This document provides instructions for creating a simple HL7 sender and receiver project using OpenESB. It describes how to create BPEL projects to poll for HL7 messages from a file system and send them over MLLP to an external system. It also covers creating a BPEL project to receive HL7 messages over MLLP, convert them to XML, and write them to a file. Composite application projects are created to deploy the sender and receiver projects. The projects are tested by sending a sample HL7 message file and verifying the acknowledgement and converted XML files are produced.
BizTalk Server 2009 ESB Guidance 2.0 By Kevin GockKevinGock
A presentation on BizTalk 2009 ESB (Enterprise Service Bus) Guidance at Auckland Connected Systems User Group by Kevin Gock. Thiago Almeida presented Capabilities of BizTalk Server 2009
The document provides an overview of enterprise service buses (ESBs). It defines an ESB as a software architecture that provides integration services through messaging and standards-based integration. The key capabilities of an ESB are described as routing, transformation, choreography, orchestration, transaction management, and security. The document outlines the typical components of an ESB including a mediator, service registry, choreographer, and rules engine. It discusses how process choreography relates to the mediator and considerations for their relationship. Open source ESB projects like Mule and ServiceMix are also mentioned.
This document provides an introduction to Mule, an open-source enterprise service bus (ESB). It discusses what Mule is, how to use it, and some of its core concepts. Mule uses technologies like staged event-driven architecture (SEDA) and Java NIO to process events and messages asynchronously and efficiently. The document then explains Mule concepts like endpoints, transports, connectors, routers, filters, transformers and the universal message object (UMO) that Mule uses to process events through its pipeline. It provides examples of using Mule with file endpoints and XML pipelines.
Hl7 Standards, Reference Information Model & Clinical Document ArchitectureNawanan Theera-Ampornpunt
This document discusses HL7 standards and includes information about:
- HL7 version 2 (HL7 v2), which is the most commonly used HL7 standard for defining electronic messages supporting hospital operations.
- HL7 version 3, which adds semantic capability to messaging.
- The Clinical Document Architecture (CDA), which defines the structure and semantics of clinical documents.
This document describes how to create simple HL7 sender and receiver projects using OpenESB. It provides step-by-step instructions for creating the BPEL and composite application projects for an HL7 sender that polls a file system for HL7 messages and sends them over MLLP, and an HL7 receiver that receives messages over MLLP and writes them to XML files. The projects demonstrate sending an HL7 message from the sender to the receiver, and receiving an acknowledgement file from the receiver.
The document provides a 5-step plan to deploy a simple "Hello World" website to Bluemix:
1. Create a toolchain in Bluemix for the new app project.
2. Use the Web IDE to code a simple index.html page that displays "Hello, BluemixWorld!".
3. Create a manifest.yml file to define how to deploy the app.
4. Deploy the app which will open the running website in a new browser window.
5. Commit the code changes to the Git repository to track the project.
A $5 Billion Value: Estimating the Total Development Cost of Linux Foundation’s Collaborative Projects
By Jeff Licquia and Amanda McPherson - A Linux Foundation publication
This document estimates the total development cost of Linux Foundation's collaborative open source projects if they had to be rebuilt from scratch. It analyzes over 115 million lines of source code across various projects. Using the Constructive Cost Model (COCOMO), it estimates it would take over 41,000 person-years of work and cost $5 billion to recreate these projects. The largest projects by lines of code are Tizen and Code Aurora Forum. While a simple analysis, it demonstrates the significant value provided by collaborative open source development.
BizTalk Server 2009 ESB Guidance 2.0 By Kevin GockKevinGock
A presentation on BizTalk 2009 ESB (Enterprise Service Bus) Guidance at Auckland Connected Systems User Group by Kevin Gock. Thiago Almeida presented Capabilities of BizTalk Server 2009
The document provides an overview of enterprise service buses (ESBs). It defines an ESB as a software architecture that provides integration services through messaging and standards-based integration. The key capabilities of an ESB are described as routing, transformation, choreography, orchestration, transaction management, and security. The document outlines the typical components of an ESB including a mediator, service registry, choreographer, and rules engine. It discusses how process choreography relates to the mediator and considerations for their relationship. Open source ESB projects like Mule and ServiceMix are also mentioned.
