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MAKING SENSE
OUT OF SCIENCE




          April 17, 2007
WHERE HAVE I COME FROM -
     ACADEMICALLY SPEAKING!
• Honours BSc Guelph
• Accelerated PhD (4.5 years)
   – Department of Medical Biophysics U of T
   – Drug metabolism
• Post-Doctoral Fellowship (3 years)
   – p53 with David Lane, University of Dundee, Scotland
• Post-Doctoral Fellowship (2 years)
   – Telomerase with Silvia Bacchetti, McMaster University
DECISION POINTS
• BSc to where?
   – Enjoyed the lab, natural leader
     (poor follower)
   – Encouraged to do PhD
   – Accepted at OCI


PhD to where?
   – Enjoyed the lab
   – Managed the lab
   – President of Student Executive
   – Held NCI studentships
   – Become a PI - future likely Pharma
ACADEMIA IN CANADA IS NOT FOR ME

       WHERE TO NEXT?
DECISION POINT
BIOTECHNOLOGY in 2000

• Industry booming
• Young and dynamic –fun
• Excellent growth opportunities
• Good money, stock options, bonuses
• Like academia – but with lots of $$$
• No grant applications
MDS Proteomics

                 Scientist
                     !
        Manager Molecular Biology
                      !
         Liaison to CSO/ IP Licensing/
    Bioinformatics/Scientist Special Projects
DECISION POINT
• Industry busting
• Everyone’s position uncertain- mood dark – money tight


             WHERE TO NEXT?


• Biotech? Pharma? Service Industry?
• Bench Scientist? Clinical? Regulatory? Communications?
acne
                                           moisturizers

                                  eczema


                                           skin barrier


cleansers



   skin infections

                      skin infestations

ingredients matter
BONNIE KUEHL –
SCIENTIST/CONSULTANT

! Research to address biological questions
! Write white papers
! Write scientific articles
! Assist with writing consumer information
! Assist with writing physician information
BONNIE KUEHL –
SCIENTIST/CONSULTANT
• Network
• Ask questions of industry people
   – MBA?
   – Biotech?
   – Pharma?
• Business Course


       Lack of affiliation quot; lack of credibility
   !
BONNIE KUEHL –
SCIENTIST/CONSULTANT
SKILLS
   – PhD
   – Excellent communicator
   – Outgoing
   – Like to NETWORK
   – Stubborn – don’t give up
   – Understanding of business
     development
   – Understanding of IP
   – Understanding of management mindset
   – Understanding of marketing
Scientific Insights Consulting Group
• Scientific Consultant to Service
  Industry and Pharma
   – August 2002

UPSIDE
      • Mine
      • I’m the boss
      • Follow personal objectives/goals
      • Business skills – growth
        opportunity
      • Experience
      • Choices
Scientific Insights Consulting Group

• DOWNSIDE
    • Age
    • Scientific experience (only 10 years post-BSc)
    • No longer a scientist
    • Business experience (minimal)
    • Limited connections outside of Biotech
    • Lack of Focus – Jack of all Trades
    • Every project a learning experience
    • No $ safety net
WHAT DOES
SCIENTIFIC INSIGHTS®
        DO?
Transdermal Drug Delivery
         Stratum Corneum/Skin Barrier
• fluid interaction: corneocytes, lipids and natural
  moisturizing factors.

• corneocytes cluster together
  in groups of 2-10 cells




• lipids fill the spaces between the cells forming lamellar
  bilayers
• Three routes: transcellular, lipid partitioning,
                     transappendageal
WHAT WE CAN’T SHOW YOU!
  • White papers
  • Industry reports
  • FDA submissions
  • Clinical reports
  • Training material for sales and marketing groups
  • Professional slide kits
  • Newsletters
  • Advisory Board Reports
  • And more…….
WHAT DOES SCIENTIFIC INSIGHTS® DO?

