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Amalina Aminuddin
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Contents
 Introduction
 Etiology
 Approach
 Investigations
 Congestive heart failure
Introduction
 Aka Shortness of breath, breathlessness,
dyspnea
“Abnormally uncomfortable awareness of
breathing”
 Harrison's Principles of Internal Medicine, 16th Edition
“A subjective experience of breathing
discomfort that consists of qualitatively distinct
sensations that vary in intensity“
 American Thoracic Society
Etiologies
Respiratory
 Parenchyma
 Pulmonary embolism
 Bronchiolitis
 Bronchial asthma
 Pneumonia
 Pulmonary
hypertension
 Airway
 Foreign body
aspiration
 Croup
 Epiglotitis
Respiratory: Newborn
Cause Time of onset
Meconium aspiration
syndrome
First few hours of life
Respiratory distress
syndrome
First 6 hours of life
Transient tachypnea of
newborn
First 6 hours of life
Persistent pulmonary
hypertension
Any age
Congenital malformations Any age
Cardiac Others
 Congestive heart
failure
 Congenital heart
disease
 Allergies
 High altitude
 Emotional distress
(anxiety, stress, panic
attack)
 Obesity
Approach
 Assess severity
 Evaluate history and
physical examination
 Distinguish between
respiratory and cardiac
causes
i) Grading
i) Grading
ii) Red flag signs
 Sudden onset
 Dyspnea at rest
 Decreased level of consciousness
 Accessory muscle use
 Tightness in the throat or barking crouping cough
 Chest pain
 Wheezing
History
 Onset, duration, course, severity , exacerbating
factors (allergen exposure, cold, exertion, supine
position)
 Any other associated symptoms
 chest pain or pressure (pulmonary embolism, myocardial
ischemia, pneumonia)
 dependent edema, orthopnea, and paroxysmal nocturnal
dyspnea (heart failure)
 fever, chills, cough, and sputum production (pneumonia)
 weight loss or night sweats (cancer or chronic lung
infection)
 Past history: asthma, heart disease, TB, pneumonia
Physical examination
 Vitals
 Examination focuses on the cardiovascular and
pulmonary systems.
Distinguishes
Respiratory Cardiovascular
 Cough with
expectorant
 Fever
 Seasonal variation
 Abnormal breath
sounds
 PND and orthopnea
 Associated syncope,
palpitation, anginal
pain
 Distended neck vein,
edema
 Pulse oximetry
 Chest X Ray
 ECG
 ABG
 Echocardiography
 Bronchoscopy
Initial studiesInvestigations
Congestive
Cardiac
Failure
1. Inability of the heart to maintain output (systolic
failure)
2. Inability to receive blood into ventricles at low
pressure during diastole (diastolic failure)
Etiology
Infants Children
 Congenital heart disease
 Myocarditis and primary
myocardial disease
 Tachyarrhythmias and
bradyarrythmias
 Pulmonary hypertension
 Miscellaneous causes :
Anemia, hypoglycemia,
infections, hypocalcemia,
neonatal asphyxia
 RF, RHD
 CHD complicated with
anemia, infection,
endocarditis
 Systemic hypertension
 Myocarditis, primary
myocardial disease
 Pulmonary
hypertension
Systolic
dysfunction
Diastolic
dysfunction
 Myocarditis
 Valvular lesions
causing stenosis or
regurgitation
 CAD
 Myocardial ischemia
 Cardiomyopathy
 Drugs and toxic
agents
 Mitral or tricuspid
stenosis
 Constrictive pericarditis
 Restrictive
cardiomyopathy
 Myocardial ischemia
 Marked ventricular
hypertrophy
 Dilated cardiomyopathy
Onset of Congestive Heart Failure
Age Lesion
Birth – 1 week Congenital mitral and tricuspid regurgitation,
neonatal Ebstein anomaly
1 – 4 weeks PDA in preterms, VSD with coarctation, persistent
truncus arteriosus, transposition with large VSD or
PDA, severe coarctation, congenital mitral or aortic
stenosis
1 – 2 months Transposition with VSD or PDA, VSD, PDA,
endocardial cushion defect, severe coarctation
2 – 6 months VSD, PDA, endocardial cushion defect
