Presentation on (semantic) nanopublications (specifically in biomedicine) given at iExpo in Paris, 10 June 2010. Partially in French (but mostly with English translation).
(in Apple Keynote 09)
Science publications used to have the joint function of keeping the 'Minutes of Science' as well as transferring knowledge. The sheer amounts of material published (2 new articles in PubMed every minute of every day) make comprehensive knowledge transfer via reading of articles virtually impossible. When the literature is open, though, much of the essential knowledge it contains can be distilled and the big picture obtained without having to read all the articles, so that reading can then be reserved for those key articles that give insight in the reasoning and argumentation that leads to consensus. The result is a much more efficient knowledge transfer that doesn't have to compromise on comprehensiveness.
Reshaping the research library.LIBER's involvement in The European LibraryLIBER Europe
Izaskun Lacunza, LIBER Executive Director, presents LIBER's strategy and LIBER's involvement in The European Library at the Research Library United Kingdgom (RLUK) workshop for members
Science publications used to have the joint function of keeping the 'Minutes of Science' as well as transferring knowledge. The sheer amounts of material published (2 new articles in PubMed every minute of every day) make comprehensive knowledge transfer via reading of articles virtually impossible. When the literature is open, though, much of the essential knowledge it contains can be distilled and the big picture obtained without having to read all the articles, so that reading can then be reserved for those key articles that give insight in the reasoning and argumentation that leads to consensus. The result is a much more efficient knowledge transfer that doesn't have to compromise on comprehensiveness.
Reshaping the research library.LIBER's involvement in The European LibraryLIBER Europe
Izaskun Lacunza, LIBER Executive Director, presents LIBER's strategy and LIBER's involvement in The European Library at the Research Library United Kingdgom (RLUK) workshop for members
"Towards a Science of Reproducible Science?" DPRMA Workshop talk at JCDL 2013, Indianapolis, 25th July 2013. Workshop website is http://dprma.oerc.ox.ac.uk/
Paper is
David De Roure. 2013. Towards computational research objects. In Proceedings of the 1st International Workshop on Digital Preservation of Research Methods and Artefacts (DPRMA '13). ACM, New York, NY, USA, 16-19. DOI=10.1145/2499583.2499590 http://doi.acm.org/10.1145/2499583.2499590
How SADI & SHARE help restore the Scientific Method to in silico scienceMark Wilkinson
This is my presentation to the Bio Open Source Convention (BOSC) in Boston, July 2010. I start with a brief status-update on the BioMoby project and then launch into a series of demonstrations of it's successor - SADI + SHARE. Rather than discussing how SADI/SHARE work, I focus the discussion on what role I think these technologies can play in bringing the traditional "scientific method" back into in silico biology.
Create Linked Open Data (LOD) Microthesauri using Art & Architecture Thesaurus (AAT) LOD. View and manage options by a non-techy person. Everyone can use, create,
derive from, & map to AAT microthesauri and make the digital collection become LOD-ready dataset.
Final version of my presentation to BioIT World Congress, Boston MA, April 22, 2010.
Describes how we're using the SADI Semantic Web Service framework to begin personalizing medical research.
Franz sterner tdwg 2016 new power balance needed for trustworthy biodiversity...taxonbytes
View a video recording here: https://vimeo.com/195024485
Franz & Sterner @ #TDWG16 - "A new power balance is needed for trustworthy biodiversity data". Talk # 1134, Friday, December 09, 2016, 11:30 am. Session Contributed Papers 05: Data Gaps, Trust, Knowledge Acquisition. See https://mbgserv18.mobot.org/ocs/index.php/tdwg/tdwg2016/schedConf/program
Slides based on a workshop held at SEMANTiCS 2018 in Vienna. Introduces a methodology for knowledge graph management based on Semantic Web standards, ranging from taxonomies over ontologies, mappings, graph and entity linking. Further topics covered: Semantic AI and machine learning, text mining, and semantic search.
