Meckels diverticulum (MD) are vestigial remnants of the omphalomesenteric duct found in the ileum in 1-2% of people. Rarely, MD can become inverted into the lumen of the small bowel and be a cause of anemia, intussusception, and abdominal pain.
The esophageal duplication cyst is a congenital defect of the digestive tract. It has an estimated prevalence of 0.012%, with higher predominance in males. Although it is a common fi nding in children, diagnosis of an esophageal duplication in adults is rare. Following ileal duplication, esophageal is the second most common duplication of the gastrointestinal tract, representing the 10-15% of all gastrointestinal duplication defects. For esophageal duplication, there are two main variants: cystic and tubular, the latter being the least common. They are usually developed during the third to fifth week of gestation due to failure of the vacuolar coalescence. Duplication cysts are commonly located in the distal third of the esophagus.Treatment should always be surgical, even at the asymptomatic stage
of disease, given the possibility of symptom development and complication appearance. Here we present a case of an adult patient presenting with an esophageal duplication cyst with a brief literature review.
Abstract
This case report describes the diagnosis and management of a large mesenteric cyst in a 55 year old lady who presented with abdominal distension & with mass in the left upper quadrant. Mesenteric cysts are rare, benign, abdominal tumors to which <1000 cases have been reported in the literature. While 40% of cases are incidental findings found either through physical examination or imaging, they can cause non-specific abdominal symptoms including pain, altered bowel habits, nausea/vomiting or anorexia. Less commonly, 10% of cases can present with bowel obstruction, volvulus, torsion or shock. In general, the lack of characteristic clinical and radiological features presents as a diagnostic difficulty.
The mainstay in imaging is computerized tomography (CT). CT identifies and helps aid the decision to pursue a laparoscopic or open laparotomy approach, where complete surgical resection is the ultimate goal. In our patient a CT Abdomen & Pelvis showed a large, loculated cystic mass measuring 30cm in cranio-caudal length and 16cm in the transverse and anterior/posterior diameter. While different approaches have been described in the literature to surgically resect such cysts, our approach was largely reflective of size and adherence to surrounding structures in this case. A laparotomy was performed using an upper mid-line 7 cm incision; 4500cc of fluid was aspirated from the cyst which was found to originate from the small bowel mesentery. A complete resection of the multi-loculated cystic sac was done that included the resection of the middle mesenteric vein. The post-operative period was uneventful. The patient was discharged on post-operative day 2. The Histopathology identified the mass as a multi-loculated peritoneal inclusion-type cyst.
This case report describes a 61-year-old male patient who presented with chronic abdominal pain and was found to have xanthogranulomatous cholecystitis (XGC), a rare inflammatory disease of the gallbladder, along with gallstones. Imaging studies revealed thickening of the gallbladder wall and a mass, concerning for possible gallbladder carcinoma. The patient underwent cholecystectomy and was found to have XGC pathology, characterized by lipid-laden macrophages and chronic inflammatory cells infiltrating the gallbladder wall. XGC is a benign condition that can be confused for gallbladder cancer. The patient's surgery and recovery were uncomplicated.
A 33-year-old woman presented with recurrent abdominal pain and jaundice. Imaging revealed a duodenal intussusception caused by a duodenal duplication cyst. Magnetic resonance imaging clearly depicted the cyst as the lead point for the intussusception and showed biliary dilatation. At surgery, a 4 cm cyst was removed from the duodenum. Histopathology confirmed it was a duodenal duplication cyst, a rare congenital anomaly usually diagnosed in childhood that can remain asymptomatic into adulthood.
Omental torsion: a rare cause of acute abdomenKETAN VAGHOLKAR
Torsion of the greater omentum is one of the rare causes of acute abdomen. However with an increase in the incidence of obesity in urban population there is a steady increase in the incidence of this rare and deceptive abdominal condition. The attending surgeon needs to be aware of this condition especially when confronted with an obese patient presenting as an acute abdomen. The paper reviews the etiopathogenesis and management of this rare condition.
Rupture of a Hydatid Cyst into the Bile Ductasclepiuspdfs
Cholestasis secondary to a cystobiliary communication is a rare complication associated with hepatic hydatidosis. The most established surgical procedure is the evacuation of the contents of the cyst (daughter cysts) without spills, sterilization of the cyst cavity with scolicide agents to prevent the dissemination of the hydatids to the peritoneal cavity, and cavity management (capitonnage) together with the closing of the communication.
This document discusses a case of intussusception in an adult patient presenting with vomiting and abdominal pain. An abdominal CT scan found the characteristic "target" appearance of intussusception on axial images and a "sausage-shaped bowel mass" on coronal images, allowing the radiologist to make a diagnosis of intussusception. CT is identified as the most accurate imaging modality for identifying intussusception in adults.