Clinical features
 Poor weight gain
 Facial puffiness, pedal edema
 Poor feeder
 Irritability, excessive perspiration and
restlessness
 Breathes too fast ; breathes better when
held against shoulder
Investigations
• Chest X-ray
• ECG
• ECHO
• Blood culture
• Hemoglobin for anaemia
• Arterial blood gas
Treatment
Reducing cardiac work
Inotropic agents
Reduce preload
Correcting the underlying
cause
1) Reduce Cardiac Work
 Restrict activity
 Treat fever, anemia, infection
 Neonate:
 Incubator ,inclined position with oxygen
 Restless child:
 Morphine sulfate 0.05mg/kg SC
 Midazolam
 Vasodilators
 Nitrates, hydralazine, ACE inhibitors
2) Inotropic Agents
 Digoxin :
 Initial ½
 ¼ in 6-8 hr
 Cathecolamines inotropes : dopamine,
dobutamine and adrenaline
 PDE inhibitor : milrinone, amrinone
Age Dose (mg.kg) Maintainance
Premature/
neonates
0.04 mg/kg , 1/4
1 month – 1
year
0.08 mg/kg, 1/3 to 1/4
1-3 year : 0.06 mg/kg, 1/3 to 1/4
Above 3 year : 0.04 mg/kg, 1/3
3) Reduce preload
 Diuretics
 Frusemide 1-3mg/kg/d oral
 Spirinolactone 1 mg/kg orally every 12 hours
 Restrict sodium intake
Prognosis
 High mortality
 Prognosis depend on underlying cause
Reference
 Vinod, Arvind, Ghai Essential Pediatrics ,8th
edition
 Kliegman, Stanton, St Geme, Schor, Nelson
Textbook of Pediatric, 1st south asian edition
 N. K. Burki, MD, PHD, acute dyspnea: is the
cause cardiac or pulmonary—or
both?,November 16, 2012
 Cardinal symptoms in cardiology... an analysis Dr
S Venkatesan.MD,DM Madras Medical college
SIMS March 4 th 2016
 http://www.msdmanuals.com/professional/pulmonary-
disorders/symptoms-of-pulmonary-
disorders/dyspnea#false

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Mellss yr5 paeds breathing difficulties (congestive cardiac failure)

  • 2. Contents  Introduction  Etiology  Approach  Investigations  Congestive heart failure
  • 3. Introduction  Aka Shortness of breath, breathlessness, dyspnea “Abnormally uncomfortable awareness of breathing”  Harrison's Principles of Internal Medicine, 16th Edition “A subjective experience of breathing discomfort that consists of qualitatively distinct sensations that vary in intensity“  American Thoracic Society
  • 5. Respiratory  Parenchyma  Pulmonary embolism  Bronchiolitis  Bronchial asthma  Pneumonia  Pulmonary hypertension  Airway  Foreign body aspiration  Croup  Epiglotitis
  • 6. Respiratory: Newborn Cause Time of onset Meconium aspiration syndrome First few hours of life Respiratory distress syndrome First 6 hours of life Transient tachypnea of newborn First 6 hours of life Persistent pulmonary hypertension Any age Congenital malformations Any age
  • 7. Cardiac Others  Congestive heart failure  Congenital heart disease  Allergies  High altitude  Emotional distress (anxiety, stress, panic attack)  Obesity
  • 8. Approach  Assess severity  Evaluate history and physical examination  Distinguish between respiratory and cardiac causes
  • 11. ii) Red flag signs  Sudden onset  Dyspnea at rest  Decreased level of consciousness  Accessory muscle use  Tightness in the throat or barking crouping cough  Chest pain  Wheezing
  • 12. History  Onset, duration, course, severity , exacerbating factors (allergen exposure, cold, exertion, supine position)  Any other associated symptoms  chest pain or pressure (pulmonary embolism, myocardial ischemia, pneumonia)  dependent edema, orthopnea, and paroxysmal nocturnal dyspnea (heart failure)  fever, chills, cough, and sputum production (pneumonia)  weight loss or night sweats (cancer or chronic lung infection)  Past history: asthma, heart disease, TB, pneumonia
  • 13. Physical examination  Vitals  Examination focuses on the cardiovascular and pulmonary systems.
