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LESSON PLAN
                                 KLESCOPH
 SHRI.R.V.SAVADI
 SUBJECT: INDUSTRIAL PHARMACOGNOSY
 DEPARTMENT: PHARMACOGNOSY & PHYTOCHEMISTRY.



For more details visit:
http://www.ashwagandha.tk


CHAPTER: INTRODUCTION, IMPORTANCE AND STATUS OF HERBAL
MEDICINES AND COSMETICS.
No of hours required as per RGUHS syllabus: 3
No of hours required as per Lesson plan: 3

Prerequiste:

Student needs to understand the importance of herbal drugs.

OBJECTIVE:

      a) To know and understand significance of herbal medicines and
         cosmetics
      b) To be aware of plant based industries and institutions involved in
         work on medicinal and aromatic plants.

RESOURCES:

TEACHING AIDS
    a) Black Board and chalk pieces.
    b) OHP projector.

REFERENCES

      1.   Text of pharmacognosy by T.E. Wallis.
      2.   Text of pharmacognosy by Kokate and Purohit.
      3.   Pharmacognosy by S.S Honda and V.K.Kapoor.
      4.   Pharmacognosy by Trease and Evans

MODEL QUESTIONS:
2 marks questions
      1) Define Herbal medicines and cosmetics.
      2) Name marketed herbal cosmetics and their uses.
      3) Enlist various marketed herbal formulations along with their uses.
5 marks questions
4) Explain the significance and present status of herbal medicines and
         cosmetics?
      5) Give an account of plant based industries and institutions involved in
         work on medicinal and aromatic plants.

CHAPTER : PHYTO PHARMACEUTICALS
No of hours required as per RGUHS syllabus: 10
No of hours required as per Lesson plan: 12

PREREQUISITE:
Students need to know the general methods of Isolation, Identification and
Estimation of phytoconstituents.

OBJECTIVE:
      a) To know various methods available to isolate, identify and estimate
         phytoconstituents.
      b) To know possible modification that can be done to isolate, identify
         and estimate phytoconstituents.

RESOURCES:

TEACHING AIDS
    a) Black board and chalk piece
    b) OHP

REFERENCES

      1)   Pharmacognosy by Trease and Evans.
      2)   Pharmacognosy (Phtyochemistry of Medicinal plants) by J.Bruneton.
      3)   Modern methods of Plant analysis by Peach and Tracy.
      4)   Indian Herbal Pharamacopeia Vol I & II by CSIR,RRL.
      5)   Isolation and Identification of Drugs By Clarke.
      6)   Phytochemical methods by J.B.Harbone.
      7)   Standardization of Botanicals by Dr. V.Rajpal.

MODEL QUESTIONS:
2 marks questions.
      1.    Enlist general methods of isolation, identity and estimation of
            phytoconstituents.
      2.    Explain how modification can be done to the existing method to
            isolate a phytoconstituents.
      3.    Mention the identification tests for Rutin?
      4.    Give a method of isolation of Glycyrrhizin?
5 marks questions.
      1. Describe in detail the isolation and estimation of Quinine? 5
      2. Write the different methods of Estimation of Cardiac Glycosides? 5
10 marks questions.
1. Write in detail Isolation,Identification and Estimation of Calcium
       Sennsosides?
    2. Explain various methods available to Identify the following.
          a) Andrographolides b) Gymnemic acid c) Withanolides
          d) Asiaticoside e) Citrus bioflavonoids.
CHAPTER : HERBAL FORMULATIONS

No of hours required as per RGUHS syllabus: 6
No of hours required as per Lesson plan: 7

PREREQUISITE:

Students need to understand the basic concepts of AYUSH and Chinese
medicine.

OBJECTIVE:

      a) To understand the role of Herbs in Cosmetics.
      b) To understand the basic principles involved in the preparation of
         Formulation in Ayurveda.