Successful Repeated CT-Guided Drainage Of Rectal Mucocele After LAleksandr Reznichenko
This document describes a case study of a rectal mucocele that was successfully treated with repeated CT-guided drainage after a patient underwent low anterior resection for rectal prolapse. A rectal mucocele developed as a fluid-filled cyst near the rectal stump that caused symptoms. It was drained multiple times under CT guidance, with catheters inserted each time. Analysis of the fluid indicated it was a rectal mucocele rather than an abscess. This case demonstrates that repeated CT-guided drainage can successfully treat a rectal mucocele in a patient who was not a candidate for surgical resection.
The esophageal duplication cyst is a congenital defect of the digestive tract. It has an estimated prevalence of 0.012%, with higher predominance in males. Although it is a common fi nding in children, diagnosis of an esophageal duplication in adults is rare. Following ileal duplication, esophageal is the second most common duplication of the gastrointestinal tract, representing the 10-15% of all gastrointestinal duplication defects. For esophageal duplication, there are two main variants: cystic and tubular, the latter being the least common. They are usually developed during the third to fifth week of gestation due to failure of the vacuolar coalescence. Duplication cysts are commonly located in the distal third of the esophagus.Treatment should always be surgical, even at the asymptomatic stage
of disease, given the possibility of symptom development and complication appearance. Here we present a case of an adult patient presenting with an esophageal duplication cyst with a brief literature review.
Abstract
This case report describes the diagnosis and management of a large mesenteric cyst in a 55 year old lady who presented with abdominal distension & with mass in the left upper quadrant. Mesenteric cysts are rare, benign, abdominal tumors to which <1000 cases have been reported in the literature. While 40% of cases are incidental findings found either through physical examination or imaging, they can cause non-specific abdominal symptoms including pain, altered bowel habits, nausea/vomiting or anorexia. Less commonly, 10% of cases can present with bowel obstruction, volvulus, torsion or shock. In general, the lack of characteristic clinical and radiological features presents as a diagnostic difficulty.
The mainstay in imaging is computerized tomography (CT). CT identifies and helps aid the decision to pursue a laparoscopic or open laparotomy approach, where complete surgical resection is the ultimate goal. In our patient a CT Abdomen & Pelvis showed a large, loculated cystic mass measuring 30cm in cranio-caudal length and 16cm in the transverse and anterior/posterior diameter. While different approaches have been described in the literature to surgically resect such cysts, our approach was largely reflective of size and adherence to surrounding structures in this case. A laparotomy was performed using an upper mid-line 7 cm incision; 4500cc of fluid was aspirated from the cyst which was found to originate from the small bowel mesentery. A complete resection of the multi-loculated cystic sac was done that included the resection of the middle mesenteric vein. The post-operative period was uneventful. The patient was discharged on post-operative day 2. The Histopathology identified the mass as a multi-loculated peritoneal inclusion-type cyst.
This case report describes a 61-year-old male patient who presented with chronic abdominal pain and was found to have xanthogranulomatous cholecystitis (XGC), a rare inflammatory disease of the gallbladder, along with gallstones. Imaging studies revealed thickening of the gallbladder wall and a mass, concerning for possible gallbladder carcinoma. The patient underwent cholecystectomy and was found to have XGC pathology, characterized by lipid-laden macrophages and chronic inflammatory cells infiltrating the gallbladder wall. XGC is a benign condition that can be confused for gallbladder cancer. The patient's surgery and recovery were uncomplicated.
A 33-year-old woman presented with recurrent abdominal pain and jaundice. Imaging revealed a duodenal intussusception caused by a duodenal duplication cyst. Magnetic resonance imaging clearly depicted the cyst as the lead point for the intussusception and showed biliary dilatation. At surgery, a 4 cm cyst was removed from the duodenum. Histopathology confirmed it was a duodenal duplication cyst, a rare congenital anomaly usually diagnosed in childhood that can remain asymptomatic into adulthood.
Omental torsion: a rare cause of acute abdomenKETAN VAGHOLKAR
Torsion of the greater omentum is one of the rare causes of acute abdomen. However with an increase in the incidence of obesity in urban population there is a steady increase in the incidence of this rare and deceptive abdominal condition. The attending surgeon needs to be aware of this condition especially when confronted with an obese patient presenting as an acute abdomen. The paper reviews the etiopathogenesis and management of this rare condition.
