Roger Kitterman, Managing Partner of Innovation Fund, Partners Healthcare, presents at MEDTECH 2013 on October 8, 2013 on Trends in Early Stage Medical Technologies: A Venture Perspective.
IP Due Diligence - What Investors Want to See | Matthew Grumbling | Lunch & L...UCICove
About UCI Applied Innovation:
UCI Applied Innovation is a dynamic, innovative central platform for the UCI campus, entrepreneurs, inventors, the business community and investors to collaborate and move UCI research from lab to market.
About the Cove @ UCI:
To accelerate collaboration by better connecting innovation partners in Orange County, UCI Applied Innovation created the Cove, a physical, state-of-the-art hub for entrepreneurs to gather and navigate the resources available both on and off campus. The Cove is headquarters for UCI Applied Innovation, as well as houses several ecosystem partners including incubators, accelerators, angel investors, venture capitalists, mentors and legal experts.
Follow us on social media:
Facebook: @UCICove
Twitter: @UCICove
Instagram: @UCICove
LinkedIn: @UCIAppliedInnovation
For more information:
cove@uci.edu
http://innovation.uci.edu/s.
IP Due Diligence - What Investors Want to See | Matthew Grumbling | Lunch & L...UCICove
About UCI Applied Innovation:
UCI Applied Innovation is a dynamic, innovative central platform for the UCI campus, entrepreneurs, inventors, the business community and investors to collaborate and move UCI research from lab to market.
About the Cove @ UCI:
To accelerate collaboration by better connecting innovation partners in Orange County, UCI Applied Innovation created the Cove, a physical, state-of-the-art hub for entrepreneurs to gather and navigate the resources available both on and off campus. The Cove is headquarters for UCI Applied Innovation, as well as houses several ecosystem partners including incubators, accelerators, angel investors, venture capitalists, mentors and legal experts.
Follow us on social media:
Facebook: @UCICove
Twitter: @UCICove
Instagram: @UCICove
LinkedIn: @UCIAppliedInnovation
For more information:
cove@uci.edu
http://innovation.uci.edu/s.
The old model of selling purely on clinical benefit in the U.S. healthcare industry is dead. Profound changes are underway in how hospitals and other healthcare providers make purchase decisions for medical devices, services, diagnostics, and pharmaceuticals.
In this half-hour webinar, Christopher Provines describes the dramatic impact that the Accountable Care Act (ACA) will have on all healthcare suppliers. Chris explains how new purchasing practices and business models such as value-based purchasing, bundled payments, Accountable Care Organizations and quality-based reimbursement will change the rules of the game for selling and negotiating.
Learn:
* Tips for how to effectively engage customers in this "new normal" healthcare environment
* Strategies for quantifying the value of your offering and how to connect it to your healthcare customers' business model
* Best practices for how to grow your healthcare business
Main Legal Risk Issues Facing Entrepreneurs | Virginia Suveiu | Lunch & Learn UCICove
About UCI Applied Innovation:
UCI Applied Innovation is a dynamic, innovative central platform for the UCI campus, entrepreneurs, inventors, the business community and investors to collaborate and move UCI research from lab to market.
About the Cove @ UCI:
To accelerate collaboration by better connecting innovation partners in Orange County, UCI Applied Innovation created the Cove, a physical, state-of-the-art hub for entrepreneurs to gather and navigate the resources available both on and off campus. The Cove is headquarters for UCI Applied Innovation, as well as houses several ecosystem partners including incubators, accelerators, angel investors, venture capitalists, mentors and legal experts.
Follow us on social media:
Facebook: @UCICove
Twitter: @UCICove
Instagram: @UCICove
LinkedIn: @UCIAppliedInnovation
For more information:
cove@uci.edu
http://innovation.uci.edu/
Bid to Win workshop for Seedbed - October 2015Matt Spry
If your business is supplying services or products to other organisations, and you want to grow, it is almost certain that you will have to navigate the minefield of tendering for new work. When done well successful bidding can help to scale your financial performance and impact quickly, but done badly and you risk wasting huge amounts of time and money.