        COMMUNICATES
        TEACHES
        EDUCATES
        TRANSLATES
        DIRECTS/GUIDES
        CONNECTS
WHAT HAVE I/ WE LEARNED
   ABOUT BUSINESS?
Believe it or NOT

• IT is all about NETWORKING
    Who you know
    Who you know
    Who you know knows


  Life/Work/Business is all about
    MARKETING yourself and your skills
STARTING UP!
• Branding
    – Name
    – Logo
• Office
   – Telephone/fax/ e-mail
   – Paper/ files
• Marketing materials
   – Website
   – Business cards
   – Pamphlets
• Visibility
    – Networking
    – Word of mouth
    – Referrals
    – Cold calls
YOU CAN’T DO IT ALONE -TEAMWORK

      • Friends and Family
      • Bookkeeping
      • Administration
      • Child care
      • Graphic Design
      • Marketing
      • Web support
      • Bank
      • Cleaning
MENTORS - EXPERIENCED VOICES
• Identify your weaknesses
• Ask questions
• Every encounter is a learning opportunity
• Ask questions
• Admit you don’t have a clue
• Be open to trying and learning different things
• Learn to ask for help
• Ask questions

   ! LEARN TO STRECH YOURSELF
YOU CAN’T DO IT ALONE -TEAMWORK
Scientific Insights® Consulting Group Inc.
   •   Partner
   •   Friends and Family
   •   Lawyer
   •   Bookkeeper
                            Scientific Insights®
   •   Accountant
   •   Administration             I OWN IT!!!
   •   Child care
   •   Graphic Design
   •   Marketing
   •   Web support
   •   Bank – investment
   •   Insurance
   •   Cleaning
GREATEST CHALLENGES

• What to charge?
• Asking for the project –closing the sale
• Invoicing and collecting money
• Prioritizing jobs
• Getting the work done – wearing too many hats
• Juggling projects
GREATEST CHALLENGES
• Client / project strategy and objectives
   – Understanding where they are going
   – Persuading on best next steps



• CHOICES
   – Family
   – Clients
   – Networking
   – Volunteering
GROWTH

• More brains –
  more projects
• More hands on deck
• Good turnaround
• Greater diversity
   – Team
   – Projects
• Larger client base
EVERY ENCOUNTER IS A
BUSINESS OPPORTUNITY
PLACES TO BE SEEN

