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Making evidence accessible to clinicians Dr Charles Young Editor,  BMJ Clinical Evidence
Why bother? ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Practical versus Conceptual conceptual access practical
Progress
Practical issues Haynes RB, ACP J Club 2006; 145(3):A8
Why publish the full paper? ,[object Object],Smith R. BMJ  2004;328 (19 June), doi:10.1136/bmj.328.7454.0-h
But…… ,[object Object],Gøtzsche P C. BMJ  2006;333:231-234 (29 July), doi:10.1136/bmj.38895.410451.79
Progress
Practical issues Haynes RB, ACP J Club 2006; 145(3):A8
Words, numbers, or pictures? Authors' conclusions The small number of randomised controlled trials, together with the poor methodological quality and significant clinical heterogeneity, means that the current evidence is not sufficiently extensive or rigorous to support the use of any form of acupuncture for the treatment of insomnia. Larger high quality clinical trials employing appropriate randomisation concealment and blinding with longer follow-up are needed to further investigate the efficacy and safety of acupuncture for the treatment of insomnia. Sleep quality (primary outcome) Two studies reported an outcome of post-treatment sleep quality ( Tsay  2003 ;  Tsay  2004 ) that was better in the treatment group, and the combined result reached statistical significance ( SMD = -0.55, 95% CI = -0.89 to -0.21, p=0.002 ) (Figure 01.03). A change in sleep quality score was reported by  Chen 1999  that was significantly better in the treatment group ( SMD = -2.49, 95% CI = -3.20 to -1.78, p<0.00001 ) (Figure 01.04). Cheuk D, Yeung W, Chung K, Wong V. Cochrane Database Syst Rev. 2007 Jul 18;(3):CD005472.
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Doubt
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Doubt
GRADE - categories ,[object Object],[object Object],[object Object],[object Object]
GRADE - components ,[object Object],[object Object],[object Object],[object Object],[object Object]
GRADE
GRADE
GRADE
Updating ,[object Object],[object Object],[object Object]
St Thomas’ Hospital ED
St Thomas’ ED
Integration
Integration
Practical versus Conceptual conceptual access practical
Spot the odd one out? ‘ Drug 'ends need for mastectomy’ ‘ Herceptin eradicates aggressive tumors: study’
Conclusion ,[object Object],[object Object],[object Object]

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Making Evidence Accessible to Clinicians Reduces Antibiotic Use

  • 1. Making evidence accessible to clinicians Dr Charles Young Editor, BMJ Clinical Evidence
  • 2.
  • 3. Practical versus Conceptual conceptual access practical
  • 5. Practical issues Haynes RB, ACP J Club 2006; 145(3):A8
  • 6.
  • 7.
  • 9. Practical issues Haynes RB, ACP J Club 2006; 145(3):A8
  • 10. Words, numbers, or pictures? Authors' conclusions The small number of randomised controlled trials, together with the poor methodological quality and significant clinical heterogeneity, means that the current evidence is not sufficiently extensive or rigorous to support the use of any form of acupuncture for the treatment of insomnia. Larger high quality clinical trials employing appropriate randomisation concealment and blinding with longer follow-up are needed to further investigate the efficacy and safety of acupuncture for the treatment of insomnia. Sleep quality (primary outcome) Two studies reported an outcome of post-treatment sleep quality ( Tsay 2003 ; Tsay 2004 ) that was better in the treatment group, and the combined result reached statistical significance ( SMD = -0.55, 95% CI = -0.89 to -0.21, p=0.002 ) (Figure 01.03). A change in sleep quality score was reported by Chen 1999 that was significantly better in the treatment group ( SMD = -2.49, 95% CI = -3.20 to -1.78, p<0.00001 ) (Figure 01.04). Cheuk D, Yeung W, Chung K, Wong V. Cochrane Database Syst Rev. 2007 Jul 18;(3):CD005472.
  • 11. Doubt
  • 12. Doubt
  • 13. Doubt
  • 14. Doubt
  • 15. Doubt
  • 16.
  • 17.
  • 18. GRADE
  • 19. GRADE
  • 20. GRADE
  • 21.
  • 26. Practical versus Conceptual conceptual access practical
  • 27. Spot the odd one out? ‘ Drug 'ends need for mastectomy’ ‘ Herceptin eradicates aggressive tumors: study’
  • 28.