The Bid to Win masterclass will give you:
- an introduction to bidding
- key principles for bidding to win
- an approach to bidding that can be applied to any sector or opportunity - the bid canvas
The aim of the session was to introduce attendees to a flexible and powerful approach to bidding that will keep your bids focused on what really matters to the buyer, whilst helping to manage the risks inherent in the tendering process.
Presentation at Harvard Medical School and CIMIT (Center for Integration of Medicine & Innovative Technology) on Techniques for Inventing, Funding, Developing & Commercializing High Impact Clinical Innovations
Idea buyer - identifying startup ideas for businessIdea Buyer
Idea buyer now providing identifying startup ideas for new business to grow easily in the present market. Now the real time market is difficult to make a place so we need running plans to achieve business goal.
MEDTECH 2013 Closing Plenary, Andy Shaudt, Director of Usability Services, Na...MedTechAssociation
MEDTECH 2013 Closing Plenary, Andy Shaudt, Director of Usability Services, National Center for Human Factors in Healthcare, MedStar Institute for Innovation, presents on Design and Development of Medical Devices through a Human Factors and Usability Lens on October 8, 2013
The old model of selling purely on clinical benefit in the U.S. healthcare industry is dead. Profound changes are underway in how hospitals and other healthcare providers make purchase decisions for medical devices, services, diagnostics, and pharmaceuticals.
In this half-hour webinar, Christopher Provines describes the dramatic impact that the Accountable Care Act (ACA) will have on all healthcare suppliers. Chris explains how new purchasing practices and business models such as value-based purchasing, bundled payments, Accountable Care Organizations and quality-based reimbursement will change the rules of the game for selling and negotiating.
Learn:
* Tips for how to effectively engage customers in this "new normal" healthcare environment
* Strategies for quantifying the value of your offering and how to connect it to your healthcare customers' business model
* Best practices for how to grow your healthcare business
Main Legal Risk Issues Facing Entrepreneurs | Virginia Suveiu | Lunch & Learn UCICove
About UCI Applied Innovation:
UCI Applied Innovation is a dynamic, innovative central platform for the UCI campus, entrepreneurs, inventors, the business community and investors to collaborate and move UCI research from lab to market.
About the Cove @ UCI:
To accelerate collaboration by better connecting innovation partners in Orange County, UCI Applied Innovation created the Cove, a physical, state-of-the-art hub for entrepreneurs to gather and navigate the resources available both on and off campus. The Cove is headquarters for UCI Applied Innovation, as well as houses several ecosystem partners including incubators, accelerators, angel investors, venture capitalists, mentors and legal experts.
Follow us on social media:
Facebook: @UCICove
Twitter: @UCICove
Instagram: @UCICove
LinkedIn: @UCIAppliedInnovation
For more information:
cove@uci.edu
http://innovation.uci.edu/
Bid to Win workshop for Seedbed - October 2015Matt Spry
If your business is supplying services or products to other organisations, and you want to grow, it is almost certain that you will have to navigate the minefield of tendering for new work. When done well successful bidding can help to scale your financial performance and impact quickly, but done badly and you risk wasting huge amounts of time and money.
The Bid to Win masterclass will give you:
- an introduction to bidding
- key principles for bidding to win
- an approach to bidding that can be applied to any sector or opportunity - the bid canvas
The aim of the session was to introduce attendees to a flexible and powerful approach to bidding that will keep your bids focused on what really matters to the buyer, whilst helping to manage the risks inherent in the tendering process.
Presentation at Harvard Medical School and CIMIT (Center for Integration of Medicine & Innovative Technology) on Techniques for Inventing, Funding, Developing & Commercializing High Impact Clinical Innovations
Idea buyer - identifying startup ideas for businessIdea Buyer
Idea buyer now providing identifying startup ideas for new business to grow easily in the present market. Now the real time market is difficult to make a place so we need running plans to achieve business goal.