Rupture of a Hydatid Cyst into the Bile Ductasclepiuspdfs
Cholestasis secondary to a cystobiliary communication is a rare complication associated with hepatic hydatidosis. The most established surgical procedure is the evacuation of the contents of the cyst (daughter cysts) without spills, sterilization of the cyst cavity with scolicide agents to prevent the dissemination of the hydatids to the peritoneal cavity, and cavity management (capitonnage) together with the closing of the communication.
This document discusses a case of intussusception in an adult patient presenting with vomiting and abdominal pain. An abdominal CT scan found the characteristic "target" appearance of intussusception on axial images and a "sausage-shaped bowel mass" on coronal images, allowing the radiologist to make a diagnosis of intussusception. CT is identified as the most accurate imaging modality for identifying intussusception in adults.
Successful Repeated CT-Guided Drainage Of Rectal Mucocele After LAleksandr Reznichenko
This document describes a case study of a rectal mucocele that was successfully treated with repeated CT-guided drainage after a patient underwent low anterior resection for rectal prolapse. A rectal mucocele developed as a fluid-filled cyst near the rectal stump that caused symptoms. It was drained multiple times under CT guidance, with catheters inserted each time. Analysis of the fluid indicated it was a rectal mucocele rather than an abscess. This case demonstrates that repeated CT-guided drainage can successfully treat a rectal mucocele in a patient who was not a candidate for surgical resection.
Laparoscopic Excision of Foregut Duplication Cyst of StomachApollo Hospitals
Retroperitoneal gastric duplication cysts lined by ciliated columnar epithelium are extremely rare lesions and its presentation during adulthood is a diagnostic challenge for treating clinicians. This entity often resembles cystic pancreatic neoplasm, retroperitoneal cystic lesions and sometimes as an adrenal cystic neoplasm. Correct diagnosis on the basis of radiological investigation is difficult and histopathologic analysis. We report a case of gastric duplication cyst in a 16year old girl that mimicked as a retroperitoneal /pancreatic /adrenal cystic lesion and was successfully managed by laparoscopy.
Lipoma of the Small Intestine: A Cause for Intussusception in AdultsKETAN VAGHOLKAR
This case report describes a rare case of small intestinal intussusception in a 22-year-old male patient caused by a lipoma. Imaging including ultrasound and CT scan revealed the classic signs of intussusception and identified a likely lipoma as the cause. During surgery, an ileoileocolic intussusception was found and gently reduced, finding a submucosal lipoma as the pathological lead point. The involved intestinal segment containing the lipoma was resected. Histopathological examination confirmed the diagnosis of benign submucosal lipoma. The patient recovered well with no further symptoms.
Appleby operation for pancreatic cancer. Cancer de pancreas - tratamentoMarcel Autran Machado
We described a modified Appleby operation for locally advanced distal pancreatic cancer with compromised hepatic collateral flow that needed hepatic arterial revascularization, successfully accomplished by left external iliac-hepatic arterial bypass with Dacron prosthesis.
1. The document provides a pictorial review of abdominal radiograph findings to aid in interpretation.
2. Key findings discussed include patterns of bowel gas, which can indicate ileus, small bowel obstruction, or large bowel obstruction like sigmoid volvulus.
3. Other findings summarized are abdominal organ delineation, pathologic gas, calcifications, implanted devices, and foreign bodies. The review serves as a guide for systematic analysis of abdominal radiographs in the emergency department.
This case report describes a rare case of a giant mucinous cystadenoma of the appendix in a 51-year-old female who presented with symptoms of acute appendicitis. Imaging revealed a large tubular structure connected to the cecum. Surgery found a 12 cm mass involving the cecum, so a right hemicolectomy was performed. Pathology confirmed a mucinous cystadenoma with low-grade dysplasia. The report reviews 18 similar giant cystadenoma cases from the literature defined as over 10 cm. Giant cystadenomas more often presented in older patients as a palpable mass and usually required colectomy if involving the cecum.
CT angiography based Study of Variations in Coeliac Trunk and its surgical im...iosrjce
IOSR Journal of Dental and Medical Sciences is one of the speciality Journal in Dental Science and Medical Science published by International Organization of Scientific Research (IOSR). The Journal publishes papers of the highest scientific merit and widest possible scope work in all areas related to medical and dental science. The Journal welcome review articles, leading medical and clinical research articles, technical notes, case reports and others.
Introduction
Cutaneous metastases from abdominal malignancies are rare and have been reported in less than 5% of patients [1]. Furthermore, metastases in patients suffering from colorectal neoplasia are even rarer entity. Tan et al, among 2538 of the new cases of colorectal cancer over the period of 6 years, reported only 3 cases (0.1%) with cutaneous deposits [1]. Presentation varies from cutaneous or subcutaneous small nodules, rash or large fungating lesions [1-4]. Inevitably, their presence implies the disease progression, and poor prognosis with the reported survival between 1 to 34 months [2,3,5].