YesWorkflow: Retrospective Provenance Without a Runtime Provenance RecorderBertram Ludäscher
The YesWorkflow (YW) toolkit aims to provide users of script- ing languages such as Python, Perl, and R with many of the ben- efits of scientific workflow automation. YW requires neither the use of a workflow engine nor the overhead of adapting or instru- menting code to run in such a system. Instead, YW enables sci- entists to annotate their scripts with special comments that reveal the main computational blocks and dataflow dependencies other- wise implicit in scripts. YW tools extract and analyze these com- ments, represent scripts in terms of entities based on a typical scien- tific workflow model, and provide graphical workflow views (i.e., prospective provenance) of scripts. In this paper, we present a new extension of YW for inferring retrospective provenance from script executions without relying on a runtime provenance recorder. Instead we exploit the common practice of scientists to embed im- portant pieces of provenance in directory structures and file names. For such “provenance-friendly” data organizations, we offer a new annotation mechanism based on URI templates. YW uses these to link conceptual-level prospective provenance with data files created at runtime, resulting in a powerful, integrated model of prospective and retrospective provenance. We present scientifically meaningful retrospective provenance queries for investigating an execution of a data acquisition workflow implemented as a Python script, and show how these queries can be evaluated using the YW toolkit.
Interest in Deep Learning has been growing in the past few years. With advances in software and hardware technologies, Neural Networks are making a resurgence. With interest in AI based applications growing, and companies like IBM, Google, Microsoft, NVidia investing heavily in computing and software applications, it is time to understand Deep Learning better!
In this workshop, we will discuss the basics of Neural Networks and discuss how Deep Learning Neural networks are different from conventional Neural Network architectures. We will review a bit of mathematics that goes into building neural networks and understand the role of GPUs in Deep Learning. We will also get an introduction to Autoencoders, Convolutional Neural Networks, Recurrent Neural Networks and understand the state-of-the-art in hardware and software architectures. Functional Demos will be presented in Keras, a popular Python package with a backend in Theano and Tensorflow.
A document-inspired way for tracking changes of RDF data - The case of the Op...University of Bologna
There are several distinct ways to represent data drift in the Linked Open Data world. In this presentation we introduce an approach for tracking data changes that has been used in the context of the OpenCitations Project. Such approach has been inspired by existing works on change tracking mechanisms in documents created through word-processors such as Microsoft Word and OpenOffice Writer.
Acute scrotum is a general term referring to an emergency condition affecting the contents or the wall of the scrotum.
There are a number of conditions that present acutely, predominantly with pain and/or swelling
A careful and detailed history and examination, and in some cases, investigations allow differentiation between these diagnoses. A prompt diagnosis is essential as the patient may require urgent surgical intervention
Testicular torsion refers to twisting of the spermatic cord, causing ischaemia of the testicle.
Testicular torsion results from inadequate fixation of the testis to the tunica vaginalis producing ischemia from reduced arterial inflow and venous outflow obstruction.
The prevalence of testicular torsion in adult patients hospitalized with acute scrotal pain is approximately 25 to 50 percent
"Towards a Science of Reproducible Science?" DPRMA Workshop talk at JCDL 2013, Indianapolis, 25th July 2013. Workshop website is http://dprma.oerc.ox.ac.uk/
Paper is
David De Roure. 2013. Towards computational research objects. In Proceedings of the 1st International Workshop on Digital Preservation of Research Methods and Artefacts (DPRMA '13). ACM, New York, NY, USA, 16-19. DOI=10.1145/2499583.2499590 http://doi.acm.org/10.1145/2499583.2499590
How SADI & SHARE help restore the Scientific Method to in silico scienceMark Wilkinson
This is my presentation to the Bio Open Source Convention (BOSC) in Boston, July 2010. I start with a brief status-update on the BioMoby project and then launch into a series of demonstrations of it's successor - SADI + SHARE. Rather than discussing how SADI/SHARE work, I focus the discussion on what role I think these technologies can play in bringing the traditional "scientific method" back into in silico biology.
Create Linked Open Data (LOD) Microthesauri using Art & Architecture Thesaurus (AAT) LOD. View and manage options by a non-techy person. Everyone can use, create,
derive from, & map to AAT microthesauri and make the digital collection become LOD-ready dataset.
Final version of my presentation to BioIT World Congress, Boston MA, April 22, 2010.
Describes how we're using the SADI Semantic Web Service framework to begin personalizing medical research.