RESOURCES:

TEACHING AIDS
    a) Black board and chalk piece
    b) OHP

REFERENCES

      1)   Glossary of Indian medicinal plants by R.N. Chopra.
      2)   Herbal Beauty products by Vaidy Asharan
      3)   Indian Ayudrvedic Pharmacopoeia
      4)   Ayurvedic formulary

MODEL QUESTIONS:

2 marks questions

      1) Give the basic principle of Ayurvedic system of medicine.
      2) How do Siddha and Unani Systems of medicine differ in their basic
         concepts?
5 marks questions
      1) Describe in detail the basic principle involved in Chinese and
         Homeopathy systems of medicines?
      2) Give the preparation of Aristas, Asava, Ghutica, Taila.
      3) Write a note on Role of herbs in Cosmetics with examples?
      4) Explain the preparation of Churna, Leha and Bhasma?
      5) Write in detail the role of Amla, Henna, Hibiscus, and Tea in
Formulation of Hair Conditioners?




CHAPTER : STANDARDISATION

No of hours required as per RGUHS syllabus: 12
No of hours required as per Lesson plan: 14

PREREQUISITE:

Students need to know the general methods of Standardization of Raw
materials extracts, and Formulations.

OBJECTIVE:

      a) To study various methods available to evaluate raw materials extracts,
         and Formulations.
      b) To understand WHO Guidelines for the assessment of Herbal
         preparations.
      c) To learn about modern methods available for analysis of herbal
         preparations.

RESOURCES:

TEACHING AIDS
    a) Black board and chalk piece
    b) OHP

REFERENCES

      1) Quality Control of Herbal Drugs By Dr.Pulok K. Mukherji.
      2) Pharmacognosy( Phtyochemistry of Medicinal plants) by J.Bruneton.
      3) Indian Herbal Pharamacopeia Vol I & II by CSIR,RRL.
      4) Standardization of Botanicals by Dr. V.Rajpal.
      5) Quality Control of Herbal Drugs by WHO Guidelines .
      6) Pharmacopeial Standards of Herbal Plants Vol I and II, By
         C.R.Karnick.
      7) WHO Guidelines Book

MODEL QUESTIONS:
2 marks questions
      1)   How do you standardize vasaka extract?
      2)   What is quantitative microscopy? Explain.
      3)   How do you identify Arsenic in herbal preparations?
      4)   How will you Standardize Punarnava extract?
5 marks questions
1) Write a note on importance of Standardization of Raw materials and
         Formulations with examples?
      2) Describe in detail WHO guidelines for assessment of crude drugs?
      3) Write a note on Standardization of crude drugs by HPLC and HPTLC
         with suitable examples?
      4) How will you determine the alcohol content in Aristas and Asavas?

10 marks questions

      1) Write a note on Standardization of following crude drugs.
            a) Ashwagandha
            b) Bhrami.
            c) Phyllanthus.
            d) Tinospora Cordifolia.
            e) Vasaca.
      2) Write a note on different methods used to detect and estimate the
         amount of Heavy metals in Herbal preparations?


CHAPTER : PATENTING OF NATURAL PRODUCTS

No of hours required as per RGUHS syllabus: 2
No of hours required as per Lesson plan: 2

PREREQUISITE:

Students need to know about patents.

OBJECTIVE:

To understand significance of patenting.

RESOURCES:

TEACHING AIDS
    a) Black board and chalk piece
    b) OHP

REFERENCES
    1) Patents by N. R. Subbaram
    2) Journal articles

MODEL QUESTIONS:

2 marks questions

      1) Define Patent? What are the salient features of Patents? 5
      2) How do you register for a patent? Explain.
      3) Given an account of different types of patents.
CHAPTER : PLANT BIOTECHNOLOGY

No of hours required as per RGUHS syllabus: 7
No of hours required as per Lesson plan: 10

PREREQUISITE:

Students need to know the basic applications of tissue culture.

OBJECTIVE:

      a) To learn different methods used to improve quality of medicinal
         plants.
      b) To study and understand various tissue culture techniques and their
         applications.

RESOURCES:

TEACHING AIDS
    a) Black board and chalk piece
    b) OHP
|
REFERENCES
    1) Pharmaceutical Biotechnology by Vyas and Dixit
    2) Cell biology by powar
    3) Biotechnology by mathur & purohit
    4) Biotechnology by mohan arora
    5) Pharmacognosy and Pharmacobiotechnology by J.E. Robbers & Tyler
    6) Tissue Culture and Plant Science by H.E. Street

MODEL QUESTIONS:

2 marks questions

      1) Elaborate the terms polyploidy, mutation and hybridization.
      2) Give an account of different classes of tissue culture.

5 marks questions

      1) Explain biotransformation and immobilization of cells and enzymes.
      2) Summarize various applications of plant biotechnology.
      3) Explain the commercial production of shikonin.