We report a case of an elderly patient who initially was thought to present with a simple skin infection. Subsequently, the patient was diagnosed with the moderately differentiated mucinous adenocarcinoma and required the right hemicolectomy. This case highlights that a high index of suspicion is recommended in an unresolving skin erythema.
“Little Old Ladies Hernia”: A Case Report and Review of Literature_Crimson Pu...CrimsonPublishersAICS
“Little Old Ladies Hernia”: A Case Report and Review
of Literature by Sonali Sethi*, Satyajit Godhi, Pankaj Kumar and Amit Javed in Advancements in Case Studies
This document discusses gastric carcinoma and gastric lymphoma. It begins with the epidemiology, risk factors, and routes of spread of gastric cancer. It then describes various radiological procedures used to image gastric carcinoma such as CT, MRI, PET, and barium studies. It discusses the radiographic and CT findings of early and advanced gastric cancers, including Borrmann classification correlated with CT findings. Lymph node metastasis and TNM staging criteria are also covered.
Isolated Splenic Metastases from Rectal Carcinoma Five Years after Surgery: C...semualkaira
Primary splenic tumors and splenic metastases are uncommon, and
metastatic splenic tumors are even rarer [1]. According to reports,
the most common source of splenic metastases include melanoma,
tumors of the breast, lung, ovary, colon, stomach, and pancreas [2-
3]. Splenic metastases after rectal cancer surgery is very rare. This
paper reports a case of a patient with splenic metastases from rectal cancer 5 years after surgery. We discuss the route of metastasis
and treatment of this case.
Malignant Transformation in A Case of Multiple Osteochondromas: Role of FDG P...submissionclinmedima
We present a 19-year-old man affected by osteochondromatosis since he aged 9. Multiple enchondromas showed asymmetric distribution of osseous and cartilage lesions with major deformities of pelvis and long bones and minor lesions in left scapula and few ribs.
A 60 year old male was referred to a tertiary referral centre with a chronic dry cough. He was a lifelong non-smoker. Clinical examination was unremarkable. AssessmentIGE, RAST to common allergens, eosinophils and alpha one anti-trypsin were within normal limits. Barium swallow did not show any oesophageal dysmotility, gastric outlet obstruction or reflux
Food Allergy in School-Going Adolescents and Its Association with Depression ...submissionclinmedima
The aim of thisstudy wasto document food allergy in school going adolescents and its association with depression. 1.2.Methods: An observational cross-sectionalstudy was conducted from 2016 to 2018 in middle income schools of Karachi after receiving institutional review board approval of Karachi Medical and Dental College (ref:020/16). Students, male and female, with age range of 11 to 17 years, were included. Students who refused to fill questionnaire were excluded
Symbrachydactyly is a unilateral hand anomaly with failure of formation of fingers and presence of rudimentary digits that include elements of nail plate, bone, and cartilage. Vascular dysgenesis and disruption of apical ectodermal ridge of developing limb bud are possible aetiologies
Physiologic Papillomatosis of the Penis Mimicking Genital War- ts: Role of De...submissionclinmedima
Physiologic papillomatosis of the penis is a benign, non-infectious affection that may be confused to genital warts and it is assimilated to the vestibular papillomatosis in the woman. A young man of 21 years old, came to our department with a history of non protected sexual activity.
Effect of Time of Echo on 1H-magnetic Resonance Spectroscopy Imaging of Metab...submissionclinmedima
The aim of this study is to evaluate the effect of time of echo (TE) on magnetic resonance spectroscopy imaging (MRSI) of metabolites in maxillofacial carcinoma. 1.2. Methods: Twenty maxillofacial carcinoma patients and 10 healthy volunteers were recruited to undergo 1.5-Tesla high-resolution routine MRI and multi-voxel MRSI with a TE of 35 ms and 144 ms.
Fragmented QRS Complex is associated with the Left Ventricular Remodeling in ...submissionclinmedima
A total of 140 patients with AMI were enrolled. Accoridng to the presence of fQRS in presenting electrocardiogram. The patients were divided into fQRS group and NonfQRS group. Real-time three-dimensional echocardiograph parameters measured in-hospital and 6-month follow-up period were collected.
We report a case of a 23 year old female with history of fever and malaise since 3 days. We received her blood sample for complete blood count along with peripheral blood smear examination. The blood test showed leukocytosis 23,500 cells/uL, Hemoglobin- 12.2 gm/dl and Platelet count 1, 58,000/Ul. The peripheral blood examination showed marked lymphocytosis with presence of 24% atypical lymphocytes along with 46% lymphocytes and 30% Neutrophils. Based on the peripheral blood examination..
