Intelligent Health Lab
Kenneth D. Mandl, MD, MPH
Director, Intelligent Health Laboratory
Children’s Hospital Informatics Program
Center for Biomedical Informatics, Harvard
The App Store for Health:
Co-opting the Point of Care
in the Era of the Affordable Care Act
Intelligent Health Lab
US Spending per capita vs. Life Expectancy
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Learning Health System: Evidence Generated
from a Well-Instrumented Health System
Intelligent Health Lab
? How do we learn from
“All the Patients . . .
All the Time?”
(Instead of Some of the
Patients All of the Time . . . )
. . . or really, just a couple of
the patients, not that often.
Intelligent Health Lab
Intelligent Health Lab
Dr. Collins discussing the
Rapid Learning Network
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WITHOUT ACCESS TO THE
POINT OF CARE,
EVERYTHING IS A ONE-OFF
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Intelligent Health Laboratory | Children‘s Hospital Informatics
Program
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Returning Genomic Medicine Results
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Intelligent Health Lab
The App Store for Health
ONC Funded Research $15M Project under the
“SHARP” program
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Can EMRs behave
like iPhones or
Androids in that
innovators
readily create and
widely distribute
apps across
thousands of
installs?
Intelligent Health Lab
Our vocabulary
 Data Sources
Managed by containers
 Containers
Present data from data sources to apps in a uniform 
fashion
 Apps
Completely substitutable
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18.12 Issue
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State-of-the-Art ???
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Intelligent Health Lab
1 Design + 1 Developer + 1 Week
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1 SMART App in 3 SMART Systems
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Well-publicized
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Intelligent Health Lab
SMART
BP Centiles App
Running on Cerner
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Intelligent Health Lab
Medication adherence
JAMIA 2011
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Intelligent Health Lab
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26
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Decision Support Integration
e.g., Immunization Forecasting
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Monograph app
e.g., Diabetes
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Mashups:
e.g., Genomic Medicine: There’s an App for that
 Linkage to external
decision support
services
 Pharmacogenomic
rule sets
 Decision support
for doctors—
associations
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Collaborators and Implementers
 EMR Vendors
 Payors
 Pharma
 Major tech companies complementing or competing
in the EHR space
 Large-scale health systems
Intelligent Health Lab

Mandl app store for health