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DR REKHA KHARE
MD RADIOLOGY
 A young man was referred from
neurology OPD for MRI cervical spine
with the complaints of numbness of
left arm, for last six months
 Neurological exam. revealed normal
higher mental and cranial nerve function
 No motor power loss is noticed in left
arm, grip was normal
 X-ray cervical spine - AP and Lateral
view shows nothing significant
 Routine Lab examination was found with
in normal limit
 All standard sequences were taken
 Non contrast MRI revealed an relatively well
defined cystic nodular intramedullary hypo
intense lesion on T1W1 sequence with hyper
intense nidus lesion in the center at
C2-3 level
 Lesion gets hyper intense on T2 W1
sequence with mild hyper density in
surrounding area
 Contrast MRI shows:
A Ring enhanced lesion with central
enhanced nidus and moderate
perilesional oedma
 Minimal focal syrinx at the level of lesion
 Ring enhanced lesion: commonest
Tuberculoma and Neurocysticercosis
 Other Intramedullary cystic lesion:
infection/ abscess,
arachnoid cyst,ependymal cyst,
neurentric cyst, sarcoidosis,neoplasm
 Our case was straight forward case of
Intramedullary Cysticercosis –
Ring enhanced lesion with pin
point dot calcification in the
center and oedma in surrounding
tissue
** focal syrinx could be the possible reason of
the only symptom of Numbness
 Cysticercosis is a parasitic disease caused by
larval stage of Taenia solium
 Cysticercosis in human is first described in
1550 by Pranoli
 Cysticercosis is endemic in Indian
subcontinent
 Commonly cysticercosis occurs due to either
ingestion of contaminated vegetables, eaten
raw or oral-faecal route
 Disease is not restricted to the pork eater
who usually harbour the adult parasite
 Cysticercosis CNS is common in poor
developing region esp. in pediatric age
group
 Incidence of neurocysticercosis is about
4% of the general population
 Isolated Spinal intramedullary cysticercosis
is quite rare compared to spinal
subarachnoid cysticercosis
 It has been described very little. The
proposed mechanism of spread is
hematogenous dissemination
 As thoracic cord receives maximum blood so
it is most commonly affected
 Most Possible pathogenesis through
ventriculo-ependymal spread by migration of
larva from ventricle along CSF down to spinal
subarachnoid space
 Majority of cysticerci can not pass through
the subarachnoid space at the cervical level
due to its size and physiological sieve
 Cyst may increase with in cord and so
produce symptoms like that of small syrinx
 Toxic effects include local inflammation
secondary to leakage of parasitic metabolic
by product with in the cyst fluid
 Vascular compromise secondarily results in
cord ischemia and myelomalacia
Tuberculoma
 Irregular in shape
 Solid
 Ring enhanced lesion
more than 2cm
 Severe perilesional
oedma with mass
effect/ focal
neurological deficit
 TB else where
Neurocysticercosis
 Round
 Cystic
 Ring enhanced lesion
less than 2cm with
visible scolex/nidus..
Target lesion
 Perilesional oedma
not enough to
produce mass effect
 Intramedullary cysticercosis represents a
diagnostic challenge
 TARGET LESION: Ring enhanced small
lesion with pin point dense center/scolex
and usually with mild perilesional oedma is
quite characteristic
 it should be strongly considered in low
socio- economic poor developing area
 Major cause of adult onset Epilepsy
in the developing world
 CNS and eye involvement is termed as
Neurocysticercosis
 Predilection for migration to eyes, CNS and
striated muscle probably due to increased
glycogen and glucose content of these tissue
 Radiological staging:
visible cyst with scolex
degenerating cyst
calcified cyst
 Bin Qi,Pengfei Ge, Hongfa Yang, Chunhua Bi and
YipingLi. Spinal Intramedullary Cysticercosis: A
case Report and Literature Review: Int J Med Sci
2011;8(5)420-423
 Kumar S, Handa A, Chavda S. et al.
Intramedullary cysticercosis. J Clin
Neurosci.2010;17(4): 522-3[pub med]
 Lt Col PK Sahoo. Spinal Intramedullary
Cysticercosis.MJAFI2000,56:240-241
 Mathuria SN, Khosla VK, Vasistha RK et al
Intramedullary cysticercosis;MRI diagnosis.Neurol
India.2001;49(10: 71-4[pub med]
 Shubhangi V Agale, Shweta Bhavsar and Vidhya
Manohar: Isolated intramedullary spinal cord
cysticercosis. Asian J Neurosurg.2012 Apr-
Jun;7(2):90-92
 Singh p, Sahai K. Intramedullary cysticercosis.
NeurolIndia 2004:52:264-5(pub Med)
 Taveras JM,Wood Eh. Diagnostic neuro radiology.