Franz sterner tdwg 2016 new power balance needed for trustworthy biodiversity...taxonbytes
View a video recording here: https://vimeo.com/195024485
Franz & Sterner @ #TDWG16 - "A new power balance is needed for trustworthy biodiversity data". Talk # 1134, Friday, December 09, 2016, 11:30 am. Session Contributed Papers 05: Data Gaps, Trust, Knowledge Acquisition. See https://mbgserv18.mobot.org/ocs/index.php/tdwg/tdwg2016/schedConf/program
Slides based on a workshop held at SEMANTiCS 2018 in Vienna. Introduces a methodology for knowledge graph management based on Semantic Web standards, ranging from taxonomies over ontologies, mappings, graph and entity linking. Further topics covered: Semantic AI and machine learning, text mining, and semantic search.
YesWorkflow: Retrospective Provenance Without a Runtime Provenance RecorderBertram Ludäscher
The YesWorkflow (YW) toolkit aims to provide users of script- ing languages such as Python, Perl, and R with many of the ben- efits of scientific workflow automation. YW requires neither the use of a workflow engine nor the overhead of adapting or instru- menting code to run in such a system. Instead, YW enables sci- entists to annotate their scripts with special comments that reveal the main computational blocks and dataflow dependencies other- wise implicit in scripts. YW tools extract and analyze these com- ments, represent scripts in terms of entities based on a typical scien- tific workflow model, and provide graphical workflow views (i.e., prospective provenance) of scripts. In this paper, we present a new extension of YW for inferring retrospective provenance from script executions without relying on a runtime provenance recorder. Instead we exploit the common practice of scientists to embed im- portant pieces of provenance in directory structures and file names. For such “provenance-friendly” data organizations, we offer a new annotation mechanism based on URI templates. YW uses these to link conceptual-level prospective provenance with data files created at runtime, resulting in a powerful, integrated model of prospective and retrospective provenance. We present scientifically meaningful retrospective provenance queries for investigating an execution of a data acquisition workflow implemented as a Python script, and show how these queries can be evaluated using the YW toolkit.
Interest in Deep Learning has been growing in the past few years. With advances in software and hardware technologies, Neural Networks are making a resurgence. With interest in AI based applications growing, and companies like IBM, Google, Microsoft, NVidia investing heavily in computing and software applications, it is time to understand Deep Learning better!
In this workshop, we will discuss the basics of Neural Networks and discuss how Deep Learning Neural networks are different from conventional Neural Network architectures. We will review a bit of mathematics that goes into building neural networks and understand the role of GPUs in Deep Learning. We will also get an introduction to Autoencoders, Convolutional Neural Networks, Recurrent Neural Networks and understand the state-of-the-art in hardware and software architectures. Functional Demos will be presented in Keras, a popular Python package with a backend in Theano and Tensorflow.
A document-inspired way for tracking changes of RDF data - The case of the Op...University of Bologna
There are several distinct ways to represent data drift in the Linked Open Data world. In this presentation we introduce an approach for tracking data changes that has been used in the context of the OpenCitations Project. Such approach has been inspired by existing works on change tracking mechanisms in documents created through word-processors such as Microsoft Word and OpenOffice Writer.
Acute scrotum is a general term referring to an emergency condition affecting the contents or the wall of the scrotum.
There are a number of conditions that present acutely, predominantly with pain and/or swelling
A careful and detailed history and examination, and in some cases, investigations allow differentiation between these diagnoses. A prompt diagnosis is essential as the patient may require urgent surgical intervention
Testicular torsion refers to twisting of the spermatic cord, causing ischaemia of the testicle.
Testicular torsion results from inadequate fixation of the testis to the tunica vaginalis producing ischemia from reduced arterial inflow and venous outflow obstruction.
The prevalence of testicular torsion in adult patients hospitalized with acute scrotal pain is approximately 25 to 50 percent
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
Couples presenting to the infertility clinic- Do they really have infertility...Sujoy Dasgupta
Dr Sujoy Dasgupta presented the study on "Couples presenting to the infertility clinic- Do they really have infertility? – The unexplored stories of non-consummation" in the 13th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE 2024) at Manila on 24 May, 2024.