10 marks question

      1) Explain various methods available for Gene transfer in plants.
      2) How do you make use of various tissue culture techniques to increase
         the production of secondary metabolites?

CHAPTER : ENZYME BIOTECHNOLOGY
No of hours required as per RGUHS syllabus: 5
No of hours required as per Lesson plan: 7



PREREQUISITE:

Students need to know general information regarding enzymes.

OBJECTIVE:

      a) To study different methods available for isolation, purification of
         enzymes.
      b) To study method of preparation and applications of enzymes.

RESOURCES:

TEACHING AIDS
    a) Black board and chalk piece
    b) OHP

REFERENCES

      1) Pharmaceutical Biotechnology by Vyas and Dixit
      2) Pharmacognosy by Purohit
      3) Pharmaconosy by Trease and Evans

MODEL QUISTIONS:

2 marks questions

      1) What are enzymes? Give an account of their characters.
      2) Name different enzyme reactors with neat diagrams.

5 marks questions

      1) Explain the general methods for the isolation and purification of
         enzymes.
      2) Explain the applications of immobosised enzymes.
      3) Write notes on plant enzymes – Papain and Bromelain
      4) Explain the manufacture and applications of Streptokinase and
         Asparginase.
      5) Give the applications of enzymes in drug analysis and drug
         manufacture.


CHAPTER : STUDY OF TRADITIONAL DRUGS

No of hours required as per RGUHS syllabus: 3
No of hours required as per Lesson plan: 3
PREREQUISITE:

Students need to know general information regarding morphological features
and local names of traditional drugs.
OBJECTIVE:

To learn vernacular names, source, active constituents and uses of traditional
drugs.

RESOURCES:

TEACHING AIDS
    a) Black board and chalk piece
    b) OHP

REFERENCES

      1)   Indian Medicinal Plants by Kirtikar and Basu
      2)   Pharmacognosy by Trease and Evans.
      3)   Wealth of India
      4)   Glossary of Indian Medicinal Plants by R.N. Chopra
      5)   South Indian Medicinal Plants by Dr. Yoga Narsimhan

MODEL QUISTIONS:

2 marks questions

      1) Give the common &vernacular names, source, active constituents &
         uses of Tylophora and Apamarg.
      2) Write on Shelajit.
      3) Give active constituents uses of Bilva and Guduchi.
      4) Give vernacular names source and uses of Shatavari, Leshsun, Kavera
         & Gokhru.

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Iv b ph ind pharmacognosy vvb