2nd
ed.Baltimore The Williams and Wilkins
company 1977:1162
HAVE A NICE DAY

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Intramedullary neurocysticercosis

  • 1. DR REKHA KHARE MD RADIOLOGY
  • 2.  A young man was referred from neurology OPD for MRI cervical spine with the complaints of numbness of left arm, for last six months
  • 3.  Neurological exam. revealed normal higher mental and cranial nerve function  No motor power loss is noticed in left arm, grip was normal  X-ray cervical spine - AP and Lateral view shows nothing significant  Routine Lab examination was found with in normal limit
  • 4.  All standard sequences were taken  Non contrast MRI revealed an relatively well defined cystic nodular intramedullary hypo intense lesion on T1W1 sequence with hyper intense nidus lesion in the center at C2-3 level  Lesion gets hyper intense on T2 W1 sequence with mild hyper density in surrounding area
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  • 10.  Contrast MRI shows: A Ring enhanced lesion with central enhanced nidus and moderate perilesional oedma  Minimal focal syrinx at the level of lesion
  • 11.  Ring enhanced lesion: commonest Tuberculoma and Neurocysticercosis  Other Intramedullary cystic lesion: infection/ abscess, arachnoid cyst,ependymal cyst, neurentric cyst, sarcoidosis,neoplasm
  • 12.  Our case was straight forward case of Intramedullary Cysticercosis – Ring enhanced lesion with pin point dot calcification in the center and oedma in surrounding tissue ** focal syrinx could be the possible reason of the only symptom of Numbness
  • 13.  Cysticercosis is a parasitic disease caused by larval stage of Taenia solium  Cysticercosis in human is first described in 1550 by Pranoli  Cysticercosis is endemic in Indian subcontinent
  • 14.  Commonly cysticercosis occurs due to either ingestion of contaminated vegetables, eaten raw or oral-faecal route  Disease is not restricted to the pork eater who usually harbour the adult parasite
  • 15.  Cysticercosis CNS is common in poor developing region esp. in pediatric age group  Incidence of neurocysticercosis is about 4% of the general population  Isolated Spinal intramedullary cysticercosis is quite rare compared to spinal subarachnoid cysticercosis
  • 16.  It has been described very little. The proposed mechanism of spread is hematogenous dissemination  As thoracic cord receives maximum blood so it is most commonly affected
  • 17.  Most Possible pathogenesis through ventriculo-ependymal spread by migration of larva from ventricle along CSF down to spinal subarachnoid space  Majority of cysticerci can not pass through the subarachnoid space at the cervical level due to its size and physiological sieve
  • 18.  Cyst may increase with in cord and so produce symptoms like that of small syrinx  Toxic effects include local inflammation secondary to leakage of parasitic metabolic by product with in the cyst fluid  Vascular compromise secondarily results in cord ischemia and myelomalacia
  • 19. Tuberculoma  Irregular in shape  Solid  Ring enhanced lesion more than 2cm  Severe perilesional oedma with mass effect/ focal neurological deficit  TB else where Neurocysticercosis  Round  Cystic  Ring enhanced lesion less than 2cm with visible scolex/nidus.. Target lesion  Perilesional oedma not enough to produce mass effect
  • 20.  Intramedullary cysticercosis represents a diagnostic challenge  TARGET LESION: Ring enhanced small lesion with pin point dense center/scolex and usually with mild perilesional oedma is quite characteristic  it should be strongly considered in low socio- economic poor developing area
  • 21.  Major cause of adult onset Epilepsy in the developing world  CNS and eye involvement is termed as Neurocysticercosis  Predilection for migration to eyes, CNS and striated muscle probably due to increased glycogen and glucose content of these tissue  Radiological staging: visible cyst with scolex degenerating cyst calcified cyst
  • 22.  Bin Qi,Pengfei Ge, Hongfa Yang, Chunhua Bi and YipingLi. Spinal Intramedullary Cysticercosis: A case Report and Literature Review: Int J Med Sci 2011;8(5)420-423  Kumar S, Handa A, Chavda S. et al. Intramedullary cysticercosis. J Clin Neurosci.2010;17(4): 522-3[pub med]  Lt Col PK Sahoo. Spinal Intramedullary Cysticercosis.MJAFI2000,56:240-241  Mathuria SN, Khosla VK, Vasistha RK et al Intramedullary cysticercosis;MRI diagnosis.Neurol India.2001;49(10: 71-4[pub med]
  • 23.  Shubhangi V Agale, Shweta Bhavsar and Vidhya Manohar: Isolated intramedullary spinal cord cysticercosis. Asian J Neurosurg.2012 Apr- Jun;7(2):90-92  Singh p, Sahai K. Intramedullary cysticercosis. NeurolIndia 2004:52:264-5(pub Med)  Taveras JM,Wood Eh. Diagnostic neuro radiology. 2nd ed.Baltimore The Williams and Wilkins company 1977:1162
  • 24. HAVE A NICE DAY