Explore natural remedies for syphilis treatment in Singapore. Discover alternative therapies, herbal remedies, and lifestyle changes that may complement conventional treatments. Learn about holistic approaches to managing syphilis symptoms and supporting overall health.
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
These lecture slides, by Dr Sidra Arshad, offer a quick overview of physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar leads (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
New Drug Discovery and Development .....NEHA GUPTA
The "New Drug Discovery and Development" process involves the identification, design, testing, and manufacturing of novel pharmaceutical compounds with the aim of introducing new and improved treatments for various medical conditions. This comprehensive endeavor encompasses various stages, including target identification, preclinical studies, clinical trials, regulatory approval, and post-market surveillance. It involves multidisciplinary collaboration among scientists, researchers, clinicians, regulatory experts, and pharmaceutical companies to bring innovative therapies to market and address unmet medical needs.
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
NVBDCP.pptx Nation vector borne disease control programSapna Thakur
NVBDCP was launched in 2003-2004 . Vector-Borne Disease: Disease that results from an infection transmitted to humans and other animals by blood-feeding arthropods, such as mosquitoes, ticks, and fleas. Examples of vector-borne diseases include Dengue fever, West Nile Virus, Lyme disease, and malaria.
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
3. laisser un trace – the record*
“le compte-rendu de la science” – “keeping the minutes of science”
1 of S
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ord
*image inspirée par Geoffrey Bilder de chez CrossRef
4. laisser un trace – the record*
“le compte-rendu de la science” – “keeping the minutes of science”
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Th
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e
e c
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d
*image inspirée par Geoffrey Bilder de chez CrossRef
5. leur crédit dans un “égo-système”:
une économie de la reconnaissance*
2
*”économie de la reconnaissance” néologisme créé par Geoffrey Bilder de chez CrossRef
6. leur crédit dans un “égo-système”:
une économie de la reconnaissance*
2
*”économie de la reconnaissance” néologisme créé par Geoffrey Bilder de chez CrossRef
7. 1+2=
l’interface avec l’officialité *
the interface with officialdom *
*néologisme de Salvatore Mele du CERN
25. Molecular Biology Laboratory in Heidelberg, Germany,
and won Elsevier’s Grand Challenge 2009 competition
for new tools that improve the communication and use
of scientific information.
Reflect automatically recognizes and highlights the
names of genes, proteins and small molecules in the Cell
articles. Users clicking on a highlighted term will see a pop-
PubMed: un nouvel
up box containing information related to that term, such as
sequence data and molecular structures, along with links to
article toutes les 36
the sources of the data. Reflect obtains this information from
its dictionary of millions of proteins and small molecules.
secondes
Such ‘entity recognition’ can be done fairly accurately
by many mining tools today. But other tools take on the
tougher challenge of recognizing relationships between the
entities. Researchers from Leiden University and Erasmus
University in Rotterdam, both in the Netherlands, have
developed software called Peregrine, and used it to pre-
dict an undocumented interaction between two proteins:
ACKnowledge
26.
27.
28. Avoir une vision d’ensemble
pour commencer?
Create an overview first?
38. Les Nanopublications: des Assertions ayant des Attributs
Exemples d’attributs:
assertedBy - indique quelle est l’entité à l’origine (qui l’a créée) de l’assertion
curatedBy - indique qu’une entité donnée a géré l’assertion
isPeerReviewed - indique que cette assertion est passée par un arbitrage entre pairs
(peer review)
isEvidencedBy - indique qu’une autre assertion, Y, doit être tenue comme preuve de
l’assertion X en question
createdOn - indique la date/heure de création de l’assertion
hasAuthor - indique qui affirme être auteur de l’assertion
isApprovedBy - indique qui a approuvé l’assertion
isDeprecatedBy - indique que l’assertion n’est plus utilisée par l’entité en question
ACKnowledge
78. Les nanopublications peuvent aussi servir à déduire
Nanopublications can also be used to reason
protein X
protein A
ACKnowledge
79. Citation: van Haagen HHHBM, 't Hoen PAC, Botelho Bovo A, de Morrée A, van Mulligen EM, et al.
(2009) Novel Protein-Protein Interactions Inferred from Literature Context. PLoS ONE 4(11): e7894.
doi:10.1371/journal.pone.0007894