A 39 year old right handed lady presented with a 3 month history of worsening chin and bilateral leg tremors. Secondary to this she had multiple falls.
Tenckhoff’s Catheter Recurrent Obstruction by Fallopian Tubesubmissionclinmedima
The incidence of end-stage kidney disease, in the Caucasian population, is 275 cases per 1 million people per year. Currently, nearly 10% of patients under renal replacement therapy are under peritoneal dialysis. The catheters dysfunction is generally caused by its displacement
The radiographic findings of tumoral calcinosis in a 2- years old girl with limping include periarticular ovaloid calcifications or calcified cysts with calcium layering in the dependent portion giving the appearance of sedimentation sign. Tumoral calcinosis is a rare condition in which there is calcium deposition in the soft tissue in periarticular location around joints.
Nanomedicine Approach for the Rapid Healing of Diabetic Foot Ulcers with Silv...submissionclinmedima
We present the use of silver nanoparticles (AgNPs) for 3 the treatment of Diabetic Foot Ulcers (DFU) of grade 2 and 3 of Wagner classification. 1.2. Methods: Ulcers were daily treated by topical administration of AgNPs (at 1.8mg/mL of metallic silver) in addition to conventional antibiotics.
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Laparoscopic Excision of Foregut Duplication Cyst of StomachApollo Hospitals
Retroperitoneal gastric duplication cysts lined by ciliated columnar epithelium are extremely rare lesions and its presentation during adulthood is a diagnostic challenge for treating clinicians. This entity often resembles cystic pancreatic neoplasm, retroperitoneal cystic lesions and sometimes as an adrenal cystic neoplasm. Correct diagnosis on the basis of radiological investigation is difficult and histopathologic analysis. We report a case of gastric duplication cyst in a 16year old girl that mimicked as a retroperitoneal /pancreatic /adrenal cystic lesion and was successfully managed by laparoscopy.
Lipoma of the Small Intestine: A Cause for Intussusception in AdultsKETAN VAGHOLKAR
This case report describes a rare case of small intestinal intussusception in a 22-year-old male patient caused by a lipoma. Imaging including ultrasound and CT scan revealed the classic signs of intussusception and identified a likely lipoma as the cause. During surgery, an ileoileocolic intussusception was found and gently reduced, finding a submucosal lipoma as the pathological lead point. The involved intestinal segment containing the lipoma was resected. Histopathological examination confirmed the diagnosis of benign submucosal lipoma. The patient recovered well with no further symptoms.
Appleby operation for pancreatic cancer. Cancer de pancreas - tratamentoMarcel Autran Machado
We described a modified Appleby operation for locally advanced distal pancreatic cancer with compromised hepatic collateral flow that needed hepatic arterial revascularization, successfully accomplished by left external iliac-hepatic arterial bypass with Dacron prosthesis.
1. The document provides a pictorial review of abdominal radiograph findings to aid in interpretation.
2. Key findings discussed include patterns of bowel gas, which can indicate ileus, small bowel obstruction, or large bowel obstruction like sigmoid volvulus.
3. Other findings summarized are abdominal organ delineation, pathologic gas, calcifications, implanted devices, and foreign bodies. The review serves as a guide for systematic analysis of abdominal radiographs in the emergency department.
This case report describes a rare case of a giant mucinous cystadenoma of the appendix in a 51-year-old female who presented with symptoms of acute appendicitis. Imaging revealed a large tubular structure connected to the cecum. Surgery found a 12 cm mass involving the cecum, so a right hemicolectomy was performed. Pathology confirmed a mucinous cystadenoma with low-grade dysplasia. The report reviews 18 similar giant cystadenoma cases from the literature defined as over 10 cm. Giant cystadenomas more often presented in older patients as a palpable mass and usually required colectomy if involving the cecum.
CT angiography based Study of Variations in Coeliac Trunk and its surgical im...iosrjce
IOSR Journal of Dental and Medical Sciences is one of the speciality Journal in Dental Science and Medical Science published by International Organization of Scientific Research (IOSR). The Journal publishes papers of the highest scientific merit and widest possible scope work in all areas related to medical and dental science. The Journal welcome review articles, leading medical and clinical research articles, technical notes, case reports and others.
