This document discusses induction of labor and augmentation of labor. Induction of labor is artificially initiating uterine contractions before their spontaneous onset, while augmentation is attempting to assist or accelerate labor that has begun normally. Common indications for induction include preeclampsia, PROM, post-term pregnancy, and fetal issues like IUFD or severe IUGR. Contraindications include severe CPD, major placenta previa, and active genital herpes. Methods of induction include cervical ripening using prostaglandins or dilators followed by oxytocin or amniotomy to induce contractions. Oxytocin administration begins at 1 mU/min and is increased every 30 minutes until effective contractions occur.
Labour induction
Induction of labour
Guidelines on induction of labour
Guidelines on labour induction
induction of labour is not risk free
prostaglandins for induction of labour
Bishop score
Cervical ripening techniques
mechanical and pharmacological induction of labour
Post dates induction
options for cervical ripening
oral vs. vaginal misoprostol
advantages diadvantages and techniques for induction of labour
gynecology & obstetrics
Labour induction methods
review of guidelines for labour induction
Labour induction
Induction of labour
Guidelines on induction of labour
Guidelines on labour induction
induction of labour is not risk free
prostaglandins for induction of labour
Bishop score
Cervical ripening techniques
mechanical and pharmacological induction of labour
Post dates induction
options for cervical ripening
oral vs. vaginal misoprostol
advantages diadvantages and techniques for induction of labour
gynecology & obstetrics
Labour induction methods
review of guidelines for labour induction
Prolonged labor is the inability of a woman to proceed with childbirth upon going into labor. Prolonged labor typically lasts over 20 hours for first time mothers, and over 14 hours for women that have already had children.
Hope it helps.. This presentation describes about labour induction, its types, methods, management and responsibilities. also the procedure of performing the methods. pictures as per need attached for the reference. like and comment if any suggestion.
Prolonged labor is the inability of a woman to proceed with childbirth upon going into labor. Prolonged labor typically lasts over 20 hours for first time mothers, and over 14 hours for women that have already had children.
Hope it helps.. This presentation describes about labour induction, its types, methods, management and responsibilities. also the procedure of performing the methods. pictures as per need attached for the reference. like and comment if any suggestion.
OBSTETRICS AND GYNAECOLOGICAL NURSING- HIGH RISK PREGNANCY ABORTION.pptxmagie12
The students will be able to
*define abortion
*Identify the difference between various types of abortion
*Perform medical induction for abortion
*Describe various surgical techniques used for abortion
*Detect the consequences that occur by abortion and provide appropriate care
Abortion or pregnancy loss is accounts to spontaneous events or through legal termination.
The first large scale study on abortions and unintended pregnancies conducted by The Lancet in 2017 said one in three of the 48.1 million pregnancies in India end in an abortion with 15.6 million taking place in 2015.
*Definition
*Types of abortion- Spontaneous, Induced, Complete abortion, Incomplete abortion, Missed abortion, Recurrent abortion, Induced abortion
*Risk factors,
*etiology, mechanism,
* clinical manifestations of each type
*Management – medical & surgical
Nursing management
Abortion is the expulsion or extraction from its mother of an embryo or fetus weighing 500 gm or less when it is not capable of independent survival
-WHO
The 500gm of fetal development is attained
approximately at 22 weeks(154 days of gestation).
The expelled embryo or fetus is called abortus
Abortion is the cause for bleeding in early pregnancy.
Abortion occurring without medical or mechanical means to empty the uterus is referred to as spontaneous.
Another widely used term is miscarriage.
10-20% of cases of all clinical pregnancies end in miscarriage.
About 75%miscarriages –before 16th week
About 80% occur –before 12th week of pregnancy.