  • 1. LESSON PLAN KLESCOPH SHRI.R.V.SAVADI SUBJECT: INDUSTRIAL PHARMACOGNOSY DEPARTMENT: PHARMACOGNOSY & PHYTOCHEMISTRY. For more details visit: http://www.ashwagandha.tk CHAPTER: INTRODUCTION, IMPORTANCE AND STATUS OF HERBAL MEDICINES AND COSMETICS. No of hours required as per RGUHS syllabus: 3 No of hours required as per Lesson plan: 3 Prerequiste: Student needs to understand the importance of herbal drugs. OBJECTIVE: a) To know and understand significance of herbal medicines and cosmetics b) To be aware of plant based industries and institutions involved in work on medicinal and aromatic plants. RESOURCES: TEACHING AIDS a) Black Board and chalk pieces. b) OHP projector. REFERENCES 1. Text of pharmacognosy by T.E. Wallis. 2. Text of pharmacognosy by Kokate and Purohit. 3. Pharmacognosy by S.S Honda and V.K.Kapoor. 4. Pharmacognosy by Trease and Evans MODEL QUESTIONS: 2 marks questions 1) Define Herbal medicines and cosmetics. 2) Name marketed herbal cosmetics and their uses. 3) Enlist various marketed herbal formulations along with their uses. 5 marks questions
  • 2. 4) Explain the significance and present status of herbal medicines and cosmetics? 5) Give an account of plant based industries and institutions involved in work on medicinal and aromatic plants. CHAPTER : PHYTO PHARMACEUTICALS No of hours required as per RGUHS syllabus: 10 No of hours required as per Lesson plan: 12 PREREQUISITE: Students need to know the general methods of Isolation, Identification and Estimation of phytoconstituents. OBJECTIVE: a) To know various methods available to isolate, identify and estimate phytoconstituents. b) To know possible modification that can be done to isolate, identify and estimate phytoconstituents. RESOURCES: TEACHING AIDS a) Black board and chalk piece b) OHP REFERENCES 1) Pharmacognosy by Trease and Evans. 2) Pharmacognosy (Phtyochemistry of Medicinal plants) by J.Bruneton. 3) Modern methods of Plant analysis by Peach and Tracy. 4) Indian Herbal Pharamacopeia Vol I & II by CSIR,RRL. 5) Isolation and Identification of Drugs By Clarke. 6) Phytochemical methods by J.B.Harbone. 7) Standardization of Botanicals by Dr. V.Rajpal. MODEL QUESTIONS: 2 marks questions. 1. Enlist general methods of isolation, identity and estimation of phytoconstituents. 2. Explain how modification can be done to the existing method to isolate a phytoconstituents. 3. Mention the identification tests for Rutin? 4. Give a method of isolation of Glycyrrhizin? 5 marks questions. 1. Describe in detail the isolation and estimation of Quinine? 5 2. Write the different methods of Estimation of Cardiac Glycosides? 5 10 marks questions.
  • 3. 1. Write in detail Isolation,Identification and Estimation of Calcium Sennsosides? 2. Explain various methods available to Identify the following. a) Andrographolides b) Gymnemic acid c) Withanolides d) Asiaticoside e) Citrus bioflavonoids. CHAPTER : HERBAL FORMULATIONS No of hours required as per RGUHS syllabus: 6 No of hours required as per Lesson plan: 7 PREREQUISITE: Students need to understand the basic concepts of AYUSH and Chinese medicine. OBJECTIVE: a) To understand the role of Herbs in Cosmetics. b) To understand the basic principles involved in the preparation of Formulation in Ayurveda. RESOURCES: TEACHING AIDS a) Black board and chalk piece b) OHP REFERENCES 1) Glossary of Indian medicinal plants by R.N. Chopra. 2) Herbal Beauty products by Vaidy Asharan 3) Indian Ayudrvedic Pharmacopoeia 4) Ayurvedic formulary MODEL QUESTIONS: 2 marks questions 1) Give the basic principle of Ayurvedic system of medicine. 2) How do Siddha and Unani Systems of medicine differ in their basic concepts? 5 marks questions 1) Describe in detail the basic principle involved in Chinese and Homeopathy systems of medicines? 2) Give the preparation of Aristas, Asava, Ghutica, Taila. 3) Write a note on Role of herbs in Cosmetics with examples? 4) Explain the preparation of Churna, Leha and Bhasma? 5) Write in detail the role of Amla, Henna, Hibiscus, and Tea in
  • 4. Formulation of Hair Conditioners? CHAPTER : STANDARDISATION No of hours required as per RGUHS syllabus: 12 No of hours required as per Lesson plan: 14 PREREQUISITE: Students need to know the general methods of Standardization of Raw materials extracts, and Formulations. OBJECTIVE: a) To study various methods available to evaluate raw materials extracts, and Formulations. b) To understand WHO Guidelines for the assessment of Herbal preparations. c) To learn about modern methods available for analysis of herbal preparations. RESOURCES: TEACHING AIDS a) Black board and chalk piece b) OHP REFERENCES 1) Quality Control of Herbal Drugs By Dr.Pulok K. Mukherji. 2) Pharmacognosy( Phtyochemistry of Medicinal plants) by J.Bruneton. 3) Indian Herbal Pharamacopeia Vol I & II by CSIR,RRL. 4) Standardization of Botanicals by Dr. V.Rajpal. 5) Quality Control of Herbal Drugs by WHO Guidelines . 6) Pharmacopeial Standards of Herbal Plants Vol I and II, By C.R.Karnick. 7) WHO Guidelines Book MODEL QUESTIONS: 2 marks questions 1) How do you standardize vasaka extract? 2) What is quantitative microscopy? Explain. 3) How do you identify Arsenic in herbal preparations? 4) How will you Standardize Punarnava extract? 5 marks questions