This document provides an introduction to Mule, an open-source enterprise service bus (ESB). It discusses what Mule is, how to use it, and some of its core concepts. Mule uses technologies like staged event-driven architecture (SEDA) and Java NIO to process events and messages asynchronously and efficiently. The document then explains Mule concepts like endpoints, transports, connectors, routers, filters, transformers and the universal message object (UMO) that Mule uses to process events through its pipeline. It provides examples of using Mule with file endpoints and XML pipelines.
Hl7 Standards, Reference Information Model & Clinical Document ArchitectureNawanan Theera-Ampornpunt
This document discusses HL7 standards and includes information about:
- HL7 version 2 (HL7 v2), which is the most commonly used HL7 standard for defining electronic messages supporting hospital operations.
- HL7 version 3, which adds semantic capability to messaging.
- The Clinical Document Architecture (CDA), which defines the structure and semantics of clinical documents.
This document describes how to create simple HL7 sender and receiver projects using OpenESB. It provides step-by-step instructions for creating the BPEL and composite application projects for an HL7 sender that polls a file system for HL7 messages and sends them over MLLP, and an HL7 receiver that receives messages over MLLP and writes them to XML files. The projects demonstrate sending an HL7 message from the sender to the receiver, and receiving an acknowledgement file from the receiver.
The document provides a 5-step plan to deploy a simple "Hello World" website to Bluemix:
1. Create a toolchain in Bluemix for the new app project.
2. Use the Web IDE to code a simple index.html page that displays "Hello, BluemixWorld!".
3. Create a manifest.yml file to define how to deploy the app.
4. Deploy the app which will open the running website in a new browser window.
5. Commit the code changes to the Git repository to track the project.
A $5 Billion Value: Estimating the Total Development Cost of Linux Foundation’s Collaborative Projects
By Jeff Licquia and Amanda McPherson - A Linux Foundation publication
This document estimates the total development cost of Linux Foundation's collaborative open source projects if they had to be rebuilt from scratch. It analyzes over 115 million lines of source code across various projects. Using the Constructive Cost Model (COCOMO), it estimates it would take over 41,000 person-years of work and cost $5 billion to recreate these projects. The largest projects by lines of code are Tizen and Code Aurora Forum. While a simple analysis, it demonstrates the significant value provided by collaborative open source development.
Webcast Presentation: Be lean. Be agile. Work together with DevOps Services (...GRUC
This document provides information about how to connect with the Rational user community through various online channels, including the Rational user group website, Twitter, LinkedIn, and Google+. It lists the URLs for joining discussions or following news on each of these platforms.
Open Source means a lot of things and revolutionized the way software is built over the last two decades.
Whether developing a product or providing a service, companies are rushing to get their businesses cloud ready, increasingly (big) data driven and flexible enough to take advantage of the inherent business scalability opportunities offered by the cloud.
And as the focus switches to the scale economies of execution, from ever cheaper opaque hosted web storage and connected services to the immutable containers movement, a question arises: what is the role of Open Source software in a world in which not only software (SaaS), but also platform (PaaS) and infrastructure (IaaS) are increasingly delivered (and consumed) as hosted services?
In this session, we'll attempt to answer to this question, by providing examples of Open Source cloud & big data companies and studying the effects of open development ecosystems and how Open Source is engrained in the fabric of the Cloud.
This document summarizes the OpenChain Japan Work Group Meeting #27. It welcomed new members and thanked hosts. OpenChain membership represents over $5.9 trillion in market value and its standards help various industries like automotive, banking, and cloud computing. Key updates included progress on ISO/IEC 5230 and DIS 18974 standards, and 98 organizations achieving ISO/IEC 5230 conformance. Work continued on improving OpenChain specifications and activities like webinars. A legal work group was formed to develop model procurement language incorporating OpenChain standards.
Using Clojure, NoSQL Databases and Functional-Style JavaScript to Write Gext-...Stefan Richter
The document is a presentation about building next-generation HTML5 apps using Clojure, NoSQL databases, and functional JavaScript. It discusses how the presenter built an HTML5 client for their software company's app using these technologies that runs on all modern browsers and mobile platforms like iPhone and Android, avoiding the need to build separate native apps. The presentation focuses on their use of functional programming principles in JavaScript to structure the client code.
Self-Contained Systems und Microfrontends in der Praxis.pdfMichael Lehmann
So what starts out as a simple web application can, after 20 years, end up as a huge, sluggish monolith that can hardly be maintained, or even developed further. So there are always customer projects in which we have to replace such old systems. A modern, flexible and future-oriented architecture is often a driving requirement in these cases.
