Brought to you by the Mobile Collective, with the support of the ICT KTN, the CI KTN, and the Mobile Applications Centre at Imperial College.
Featuring: Patients Know Best, Wellnote, Epicollect, & MoDiSe
Medicine 2.0 for the Emergency Department & Public Health - Beyond the Basicsnickgenes
Emergency Departments (EDs) are the gateway to healthcare for the majority of Americans. There are over 125 million ED visits a year. One-third of these visits are due to injury, one-eighth to mental illness or substance abuse, and over one-third are from patients who are under- or un-insured. ED patients are often the members of society who are the most at-risk for poor health outcomes and also those with the fewest resources to address their acute or chronic medical conditions.
Yet ED patients have tremendous access to technology: recent studies show that despite low socioeconomic status, 95% of ED patients own cellphones, 93% access the internet, and 65% have smartphones. Technology provides potential solutions to perennial barriers to improving the health of the ED population, such as time constraints, access to post-ED care, and fidelity of interventions. And the ED patient population provides potential solutions to many perennial challenges for public health research: accessing difficult-to-reach populations, adequately sampling the most at-risk, and proving real-world efficacy.
This panel discussion will feature emergency physician-researchers, each of whom are currently conducting funded research on technology-based public health interventions. We will discuss the ways in which we have successfully stretched the boundaries of “Medicine 2.0” (interactive computer programs, text messaging, social media) to improve the health of the ED population. We will discuss ways to translate technology’s efficiency, efficacy and fidelity into the hectic ED environment. We will also outline some of the reasons to test mHealth innovations in the ED environment.
The use of mHealth to impact this at-risk population is imperative. Yet it is something that few researchers, computer scientists, pharmaceutical companies, mental health professionals, or hospital administrators have done. By the close of this panel discussion, attendees will have attained critical knowledge about the advantages of, and possibilities for, extending mHealth into the ED setting.
Panelists:
* Esther K. Choo, MD MPH, Assistant Professor of Emergency Medicine at Brown University, has grants from NIDA to develop interactive, computer-based interventions to address partner violence and substance use in the ED.
* Nick Genes, MD PhD is Assistant Professor of Emergency Medicine at Mt Sinai School of Medicine. Dr. Genes has spoken at national conferences on the utility of social media for physicians career development and ED community relations, and is researching physician usage of social media tools, HIT, and patient-support tools.
* Megan L Ranney, MD MPH is Assistant Professor of Emergency Medicine at Brown University, a core researcher in the Injury Prevention Center of Rhode Island Hospital. Her research includes using text-messaging to assess and deliver interventions to adolescent ED patients.
Scheduled to open in September 2012, St. Bernard Parish Hospital will bring quality healthcare back home to St. Bernard Parish. It also promises to serve as a catalyst for economic and community recovery in an area of Louisiana that was destroyed by Hurricane Katrina.
Principles And Practice Of Clinical Research Ap 2007Jyoti Batra
A very good book on clinical research. Includes everything from introducton to trials methodology etc..
A must read for clinical resaearch professional!!
Medicine 2.0 for the Emergency Department & Public Health - Beyond the Basicsnickgenes
Emergency Departments (EDs) are the gateway to healthcare for the majority of Americans. There are over 125 million ED visits a year. One-third of these visits are due to injury, one-eighth to mental illness or substance abuse, and over one-third are from patients who are under- or un-insured. ED patients are often the members of society who are the most at-risk for poor health outcomes and also those with the fewest resources to address their acute or chronic medical conditions.
Yet ED patients have tremendous access to technology: recent studies show that despite low socioeconomic status, 95% of ED patients own cellphones, 93% access the internet, and 65% have smartphones. Technology provides potential solutions to perennial barriers to improving the health of the ED population, such as time constraints, access to post-ED care, and fidelity of interventions. And the ED patient population provides potential solutions to many perennial challenges for public health research: accessing difficult-to-reach populations, adequately sampling the most at-risk, and proving real-world efficacy.
This panel discussion will feature emergency physician-researchers, each of whom are currently conducting funded research on technology-based public health interventions. We will discuss the ways in which we have successfully stretched the boundaries of “Medicine 2.0” (interactive computer programs, text messaging, social media) to improve the health of the ED population. We will discuss ways to translate technology’s efficiency, efficacy and fidelity into the hectic ED environment. We will also outline some of the reasons to test mHealth innovations in the ED environment.
The use of mHealth to impact this at-risk population is imperative. Yet it is something that few researchers, computer scientists, pharmaceutical companies, mental health professionals, or hospital administrators have done. By the close of this panel discussion, attendees will have attained critical knowledge about the advantages of, and possibilities for, extending mHealth into the ED setting.
Panelists:
* Esther K. Choo, MD MPH, Assistant Professor of Emergency Medicine at Brown University, has grants from NIDA to develop interactive, computer-based interventions to address partner violence and substance use in the ED.
* Nick Genes, MD PhD is Assistant Professor of Emergency Medicine at Mt Sinai School of Medicine. Dr. Genes has spoken at national conferences on the utility of social media for physicians career development and ED community relations, and is researching physician usage of social media tools, HIT, and patient-support tools.
* Megan L Ranney, MD MPH is Assistant Professor of Emergency Medicine at Brown University, a core researcher in the Injury Prevention Center of Rhode Island Hospital. Her research includes using text-messaging to assess and deliver interventions to adolescent ED patients.
Scheduled to open in September 2012, St. Bernard Parish Hospital will bring quality healthcare back home to St. Bernard Parish. It also promises to serve as a catalyst for economic and community recovery in an area of Louisiana that was destroyed by Hurricane Katrina.
Principles And Practice Of Clinical Research Ap 2007Jyoti Batra
A very good book on clinical research. Includes everything from introducton to trials methodology etc..
A must read for clinical resaearch professional!!
Explore innovation and what fuels the fire for innovations. mHealth development, status and market opportunities for app developers. Learn why Innovating in mHealth will be an important market
Peter van Vooren (business developer at Remedus) and Bert Verbruggen (Project manager Verhaert) talk about the smartBEAT project. Verhaert innovation day 2015
HealthCursor Consulting Group India- Distribution and Marketing- Mobile network operators in Africa have identified the growing demand for financial services and micro insurance . Airtel Africa has partnered with MicroEnsure for Mobile Micro Insurance. The range of Airtel-branded insurance products includes life, accident, health, agriculture, and other forms of cover.
Connecting intermediaries, customers and surveyors- ICICI Lombard India's mobile initiative started simply enough, with a set of basic applications that gave customers a consolidated view of all their policies, a reminder service to renew a policy, and a way to track the status of a claim. But as they matured with the mobile platform, they re-visited the paradigm and devised new ways to provide customers with more value-added and user-friendly features. This is however restricted to Auto insurance only.
Encryption, Transactions and handling customer grievance- Public sector general insurance company United India Insurance launched a mobile-based real-time fund transfer facility for payment of premium. M-Power enables customers to renew their policies and also remit the premium for approved proposals. To use this facility, one has to get an MMID (an identification number called - mobile money identifier) from his/her bank and enable one’s mobile with the application given by the bank. However, there are only 10 banks on board with this platform. This initiative follows the launch of its Internet-based sales, customer grievance portal and information-cum-sales kiosks.
Sales, awareness and providing access- Bima, a young Swedish microinsurance company, is using mobile phones to sell as many as three billion new insurance policies to the global poor. Bima, that has begun to access this untapped market, is now one of the largest mobile insurance platforms in the world. In just three years, Bima has acquired 4 million clients in Africa and Asia and is adding 400,000 new subscribers per month. Bima has been tackling many of the obstacles—education, pricing, premium collection—that prevent poor people from obtaining such benefits. For instance, Bima products such as life, accident and health insurance cost "as little as $0.20 to $6.00 a month. Last month, Leapfrog invested $4.25 million in Bima, which will allow the company to expand even further within Africa and Asia as well as reach into new markets in Latin America.
MHealth or Mobile Health is an emerging and an innovative of medication in India, by doctors can communicate and treat their patients very conveniently even from far distances.
Analysis of the Innovation Outputs in mHealth for Patient MonitoringOresti Banos
In the last decade, mobile health (mHealth) has developed as a natural consequence of the advances in mobile technologies, the growing spread of mobile devices, and their application in the provision of novel health services. mHealth has demonstrated the potential to make the health care sector more efficient and sustainable and to increase the healthcare quality. Considering the boost to the healthcare area which will be provided by mHealth, many organizations and governments have engaged in innovating in this area. In this context, this work investigated the role of innovation in the area of mHealth for patient monitoring in order to determine the trends and the performance of the innovation activities in this domain. Proxy indicators, like intellectual property statistics and scientific publication statistics, were utilized to measure the outputs of innovation during the period of time from 2006 to 2015 in Europe. Two studies were performed to provide quantitative measures for the indicators measuring innovation outputs in the domain of mHealth for patient monitoring and three main conclusions were observed. First, even if there was a lot of research in Europe in mHealth for patient monitoring, the vast majority of the enterprises did not protect their inventions. Second, a strong research collaboration in the area of mHealth for patient monitoring took place between researchers affiliated to institu- tions of different European countries and even with researchers working in Asian or American institutions. Finally, an increasing trend on the number of published articles about mHealth for patient monitoring was identified. Therefore, the findings of the studies demonstrated the great interest that has arisen the field of mHealth and the huge involvement in innovation activities in the area of mHealth for patient monitoring.
Non Invasive Health Monitoring with mHealthBart Collet
mHealth Trends and examples of non invasive mobile health devices, organisations and services.
Made as preparation for MoMoAMS #14 about mHealth, Jan 25th 2010, Amsterdam
Self tracking, Sensors, and mHealth: Trends and Opportunitiesctorgan
Mobile health (mHealth) offers the perfect platform to merge self-tracking communities and sensor technologies. Toss in the power of social networking capabilities, and you've put the trifecta of instantaneous 'track, share, and compare' at people's fingertips.
Home health care & long-term conditions: How to succeed with personal health ...Mohammad Al-Ubaydli
Dr Mohammad Al-Ubaydli (CEO of Patients Know Best)
Dr Al-Ubaydli is author of the book "Personal health records: A guide for clinicians", in which he surveyed the different ways in which patients can work with their clinical team using software. A new generation of tools allows patients to manage their health and Mohammad will cover some of these in his talk, including products by large US companies like Google and Microsoft, as well as the UK software industry. He will also describe the experiences of his own company, Patients Know Best, which integrates its patient-controlled medical records platform into the NHS secure network.
Graeme Osborne
Director, National Health IT Board
Peter Gow
Chair, National Information Clinical Leadership Group
Ernie Newman
Chair, NHITB Consumer Panel
Barry Vryenhoek
Chief Executive, healthAlliance New Zealand Ltd
(Thursday, 9.45, Keynote)
Explore innovation and what fuels the fire for innovations. mHealth development, status and market opportunities for app developers. Learn why Innovating in mHealth will be an important market
Peter van Vooren (business developer at Remedus) and Bert Verbruggen (Project manager Verhaert) talk about the smartBEAT project. Verhaert innovation day 2015
HealthCursor Consulting Group India- Distribution and Marketing- Mobile network operators in Africa have identified the growing demand for financial services and micro insurance . Airtel Africa has partnered with MicroEnsure for Mobile Micro Insurance. The range of Airtel-branded insurance products includes life, accident, health, agriculture, and other forms of cover.
Connecting intermediaries, customers and surveyors- ICICI Lombard India's mobile initiative started simply enough, with a set of basic applications that gave customers a consolidated view of all their policies, a reminder service to renew a policy, and a way to track the status of a claim. But as they matured with the mobile platform, they re-visited the paradigm and devised new ways to provide customers with more value-added and user-friendly features. This is however restricted to Auto insurance only.
Encryption, Transactions and handling customer grievance- Public sector general insurance company United India Insurance launched a mobile-based real-time fund transfer facility for payment of premium. M-Power enables customers to renew their policies and also remit the premium for approved proposals. To use this facility, one has to get an MMID (an identification number called - mobile money identifier) from his/her bank and enable one’s mobile with the application given by the bank. However, there are only 10 banks on board with this platform. This initiative follows the launch of its Internet-based sales, customer grievance portal and information-cum-sales kiosks.
Sales, awareness and providing access- Bima, a young Swedish microinsurance company, is using mobile phones to sell as many as three billion new insurance policies to the global poor. Bima, that has begun to access this untapped market, is now one of the largest mobile insurance platforms in the world. In just three years, Bima has acquired 4 million clients in Africa and Asia and is adding 400,000 new subscribers per month. Bima has been tackling many of the obstacles—education, pricing, premium collection—that prevent poor people from obtaining such benefits. For instance, Bima products such as life, accident and health insurance cost "as little as $0.20 to $6.00 a month. Last month, Leapfrog invested $4.25 million in Bima, which will allow the company to expand even further within Africa and Asia as well as reach into new markets in Latin America.
MHealth or Mobile Health is an emerging and an innovative of medication in India, by doctors can communicate and treat their patients very conveniently even from far distances.
Analysis of the Innovation Outputs in mHealth for Patient MonitoringOresti Banos
In the last decade, mobile health (mHealth) has developed as a natural consequence of the advances in mobile technologies, the growing spread of mobile devices, and their application in the provision of novel health services. mHealth has demonstrated the potential to make the health care sector more efficient and sustainable and to increase the healthcare quality. Considering the boost to the healthcare area which will be provided by mHealth, many organizations and governments have engaged in innovating in this area. In this context, this work investigated the role of innovation in the area of mHealth for patient monitoring in order to determine the trends and the performance of the innovation activities in this domain. Proxy indicators, like intellectual property statistics and scientific publication statistics, were utilized to measure the outputs of innovation during the period of time from 2006 to 2015 in Europe. Two studies were performed to provide quantitative measures for the indicators measuring innovation outputs in the domain of mHealth for patient monitoring and three main conclusions were observed. First, even if there was a lot of research in Europe in mHealth for patient monitoring, the vast majority of the enterprises did not protect their inventions. Second, a strong research collaboration in the area of mHealth for patient monitoring took place between researchers affiliated to institu- tions of different European countries and even with researchers working in Asian or American institutions. Finally, an increasing trend on the number of published articles about mHealth for patient monitoring was identified. Therefore, the findings of the studies demonstrated the great interest that has arisen the field of mHealth and the huge involvement in innovation activities in the area of mHealth for patient monitoring.
Non Invasive Health Monitoring with mHealthBart Collet
mHealth Trends and examples of non invasive mobile health devices, organisations and services.
Made as preparation for MoMoAMS #14 about mHealth, Jan 25th 2010, Amsterdam
Self tracking, Sensors, and mHealth: Trends and Opportunitiesctorgan
Mobile health (mHealth) offers the perfect platform to merge self-tracking communities and sensor technologies. Toss in the power of social networking capabilities, and you've put the trifecta of instantaneous 'track, share, and compare' at people's fingertips.
Home health care & long-term conditions: How to succeed with personal health ...Mohammad Al-Ubaydli
Dr Mohammad Al-Ubaydli (CEO of Patients Know Best)
Dr Al-Ubaydli is author of the book "Personal health records: A guide for clinicians", in which he surveyed the different ways in which patients can work with their clinical team using software. A new generation of tools allows patients to manage their health and Mohammad will cover some of these in his talk, including products by large US companies like Google and Microsoft, as well as the UK software industry. He will also describe the experiences of his own company, Patients Know Best, which integrates its patient-controlled medical records platform into the NHS secure network.
Graeme Osborne
Director, National Health IT Board
Peter Gow
Chair, National Information Clinical Leadership Group
Ernie Newman
Chair, NHITB Consumer Panel
Barry Vryenhoek
Chief Executive, healthAlliance New Zealand Ltd
(Thursday, 9.45, Keynote)
Optimizing your EHR Value through Patient EngagementBrian Ahier
Focusing on the transformed healthcare system enabled by ARRA, hear ideas on how patients can help realize the value of your EHR and help you achieve meaningful use.
Judy Murphy, RN, FACMI, FHIMSS, FAAN
Deputy National Coordinator for Programs and Policy, Office of the National Coordinator for HIT
Ontology-Driven Clinical Intelligence: A Path from the Biobank to Cross-Disea...Remedy Informatics
The discovery of clinical insights through effective management and reuse of data requires several conditions to be optimized: Data need to be digital, data need to be structured, and data need to be standardized in terms of metadata and ontology. This presentation describes a bioinformatics system that combines a next-generation biobank management model mapped to applicable international standards and guidelines with a master ontology that controls all input and output and is able to add unique properties to meet the specialized needs of clinicians for cross-disease research.
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
Knee anatomy and clinical tests 2024.pdfvimalpl1234
This includes all relevant anatomy and clinical tests compiled from standard textbooks, Campbell,netter etc..It is comprehensive and best suited for orthopaedicians and orthopaedic residents.
CDSCO and Phamacovigilance {Regulatory body in India}NEHA GUPTA
The Central Drugs Standard Control Organization (CDSCO) is India's national regulatory body for pharmaceuticals and medical devices. Operating under the Directorate General of Health Services, Ministry of Health & Family Welfare, Government of India, the CDSCO is responsible for approving new drugs, conducting clinical trials, setting standards for drugs, controlling the quality of imported drugs, and coordinating the activities of State Drug Control Organizations by providing expert advice.
Pharmacovigilance, on the other hand, is the science and activities related to the detection, assessment, understanding, and prevention of adverse effects or any other drug-related problems. The primary aim of pharmacovigilance is to ensure the safety and efficacy of medicines, thereby protecting public health.
In India, pharmacovigilance activities are monitored by the Pharmacovigilance Programme of India (PvPI), which works closely with CDSCO to collect, analyze, and act upon data regarding adverse drug reactions (ADRs). Together, they play a critical role in ensuring that the benefits of drugs outweigh their risks, maintaining high standards of patient safety, and promoting the rational use of medicines.
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
New Drug Discovery and Development .....NEHA GUPTA
The "New Drug Discovery and Development" process involves the identification, design, testing, and manufacturing of novel pharmaceutical compounds with the aim of introducing new and improved treatments for various medical conditions. This comprehensive endeavor encompasses various stages, including target identification, preclinical studies, clinical trials, regulatory approval, and post-market surveillance. It involves multidisciplinary collaboration among scientists, researchers, clinicians, regulatory experts, and pharmaceutical companies to bring innovative therapies to market and address unmet medical needs.
Local Advanced Lung Cancer: Artificial Intelligence, Synergetics, Complex Sys...Oleg Kshivets
Overall life span (LS) was 1671.7±1721.6 days and cumulative 5YS reached 62.4%, 10 years – 50.4%, 20 years – 44.6%. 94 LCP lived more than 5 years without cancer (LS=2958.6±1723.6 days), 22 – more than 10 years (LS=5571±1841.8 days). 67 LCP died because of LC (LS=471.9±344 days). AT significantly improved 5YS (68% vs. 53.7%) (P=0.028 by log-rank test). Cox modeling displayed that 5YS of LCP significantly depended on: N0-N12, T3-4, blood cell circuit, cell ratio factors (ratio between cancer cells-CC and blood cells subpopulations), LC cell dynamics, recalcification time, heparin tolerance, prothrombin index, protein, AT, procedure type (P=0.000-0.031). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and N0-12 (rank=1), thrombocytes/CC (rank=2), segmented neutrophils/CC (3), eosinophils/CC (4), erythrocytes/CC (5), healthy cells/CC (6), lymphocytes/CC (7), stick neutrophils/CC (8), leucocytes/CC (9), monocytes/CC (10). Correct prediction of 5YS was 100% by neural networks computing (error=0.000; area under ROC curve=1.0).
Muktapishti is a traditional Ayurvedic preparation made from Shoditha Mukta (Purified Pearl), is believed to help regulate thyroid function and reduce symptoms of hyperthyroidism due to its cooling and balancing properties. Clinical evidence on its efficacy remains limited, necessitating further research to validate its therapeutic benefits.
These lecture slides, by Dr Sidra Arshad, offer a quick overview of the physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar lead (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
6. Describe the flow of current around the heart during the cardiac cycle
7. Discuss the placement and polarity of the leads of electrocardiograph
8. Describe the normal electrocardiograms recorded from the limb leads and explain the physiological basis of the different records that are obtained
9. Define mean electrical vector (axis) of the heart and give the normal range
10. Define the mean QRS vector
11. Describe the axes of leads (hexagonal reference system)
12. Comprehend the vectorial analysis of the normal ECG
13. Determine the mean electrical axis of the ventricular QRS and appreciate the mean axis deviation
14. Explain the concepts of current of injury, J point, and their significance
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. Chapter 3, Cardiology Explained, https://www.ncbi.nlm.nih.gov/books/NBK2214/
7. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
263778731218 Abortion Clinic /Pills In Harare ,sisternakatoto
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These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
10. First Speaker:
Dr Mohammed Al-Ubaydli
In 2008, Mohammed founded Patients Know Best, a
website that gives patients online access to their
medical data. Mohammad has over 15 years of
experience in medical software. He trained as a
physician at the University of Cambridge; worked as a
staff scientist at the National Institutes of Health; and
was a management consultant to US hospitals at The
Advisory Board Company. Patients Know Best was
featured in Wired magazine’s March 2011 issue.
12. Women’s suffrage over time
Source:
h*p://en.wikipedia.org/wiki/Timeline_of_women's_suffrage
13. Women’s suffrage over time
Professionals objecting to patient control
are like Swiss men objecting to women
voting in 1971: wealthy, civilized,
eloquent… and on the wrong side of
history
14. A bit about me…
Trained as physician at the
University of Cambridge.
Trained as programmer and
worked as NIH Staff Scientist.
Honourary Senior Research
Associate, UCL Medical
School.
Continuing research on PHRs
from 2,700 US hospitals, new
book in 2010:
book.patientsknowbest.com
15. Our customers
Use our platform to save money from
shared workflow
1. Thalidomide Trust / Imperial College
hospital wanted us for online
consultations
2. Great Ormond Street hospital
wanted us for home health care
electronic prescribing
3. More clinicians joining every day as
patients invite them to
We can do what Microsoft, Google and
the NHS cannot do
16. PKB is the only option for patient-
controlled medical records
We will put patients in charge of making decisions about their
care, including control of their health records
The Coalition:our programme for government, Cabinet Office,
2010.
http://programmeforgovernment.hmg.gov.uk/nhs
26. Roadmap
1. Basics: definitions, and why do this
at all?
2. Today: letting go of assumptions
3. Tomorrow: embracing possibilities
27. Some definitions
Clinicians Patient
Personal health
Electronic patient records Patient portals Personal records
records
28. Some definitions
Clinicians Patient
Personal health
Electronic patient records Patient portals Personal records
records
Data by clinicians
for clinicians
29. Some definitions
Clinicians Patient
Personal health
Electronic patient records Patient portals Personal records
records
Easing the patient’s burden
Scheduling appointments
Ordering medication refills
Secure messaging
Access to the EPR
See: Pyer et. al 2004, Ralston et. al 2007.
30. Some definitions
Clinicians Patient
Personal health
Electronic patient records Patient portals Personal records
records
Data by patient for patient
Powerful but unstructured
NHSmail users have mailbox shrunk
06 Feb 2008
NHS staff who use the health service’s email service NHSmail have been informed
that after a recent move to Microsoft Exchange their mailbox size has been capped.
Some 80% of NHS accounts have been capped at just 200Mb, which
appears miserly compared with the hefty 6Gb offered by Gmail for free, or
the 5Gb offered for free on Windows Live Hotmail.
31. Some definitions
Clinicians Patient
Personal health
Electronic patient records Patient portals Personal records
records
Markle Foundation’s ideal
PHR:
Access controlled by patient
Lifelong records
Information from all
Universal access
Private and secure
Transparent
Easy exchange
See: Connecting for Health, 2004
32. Roadmap
1. Basics: definitions, and why do this at all?
2. Today: letting go of assumptions
3. Tomorrow: embracing possibilities
33. Patient-held records already here
Some parts of some health systems have already
had them
In continental Europe and much of developing world, this is the norm
UK private health care, and US fragmented care, patients end up doing this
anyway
NHS maternal notes and child personal health record use the patient to
cross silos
Distribution is arbitrary, but users assume
otherwise
34. Conflict is gone
Discomfort clinicians feel is due to limitations of
paper
Piece of paper cannot be in two places at the same time
Transporting paper takes time and money
Clinicians do not feel safe unless they hold the only copy of the paper
Digital records eliminate the conflict
35. Patient-controlled records awesome
This is the only way to bridge the silos
Within “integrated” systems like NHS and Kaiser Permanente, clinicians do
not talk to each other across community and hospitals
Within single institution e.g. hospital, clinicians do not talk to each other
across departments
Within same department, clinicians do not talk to each other across
specialities
The patient is the only person who turns up to all
the appointments, so give them the records
36. Patients should manage their clinicians
Unique patients require truly patient-centred care
In a rare chronic disease, the patient knows more than most of the clinicians
they meet
There are 30 million people with rare diseases in Western Europe and the
USA
But even patients with common diseases have unique combinations of
diseases and circumstances
Every patient is unique
37. Roadmap
1. Basics: definitions, and why do this at all?
2. Today: letting go of assumptions
3. Tomorrow: embracing possibilities
43. Patients will collect data you never knew
Useful web sites
Patients Like Me for HIV: patientslikeme.com
23andMe for genetic sequencing:
23andme.com
RelifeInSite for pain documentation:
reliefinsite.com
Lifepsychol for monitor quality of life:
lifepsychol.com
Personal health records: A guide for clinicians
Al-Ubaydli, 2011, John Wiley & Sons
http://book.patientsknowbest.com
44. Patient-reported outcomes /
observations / information
Patient-controlled records as a research tool
Patient-reported outcomes on each consultation
Patient-reported observations on data that had never previously been collected in medical
records
Patient-reported information through sentiment analysis of diaries
45. Mohammad Al-Ubaydli
Patients Know Best
team@patientsknowbest.co
m
www.patientsknowbest.com
Thank you for listening
46. First Demo:
Dr Henry Lee
Henry Lee is training as a Surgeon in
London and studied medicine at the
University of Wales College of Medicine.
He holds an academic post at Imperial
College London and is researching the way
that measure of wellbeing can be used for
policy purposes.
47.
48.
49.
50.
51.
52.
53.
54.
55. Second Demo:
Dr David Aanensen
David Aanensen is a bioinformatician in the School of
Public Health, Imperial College London. His research
focus is on the use and development of web
applications for infectious disease microbiology.
56. EpiCollect
Dr
David
Aanensen
Dept.
Infec>ous
Disease
Epidemiology
Imperial
College
London
58. Bd-‐Maps
• Bd
is
a
fungal
pathogen
causing
wide-‐spread
amphibian
mortality.
• Demands
colla>on
of
cases
of
disease.
• Communi>es
of
scien>sts
submit
data.
h*p://www.bd-‐maps.net
59.
60.
61.
62.
63.
64. EpiCollect
-‐
Smartphones
for
data
collec>on
• GPS
–
loca>on
aware
• Cameras
for
s>lls
or
videos
• Keyboards
for
text
entry
• Data
transfer
to
/
from
central
databases.
Aanensen
et
al
(2009)
PLoS
ONE
4(9):
e6968
65. h*p://www.epicollect.net
• Generic
issue
–
mobile
data
collec>on
• Any
projects
where
centralising
textual
data
along
with
GPS
and
/
or
photos/media
from
many
different
people,
from
many
different
places,
would
be
useful.
67. h*p://www.epicollect.net
Create
a
Project
Design
a
form
for
Load
Project
into
the
View
data
collected
website
at
data
collec>on
EpiCollect
mobile
app
at
your
project
EpiCollect.net
and
collect
data,
website
or
on
your
including
GPS
posi>on
phone
(download,
and
photo
view
on
maps/
charts,
filter.)
68.
69.
70.
71.
72.
73.
74.
75.
76.
77.
78.
79.
80.
81.
82.
83.
84.
85.
86.
87. Ci>zen
data
collec>on
• Yellowstone
na>onal
Park
• 3,472
sq
m
visited
by
thousands
of
people
each
year.
• Currently
undertaking
projects
to
allow
members
of
the
public
to
aid
researchers
in
iden>fica>on
and
mapping
of
invasive
plant
species.
88. Archaeological
dig
sites
Dig
sites
across
Europe
Pre
–
major
building
works
Replacing
paper
forms
for
linking
and
mapping
areas
of
dig
sites.
89. Street
art*
• Categorised
by
type
–
eg
posters,
s>ckers,
stencils
etc.
*Disclaimer:
probably
not
to
be
encouraged…
90. Animal
Health
surveillance
in
Kenya
/
Tanzania
Maasai
vets
Carry
out
Disease
Surveillance
of
86,000
animals
with
Google
Mobile
phones
Ongoing
monitoring
of:
East
Coast
Fever;
anthrax
and
rabies;
FMD
Gabriel
Turasha
(Vetaid
Tanzania)
Nick
Short
(RVC)
and
Niall
Winters(IOE)
91. • No
reliance
on
data
networks
for
collec>on.
• Data
can
be
sent
to
any
server.
• Two-‐way
data
transfer
• Simple
XML
descrip>on
of
project
forms
and
for
defini>on
of
server
loca>ons.
92. Acknowledgements
• Dr
Derek
Huntley,
Jon
Evans,
Chris
Powell,
Prof.