  • 5. 1) Write a note on importance of Standardization of Raw materials and Formulations with examples? 2) Describe in detail WHO guidelines for assessment of crude drugs? 3) Write a note on Standardization of crude drugs by HPLC and HPTLC with suitable examples? 4) How will you determine the alcohol content in Aristas and Asavas? 10 marks questions 1) Write a note on Standardization of following crude drugs. a) Ashwagandha b) Bhrami. c) Phyllanthus. d) Tinospora Cordifolia. e) Vasaca. 2) Write a note on different methods used to detect and estimate the amount of Heavy metals in Herbal preparations? CHAPTER : PATENTING OF NATURAL PRODUCTS No of hours required as per RGUHS syllabus: 2 No of hours required as per Lesson plan: 2 PREREQUISITE: Students need to know about patents. OBJECTIVE: To understand significance of patenting. RESOURCES: TEACHING AIDS a) Black board and chalk piece b) OHP REFERENCES 1) Patents by N. R. Subbaram 2) Journal articles MODEL QUESTIONS: 2 marks questions 1) Define Patent? What are the salient features of Patents? 5 2) How do you register for a patent? Explain. 3) Given an account of different types of patents.
  • 6. CHAPTER : PLANT BIOTECHNOLOGY No of hours required as per RGUHS syllabus: 7 No of hours required as per Lesson plan: 10 PREREQUISITE: Students need to know the basic applications of tissue culture. OBJECTIVE: a) To learn different methods used to improve quality of medicinal plants. b) To study and understand various tissue culture techniques and their applications. RESOURCES: TEACHING AIDS a) Black board and chalk piece b) OHP | REFERENCES 1) Pharmaceutical Biotechnology by Vyas and Dixit 2) Cell biology by powar 3) Biotechnology by mathur & purohit 4) Biotechnology by mohan arora 5) Pharmacognosy and Pharmacobiotechnology by J.E. Robbers & Tyler 6) Tissue Culture and Plant Science by H.E. Street MODEL QUESTIONS: 2 marks questions 1) Elaborate the terms polyploidy, mutation and hybridization. 2) Give an account of different classes of tissue culture. 5 marks questions 1) Explain biotransformation and immobilization of cells and enzymes. 2) Summarize various applications of plant biotechnology. 3) Explain the commercial production of shikonin. 10 marks question 1) Explain various methods available for Gene transfer in plants. 2) How do you make use of various tissue culture techniques to increase the production of secondary metabolites? CHAPTER : ENZYME BIOTECHNOLOGY
  • 7. No of hours required as per RGUHS syllabus: 5 No of hours required as per Lesson plan: 7 PREREQUISITE: Students need to know general information regarding enzymes. OBJECTIVE: a) To study different methods available for isolation, purification of enzymes. b) To study method of preparation and applications of enzymes. RESOURCES: TEACHING AIDS a) Black board and chalk piece b) OHP REFERENCES 1) Pharmaceutical Biotechnology by Vyas and Dixit 2) Pharmacognosy by Purohit 3) Pharmaconosy by Trease and Evans MODEL QUISTIONS: 2 marks questions 1) What are enzymes? Give an account of their characters. 2) Name different enzyme reactors with neat diagrams. 5 marks questions 1) Explain the general methods for the isolation and purification of enzymes. 2) Explain the applications of immobosised enzymes. 3) Write notes on plant enzymes – Papain and Bromelain 4) Explain the manufacture and applications of Streptokinase and Asparginase. 5) Give the applications of enzymes in drug analysis and drug manufacture. CHAPTER : STUDY OF TRADITIONAL DRUGS No of hours required as per RGUHS syllabus: 3 No of hours required as per Lesson plan: 3
  • 8. PREREQUISITE: Students need to know general information regarding morphological features and local names of traditional drugs. OBJECTIVE: To learn vernacular names, source, active constituents and uses of traditional drugs. RESOURCES: TEACHING AIDS a) Black board and chalk piece b) OHP REFERENCES 1) Indian Medicinal Plants by Kirtikar and Basu 2) Pharmacognosy by Trease and Evans. 3) Wealth of India 4) Glossary of Indian Medicinal Plants by R.N. Chopra 5) South Indian Medicinal Plants by Dr. Yoga Narsimhan MODEL QUISTIONS: 2 marks questions 1) Give the common &vernacular names, source, active constituents & uses of Tylophora and Apamarg. 2) Write on Shelajit. 3) Give active constituents uses of Bilva and Guduchi. 4) Give vernacular names source and uses of Shatavari, Leshsun, Kavera & Gokhru.