MEDTECH 2013 Closing Plenary, Andy Shaudt, Director of Usability Services, Na...MedTechAssociation
MEDTECH 2013 Closing Plenary, Andy Shaudt, Director of Usability Services, National Center for Human Factors in Healthcare, MedStar Institute for Innovation, presents on Design and Development of Medical Devices through a Human Factors and Usability Lens on October 8, 2013
Design for reimbursement in medical device developmentAmber Hol Horeman
In medical device development it is essential to start with reimbursement strategy from day one to enhance the chance to successful implementation in the healthcare system. This presentation shows the outcomes of a 5 month graduation project to the role of reimbursement in medical device development. The design for reimbursement framework proposed provides an overview for starting entrepreneurs in the complex field of medical devices.
Enabling the Future of Healthcare Through Integration and Interoperability: V...Rahul Neel Mani
Integration is about connecting two or more systems so that they can share data. Interoperability means that two (or more) systems work together unchanged even though they weren't necessarily designed to work together.
Trends in Global Medical Device OEM Strategies and Issues for the Medical Dev...Tony Freeman
Presented at the February, 2013 mdmX Conference, Manning Advisors' Tony Freeman reviews issues facing the largest medical device manufacturers and implications for their supply chain.
Healthcare Interoperability: New Tactics and TechnologyHealth Catalyst
Every provider agrees on the need for healthcare interoperability to achieve clinical data insights at the point of care. The question is how to get there from the myriad technologies and the volumes of data that comprise electronic medical records. It’s been difficult to organize among participants that have had little incentive to cooperate. And standards for sending and receiving data have been slow to develop. This is changing, but the key components that are still vital to realizing insights are closed-loop analytics and its accompanying tools, an enterprise data warehouse and analytics applications. This article defines the problems and explores the solutions to optimizing clinical decision making where it’s needed most.
An overview of our Technology Accelerator business model. We describe a hybrid model leveraging minimally-dilutive funding and experienced pharmaceutical management to “de-risk” and drive projects to IND. Our area of expertise is prodrugs and infectious diseases (www.tsrlinc.com).
A presentation at the Global Genes rare drug development symposium on governm...Sean Ekins
This presentation from June 12 2020 gives a brief overview of my experience of 15 years of applying for government grants to fund small companies. Prior to this I had no experience of applying for such grants. The bottom line for rare disease groups / families is find a scientist that can do this or assist you. please also see www.collaborationspharma.com
Training for a career in science begins with formal theoretical and practical instruction at an academic institution, often followed by advanced training and eventual employment also at an academic institution. This career path is one which has been historically taken by most scientists.
In recent years, increasing numbers of academic scientists are choosing commercial laboratories to pursue their research careers. This shift in career path is driven to a large degree by the eroding of financial support for academic scientists, as evidenced by the downward trend in the funding rate for grants submitted to the NIH, NSF, and private foundations. Perhaps the greatest challenge for an academic scientist contemplating a move to a commercial laboratory is to adjust their thinking of ‘doing science for science sake’ to ‘doing science for commercializing a product’.
This insightful Webinar will cover areas to be considered when making this career change, including the culture of the commercial laboratory working environment, career advancement, scientific recognition, mentoring, and availability of opportunities.
5 Key Take-Aways:
Similarities and difference between academic and commercial laboratory working environments
Suggestions on how to increase your autonomy and independence in conducting research at a commercial laboratory
How to ‘hedge your bets’ so that deadlines and milestones are reached
Balancing publishing and intellectual property generation
The difference in costs between academic and commercial laboratory research
Who Should Attend:
Any academic PI, scientist, post-doc, graduate student, technician contemplating a move from a university-based research laboratory to a commercial biotechnology or pharmaceutical development laboratory.
Best Practices and Points to Consider for Small-Medium Bio-Pharma CompaniesCovance
Small to medium sized companies face a host of unique challenges in the management of drug safety as they prepare to launch and sustain their products. Lack of clinical, safety and regulatory resources and expertise, along with inadequate technology infrastructure can create significant challenges and risks when advancing products through the life cycle. Find out how you can help your organizations overcome some common obstacles, learn from best practices and efficiently comply with global pharmacovigilance requirements.