With self-contained systems, we have an architecture that we use to design large web applications and customer portals. This architecture ensures that the system remains manageable and maintainable in individual, independent modules. I would like to give you an overview of the Self-Contained Systems architecture and share our experiences with you.
Jeff Reynolds is the Director of Enterprise Solutions Consulting at CollabNet. He has over 24 years of experience in software development. CollabNet provides an enterprise platform called TeamForge that allows organizations to securely manage development tools like Git and Subversion across distributed teams. TeamForge uses a community architecture approach with features like site organization, access controls, templates, and associating related intellectual property to address the needs of highly complex organizations.
Open Source Compliance at Orange, OW2online, June 2020OW2
Presentation by Nicolas Toussaint, Software Architect, Orange.
Abstract: Orange and Orange Business Services have turned to full open source solutions to tackle the complex problem of respecting the open source legal compliance constraints.
This talk presents the journey undertaken the past few years to build and improve the existing tooling and processes to make compliance validation possible, as well as allow overseeing progresses.
Open Source project failure often stems from not setting clear objectives or having a shared vision from the start. That said there are many success stories, including two well known Statistical examples: Demetra; and Eurostat SDMX tools (SDMX-RI). However, in all these examples there was at first a founding organisation/entity that created the right environment for its successful path into a new paradigm. In the context of my presentation this being the Statistical Information System Collaboration Community (SIS-CC / http://siscc.oecd.org).
Presented at the International Marketing and Output DataBase Conference, Gozd Martuljek, September 18 - 22, 2016.
10 Minutes Bluemix Pitch from Dev to Dev
Video: https://www.youtube.com/watch?v=U7zS1_6TZD8
Niklas Heidloff, IBM, Bluemix Developer Advocate
http://twitter.com/nheidloff,
http://heidloff.net
https://bluemix.net
This document summarizes an IBM Bluemix meetup that took place on May 4, 2016 in Triangle, North Carolina. The meetup included presentations on Swift, OpenWhisk, Blockchain/Hyperledger, and a Q&A session. Attendees could learn about new technologies on IBM Bluemix like the Swift sandbox, OpenWhisk serverless platform, and IBM's involvement in the Hyperledger blockchain project. The next Bluemix meetup was scheduled for May 18, 2016.
This document provides instructions for using IBM Bluemix and IBM Bluemix DevOps Services (IDS) to build and deploy a Docker container application. It demonstrates setting up a continuous delivery pipeline that will automatically build and deploy new versions of an application. Users are instructed to fork a sample project code from IDS, inspect the code, configure build and deploy stages in the pipeline, and then run builds to deploy new versions after making code changes. The pipeline is triggered by committing code changes to the Git repository.
Help students get familiar with the basic concepts of DevOps processes and technologies and the challenges facing companies who are looking to embrace scalable software deployment.
[This workshop was given to TAU CS students over the years 2015-2016]
Getting started-with-oracle-so a lab#12Amit Sharma
This document provides steps to create an Oracle SOA composite application that demonstrates parallel processing using a flow activity. The application takes two input numbers, and within the flow activity it concurrently calculates the addition, subtraction, multiplication, and division of the numbers. It outputs all the results. The flow trace is examined to confirm the activities within the flow executed simultaneously in parallel.
"Open Source as a enabler for industry collaborations and innovation!" by Gaë...Mindtrek
Track | the Future of Open Source Business
Gaël Blondelle, Chief Membership Officer, Eclipse Foundation
Mindtrek Conference
15th of November 2022.
Tampere, Finland
www.mindtrek.org
Complex Made Simple @ Bird&Birds OpenChain SeminarShane Coughlan
This document discusses the OpenChain Project which aims to create a simple, effective industry standard for open source license compliance for organizations of all sizes. It establishes trust in multi-entity compliance through shared rules and results. The project defines best practices for compliance processes like policy, training, and tooling. It also outlines the project's status including meetings held in various regions to promote OpenChain and working groups on automotive and reference tooling. The goal is to raise awareness and simplify open source compliance.
The summary of the OpenChain Monthly Meeting document is:
1. The meeting covered announcements regarding increased support for the OpenChain Security Assurance Specification from certification organizations globally, as well as the first organization achieving conformance with the spec.
2. Updates were provided on SPDX Python tools and an upcoming OSPOlogy event.
3. The OpenChain Automation work group discussed publishing the Capability Map in different formats and a new open source compliance database project.
4. Discussions were held on potential improvements to the License Compliance and Security Assurance specifications.
5. The Education work group outlined priorities like a document on focus areas and continuing work on revamping the website.