Increases with parity
Increased maternal and paternal age
The frequency of abortion increases from 12% in women younger than 20 years to 26% in those older than 40 years
Women conceiving within 3 months following a term birth, have a higher incidence of abortion
Anembryonic Gestational sac
- Positive HCG test as placenta secretes HCG and stops later
Presents in first few weeks of pregnancy
Removal through medical or surgical induction
Uncommon causes of abortion in human
Listeria monocytogenes
Clamydia trachomatis
Mycoplasma hominis
Ureaplasma urealyticum
Toxoplasma gondii
Diabetes mellitus
Celiac sprue
Cause both male and female infertility and recurrent abortions
ENDOCRINE ABNORMALITIES
Hypothyroidism
Thyroid autoantibodies → incidence of abortion is high
Diabetes mellitus
Poor glucose control → incidence of abortion increased
Progesterone deficiency
Luteal phase defect
Insufficient progesterone secretion by the corpus luteum or placenta
DRUG USE AND ENVIRONMENTAL FACTORS
Recurrent pregnancy loss patients : 15%
Antiphospholipid antibody : most significant
LCA (lupus anticoagulant), ACA (anticardiolipin Ab)
ALLOIMMUNE FACTORS
- Inherited thrombophilia
Uterine synechiae (Asherman syndrome)
Partial or complete obliteration of the uterine cavity by adherence of uterine wall
The retention power of the cervix(Internal os) may be impaired functionally and or anatomically in an incompetent cervix
Etiology
Previous trauma during pregnancy
This interesting ppt outlines the pharmacological measures in obstetrics clinically...It'll be useful for the clinicians and beginners in obstetrics...
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
MANAGEMENT OF ATRIOVENTRICULAR CONDUCTION BLOCK.pdfJim Jacob Roy
Cardiac conduction defects can occur due to various causes.
Atrioventricular conduction blocks ( AV blocks ) are classified into 3 types.
This document describes the acute management of AV block.
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
- ARTIFICIAL INTELLIGENCE AND ETHICS
- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
These lecture slides, by Dr Sidra Arshad, offer a quick overview of physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar leads (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
2. Induction of labour
Augmentation of
labour
Elective induction of
labour
Artificially initiating uterine contraction prior
to their spontaneous onset.
Attempt to assists or accelerate labour that
have been already begun normally.
Initiation of labour at term pregnancy without
any acceptable medical or obstetric indications
4. Severe degree CPD
Major degree placenta previa
Transverse lie or breech presentation
Previous classical CS, Myomectomy
Contracted pelvis
Grand multipara or old primigravida
Active genital herpes
Hypersensitivity to the inducing
agent
CONTRAINDICATIONS
5. Failure leading to CS
Uterine hyperstimulation
Fetal distress,death
Rupture uterus
Intrauterine infection,sepsis
Iatrogenic delivery of preterm infant
Precipitate/dysfunctional labour
Inc. risk of operative vaginal delivery
Inc. risk of birth trauma
Inc. risk of PPH
Complications
6. Decision taken to induce labour
Cervical status Bishop score
Cervix ripes Cervix doesn’t ripe
Induce labour
Ripe cervix then induce
labour
assessme
nt
7.
8. Methods of cervical ripening
natural mechanical pharmacological
• Walking
• Having sex
• Nipple
stimulation
• Enema
• Acupressu
re
• Hygroscopi
c dilators
• Transcervic
al catheter
• Stripping
the
membranes
• Prostaglandin
E2:
(dinoproston
e)
• Prostaglandin
E1
13. • Oxytocin infusion should be given in the smallest
possible volume, commencing at a rate of 1
mU/min
• Usually start by 5 units in 500mls of normal
saline or Ringer’s solution [10 mU/ml]
• Increase infusion rate (by doubling drops / min)
at intervals of 30 min, until there are 3-5 good
contractions every 10 min each lasting 45-60 sec.
[1 ml=15-drops]
• If 60 drop/min rate is reached with no efficient
contractions replace the infusion with 10 units
oxytocin in 500 mls
• Total dose of oxytocin should not exceed 5 units
Oxytocin Regimen: