MariaDB is an open-source database that is highly tunable and modular. It allows for various storage engines, plugins, and configurations to optimize performance depending on usage. Key aspects that impact performance include memory allocation, disk access, query optimization, and architecture choices like replication, sharding, or using ColumnStore for analytics. Solutions like MyRocks, Spider, MaxScale can improve performance for transactional or large scale workloads by optimizing resources, adding high availability, and distributing load.