The document analyzes and compares the legal frameworks governing organ and tissue transplantation in Latin American countries. Most countries have laws addressing consent to donation, determining death, living donation, and foreign patients. Consent policies range from familial consent to presumed consent. Death determination policies specify medical diagnostic criteria or rely on medical protocols. Living donation policies allow related or unrelated donors, with some establishing donor preferences. Ecuador uniquely mandates inclusion of foreign patients on waiting lists. Harmonization efforts aim to develop coherent legal frameworks and cooperation agreements across countries.