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Making Sense Out of Science

  • 1. MAKING SENSE OUT OF SCIENCE April 17, 2007
  • 2. WHERE HAVE I COME FROM - ACADEMICALLY SPEAKING! • Honours BSc Guelph • Accelerated PhD (4.5 years) – Department of Medical Biophysics U of T – Drug metabolism • Post-Doctoral Fellowship (3 years) – p53 with David Lane, University of Dundee, Scotland • Post-Doctoral Fellowship (2 years) – Telomerase with Silvia Bacchetti, McMaster University
  • 3. DECISION POINTS • BSc to where? – Enjoyed the lab, natural leader (poor follower) – Encouraged to do PhD – Accepted at OCI PhD to where? – Enjoyed the lab – Managed the lab – President of Student Executive – Held NCI studentships – Become a PI - future likely Pharma
  • 4. ACADEMIA IN CANADA IS NOT FOR ME WHERE TO NEXT?
  • 6. BIOTECHNOLOGY in 2000 • Industry booming • Young and dynamic –fun • Excellent growth opportunities • Good money, stock options, bonuses • Like academia – but with lots of $$$ • No grant applications
  • 7. MDS Proteomics Scientist ! Manager Molecular Biology ! Liaison to CSO/ IP Licensing/ Bioinformatics/Scientist Special Projects
  • 8. DECISION POINT • Industry busting • Everyone’s position uncertain- mood dark – money tight WHERE TO NEXT? • Biotech? Pharma? Service Industry? • Bench Scientist? Clinical? Regulatory? Communications?
  • 9. acne moisturizers eczema skin barrier cleansers skin infections skin infestations ingredients matter
  • 10. BONNIE KUEHL – SCIENTIST/CONSULTANT ! Research to address biological questions ! Write white papers ! Write scientific articles ! Assist with writing consumer information ! Assist with writing physician information
  • 11. BONNIE KUEHL – SCIENTIST/CONSULTANT • Network • Ask questions of industry people – MBA? – Biotech? – Pharma? • Business Course Lack of affiliation quot; lack of credibility !
  • 12. BONNIE KUEHL – SCIENTIST/CONSULTANT SKILLS – PhD – Excellent communicator – Outgoing – Like to NETWORK – Stubborn – don’t give up – Understanding of business development – Understanding of IP – Understanding of management mindset – Understanding of marketing
  • 13. Scientific Insights Consulting Group • Scientific Consultant to Service Industry and Pharma – August 2002 UPSIDE • Mine • I’m the boss • Follow personal objectives/goals • Business skills – growth opportunity • Experience • Choices
  • 14. Scientific Insights Consulting Group • DOWNSIDE • Age • Scientific experience (only 10 years post-BSc) • No longer a scientist • Business experience (minimal) • Limited connections outside of Biotech • Lack of Focus – Jack of all Trades • Every project a learning experience • No $ safety net
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  • 24. Transdermal Drug Delivery Stratum Corneum/Skin Barrier • fluid interaction: corneocytes, lipids and natural moisturizing factors. • corneocytes cluster together in groups of 2-10 cells • lipids fill the spaces between the cells forming lamellar bilayers • Three routes: transcellular, lipid partitioning, transappendageal
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  • 26. WHAT WE CAN’T SHOW YOU! • White papers • Industry reports • FDA submissions • Clinical reports • Training material for sales and marketing groups • Professional slide kits • Newsletters • Advisory Board Reports • And more…….
  • 27. WHAT DOES SCIENTIFIC INSIGHTS® DO? COMMUNICATES TEACHES EDUCATES TRANSLATES DIRECTS/GUIDES CONNECTS
  • 28. WHAT HAVE I/ WE LEARNED ABOUT BUSINESS?
  • 29. Believe it or NOT • IT is all about NETWORKING Who you know Who you know Who you know knows Life/Work/Business is all about MARKETING yourself and your skills
  • 30. STARTING UP! • Branding – Name – Logo • Office – Telephone/fax/ e-mail – Paper/ files • Marketing materials – Website – Business cards – Pamphlets • Visibility – Networking – Word of mouth – Referrals – Cold calls
  • 31. YOU CAN’T DO IT ALONE -TEAMWORK • Friends and Family • Bookkeeping • Administration • Child care • Graphic Design • Marketing • Web support • Bank • Cleaning
  • 32. MENTORS - EXPERIENCED VOICES • Identify your weaknesses • Ask questions • Every encounter is a learning opportunity • Ask questions • Admit you don’t have a clue • Be open to trying and learning different things • Learn to ask for help • Ask questions ! LEARN TO STRECH YOURSELF
  • 33. YOU CAN’T DO IT ALONE -TEAMWORK
  • 34. Scientific Insights® Consulting Group Inc. • Partner • Friends and Family • Lawyer • Bookkeeper Scientific Insights® • Accountant • Administration I OWN IT!!! • Child care • Graphic Design • Marketing • Web support • Bank – investment • Insurance • Cleaning
  • 35. GREATEST CHALLENGES • What to charge? • Asking for the project –closing the sale • Invoicing and collecting money • Prioritizing jobs • Getting the work done – wearing too many hats • Juggling projects
  • 36. GREATEST CHALLENGES • Client / project strategy and objectives – Understanding where they are going – Persuading on best next steps • CHOICES – Family – Clients – Networking – Volunteering
  • 37. GROWTH • More brains – more projects • More hands on deck • Good turnaround • Greater diversity – Team – Projects • Larger client base
  • 38. EVERY ENCOUNTER IS A BUSINESS OPPORTUNITY