Ken Kesey was born in 1935 in Oregon and had a conventional upbringing, but he had a transformative experience in college when he moved to an unconventional neighborhood in California and volunteered for CIA-sponsored LSD experiments. This exposure to psychedelic drugs and unconventional thinkers inspired Kesey to write his acclaimed novel One Flew Over the Cuckoo's Nest. After its success, Kesey gathered a group of friends known as the Merry Pranksters and lived communally in California, promoting psychedelic and countercultural experiences through their activities.