Introduction
Cutaneous metastases from abdominal malignancies are rare and have been reported in less than 5% of patients [1]. Furthermore, metastases in patients suffering from colorectal neoplasia are even rarer entity. Tan et al, among 2538 of the new cases of colorectal cancer over the period of 6 years, reported only 3 cases (0.1%) with cutaneous deposits [1]. Presentation varies from cutaneous or subcutaneous small nodules, rash or large fungating lesions [1-4]. Inevitably, their presence implies the disease progression, and poor prognosis with the reported survival between 1 to 34 months [2,3,5].
We report a case of an elderly patient who initially was thought to present with a simple skin infection. Subsequently, the patient was diagnosed with the moderately differentiated mucinous adenocarcinoma and required the right hemicolectomy. This case highlights that a high index of suspicion is recommended in an unresolving skin erythema.
“Little Old Ladies Hernia”: A Case Report and Review of Literature_Crimson Pu...CrimsonPublishersAICS
“Little Old Ladies Hernia”: A Case Report and Review
of Literature by Sonali Sethi*, Satyajit Godhi, Pankaj Kumar and Amit Javed in Advancements in Case Studies
This document discusses gastric carcinoma and gastric lymphoma. It begins with the epidemiology, risk factors, and routes of spread of gastric cancer. It then describes various radiological procedures used to image gastric carcinoma such as CT, MRI, PET, and barium studies. It discusses the radiographic and CT findings of early and advanced gastric cancers, including Borrmann classification correlated with CT findings. Lymph node metastasis and TNM staging criteria are also covered.
Isolated Splenic Metastases from Rectal Carcinoma Five Years after Surgery: C...semualkaira
Primary splenic tumors and splenic metastases are uncommon, and
metastatic splenic tumors are even rarer [1]. According to reports,
the most common source of splenic metastases include melanoma,
tumors of the breast, lung, ovary, colon, stomach, and pancreas [2-
3]. Splenic metastases after rectal cancer surgery is very rare. This
paper reports a case of a patient with splenic metastases from rectal cancer 5 years after surgery. We discuss the route of metastasis
and treatment of this case.
Similar to Inverted Meckel’s Diverticulum: A Rare Cause of Chronic Anaemia (10)
Malignant Transformation in A Case of Multiple Osteochondromas: Role of FDG P...submissionclinmedima
We present a 19-year-old man affected by osteochondromatosis since he aged 9. Multiple enchondromas showed asymmetric distribution of osseous and cartilage lesions with major deformities of pelvis and long bones and minor lesions in left scapula and few ribs.
A 60 year old male was referred to a tertiary referral centre with a chronic dry cough. He was a lifelong non-smoker. Clinical examination was unremarkable. AssessmentIGE, RAST to common allergens, eosinophils and alpha one anti-trypsin were within normal limits. Barium swallow did not show any oesophageal dysmotility, gastric outlet obstruction or reflux
Food Allergy in School-Going Adolescents and Its Association with Depression ...submissionclinmedima
The aim of thisstudy wasto document food allergy in school going adolescents and its association with depression. 1.2.Methods: An observational cross-sectionalstudy was conducted from 2016 to 2018 in middle income schools of Karachi after receiving institutional review board approval of Karachi Medical and Dental College (ref:020/16). Students, male and female, with age range of 11 to 17 years, were included. Students who refused to fill questionnaire were excluded
Symbrachydactyly is a unilateral hand anomaly with failure of formation of fingers and presence of rudimentary digits that include elements of nail plate, bone, and cartilage. Vascular dysgenesis and disruption of apical ectodermal ridge of developing limb bud are possible aetiologies
Physiologic Papillomatosis of the Penis Mimicking Genital War- ts: Role of De...submissionclinmedima
Physiologic papillomatosis of the penis is a benign, non-infectious affection that may be confused to genital warts and it is assimilated to the vestibular papillomatosis in the woman. A young man of 21 years old, came to our department with a history of non protected sexual activity.
Effect of Time of Echo on 1H-magnetic Resonance Spectroscopy Imaging of Metab...submissionclinmedima
The aim of this study is to evaluate the effect of time of echo (TE) on magnetic resonance spectroscopy imaging (MRSI) of metabolites in maxillofacial carcinoma. 1.2. Methods: Twenty maxillofacial carcinoma patients and 10 healthy volunteers were recruited to undergo 1.5-Tesla high-resolution routine MRI and multi-voxel MRSI with a TE of 35 ms and 144 ms.
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A total of 140 patients with AMI were enrolled. Accoridng to the presence of fQRS in presenting electrocardiogram. The patients were divided into fQRS group and NonfQRS group. Real-time three-dimensional echocardiograph parameters measured in-hospital and 6-month follow-up period were collected.
