Glaucoma

1. Male Reproductive System
Pathology

2. Penile Diseases
1. Congenital malformations
 Hypospadias is Ventral orifice
 Epispadias is dorsal orifice
 Phymosis is small prepuce orifice

3. ...

4. Penile Diseases
2. Inflammations
STDs
 Balanitis- Inflammation of the glans penis
 Orchitis- Is inflammation of one or both testicles
3. Tumors
 Benign : Condyloma accuminatum (HPV)
 Malignant
o Ca insitu ( bowen disease)
o Squamous cell Ca (HPV 16, 18)

5. Question!
13. Which is benign?
A. Condyloma accuminatum
B. Ca insitu
C. Squamous cell Ca
D. None

6. …

7. Testes and Epididymis
• Congenital : Cryptorchidism (clinical
importance??)
• Atrophy : causes and effects
• Inflammation : Epydidymo-orchitis
• Causes:
• Clinical features
• Testicular Torsion:
• Testicular Tumors

8. Causes of Scrotal Swelling
 Testicular tumors
 Testicular infections( mumps, TB)
 Testicular torsion
 Hernia
 Varicocele
 Hydrocele

9. Varicocele
 Is an enlargement of the veins in the testicles due to
an abnormal blood flow.
Hydrocele
 Is the presence of fluid in the scrotum, which function
is to allow testicular mobility and to absorb the shocks.
 A hydrocele is commonly caused by inflammation of
the testes.

10. Testicular Tumors
WHO Classification
Single Histogenic
Tumors(40%)
Seminomas (30%)
Teratoma
Embryonal Carcinoma
Yolk Sac Tumor
Choriocarcinoma
Sex cord Tumors
Combined
Tumors(60%)
MIXED

11. Seminoma
 Is the most common (30%)
 Age 20 – 30 years
 Clinically : painless lobulated swelling
 Histologically :
o Large clear cells with central Nuclei
o Fibrous stroma
o lymphocytic infiltrate
 Diagnosis

12. Seminoma

13. Disorders of Prostate
Prostatitis
o Acute bacterial
o Chronic bacterial
o Chronic abacterial
Benign Nodular Hyperplasia
Ca Prostate

14. BPH
 Very common in old males
Pathogenesis
 Increased DHT and estrogen
Clinically
 Urine retention
 Frequency, nocturia, UTI
 Bladder hypertrophy
Pathology
 Middle lobe nodularity,↑↑ glands +
fibromuscular stroma

15. …
BPH Ca Prostate

16. Prostate Ca
 Most common male cancer
 2nd causes of male cancer death
 65- 75 years
Pathogenesis
 Hormonal
 Environmental
 Genetic bases

17. Question!
14. Is the most common & 2nd causes of cancer death in female
A. Breast cancer
B. Lung cancer
C. Colorectal cancer
D. Prostate cancer
15. Is 1st causes of cancer death in female
A. Lung cancer
A. Colorectal cancer
B. Breast cancer
C. Cervical cancer
D. Skin cancer

18. Question!
16. Is the 1st causes of cancer death in male
A. Lung cancer
B. Prostate cancer
C. Colorectal cancer
D. Skin cancer
17. Is the most common & the 2nd causes of male cancer death
A. Prostate cancer
B. Lung cancer
C. Colorectal cancer
D. Gastric cancer

19. Question!
18. Is the 4th most common cancer among women globally
A. Breast cancer
B. Cervical cancer
C. Colorectal cancer
D. Lung cancer

20. Clinical /f
• local
• General
Pathology
Macro: ... Site . Shape , color ,..
Micro: Adenocarcinoma

21. URETHRA
PERIPHERAL
ZONE
NORMAL
BNH CARCINOMA

23. Diagnosis
• Clinical
• Radioolgical
• Lab
- routine
- FNA , true-cut, biopsy
- tumor markers

24. Prostatic biopsy