Jaundice is caused by high levels of bilirubin in the blood, which leads to yellowing of the skin and eyes. Bilirubin is produced from the breakdown of red blood cells and is normally processed by the liver and gallbladder. Common causes of jaundice include hepatitis, gallstones, and tumors, which can interfere with bilirubin processing or cause liver inflammation. Signs of jaundice include yellow skin and eyes, as well as potentially itchy skin, weight loss, abdominal pain, and joint inflammation depending on the underlying cause.

1. By – Saranjit Singha
Assistant Prof
JBIT College of Pharmacy

2. INTRODUCTION
• Jaundice is a condition in which the skin, whites of
the eyes and mucous membranes turn
yellow because of a high level of bilirubin, a yellow-
orange bile pigment. Jaundice has many causes,
including hepatitis, gallstones and tumors. Bile is
fluid secreted by the liver. Bilirubin is formed from
the breakdown of red blood cells

4. CAUSES OF JAUNDINCE

12. SIGN AND SYMPTOMS OF JAUNDICE

13. If jaundice isn't caused by an infection, you may have symptoms
such as weight loss or itchy skin (pruritus). If the jaundice is caused
by pancreatic or biliary tract cancers, the most common symptom is
abdominal pain. Sometimes, you may have jaundice occurring with
liver disease if you have:
• Chronic hepatitis or inflammation of the liver.
• Pyoderma gangrenosum (a type of skin disease).
• Acute hepatitis A B or C
• Polyarthralgias (inflammation of the joints)