We report a case of a 23 year old female with history of fever and malaise since 3 days. We received her blood sample for complete blood count along with peripheral blood smear examination. The blood test showed leukocytosis 23,500 cells/uL, Hemoglobin- 12.2 gm/dl and Platelet count 1, 58,000/Ul. The peripheral blood examination showed marked lymphocytosis with presence of 24% atypical lymphocytes along with 46% lymphocytes and 30% Neutrophils. Based on the peripheral blood examination..
A 39 year old right handed lady presented with a 3 month history of worsening chin and bilateral leg tremors. Secondary to this she had multiple falls.
Tenckhoff’s Catheter Recurrent Obstruction by Fallopian Tubesubmissionclinmedima
The incidence of end-stage kidney disease, in the Caucasian population, is 275 cases per 1 million people per year. Currently, nearly 10% of patients under renal replacement therapy are under peritoneal dialysis. The catheters dysfunction is generally caused by its displacement
The radiographic findings of tumoral calcinosis in a 2- years old girl with limping include periarticular ovaloid calcifications or calcified cysts with calcium layering in the dependent portion giving the appearance of sedimentation sign. Tumoral calcinosis is a rare condition in which there is calcium deposition in the soft tissue in periarticular location around joints.
Nanomedicine Approach for the Rapid Healing of Diabetic Foot Ulcers with Silv...submissionclinmedima
We present the use of silver nanoparticles (AgNPs) for 3 the treatment of Diabetic Foot Ulcers (DFU) of grade 2 and 3 of Wagner classification. 1.2. Methods: Ulcers were daily treated by topical administration of AgNPs (at 1.8mg/mL of metallic silver) in addition to conventional antibiotics.
Isolation and Characterization of a Novel Duck Hepatitis A Virus Genotype 3 i...submissionclinmedima
1. Researchers isolated and characterized a novel duck hepatitis A virus (DHAV) genotype 3 strain called HBGT/China/2014 from infected ducklings in Hebei Province, China.
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Primary lymphoma of the colon accounts for only 0.2-1.2% of all malignant colonic tumours. The gastrointestinal tract is affected in 30-40% of all primary extra-nodal lymphomas [1, 2]. Early diagnosis may preclude severe complications, such as perforation, haemorrhage or intestinal obstruction
Cryptococcosis; idiopathic CD4+ T-cell lymphocytopenia; Opportunistic Infections 2. Clinical Image A 50-year-old male with a past medical history of psoriasis presented with a two-week history of progressively worsening fatigue, low-grade fevers and throbbing frontal headaches, and several ulcerated papules of varying size (1-5mm) with central crusting and surrounding erythema noted on the forearms, chest, back and feet
A 54 year-old man, HIV seropositive since 2011, with highly active antiretroviral therapy (HAART) and a previous diagnosis of pulmonary tuberculosis presented with a history of fever, productive cough and weight loss of 15 days duration. Physical examination revealed a temperature of 38 °C, cachectic status, dyspnea, hemoptysis, tachycardia, and tachypnea and disseminated bilateral crackles.
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1) Poland Syndrome is a rare congenital disorder characterized by unilateral absence of chest wall muscles and abnormally short, webbed fingers on the same side. It occurs in 1 in 30,000 live births.
2) This case report describes a female newborn with left-sided absence of the pectoralis major muscle and a hypoplastic left nipple, but normal hands. This represents an atypical presentation of Poland Syndrome.
3) The cause of Poland Syndrome is unknown but may involve disruption of blood flow to the subclavian artery or tissues of the embryonic lateral plate mesoderm early in development. It can present variably from isolated muscle abnormalities to combined muscle and limb anomalies.
Intracerebral Mass and Medullary Compression Syndrome as Manifestation of HIV...submissionclinmedima
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The skin is the largest organ and its health plays a vital role among the other sense organs. The skin concerns like acne breakout, psoriasis, or anything similar along the lines, finding a qualified and experienced dermatologist becomes paramount.
Cell Therapy Expansion and Challenges in Autoimmune DiseaseHealth Advances
There is increasing confidence that cell therapies will soon play a role in the treatment of autoimmune disorders, but the extent of this impact remains to be seen. Early readouts on autologous CAR-Ts in lupus are encouraging, but manufacturing and cost limitations are likely to restrict access to highly refractory patients. Allogeneic CAR-Ts have the potential to broaden access to earlier lines of treatment due to their inherent cost benefits, however they will need to demonstrate comparable or improved efficacy to established modalities.
In addition to infrastructure and capacity constraints, CAR-Ts face a very different risk-benefit dynamic in autoimmune compared to oncology, highlighting the need for tolerable therapies with low adverse event risk. CAR-NK and Treg-based therapies are also being developed in certain autoimmune disorders and may demonstrate favorable safety profiles. Several novel non-cell therapies such as bispecific antibodies, nanobodies, and RNAi drugs, may also offer future alternative competitive solutions with variable value propositions.