In this presentation we'll explore the latest developments in MuleSoft's Anypoint Code Builder IDE and how it can help streamline your integration projects. We'll also dive into the exciting world of Splunk and demonstrate how to efficiently push your application logs to Splunk for real-time analysis and troubleshooting.
This document provides instructions for deploying the ContentBox modular CMS to the Jelastic cloud platform. It outlines the steps to create a Jelastic account, deploy ContentBox via SSH, extract the ContentBox zip file, and complete the installer process in a browser. The document also provides contact information for George Murphy, a ColdFusion engineer, in case the user has any other questions.
The document provides step-by-step instructions for creating a simple "Hello World" project in Oracle SOA. It describes creating an XSD file, BPEL process, and assign activity. The project is then deployed and tested using the Enterprise Manager console. Key steps include generating a WSDL, viewing message enveloping with SOAP, and launching a flow trace to see the process instance.
Travel Clinic Cardiff: Health Advice for International TravelersNX Healthcare
Travel Clinic Cardiff offers comprehensive travel health services, including vaccinations, travel advice, and preventive care for international travelers. Our expert team ensures you are well-prepared and protected for your journey, providing personalized consultations tailored to your destination. Conveniently located in Cardiff, we help you travel with confidence and peace of mind. Visit us: www.nxhealthcare.co.uk
Webcast Presentation: Be lean. Be agile. Work together with DevOps Services (...GRUC
This document provides information about how to connect with the Rational user community through various online channels, including the Rational user group website, Twitter, LinkedIn, and Google+. It lists the URLs for joining discussions or following news on each of these platforms.
Open Source means a lot of things and revolutionized the way software is built over the last two decades.
Whether developing a product or providing a service, companies are rushing to get their businesses cloud ready, increasingly (big) data driven and flexible enough to take advantage of the inherent business scalability opportunities offered by the cloud.
And as the focus switches to the scale economies of execution, from ever cheaper opaque hosted web storage and connected services to the immutable containers movement, a question arises: what is the role of Open Source software in a world in which not only software (SaaS), but also platform (PaaS) and infrastructure (IaaS) are increasingly delivered (and consumed) as hosted services?
In this session, we'll attempt to answer to this question, by providing examples of Open Source cloud & big data companies and studying the effects of open development ecosystems and how Open Source is engrained in the fabric of the Cloud.
This document summarizes the OpenChain Japan Work Group Meeting #27. It welcomed new members and thanked hosts. OpenChain membership represents over $5.9 trillion in market value and its standards help various industries like automotive, banking, and cloud computing. Key updates included progress on ISO/IEC 5230 and DIS 18974 standards, and 98 organizations achieving ISO/IEC 5230 conformance. Work continued on improving OpenChain specifications and activities like webinars. A legal work group was formed to develop model procurement language incorporating OpenChain standards.
Using Clojure, NoSQL Databases and Functional-Style JavaScript to Write Gext-...Stefan Richter
The document is a presentation about building next-generation HTML5 apps using Clojure, NoSQL databases, and functional JavaScript. It discusses how the presenter built an HTML5 client for their software company's app using these technologies that runs on all modern browsers and mobile platforms like iPhone and Android, avoiding the need to build separate native apps. The presentation focuses on their use of functional programming principles in JavaScript to structure the client code.
Self-Contained Systems und Microfrontends in der Praxis.pdfMichael Lehmann
So what starts out as a simple web application can, after 20 years, end up as a huge, sluggish monolith that can hardly be maintained, or even developed further. So there are always customer projects in which we have to replace such old systems. A modern, flexible and future-oriented architecture is often a driving requirement in these cases.
With self-contained systems, we have an architecture that we use to design large web applications and customer portals. This architecture ensures that the system remains manageable and maintainable in individual, independent modules. I would like to give you an overview of the Self-Contained Systems architecture and share our experiences with you.
Jeff Reynolds is the Director of Enterprise Solutions Consulting at CollabNet. He has over 24 years of experience in software development. CollabNet provides an enterprise platform called TeamForge that allows organizations to securely manage development tools like Git and Subversion across distributed teams. TeamForge uses a community architecture approach with features like site organization, access controls, templates, and associating related intellectual property to address the needs of highly complex organizations.
Open Source Compliance at Orange, OW2online, June 2020OW2
Presentation by Nicolas Toussaint, Software Architect, Orange.
Abstract: Orange and Orange Business Services have turned to full open source solutions to tackle the complex problem of respecting the open source legal compliance constraints.