The Pediatric Device Center is dedicated to the advancement of pediatric innovation within the healthcare and device industry. Our collaborative approach allows us to provide expertise, cost-effective services, and a wide variety of resources with the help of volunteers and members from around the world. We also partner with healthcare providers, FDA, non-profit organizations, institutions, consortiums, and other industry experts in order to help bring pediatric innovation to life.
Overcoming the Struggles of Small PracticesBen Quirk
Small practices face many struggles on the road to success. This webinar overviews the top obstacles they face, addresses the reasons behind the decline in numbers of independent practices, and provides solutions for them to remain successful despite the challenges.
Chris Cleary, Vice President of Corporate Development, Medtronic presented at MEDTECH 2014 on Fulfilling the Mission: Medtronic Embraces Change to Respond to an Evolving Healthcare Landscape.
John Babitt, Partner, Life Sciences, Transaction Advisory Services, Ernst & Young LLP, presented at MEDTECH 2014 on The State of Change: A Look at the Evolving Healthcare Landscape and the Effect on Life Science Organizations Today and Tomorrow.
MEDTECH 2013 Opening Plenary: Excessive Regulation and the ACA's Medical Devi...MedTechAssociation
John Eckberg, Director of Media Relations at Cook Group opens the MEDTECH 2013 conference on Monday, October 7, 2013 with a presentation on Excessive Regulation and the ACA's Medical Device Tax Harms Patients, Jobs and Innovation.
how to sell pi coins on Bitmart crypto exchangeDOT TECH
Yes. Pi network coins can be exchanged but not on bitmart exchange. Because pi network is still in the enclosed mainnet. The only way pioneers are able to trade pi coins is by reselling the pi coins to pi verified merchants.
A verified merchant is someone who buys pi network coins and resell it to exchanges looking forward to hold till mainnet launch.
I will leave the telegram contact of my personal pi merchant to trade with.
@Pi_vendor_247
The European Unemployment Puzzle: implications from population agingGRAPE
We study the link between the evolving age structure of the working population and unemployment. We build a large new Keynesian OLG model with a realistic age structure, labor market frictions, sticky prices, and aggregate shocks. Once calibrated to the European economy, we quantify the extent to which demographic changes over the last three decades have contributed to the decline of the unemployment rate. Our findings yield important implications for the future evolution of unemployment given the anticipated further aging of the working population in Europe. We also quantify the implications for optimal monetary policy: lowering inflation volatility becomes less costly in terms of GDP and unemployment volatility, which hints that optimal monetary policy may be more hawkish in an aging society. Finally, our results also propose a partial reversal of the European-US unemployment puzzle due to the fact that the share of young workers is expected to remain robust in the US.
Falcon stands out as a top-tier P2P Invoice Discounting platform in India, bridging esteemed blue-chip companies and eager investors. Our goal is to transform the investment landscape in India by establishing a comprehensive destination for borrowers and investors with diverse profiles and needs, all while minimizing risk. What sets Falcon apart is the elimination of intermediaries such as commercial banks and depository institutions, allowing investors to enjoy higher yields.
Empowering the Unbanked: The Vital Role of NBFCs in Promoting Financial Inclu...Vighnesh Shashtri
In India, financial inclusion remains a critical challenge, with a significant portion of the population still unbanked. Non-Banking Financial Companies (NBFCs) have emerged as key players in bridging this gap by providing financial services to those often overlooked by traditional banking institutions. This article delves into how NBFCs are fostering financial inclusion and empowering the unbanked.
where can I find a legit pi merchant onlineDOT TECH
Yes. This is very easy what you need is a recommendation from someone who has successfully traded pi coins before with a merchant.
Who is a pi merchant?
A pi merchant is someone who buys pi network coins and resell them to Investors looking forward to hold thousands of pi coins before the open mainnet.
I will leave the telegram contact of my personal pi merchant to trade with
@Pi_vendor_247
What price will pi network be listed on exchangesDOT TECH
The rate at which pi will be listed is practically unknown. But due to speculations surrounding it the predicted rate is tends to be from 30$ — 50$.
So if you are interested in selling your pi network coins at a high rate tho. Or you can't wait till the mainnet launch in 2026. You can easily trade your pi coins with a merchant.
