- The document describes a study that implemented a Mobile Smoking Cessation Service (MSCS) in Malaysia to help smokers quit at their workplaces. - 155 smokers were enrolled and randomly assigned to receive either varenicline (Viva QS) or placebo medication, along with counseling. Follow-ups occurred at weeks 2, 4, 12, and 24. - At the 24-week follow-up, the 7-day abstinence rate was higher in the varenicline group compared to the placebo group (30.7% vs 13.9%). Abstinence rates were also higher in the varenicline group at weeks 4 and 12. - The MSCS

1. MOBILE SMOKING CESSATION SERVICES (MSCS) TO ACHIEVE SMOKEFREE WORKPLACES Zaswiza MN* , M Haniki NM*, M Aznan MA**, Samsul D**, S Halimah Bux*, N Syafinaz AR*. * KULLIYYAH OF PHARMACY, INTERNATIONAL ISLAMIC UNIVERSITY MALAYSIA, PAHANG. ** KULLIYYAH OF MEDICINE, INTERNATIONAL ISLAMIC UNIVERSITY MALAYSIA, PAHANG.

9. RANDOMIZATION: RANDOMIZED DOUBLE BLIND PLACEBO CONTROL TRIAL 2 GROUPS : PHARMACOTHERAPY VS. PLACEBO n = 75 n = 72 (2)

11. (5) FOLLOW-UP WEEK 12 OR Face-to –face interview / counselling Plus CO test ( in addition to self-reported smoking status) Telephone interview / counselling NO CO test (self-reported smoking status)

13. RESULT

16. CHARACTERISTICS OF SMOKERS AT BASELINE b n = 144. Three (3) subjects with missing data. * Total n = 147 Characteristics n (%) * Age (years) 18-30 52 (35.4) 31-45 71 (48.3) 46-60 24 (16.3) Race Malay 145 (98.6) Others 2 (1.4) Marital status b Married 125 (86.8) Never married or divorced 19 (13.2) Education Secondary school 42 (28.6) Certificate 20 (13.6) Degree/ Diploma 85 (57.8)

17. CHARACTERISTICS OF SMOKING HISTORY AT BASELINE a The FTND is a validated 6-items instrument to measure the level of dependence to nicotine. The total score range is 0 to 10, with ≥6 indicating high dependence . Characteristics n (%) Age begin smoking (years), n (%) 10-15 41 (27.9) 16-20 87 (59.2) 21-40 19 (12.9) Current tobacco use (No. of cigarette smoked per day), n (%) 1-10 sticks 35 (23.8) 11-20 sticks 91 (61.9) > 20 sticks 21 (14.3) Mean (SD) Carbon monoxide (CO) level (ppm) 11.50 (4.564) Modified Fagerstrom test score for nicotine dependence (FTND) a 5.03 (1.394)

18. 7-days prevalence abstinence at week 24 * P < o.o5 QUITTERS , n(%) SMOKERS, n(%) P Value (Pearson Chi-square) OR (95% CI) 33 (22.4) 114 (77.6) 0.015 * 2.74 (1.20-6.28) Viva QS Placebo Viva QS Placebo 23 (30.7) 10 (13.9) 52 (69.3) 62 (86.1)

19. 7-days prevalence abstinence at week 4 and week 12 * P < 0.05 QUITTERS, n(%) SMOKERS, n(%) P Value (Pearson Chi-square) OR (95% CI) Week 4 51 (34.7) 96 (65.3) 0.038 * 2.08 (1.04-4.16) Viva QS Placebo Viva QS Placebo 32 (42.7) 19 (26.2) 43 (57.3) 53 (73.6) Week 12 36 (24.5) 111 (75.5) 0.031* 2.35 (1.07-5.17) Viva QS Placebo Viva QS Placebo 24 (32.0) 12 (16.7) 51 (68.0) 60 (83.3)