This talk presents the journey undertaken the past few years to build and improve the existing tooling and processes to make compliance validation possible, as well as allow overseeing progresses.
Open Source project failure often stems from not setting clear objectives or having a shared vision from the start. That said there are many success stories, including two well known Statistical examples: Demetra; and Eurostat SDMX tools (SDMX-RI). However, in all these examples there was at first a founding organisation/entity that created the right environment for its successful path into a new paradigm. In the context of my presentation this being the Statistical Information System Collaboration Community (SIS-CC / http://siscc.oecd.org).
Presented at the International Marketing and Output DataBase Conference, Gozd Martuljek, September 18 - 22, 2016.
10 Minutes Bluemix Pitch from Dev to Dev
Video: https://www.youtube.com/watch?v=U7zS1_6TZD8
Niklas Heidloff, IBM, Bluemix Developer Advocate
http://twitter.com/nheidloff,
http://heidloff.net
https://bluemix.net
This document summarizes an IBM Bluemix meetup that took place on May 4, 2016 in Triangle, North Carolina. The meetup included presentations on Swift, OpenWhisk, Blockchain/Hyperledger, and a Q&A session. Attendees could learn about new technologies on IBM Bluemix like the Swift sandbox, OpenWhisk serverless platform, and IBM's involvement in the Hyperledger blockchain project. The next Bluemix meetup was scheduled for May 18, 2016.
This document provides instructions for using IBM Bluemix and IBM Bluemix DevOps Services (IDS) to build and deploy a Docker container application. It demonstrates setting up a continuous delivery pipeline that will automatically build and deploy new versions of an application. Users are instructed to fork a sample project code from IDS, inspect the code, configure build and deploy stages in the pipeline, and then run builds to deploy new versions after making code changes. The pipeline is triggered by committing code changes to the Git repository.
Help students get familiar with the basic concepts of DevOps processes and technologies and the challenges facing companies who are looking to embrace scalable software deployment.
[This workshop was given to TAU CS students over the years 2015-2016]
Getting started-with-oracle-so a lab#12Amit Sharma
This document provides steps to create an Oracle SOA composite application that demonstrates parallel processing using a flow activity. The application takes two input numbers, and within the flow activity it concurrently calculates the addition, subtraction, multiplication, and division of the numbers. It outputs all the results. The flow trace is examined to confirm the activities within the flow executed simultaneously in parallel.
"Open Source as a enabler for industry collaborations and innovation!" by Gaë...Mindtrek
Track | the Future of Open Source Business
Gaël Blondelle, Chief Membership Officer, Eclipse Foundation
Mindtrek Conference
15th of November 2022.
Tampere, Finland
www.mindtrek.org
Complex Made Simple @ Bird&Birds OpenChain SeminarShane Coughlan
This document discusses the OpenChain Project which aims to create a simple, effective industry standard for open source license compliance for organizations of all sizes. It establishes trust in multi-entity compliance through shared rules and results. The project defines best practices for compliance processes like policy, training, and tooling. It also outlines the project's status including meetings held in various regions to promote OpenChain and working groups on automotive and reference tooling. The goal is to raise awareness and simplify open source compliance.
The summary of the OpenChain Monthly Meeting document is:
1. The meeting covered announcements regarding increased support for the OpenChain Security Assurance Specification from certification organizations globally, as well as the first organization achieving conformance with the spec.
2. Updates were provided on SPDX Python tools and an upcoming OSPOlogy event.
3. The OpenChain Automation work group discussed publishing the Capability Map in different formats and a new open source compliance database project.
4. Discussions were held on potential improvements to the License Compliance and Security Assurance specifications.
5. The Education work group outlined priorities like a document on focus areas and continuing work on revamping the website.
In this presentation we'll explore the latest developments in MuleSoft's Anypoint Code Builder IDE and how it can help streamline your integration projects. We'll also dive into the exciting world of Splunk and demonstrate how to efficiently push your application logs to Splunk for real-time analysis and troubleshooting.
This document provides instructions for deploying the ContentBox modular CMS to the Jelastic cloud platform. It outlines the steps to create a Jelastic account, deploy ContentBox via SSH, extract the ContentBox zip file, and complete the installer process in a browser. The document also provides contact information for George Murphy, a ColdFusion engineer, in case the user has any other questions.