A merchant is someone who buys pi coins from miners and resell them to Investors looking forward to hold massive quantities till mainnet launch.
I will leave the telegram contact of my personal pi vendor to trade with.
@Pi_vendor_247
how to sell pi coins in South Korea profitably.DOT TECH
Yes. You can sell your pi network coins in South Korea or any other country, by finding a verified pi merchant
What is a verified pi merchant?
Since pi network is not launched yet on any exchange, the only way you can sell pi coins is by selling to a verified pi merchant, and this is because pi network is not launched yet on any exchange and no pre-sale or ico offerings Is done on pi.
Since there is no pre-sale, the only way exchanges can get pi is by buying from miners. So a pi merchant facilitates these transactions by acting as a bridge for both transactions.
How can i find a pi vendor/merchant?
Well for those who haven't traded with a pi merchant or who don't already have one. I will leave the telegram id of my personal pi merchant who i trade pi with.
Tele gram: @Pi_vendor_247
#pi #sell #nigeria #pinetwork #picoins #sellpi #Nigerian #tradepi #pinetworkcoins #sellmypi
how to sell pi coins at high rate quickly.DOT TECH
Where can I sell my pi coins at a high rate.
Pi is not launched yet on any exchange. But one can easily sell his or her pi coins to investors who want to hold pi till mainnet launch.
This means crypto whales want to hold pi. And you can get a good rate for selling pi to them. I will leave the telegram contact of my personal pi vendor below.
A vendor is someone who buys from a miner and resell it to a holder or crypto whale.
Here is the telegram contact of my vendor:
@Pi_vendor_247
Turin Startup Ecosystem 2024 - Ricerca sulle Startup e il Sistema dell'Innov...Quotidiano Piemontese
Turin Startup Ecosystem 2024
Una ricerca de il Club degli Investitori, in collaborazione con ToTeM Torino Tech Map e con il supporto della ESCP Business School e di Growth Capital
how to sell pi coins in all Africa Countries.DOT TECH
Yes. You can sell your pi network for other cryptocurrencies like Bitcoin, usdt , Ethereum and other currencies And this is done easily with the help from a pi merchant.
What is a pi merchant ?
Since pi is not launched yet in any exchange. The only way you can sell right now is through merchants.
A verified Pi merchant is someone who buys pi network coins from miners and resell them to investors looking forward to hold massive quantities of pi coins before mainnet launch in 2026.
I will leave the telegram contact of my personal pi merchant to trade with.
@Pi_vendor_247
How to get verified on Coinbase Account?_.docxBuy bitget
t's important to note that buying verified Coinbase accounts is not recommended and may violate Coinbase's terms of service. Instead of searching to "buy verified Coinbase accounts," follow the proper steps to verify your own account to ensure compliance and security.
how can i use my minded pi coins I need some funds.DOT TECH
If you are interested in selling your pi coins, i have a verified pi merchant, who buys pi coins and resell them to exchanges looking forward to hold till mainnet launch.
Because the core team has announced that pi network will not be doing any pre-sale. The only way exchanges like huobi, bitmart and hotbit can get pi is by buying from miners.
Now a merchant stands in between these exchanges and the miners. As a link to make transactions smooth. Because right now in the enclosed mainnet you can't sell pi coins your self. You need the help of a merchant,
i will leave the telegram contact of my personal pi merchant below. 👇 I and my friends has traded more than 3000pi coins with him successfully.