Brian
Spra*
d.aanensen@imperial.ac.uk
Funded
by:
93. Second Speaker:
Dr Adesina Iluyemi
Adesina is an executive board member and a co-chair of the
Global Health Commission of the NEPAD Council, a non-profit
organization. His expertise lies in mHealth and Telemedicine
innovation and policy development. He has in the past
collaborated with influential international multilateral,
organizations such as the WHO, UN, ITU, and the
Commonwealth Secretariat. He is a Fellow and Council
member Telemed & eHealth Section of the RSM England, and
a co-founder and executive director of MODISE; an initiative
working to bring low-cost connected mobile diagnostics to
developing countries.
95. An Overview
USERS CASES
CITIZENS (Consumers, Patients) Call Centre models
TeleDoc, Pakistan
COMMUNITY (Population) SMS Casting Model
Masiluleke, South Africa
CLINICIANS (Health Workers) Mobile Telemedicine, Botswana
CENTRES ( Facilities) Mobile Microscopy e.g LUCAS
Source:
Author
• Need
to
move
Beyond
SMS!
• Clinicians
&
Centres
offer
be*er
Commercial
Opportuni>es
Sustainable Serendipitous Situated
96. Voice & SMS, few Data Apps
Cell-‐Life
Sustainable Serendipitous Situated Page
96
99. Mobile + Medical Renaissance
• Teleradiology
• Remote
Imaging
• Laboratory
Detec>on
• Clinical
Diagnosis
• Rural
Healthcare
• Emergency
Medicine
• Pandemics
• Epidemics
• Point
of
Care
Diagnos>cs
OPPORTUNITY
FOR
LOW-‐COST
INOVATIONS
IN
DEVELOPING
COUNTRIES
Sustainable Serendipitous Situated
100. Medical Innovations 1
•
Medical
Devices/
Mobile
Microscopy
e.g
LUCAS,
CellScope
• Assis>ve
Technology?
e.g
NETRA
for
remote
eye
examina>on
• Mobile
EHR
e.g
mGEOs
with
geotagging
and
web-‐interface
UCLA
2009
Sustainable Serendipitous Situated
101. Medical
Innova>on
2
• Mobile
Telemedicine
e.g
Click
Diagnos>cs
for
skin
&
oral
lesions
and
cervical
screening
in
Botswana
•
Real
Pa>ent
Monitoring
e.g
A
pilot
with
a
Private
Hospital
in
Nigeria
• Medical
Apps
e.g
Moodle4iPhone
pilots
using
Android
&
iPhonein
Peru
Sustainable Serendipitous Situated
102. Introducing
MoDiSe
MISSION: Collaborate with
private sector innovators /
biotechnology
researchers and local
entrepreneurs to facilitate the
development of Point of Care tools
to prevent, diagnose and treat
neglected tropical and
non-communicable
diseases in the developing
world-
www.modise.org
Non-for-Profit Organization
in Canada
Sustainable Serendipitous Situated
103. MoDiSe: Our Strategy
Mobile
Diagnos>cs
for
Global
Health
h*p://www.modise.org
Sustainable Serendipitous Situated
6/7/11
MoDiSe
106. ThinkCamp was brought to you by:
We are an ‘idea-to-launch’ community platform for the collaborative
development of mobile applications, products & services across many
industries. (More than just apps – think personal mobility services, mHealth
applications, SIM-card embedded devices, sensory data meets cloud
computing, and SMS-based solutions in the developing world).
We bring the mobile developer & designer community together with members
of professional communities, such as healthcare; facilitate the sharing of
experiences, insights and skills; and provide a structure for developing and
acting on the innovative ideas that emerge. We do this by running a series of
ThinkCamp events which take a collaborative approach to generating and
developing good ideas. Adhoc teams which form around the ideas are
supported & nurtured by a wide range of participating technologists, field
experts and market channel partners to implement a solution or turn turn the
developed proposition into a commercially viable product or service. Our first
area of focus is mHealth.
Over time we will also build an online collaboration community for idea
development that provides a supportive process all the way to
implementation. The business model for all who get involved is joint venture /
revenue share
@mobilecollectiv
107. ThinkCamp was made possible with the support of our partners:
With thanks also to:
Editor's Notes
Teams of scientists in the field
This kind of community approach. Scientists can get together and take advantage of modern tools to enable concurrent submission and analysis of data. Community of scientists – extending out to get community involved in such projects and beyond (such as the flutracker project)