‘Vignettes of Introspection’ is a collective effort of young authors from various disciplines of society providing the content matter for the blog. The blog provides information on variety of topics with respect to its main theme of observing and understanding oneself.
The blog is public and accessible throughout the world in every possible format.
‘Vignettes of Introspection’ is devoted to people who wish to seek the essence of truth in their Life. The Raison d’être and the collective consciousness about the reality of things. The contents posted in the site is the work of its authors in their perspective view and therefore any resemblance to any work done by anyone, anywhere would be just a co-incidence and VoI bears no responsibility
for the same.
A great concern has been voiced in recent years over the extensive use of energy, the limited supply of resources, and the pollution of the environment from the use of present energy conversion systems. Electrical power accounts for much of the
energy consumed. Much of this power is wasted during transmission from power plant generators to the consumer. The
resistance of the wire used in the electrical grid distribution system causes a loss of 26-30% of the energy generated. This loss implies that our present system of electrical distribution is only 70-74% efficient.
Nikola Tesla is best known for his remarkable statements regarding the wireless transmission of electrical power. His first efforts towards this end started in 1891 and were intended to simply "disturb the electrical equilibrium in the nearby portions of the earth... to bring into operation in any way some instrument." In other words the object of his experiments was simply to produce effects locally and detect them at a distance.
Wireless Power Transmission Using Solar Power System elprocus
The main function of wireless power transfer is to allow electrical devices to be continuously
charged and lose the constraint of a power cord. This whole idea was developed by Nicolas
Tesla in 1893, where he developed a system of illuminating vacuum bulbs using wireless
transmission technique.
Presented at the International Conference on Identity Studies in Vienna, Austria.
http://socialsciencesandhumanities.com/upcoming-conferences-call-for-papers/international-conference-on-identity-studies/index.html
In this module, you will journey to the very heart of this course: Philosophy as a subject presents various philosophers offering multiple perspectives on just about any topic including the self. Philosophically, discussion of the self is a basic search for meaning and purpose in life. Determination, rationalization, and identification of the self-set the direction from which an individual travel to fulfill his or her purpose in life. The inability to define oneself leads to a lot of contradictions within the self later on; hence, it is one of the many imperatives in life to know oneself and to go on with the business of leading a life charted by oneself.
Does language create consciousness? This presentation explores this assertion and possible ways of improving the presentation of technical information.
A great concern has been voiced in recent years over the extensive use of energy, the limited supply of resources, and the pollution of the environment from the use of present energy conversion systems. Electrical power accounts for much of the
energy consumed. Much of this power is wasted during transmission from power plant generators to the consumer. The
resistance of the wire used in the electrical grid distribution system causes a loss of 26-30% of the energy generated. This loss implies that our present system of electrical distribution is only 70-74% efficient.
Nikola Tesla is best known for his remarkable statements regarding the wireless transmission of electrical power. His first efforts towards this end started in 1891 and were intended to simply "disturb the electrical equilibrium in the nearby portions of the earth... to bring into operation in any way some instrument." In other words the object of his experiments was simply to produce effects locally and detect them at a distance.
Wireless Power Transmission Using Solar Power System elprocus
The main function of wireless power transfer is to allow electrical devices to be continuously
charged and lose the constraint of a power cord. This whole idea was developed by Nicolas
Tesla in 1893, where he developed a system of illuminating vacuum bulbs using wireless
transmission technique.
Presented at the International Conference on Identity Studies in Vienna, Austria.
http://socialsciencesandhumanities.com/upcoming-conferences-call-for-papers/international-conference-on-identity-studies/index.html
In this module, you will journey to the very heart of this course: Philosophy as a subject presents various philosophers offering multiple perspectives on just about any topic including the self. Philosophically, discussion of the self is a basic search for meaning and purpose in life. Determination, rationalization, and identification of the self-set the direction from which an individual travel to fulfill his or her purpose in life. The inability to define oneself leads to a lot of contradictions within the self later on; hence, it is one of the many imperatives in life to know oneself and to go on with the business of leading a life charted by oneself.
Does language create consciousness? This presentation explores this assertion and possible ways of improving the presentation of technical information.
Based upon Scott B. Rae's Moral Choices. This is designed to be a simplified and accessible aid for Christians interested in exploring contemporary moral issues from a biblical perspective.
I conduct a workshop on Social Design & Design for Social Design at Design and Business Schools. This one was conducted at the India campus of Lécole de design Nantes Atlantique, in Bangalore, with the students of the Transcultural Design class.
This pdf is about the Schizophrenia.
For more details visit on YouTube; @SELF-EXPLANATORY;
https://www.youtube.com/channel/UCAiarMZDNhe1A3Rnpr_WkzA/videos
Thanks...!
Introduction:
RNA interference (RNAi) or Post-Transcriptional Gene Silencing (PTGS) is an important biological process for modulating eukaryotic gene expression.
