The document discusses how understanding different audiences across platforms, practices, and content is crucial for digital publishers. It provides examples of how publishers can 1) tailor content and headlines for different platforms like mobile, web, and print that have distinct user mindsets and expectations, 2) evolve practices from a linear research-write-publish model to ongoing audience engagement, and 3) conduct audience analysis to improve content visibility, curation, and interaction. Specific tactics highlighted include A/B testing headlines and tones in emails, keyword research to cover audience interests, and surveying viewers about video preferences.