Widespread adoption of cell therapies will not only require strong efficacy and safety data, but also adapted pricing and access strategies. At oncology-based price points, CAR-Ts are unlikely to achieve broad market access in autoimmune disorders, with eligible patient populations that are potentially orders of magnitude greater than the number of currently addressable cancer patients. Developers have made strides towards reducing cell therapy COGS while improving manufacturing efficiency, but payors will inevitably restrict access until more sustainable pricing is achieved.
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Inverted Meckel’s Diverticulum: A Rare Cause of Chronic Anaemia
1. Inverted Meckel’s Diverticulum: A Rare Cause of Chronic Anae-
mia
Craig S and Pasieka JL*
Department of Surgery, University of Calgary, Alberta, Canada
Volume 1 Issue 3- 2018
Received Date: 17 Oct 2018
Accepted Date: 15 Nov 2018
Published Date: 19 Nov 2018
1. Abstract
Meckel’s diverticulum (MD) are vestigial remnants of the omphalomesenteric duct found in the
ileum in 1-2% of people. Rarely, MD can become inverted into the lumen of the small bowel and
be a cause of anemia, intussusception, and abdominal pain. The radiological appearance of an
inverted MD is similar to that of a submucosal lipoma or pedunculated polyp. The non-specific
clinical and imaging features of an inverted MD make definitive pre-operative diagnosis difficult,
and as such, clinicians should be aware of the presentationand appearance of this interesting con-
genital anomaly.
Journal of Clinical and Medical
Images and Short Reports
Citation: Craig S and Pasieka JL, Inverted Meckel’s Diverticulum: A Rare Cause of Chronic Anaemia. 2018;
1(3ss): 1-2.
United Prime Publications: http://unitedprimepub.com
*Corresponding Author (s): Janice L Pasieka, Department of Surgery, University of Cal-
gary, Canada, Tel:+1 403-944-2491; Fax: +1 403-283-4130; E-mail: Janice.pasieka@ahs.ca
Case Report
2. Key words
Inverted meckel; S diverticu-
lum; Intussusception; Gastro-
intestinal bleeding; Enterog-
raphy
3. Case
A 47-year-old male was referred to our neuroendocrine tumor
(NET) clinic because of an imaging finding consistent with a sub
mucosal tumor of the small bowel. The patient was found to have
iron deficiency anemia on routine blood tests by his family doc-
tor earlier 4 years earlier. On further evaluation, he was found
to be FIT positive, but upper, lower and capsule endoscopy were
unable to demonstrate a cause of occult gastrointestinal blood
loss [1]. A CT enterography at that time demonstrated a 5cm
smooth and elongated sub mucosal lesion in the proximal ileum,
of which the differential diagnosis included small bowel NET,
pedunculated polyp and benign lipoma.
4. Introduction
Serum chromogranin A, urinary 5-HIAA, and an octreotide
scan were all negative, effectively excluding a small bowel NET.
A repeat of his cross-sectional imaging demonstrated that the
lesion had increased in size from 5cm to 8cm parallel to the long
axis of intestine, and was now associated with a small degree of
non-obstructing intussusception (Figure 1). At this time it was
felt that the lesion was acting as a lead point for the intussus-
ception, and that mucosal ulceration in the region of the intus-
susception was possibly causing occult gastrointestinal bleeding.
Therefore, a decision was made to perform a laparoscopic small
bowel resection.
During laparoscopy, an intussuscepted segment of small bowel
was identified in the proximal ileum approximately 90cm from
the ileocolic valve (Figure 2). The intussusception was reduced,
and a soft, non-obstructing mass was evident within the lumen
of the intussuscepted bowel segment. The small bowel was exter-
iorized via a 5cm mini-laparotomy and the segment containing
the mass lesion resected, and bowel continuity restored. The
specimen was opened to reveal an inverted and ulcerated MD
within the lumen of the small bowel (Figure 3). The MD meas-
ured approximately 6cm x 1.5cm, and had a large mucosal ulcer
on its mid-portion as well as a smaller ulcer at the tip.
Figure 1: Coronal view of CT abdomen.
Description: An 8cm intra-luminal and fat-attenuation lesion is demonstrated
within the proximal ileum.
Figure 2: Laparoscopic image of the ileo-ileal intussusception Description: On
running the small bowel, this ileo-ileal intussusception was discovered approx-
imately 90cm from the ileocolic valve. A palpable mass was evident in bowel
segment just to the left of the intussusception.