  • 14. Distinguishes Respiratory Cardiovascular  Cough with expectorant  Fever  Seasonal variation  Abnormal breath sounds  PND and orthopnea  Associated syncope, palpitation, anginal pain  Distended neck vein, edema
  • 15.  Pulse oximetry  Chest X Ray  ECG  ABG  Echocardiography  Bronchoscopy Initial studiesInvestigations
  • 17. 1. Inability of the heart to maintain output (systolic failure) 2. Inability to receive blood into ventricles at low pressure during diastole (diastolic failure)
  • 18. Etiology Infants Children  Congenital heart disease  Myocarditis and primary myocardial disease  Tachyarrhythmias and bradyarrythmias  Pulmonary hypertension  Miscellaneous causes : Anemia, hypoglycemia, infections, hypocalcemia, neonatal asphyxia  RF, RHD  CHD complicated with anemia, infection, endocarditis  Systemic hypertension  Myocarditis, primary myocardial disease  Pulmonary hypertension
  • 19. Systolic dysfunction Diastolic dysfunction  Myocarditis  Valvular lesions causing stenosis or regurgitation  CAD  Myocardial ischemia  Cardiomyopathy  Drugs and toxic agents  Mitral or tricuspid stenosis  Constrictive pericarditis  Restrictive cardiomyopathy  Myocardial ischemia  Marked ventricular hypertrophy  Dilated cardiomyopathy
  • 20. Onset of Congestive Heart Failure Age Lesion Birth – 1 week Congenital mitral and tricuspid regurgitation, neonatal Ebstein anomaly 1 – 4 weeks PDA in preterms, VSD with coarctation, persistent truncus arteriosus, transposition with large VSD or PDA, severe coarctation, congenital mitral or aortic stenosis 1 – 2 months Transposition with VSD or PDA, VSD, PDA, endocardial cushion defect, severe coarctation 2 – 6 months VSD, PDA, endocardial cushion defect
  • 21. Clinical features  Poor weight gain  Facial puffiness, pedal edema  Poor feeder  Irritability, excessive perspiration and restlessness  Breathes too fast ; breathes better when held against shoulder
  • 22.
  • 23. Investigations • Chest X-ray • ECG • ECHO • Blood culture • Hemoglobin for anaemia • Arterial blood gas
  • 24. Treatment Reducing cardiac work Inotropic agents Reduce preload Correcting the underlying cause
  • 25. 1) Reduce Cardiac Work  Restrict activity  Treat fever, anemia, infection  Neonate:  Incubator ,inclined position with oxygen  Restless child:  Morphine sulfate 0.05mg/kg SC  Midazolam  Vasodilators  Nitrates, hydralazine, ACE inhibitors
  • 26. 2) Inotropic Agents  Digoxin :  Initial ½  ¼ in 6-8 hr  Cathecolamines inotropes : dopamine, dobutamine and adrenaline  PDE inhibitor : milrinone, amrinone Age Dose (mg.kg) Maintainance Premature/ neonates 0.04 mg/kg , 1/4 1 month – 1 year 0.08 mg/kg, 1/3 to 1/4 1-3 year : 0.06 mg/kg, 1/3 to 1/4 Above 3 year : 0.04 mg/kg, 1/3
  • 27. 3) Reduce preload  Diuretics  Frusemide 1-3mg/kg/d oral  Spirinolactone 1 mg/kg orally every 12 hours  Restrict sodium intake
  • 28. Prognosis  High mortality  Prognosis depend on underlying cause
  • 29. Reference  Vinod, Arvind, Ghai Essential Pediatrics ,8th edition  Kliegman, Stanton, St Geme, Schor, Nelson Textbook of Pediatric, 1st south asian edition  N. K. Burki, MD, PHD, acute dyspnea: is the cause cardiac or pulmonary—or both?,November 16, 2012  Cardinal symptoms in cardiology... an analysis Dr S Venkatesan.MD,DM Madras Medical college SIMS March 4 th 2016  http://www.msdmanuals.com/professional/pulmonary- disorders/symptoms-of-pulmonary- disorders/dyspnea#false

Editor's Notes

  1. ); chronic bronchitis or emphysema
  2. Tracheoesophygeal fistula, diap hernia
  3. Myocarditis, arrYthmia, pul hypertensio, rheumatic fever,
  4.  Grading of dyspnea NYHA MRC ATS Borg Yale Minnesota
  5. Dyspnea, palpitation, fatigue grading due to cardiac cause
  6. Sternomastoid, scaleneus ant, pec major n minor, ser ant, lat dorsi Can compromise airway patency Most likely cardiac origin
  7. fever, tachycardia, and tachypnea adequacy of air entry and exit, symmetry of breath sounds, and presence of crackles, rhonchi, stridor, and wheezing. Signs of consolidation (eg, egophony, dullness to percussion) . The cervical, supraclavicular, and inguinal areas for lymphadenopathy. Neck veins , pitting edema (both suggesting heart failure). Heart sounds should be auscultated with notation of any extra heart sounds, muffled heart sounds, or murmurConjunctiva should be examined for pallor. Rectal examination and stool guaiac testing should be done.