It is highly conserved process of posttranscriptional gene silencing by which double stranded RNA (dsRNA) causes sequence-specific degradation of mRNA sequences.
dsRNA-induced gene silencing (RNAi) is reported in a wide range of eukaryotes ranging from worms, insects, mammals and plants.
This process mediates resistance to both endogenous parasitic and exogenous pathogenic nucleic acids, and regulates the expression of protein-coding genes.
What are small ncRNAs?
micro RNA (miRNA)
short interfering RNA (siRNA)
Properties of small non-coding RNA:
Involved in silencing mRNA transcripts.
Called “small” because they are usually only about 21-24 nucleotides long.
Synthesized by first cutting up longer precursor sequences (like the 61nt one that Lee discovered).
Silence an mRNA by base pairing with some sequence on the mRNA.
Discovery of siRNA?
The first small RNA:
In 1993 Rosalind Lee (Victor Ambros lab) was studying a non- coding gene in C. elegans, lin-4, that was involved in silencing of another gene, lin-14, at the appropriate time in the
development of the worm C. elegans.
Two small transcripts of lin-4 (22nt and 61nt) were found to be complementary to a sequence in the 3' UTR of lin-14.
Because lin-4 encoded no protein, she deduced that it must be these transcripts that are causing the silencing by RNA-RNA interactions.
Types of RNAi ( non coding RNA)
MiRNA
Length (23-25 nt)
Trans acting
Binds with target MRNA in mismatch
Translation inhibition
Si RNA
Length 21 nt.
Cis acting
Bind with target Mrna in perfect complementary sequence
Piwi-RNA
Length ; 25 to 36 nt.
Expressed in Germ Cells
Regulates trnasposomes activity
MECHANISM OF RNAI:
First the double-stranded RNA teams up with a protein complex named Dicer, which cuts the long RNA into short pieces.
Then another protein complex called RISC (RNA-induced silencing complex) discards one of the two RNA strands.
The RISC-docked, single-stranded RNA then pairs with the homologous mRNA and destroys it.
THE RISC COMPLEX:
RISC is large(>500kD) RNA multi- protein Binding complex which triggers MRNA degradation in response to MRNA
Unwinding of double stranded Si RNA by ATP independent Helicase
Active component of RISC is Ago proteins( ENDONUCLEASE) which cleave target MRNA.
DICER: endonuclease (RNase Family III)
Argonaute: Central Component of the RNA-Induced Silencing Complex (RISC)
One strand of the dsRNA produced by Dicer is retained in the RISC complex in association with Argonaute
ARGONAUTE PROTEIN :
1.PAZ(PIWI/Argonaute/ Zwille)- Recognition of target MRNA
2.PIWI (p-element induced wimpy Testis)- breaks Phosphodiester bond of mRNA.)RNAse H activity.
MiRNA:
The Double-stranded RNAs are naturally produced in eukaryotic cells during development, and they have a key role in regulating gene expression .
Richard's aventures in two entangled wonderlandsRichard Gill
Since the loophole-free Bell experiments of 2020 and the Nobel prizes in physics of 2022, critics of Bell's work have retreated to the fortress of super-determinism. Now, super-determinism is a derogatory word - it just means "determinism". Palmer, Hance and Hossenfelder argue that quantum mechanics and determinism are not incompatible, using a sophisticated mathematical construction based on a subtle thinning of allowed states and measurements in quantum mechanics, such that what is left appears to make Bell's argument fail, without altering the empirical predictions of quantum mechanics. I think however that it is a smoke screen, and the slogan "lost in math" comes to my mind. I will discuss some other recent disproofs of Bell's theorem using the language of causality based on causal graphs. Causal thinking is also central to law and justice. I will mention surprising connections to my work on serial killer nurse cases, in particular the Dutch case of Lucia de Berk and the current UK case of Lucy Letby.
Observation of Io’s Resurfacing via Plume Deposition Using Ground-based Adapt...Sérgio Sacani
Since volcanic activity was first discovered on Io from Voyager images in 1979, changes
on Io’s surface have been monitored from both spacecraft and ground-based telescopes.
Here, we present the highest spatial resolution images of Io ever obtained from a groundbased telescope. These images, acquired by the SHARK-VIS instrument on the Large
Binocular Telescope, show evidence of a major resurfacing event on Io’s trailing hemisphere. When compared to the most recent spacecraft images, the SHARK-VIS images
show that a plume deposit from a powerful eruption at Pillan Patera has covered part
of the long-lived Pele plume deposit. Although this type of resurfacing event may be common on Io, few have been detected due to the rarity of spacecraft visits and the previously low spatial resolution available from Earth-based telescopes. The SHARK-VIS instrument ushers in a new era of high resolution imaging of Io’s surface using adaptive
optics at visible wavelengths.