@Pi_vendor_247
3. Personal Background
• Managing Partner of the Innovation Fund at
Partners HealthCare
• Started VC career in 1994
• Started several venture-backed companies
4. Venture Environment
• Declining VC investment in life sciences
– $$ invested in startups down 64% 2007-2012
– Only 11 new healthcare funds raised in 2012 (39 in
2006)
– Q1 2013 had the fewest initial investments in life
sciences since 1995 – down 75% since the 2007
peak
• Strategics stepping in earlier – but mainly for
therapeutics
9. How to identify commercial potential
• It depends
• Start at the end – what is the market need
• Market size
• Unmet medical need
• Competition
• Better faster cheaper is hard
• Path to market – cost to get there
• Need to have versus nice to have
• If you can’t understand the need, chances are the
opportunity is limited
10. Patenting
• Biomedical products require large investment to bring to market
• Public domain: what belongs to everyone belongs to no one
• Provisional patent filings act as placeholders for 1 year
• First utility filings typically run $25,000 legal fees
• Foreign filing typically $150,000 fees
• “Prophetic” patents generally not valued as much as reduction to practice
• Only a tiny fraction of patents issued ever generate revenue
11. Patent value
•Composition is better than method of use
• Breadth versus depth
• Product margin
• Stacking
•What do the claims really allow
• How developed is the underlying technology
•Freedom to operate versus patentability
12. How VCs value a startup
•Too early stage for traditional valuation methods like
discounted cash flow
•Use multiple methods
•Comparables
•Skip to the exit point and work backwards
•How much are later stage companies worth
•How much capital and in what form does it take to get
there
•Must fit general guidelines
•Competing term sheets exist but are rare
13. What is Due Diligence?
•Investor research to test the business plan
•Assumptions are challenged – support your assertions
with evidence
•Diligence process often reshapes the plan
•Emphasis on customer/purchaser/user interviews
•Expect 3-6 month process from start to closing
•Requires high effort from entrepreneurial team
14. FDA route? Data submission requirements? Clinical trial design? Budget?Regulatory Path
Existing or new CPT/ISDN9 code? Private pay? Incremental or replacement?Reimbursement
Exit path? Potential acquirers? ROI? Comparables?Exit
Capital raised to date? Sources? Timetable of cash requirements vs milestones. Cap table? Pro forma P&L with milestone
overlay? Pre-$ valuation and amount sought. Use of funds? Deal terms.
Financing
Team background? Directors? SAB? Staffing plan? Organizational structure? Operational plan?Management
Barriers to competition. Patent filings? Breadth and strength of claims? Prosecution status? Patentability analysis? Freedom
to operate assessment? License terms?
IP
Revenue sources? Product economics? COGS? Margin? Distribution costs? Partnering? Who benefits/who’s hurt?Business Model
Describe target market segments and adoption criteria. Develop market size model with unit volume, penetration
curve, pricing, etc. Go to market strategy ?
Market
Current and emerging players? Basis of sustainable advantage: compare features and performance characteristics.Competition
How is the product enabled? What is the underlying science and engineering? How is it different from the alternatives? Status
of technology development? Proof of principle? Publications? Validation? In vitro/in vivo data? Prototype available?
Technology
Describe the offering. What does the product/service do? How does it affect clinical decision making? How does is fit into
clinician workflow? What product does it replace? Historical genesis.
Product
What is the problem addressed? How does the solution satisfy the unmet need? Who values that? Cost/benefit?Value Proposition
Due Diligence Rubric
15. Therapeutics Devices Diagnostics HCIT
Time to market 10-12 years 2-5 years 2-8 years < 1 year
Time to exit ~5 years Significant sales ~5 years 2-5 years
Investment to
market
$250MM $10MM $25MM+ $0+
Investment to exit $100MM $30MM+ $25MM+ $5-50MM
FDA Major issue Increasing issue Increasing Usually nonissue
Reimbursement Limited exposure Important problem Important
problem
Generally not
reimbursed
Stage to show for
funding
Two years from
clinical, animal
data
Prototype with
evidence
Prospective data
analysis
Adoption
Market minimum
size
$350MM, $1B
better
$200MM, $1B
better
Varies, must be
large
$200MM
minimum
Leading risk Will it work and
can we get it
through FDA
Adoption rate Will it work well
enough to be
adopted
Adoption
Rules of Thumb
16. Medical Devices
• Require more capital than you think
• FDA is an increasing issue – current uncertainty
• Need to develop clinical data to convince skeptical MDs
to change their practice of medicine
• Reimbursement is a major challenge – new codes take
~2 years post-FDA approval
• Outsource R&D model – large device companies acquire
many more products than they develop
• Diligence around market need is key – slow adoption
kills companies
• Strong preference for therapeutic vs diagnostic devices