  8. O2 saturation, distinguish rs n cvs prob , abg – developing any acid base imbalance , echo n broncho to locate any structural deformity Advantages of VBG include less pain to the patient and ability to draw concurrently with other labs A normal venous pH, pCO2, and HCO3 rules out severe acid base abnormalities A venous pH of > 7.25 predicts an arterial pH of > 7.2 in 98% of cases (Conversely, a venous pH of < 7 predicts an arterial pH of < 7.2 in 98% of cases) A venous pCO2 of > 45 mm Hg is predictive of an arterial pCO2 of > 50 mm Hb Venous blood gasses do not allow adequate determination of the arterial concentration of oxgyen (paO2) and is not as useful to quantify oxygen delivery to target tissues
  9. Croup Symptoms: barking cough stridor retractions Treatment: Oral or IM dexamethasone Oxygen Keep NPO Nebulized racemic epinephrine with observation for at least 2 hours after treatment Anaphylaxis Symptoms: Stridor or wheezing Dizziness Vomiting or diarrhea Hives or facial swelling Treatment: IM/IV epinephrine Albuterol (if bronchospasm is present) Treat hypotension Diphenhydramine Ranitidine Methylprednisolone
  10. Assisted ventilation for patients with lower airway obstruction should be at a slow rate with adequate expiratory time to decrease the risk of air trapping and complications with high airway pressure including pneumothorax, gastric distension, regurgitation and aspiration.
  11. For more information regarding specific etiologies of lung tissue disease: Infectious pneumonia Symptoms: fever, tachypnea, hypoxemia, increased work of breathing, crackles or decreased breath sounds Management: Ancillary testing: ABG/VBG, CXR, viral studies, CBC, BCx Antibiotics to treat gram + organisms, consider macrolide coverage Albuterol if wheezing Reduce temperature if febrile Aspiration pneumonia Symptoms: coughing or gagging associated with feeding, more common in children with abnormal neurologic status Management Respiratory support and antibiotics if infiltrate is present on CXR Non-cardiogenic pulmonary edema (ARDS) Symptoms: pulmonary or systemic insult to the alveolar-capillary unit with release of inflammatory mediators Management Correction of hypoxemia Intubate if hypoxemia is refractory to high inspired oxygen concentrations Cardiogenic pulmonary edema Symptoms: fluid accumulation in the lung interstitium due to elevated pulmonary capillary pressure Management Ventilatory support Support cardiovascular function
  12. Disordered control of breathing can be due to elevation of intracranial pressure or depressed level of consciousness due to CNS infection, seizures, metabolic disorders, poisoning or drug overdose.
  13. Most important cause of breathing difficulties due to cardiac problems
  14. Small feed: easy fatigue, excessive calorie loss due to inc work of breathing, Unusual weight gain Baby does not take more than 2 ounces of milk at a time, hungry within a few minutes Persisting hunger due to small feeds Equivalent to orthopnea in older children Signs of left ventricular failure
  15. Common feature to left n right failure r cardiac enlargement, poor peri pulse w/wo cyanosis
  16. : to differentiate between cardiac and respiratory disease: changes will give clue about diagnosis– vegetations suggestive of infective endocarditis (IE
  17. Duct dep systemic circulation ( AS, interrupted aortic arch ,coA) prostaglandin
  18. PRBC 10-20ml/kg if severe anemia Temp 36-37 minimal met need, humidified O2 40-50% Dec catecholamine ,anxietyphys activity Catecholamine- mediated :Arterial constrction inc Syst vascular resistantce inc work of heart…… veno const inc venous return inc venous return Cough ….Captopril,enalapril: cause cough, may need ARB (losartan) Vasodilator indication: acute A/M regurgitation, ventr dysfunction,
  19. Rapid onset, quick elimination,¼ in next 6-8 hr Before 3rd dose, ECG must be don Ino + peri vsd i
  20. Pot sparing : triamterene, spririno, amiloride ….reduce arrythmia Diff to implement, avoid salt rich food- chips,pickle