The document provides step-by-step instructions for creating a simple "Hello World" project in Oracle SOA. It describes creating an XSD file, BPEL process, and assign activity. The project is then deployed and tested using the Enterprise Manager console. Key steps include generating a WSDL, viewing message enveloping with SOAP, and launching a flow trace to see the process instance.
Travel Clinic Cardiff: Health Advice for International TravelersNX Healthcare
Travel Clinic Cardiff offers comprehensive travel health services, including vaccinations, travel advice, and preventive care for international travelers. Our expert team ensures you are well-prepared and protected for your journey, providing personalized consultations tailored to your destination. Conveniently located in Cardiff, we help you travel with confidence and peace of mind. Visit us: www.nxhealthcare.co.uk
DECLARATION OF HELSINKI - History and principlesanaghabharat01
This SlideShare presentation provides a comprehensive overview of the Declaration of Helsinki, a foundational document outlining ethical guidelines for conducting medical research involving human subjects.
Osteoporosis - Definition , Evaluation and Management .pdfJim Jacob Roy
Osteoporosis is an increasing cause of morbidity among the elderly.
In this document , a brief outline of osteoporosis is given , including the risk factors of osteoporosis fractures , the indications for testing bone mineral density and the management of osteoporosis
- Video recording of this lecture in English language: https://youtu.be/Pt1nA32sdHQ
- Video recording of this lecture in Arabic language: https://youtu.be/uFdc9F0rlP0
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
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10 Benefits an EPCR Software should Bring to EMS Organizations Traumasoft LLC
The benefits of an ePCR solution should extend to the whole EMS organization, not just certain groups of people or certain departments. It should provide more than just a form for entering and a database for storing information. It should also include a workflow of how information is communicated, used and stored across the entire organization.
8 Surprising Reasons To Meditate 40 Minutes A Day That Can Change Your Life.pptxHolistified Wellness
We’re talking about Vedic Meditation, a form of meditation that has been around for at least 5,000 years. Back then, the people who lived in the Indus Valley, now known as India and Pakistan, practised meditation as a fundamental part of daily life. This knowledge that has given us yoga and Ayurveda, was known as Veda, hence the name Vedic. And though there are some written records, the practice has been passed down verbally from generation to generation.
Does Over-Masturbation Contribute to Chronic Prostatitis.pptxwalterHu5
In some case, your chronic prostatitis may be related to over-masturbation. Generally, natural medicine Diuretic and Anti-inflammatory Pill can help mee get a cure.
5-hydroxytryptamine or 5-HT or Serotonin is a neurotransmitter that serves a range of roles in the human body. It is sometimes referred to as the happy chemical since it promotes overall well-being and happiness.
It is mostly found in the brain, intestines, and blood platelets.
5-HT is utilised to transport messages between nerve cells, is known to be involved in smooth muscle contraction, and adds to overall well-being and pleasure, among other benefits. 5-HT regulates the body's sleep-wake cycles and internal clock by acting as a precursor to melatonin.
It is hypothesised to regulate hunger, emotions, motor, cognitive, and autonomic processes.
Mercurius is named after the roman god mercurius, the god of trade and science. The planet mercurius is named after the same god. Mercurius is sometimes called hydrargyrum, means ‘watery silver’. Its shine and colour are very similar to silver, but mercury is a fluid at room temperatures. The name quick silver is a translation of hydrargyrum, where the word quick describes its tendency to scatter away in all directions.
The droplets have a tendency to conglomerate to one big mass, but on being shaken they fall apart into countless little droplets again. It is used to ignite explosives, like mercury fulminate, the explosive character is one of its general themes.
Cell Therapy Expansion and Challenges in Autoimmune DiseaseHealth Advances
There is increasing confidence that cell therapies will soon play a role in the treatment of autoimmune disorders, but the extent of this impact remains to be seen. Early readouts on autologous CAR-Ts in lupus are encouraging, but manufacturing and cost limitations are likely to restrict access to highly refractory patients. Allogeneic CAR-Ts have the potential to broaden access to earlier lines of treatment due to their inherent cost benefits, however they will need to demonstrate comparable or improved efficacy to established modalities.
In addition to infrastructure and capacity constraints, CAR-Ts face a very different risk-benefit dynamic in autoimmune compared to oncology, highlighting the need for tolerable therapies with low adverse event risk. CAR-NK and Treg-based therapies are also being developed in certain autoimmune disorders and may demonstrate favorable safety profiles. Several novel non-cell therapies such as bispecific antibodies, nanobodies, and RNAi drugs, may also offer future alternative competitive solutions with variable value propositions.
