This document summarizes the establishment of DONASUR, a registry for organ donation and transplantation within the Mercosur trade bloc. It discusses the creation of an intergovernmental commission to promote policies to harmonize legal frameworks around organ donation. The commission will develop common strategies for donation and transplantation in member countries, including a regional registry and coding system to facilitate organ sharing. An executive committee was formed to manage the new DONASUR registry and oversee the initial data collection and official launch between member states of Mercosur and associated countries.