2014
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ADDITIONAL INFORMATION
Prolonged or repeated exposure may resultin Nausea, Headache, or Vomiting
Kidney- irregularities-based on Human evidence
ROUTE OF EXPOSURE
Skin Contact: May causeskin irritation
Skin Absorption: May be harmful if absorbed through the skin
Eye Contact: May Causeeye irritation
Inhalation: Materials may be irritatingto mucous membranes and upper
respiratory tract.
Ingestion: May be harmful if swallowed
SIGNS AND SYMPTOMS OF EXPOSURE
Symptoms have not be thoroughly investigated
12. ECOLOGICAL INFORMATION
Elimination information (persistenceand degradability)
Avoid releaseinto the environment.
Ecotoxicity effects
Runoff from firecontrol or dilution water may causepollution.
Further information on ecology
N/A
13. DISPOSAL CONSIDERATIONS
PRODUCT
Observe all federal,state, and local environment regulations. Contacta licensed professional waste
disposal serviceto remove this material.
CONTAMINATED PACKAGING
Observe all federal,state, and local environment regulations.
14. TRANSPROT INFORMATION
DOT (US)
Not dangerous goods
IMDG
Not dangerous goods
IATA
Not dangerous goods

7. Material Safety DataSheet
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RevisionDate:06/05/2014
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15. REGULATORY INFORMATION
OSHA HAZARDS
OSHA: Hazardous by definition of Hazard Communication Standard (29 SFR 1910.1200).EINECS:
this product is on the European Inventory of ExistingCommercial Chemical Substances
SARA 302 COMPONENTS
SARA 302: No chemicals in this material aresubjectto the reporting requirements of SARA Title
III,Section 302
SARA 313 COMPONENTS
SARA 313: This material does not contain any chemical components with known CAS numbers
that exceed threshold (De Minimis) reportinglevels established beSARA Title III,Section 313
SARA 311/312 HAZARDS
Acute health hazards,chronic health hazards,firehazards
MASSACHUSETTS RIGHT TO KNOW COMPONENTS
CAS-No. Revision Date
Glycerol 56-81-5 2007-03-01
PENNSYVANIA RIGHT TO KNOW COMPONENTS
CAS-No. Revision Date
L-α-PHOSPHATIDYLCHOLINE, hydrogenated 97281-48-6 1989-08-11
Glycerol 56-81-5 2007-03-01
Butane-1,3-diol 107-88-0
Water 7732-18-5
Coenzyme Q-10 303-98-0
NEW JERSEY RIGHT TO KNOW COMPONENTS
CAS-No. Revision Date
L-α-PHOSPHATIDYLCHOLINE, hydrogenated 97281-48-6 1989-08-11
Glycerol 56-81-5 2007-03-01
Butane-1,3-diol 107-88-0
Water 7732-18-5
Coenzyme Q-10 303-98-0
CALIFORNIA PROP. 65 COMPONENTS
CAS-No. Revision Date
L-α-PHOSPHATIDYLCHOLINE, hydrogenated 97281-48-6 1989-08-11
Canada
CAS# 7732185 is listed on Canada's DSLList

8. Material Safety DataSheet
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TSCA
CAS# 7732185 is listed on the TSCA Inventory
This SDS was prepared in accordance29 CFR 1910.1200,regulation (EC) No. 1272-2008,and
European directive67/548/EEC as amended.
16. OTHER INFORMATION
Copyright 2013 Encapsula NanoSciences LLC licensegranted to make unlimited paper copies for internal
use only.
The above information is believed to be correct but does not supportto be all inclusiveand shall beused
only as a guide. The information in this document is based on the present state of our knowledge and is
applicableto the product with regard to appropriatesafety precautions.It does not represent any
guarantee of the properties of the product. Encapsula NanoSciences LLC shall notbe held liablefor any
damage resultingfrom handlingor from contact with the above product.