Widespread adoption of cell therapies will not only require strong efficacy and safety data, but also adapted pricing and access strategies. At oncology-based price points, CAR-Ts are unlikely to achieve broad market access in autoimmune disorders, with eligible patient populations that are potentially orders of magnitude greater than the number of currently addressable cancer patients. Developers have made strides towards reducing cell therapy COGS while improving manufacturing efficiency, but payors will inevitably restrict access until more sustainable pricing is achieved.
Despite these headwinds, industry leaders and investors remain confident that cell therapies are poised to address significant unmet need in patients suffering from autoimmune disorders. However, the extent of this impact on the treatment landscape remains to be seen, as the industry rapidly approaches an inflection point.
2. Page | 1
Visit LogiCoy.com
ABOUT LOGICOY
LogiCoy incorporated in February 2009.
Headquarters in Los Angeles, California with 24/7 offices in US, and
India, is a Global Information Technology and Services company
providing products and services in integration and middleware across
various industries including financial, healthcare, telecommunications,
manufacturing, and government.
We are the original architects, developers and engineering managers
and directors for Seebeyond eGate, ICAN, Sun Java CAPS, Mural
MDM,Open/GlassFish ESB products from inception to end and know
the code inside and out.
We are active committers of the OpenESB codebase in the OpenESB
Open source repository and actively working on the enhancements
and new versions of OpenESB.
We have augmented our product development with very seasoned
SOA/EAI Technical Leads and Architects for integration solutions with
field implementation experience using Sun Java CAPS, GlassFish
ESB, eGate and other integration tools in healthcare integration
projects.
Contact us at: info@logicoy.com
ABOUT THE AUTHOR
Fred Aabedi is the Chief Technology Officer at LogiCoy. Prior to LogiCoy,
he was the Senior Engineering Director for the Sun Java CAPS, GlassFish
ESB components, and SeeBeyond ICAN, and eGate 4.5 Suite of adapters,
addons, and messaging libraries. He also held Chief Technical Advisor role
for healthcare and financial and government sectors in the Sun SOA
Business Integration Engineering group. He was the OpenESB Community
lead from inception to near the end of Sun acquisition by Oracle and
currently very active in many aspects of the OpenESB community.
3. Page | 2
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Table of Contents
Introduction...........................................................................................................................................................................2
Create HL7 Sender BPEL Project.....................................................................................................................................4
Create WSDLs for the HL7 Sender Project...................................................................................................................5
Create HL7 Sender Composite Application Project ................................................................................................. 14
Deploy HL7 Sender Composite Application Project................................................................................................. 17
Create HL7 Receiver BPEL Project................................................................................................................................ 18
Create WSDLs for the HL7 Receiver Project.............................................................................................................. 19
Create HL7 Receiver Composite Application Project............................................................................................... 25
Deploy HL7 Receiver Composite Application Project .............................................................................................. 27
Test HL7 Sender and Receiver Projects....................................................................................................................... 28
Conclusion.......................................................................................................................................................................... 30
Introduction
This document describes how to create a simple HL7 Sender and Receiver
project.
I am assuming you have done some basic OpenESB projects. If you have
not, you may want to try a HelloWorld example in OpenESB first to get
familiar with OpenESB.
The HL7 Sender project polls for files on a file system containing HL7
messages and sends them over MLLP to an HL7 external using the HL7
Outbound port and then writes the acknowledgement back to the file
system.
The HL7 Consumer (Receiver) project connects up the HL7 interface over
MLLP (port 4040) and receives the HL7 messages, converts to XML and
writes the data out to a file in XML format.
To create or use these projects you need an OpenESB installation.
There are other articles for installing OpenESB. I recommend installing
OpenESB V2.3 from the community site:
http://open-esb.net/index.php?option=com_content&view=article&id=113&Itemid=583
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Once installed and running, please use the GlassFish admin console to
install the HL7 Binding Component runtime jar from:
https://s3.amazonaws.com/LogiCoy/OpenESB2.3/hl7bc-installer-2.3.0-SNAPSHOT.jar
Choose directory where the HL7 BC jar is, click Open Next Finish
If you would like to import and use the projects instead of creating them
from scratch, please download the zip file from the link below and unzip to
your netbeans project folder:
https://s3.amazonaws.com/LogiCoy/OpenESB2.3/Examples/HL7Projects.zip
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Create HL7 Sender BPEL Project
First, we create the HL7 Sender BPEL project!