Earliest Galaxies in the JADES Origins Field: Luminosity Function and Cosmic ...Sérgio Sacani
We characterize the earliest galaxy population in the JADES Origins Field (JOF), the deepest
imaging field observed with JWST. We make use of the ancillary Hubble optical images (5 filters
spanning 0.4−0.9µm) and novel JWST images with 14 filters spanning 0.8−5µm, including 7 mediumband filters, and reaching total exposure times of up to 46 hours per filter. We combine all our data
at > 2.3µm to construct an ultradeep image, reaching as deep as ≈ 31.4 AB mag in the stack and
30.3-31.0 AB mag (5σ, r = 0.1” circular aperture) in individual filters. We measure photometric
redshifts and use robust selection criteria to identify a sample of eight galaxy candidates at redshifts
z = 11.5 − 15. These objects show compact half-light radii of R1/2 ∼ 50 − 200pc, stellar masses of
M⋆ ∼ 107−108M⊙, and star-formation rates of SFR ∼ 0.1−1 M⊙ yr−1
. Our search finds no candidates
at 15 < z < 20, placing upper limits at these redshifts. We develop a forward modeling approach to
infer the properties of the evolving luminosity function without binning in redshift or luminosity that
marginalizes over the photometric redshift uncertainty of our candidate galaxies and incorporates the
impact of non-detections. We find a z = 12 luminosity function in good agreement with prior results,
and that the luminosity function normalization and UV luminosity density decline by a factor of ∼ 2.5
from z = 12 to z = 14. We discuss the possible implications of our results in the context of theoretical
models for evolution of the dark matter halo mass function.
Seminar of U.V. Spectroscopy by SAMIR PANDASAMIR PANDA
Spectroscopy is a branch of science dealing the study of interaction of electromagnetic radiation with matter.
Ultraviolet-visible spectroscopy refers to absorption spectroscopy or reflect spectroscopy in the UV-VIS spectral region.
Ultraviolet-visible spectroscopy is an analytical method that can measure the amount of light received by the analyte.
3. INTRODUCTION
To explain and explore the meaning of things like life, consciousness,
experiences, realities, spiritual learning, universal truths, concepts which
are not documented and researched upon.
We are trying to discover as a team these phenomena’s which are
omnipresent and practically known to us but not understood in depth.
VOI writes on four genres:
META PHYSICS(mind and matter)
NOETIC SCIENCE (consciousness and reality)
ANTHROPOSOPHY (spirituality and experiences)
COSMOS (space and time)
4. META PHYSICS
This is a branch of philosophy which attempts to clarify the fundamental
notions by which people understand the world
e.g. existence, objects, with their properties, space and time, cause and effect,
reasons and possibility.
Basically its an investigation into the basic categories of being and how they
relate to each other
5. NOETIC SCIENCE
Noetics is a branch of metaphysical philosophy concerned with the study of
mind and intellectual to inspect the consciousness and realities of the practical
world
6. ANTHROPOSOPHY
This is a branch of Philosophy which postulates the existence of an objective,
intellectually comprehensible spiritual world accessible to direct experience
through inner development.
It aims to develop faculties of perceptive imagination, inspiration and intuition
through cultivating a form of thinking independent of sensory experience and
to present the results thus derived in a manner subject to rational verification
7. COSMOS
Cosmos is basically Universe with respect to two mediums of space and time.
Everything outside the ecosystem we live in is confined in as Cosmos.
8. MEMORANDUM OF ASSOCIATION
Vignettes Of Introspection working is governed by two bodies
VOICE (Vignettes Of Introspection Council of Editors).
VOILA (Vignettes Of Introspection Legislative Association).
The Board Meetings are chaired with the Pioneer of Vignettes of Introspection
holding rights to finalise the verdicts.
9. V.O.I.C.E
Vignettes Of Introspection Council of Editors is the body of authors, writers,
bloggers and associate editors led by the Editor-in-chief.
Their duty is to update the blog with new posts and research contents.
Their aim is to keep the editors team motivated.
VOICE is responsible for the content of the blog and co-ordinates with
VOILA, for promotion of posts.
10. V.O.I.L.A.
Vignettes Of Introspection Legislative Association is the body of content co-
ordinator, analysts, web designers, social promoters, led by the Marketing
Director.
Their duty is to promote the blog.
Their aim is to lead the market space and maintain the standard.
VOILA is responsible for the marketing of the blog and co-ordinates with
VOICE, for content.
12. AIMS
• To promote Vignettes Of Introspection
• Create awareness about the Blog
• Make it a place where people can share their thoughts with wide
range of online audience
• Build the team of writers
• To be one of the leading blog
13. PROCEDURE
• Spend considerable and consistent time and money on promotion
• Build a good image in minds of individuals and groups
14. MARKETING MEDIA
• Social media
• Word of mouth
• Online promotion on live websites
• Concerts
• Contests
• Public Relations (PR)