Run the OpenESB Netbeans IDE.
Select Projects tab and New Project SOABPEL Module- Enter project
name HL7MsgSender and click Finish
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Create WSDLs for the HL7 Sender Project
For this HL7 Sender project we need a File and a HL7 WSDL.
HL7MsgSender_FileReceive WSDL:
Input1
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Output1
For the File Inbound, file-address, you can specify a File Binding
Component Application Variable instead of hard coding the directory path.
This is a good practice and allows for defining the value to be determined
based on your environment settings on the GlassFish admin server. The
variable name is: ${hl7MsgPollDir}.
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Please set an appropriate value for it on the GlassFish admin console.
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HL7MsgSender_HL7Send WSDL:
This is the outbound HL7BC WSDL and you need to set appropriate
host/port values, for hl7:address
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Now you can edit your HL7MsgSender BPEL process and drag and drop
the FileReceive WSDL to the left side of the BPEL editor and HL7Sender
WSDL to the right.
You can then add partner links!
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Create HL7 Receiver BPEL Project
FileNew Project SOABPEL Module- Enter project name
HL7MsgConsumer and click Finish
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Create WSDLs for the HL7 Receiver Project
For this HL7 Receiver project we need a File and a HL7 WSDL.
HL7MsgConsumer_FileSend WSDL:
FileOutboundBinding - Input1
Output filename: HL7Msg.xml
For the File Outbound, file-address, you can specify a File Binding
Component Application Variable instead of hard coding the directory path.
This is a good practice and allows for defining the value to be determined
based on your environment settings on the GlassFish admin server. The
variable name is: ${hl7MsgOutDir}.
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Please set an appropriate value for it on the GlassFish admin console.
HL7MsgConsumer_HL7Receiver WSDL:
This is the inbound HL7BC WSDL and you need to set appropriate
host/port values, for hl7:address
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and hl7:protocolproperties
Now you can edit your HL7MsgConsumer BPEL process and drag and
drop the HL7MsgReceive WSDL to the left side of the BPEL editor and
FileSend WSDL to the right.
You can then add partner links!
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Test HL7 Sender and Receiver Projects
Create a file with name HL7Msg.hl7 and place it in the inbound file
directory indicated by your FIleBC application variable
${hl7MsgPollDir}, which in this case is tmpdata and put some HL7
data in it. For example:
MSH|^~&|SMS|IAH|CERNER|PATHNT|200201291848||ADT^A03|agre|P|2
.3|||AL|NE|
EVN|A01|200201291848|||ABCKB1
PID||53820452|00664524|220675537|SMITH^JOHN^^^^||19781218|M||E|1
234 MAIN RD #B1^^LOS ANGELES^CA^90024||(310)555-
5555|||||0012320412|220675537||
PV1||I|2324^2302^-B ||||04100^SMITH EDWARD
M|||MED|||||||04100^SMITH EDWARD
M|S||S|P||||||||||||||||||IAH|||||200201291848|
PV2|||^SEIZURE, FEVER, RLQ PAIN
Observe, that the file is picked up by the HL7 Sender project , and sent to
the HL7 Receiver project via MLLP protocol and that an acknowledgement
is received and written back to the file system with filename HL7Ack.txt with
the following content:
MSH|^~&|CERNER|PATHNT|SMS|IAH|200201291848||ACK|agre|P|2.3
MSA|AA|agre
Also, observe that the HL7 Consumer (Receiver) project receives the HL7
message from the HL7 Sender project over MLLP (port 4040) and converts
it to XML and writes the data out to the HL7Msg.xml file in the directory
pointed to by by your FIleBC application variable ${hl7MsgOutDir}.
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The contents look should like this:
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Conclusion
I hope this tutorial is helpful in your usage of OpenESB for HL7 integration
projects.
Please note that you can substitute your own HL7 Sender or Receiver
external system using any other HL7 compliant tool to communicate and
exchange data with the appropriate OpenESB HL7 project counterpart.
You can access additional tutorials on the LogiCoy blog page:
http://logicoy.com/logicoyblog/
Also, the OpenESB Community Website contains additional tutorials:
http://www.open-esb.net/
Also, Michael Czapski has healthcare related tutorials:
http://blogs.czapski.id.au/wp-
content/uploads/2013/03/OpenESBIsALiveAndWellAndLivingIn..._v0.1.0.pdf
http://blogs.czapski.id.au/category/openesb-v2-3-articles
Please send your comments/feedback about this article to:
info@logicoy.com