The document summarizes key aspects of the human eye and vision. It describes the structure of the eye, including the cornea, iris, pupil, lens, retina, and other parts. It explains how the iris controls the size of the pupil to regulate the amount of light entering the eye. It also discusses refractive errors like myopia and hyperopia, and how lenses are used to correct vision. Prisms and dispersion of light are described. Atmospheric effects like refraction, twinkling of stars, and why the sky appears blue are summarized.
The presentation includes detailed content including Real-World Examples.... It also includes You-Tube Links to access amazing activities based videos, which makes your concepts more clear and easier....
This is a chapter on electricity for the students of gr 10. this will make the chapter 100% easier and it is tested. for reviews browse www.anupamravi17.wix.com/outlawairbands. this is the official website of the outlaws gaming society. you will also get important gaming updates if you are an addicted gamer LOL Hope U Enjoy!!! if any doubts on this chapter just below in the comments section. Peace Stay fresh.
Magnetic Effects of Electric Current 10th PhysicsSHIVAM RANJAN
The magnetic effect of electric current is known as electromagnetic effect. It is observed that when a compass is brought near a current carrying conductor the needle of compass gets deflected because of flow of electricity. This shows that electric current produces a magnetic effect.
In this ppt, i tried to give my best so that any one who wants to find the same gains some knowledge or material from it.
For more updates contact me at 7807907761/myrules663@gmail.com
The presentation includes detailed content including Real-World Examples.... It also includes You-Tube Links to access amazing activities based videos, which makes your concepts more clear and easier....
This is a chapter on electricity for the students of gr 10. this will make the chapter 100% easier and it is tested. for reviews browse www.anupamravi17.wix.com/outlawairbands. this is the official website of the outlaws gaming society. you will also get important gaming updates if you are an addicted gamer LOL Hope U Enjoy!!! if any doubts on this chapter just below in the comments section. Peace Stay fresh.
Magnetic Effects of Electric Current 10th PhysicsSHIVAM RANJAN
The magnetic effect of electric current is known as electromagnetic effect. It is observed that when a compass is brought near a current carrying conductor the needle of compass gets deflected because of flow of electricity. This shows that electric current produces a magnetic effect.
In this ppt, i tried to give my best so that any one who wants to find the same gains some knowledge or material from it.
For more updates contact me at 7807907761/myrules663@gmail.com
This PPT is based on Physics on Chapter Motion. In this you will find every thing of that chapter with great images. in this PPT their are many animation and images .
thank you
This Presentation is especially for the grade 10 as it is informaive and can be used for the CBSE syllabus of india ( of course ). hope this helps you alot and if any problems please let me know from the comments section below.................peace out......... and message me at bavitharavi@hotmail.com. this is also the chpter 9 of the cbse gr 10 science book biology.
The following power point discusses about the Chemical Effects of Electric Current. In this, we study about how electricity is conduced in liquids, electrolysis and the uses and applications of it
Physics ( human eye and the colourful world).Nikhil Dahiya
ppt on human eye and its structure. shows different parts of the eye . helps the student to learn about the eye more breifly.it is a science ppt which will be helpfull . teachers can also take it in the us for letting the students understand better .
This PPT is based on Physics on Chapter Motion. In this you will find every thing of that chapter with great images. in this PPT their are many animation and images .
thank you
This Presentation is especially for the grade 10 as it is informaive and can be used for the CBSE syllabus of india ( of course ). hope this helps you alot and if any problems please let me know from the comments section below.................peace out......... and message me at bavitharavi@hotmail.com. this is also the chpter 9 of the cbse gr 10 science book biology.
The following power point discusses about the Chemical Effects of Electric Current. In this, we study about how electricity is conduced in liquids, electrolysis and the uses and applications of it
Physics ( human eye and the colourful world).Nikhil Dahiya
ppt on human eye and its structure. shows different parts of the eye . helps the student to learn about the eye more breifly.it is a science ppt which will be helpfull . teachers can also take it in the us for letting the students understand better .
the current topic contain information about anatomy of human eye and defect in vision and their corrections the p.p.t. also explain dispersion and scattering of light this p.p.t.is very useful f for secondary classes students
Human Eye and Colorful World. Chapter 11 grade 10thMurari Parashar
Chapter 11 Human Eye and Colorful World. Human eye is the optical instrument used which enables us to see.
We will study various natural optical phenomenon like Rainbow formation, twinkling of star, blue and red color of sky etc.
In the realm of biology, the human eye is a marvel of nature's engineering, allowing us to perceive the world around us with clarity and detail. It is not only a sensory organ but also a gateway to understanding the physics of light and color. Class 10 Science introduces students to the intricacies of the human eye and its interaction with light, delving into topics such as refraction, dispersion, and the perception of color. In this detailed study guide, we will explore these concepts comprehensively to aid students in understanding this fascinating aspect of biology and physics.
For more information, visit-www.vavaclasses.com
The human eye is one of the most valuable and sensitive sense organs in the human body. It enables us to see the wonderful world and colours around us.
Structure of eye:
The human eye has the following main parts:
Cornea: It is the transparent spherical membrane covering the front of the eye. Light enters the eye through this membrane.
Crystalline lens: The eyes lens is a convex lens made of a transparent, soft and flexible material like a jelly made of proteins.
Iris: It is a dark muscular diaphragm between the cornea and the lens. It controls the size of the pupil. It is the colour of the iris that we call as the colour of the eye.
Pupil: It is a small hole between the iris through which light enters the eye. In dim light, it opens up completely due to expansion of iris muscles, but in bright light it becomes very small due to contraction of iris muscles.
(May 29th, 2024) Advancements in Intravital Microscopy- Insights for Preclini...Scintica Instrumentation
Intravital microscopy (IVM) is a powerful tool utilized to study cellular behavior over time and space in vivo. Much of our understanding of cell biology has been accomplished using various in vitro and ex vivo methods; however, these studies do not necessarily reflect the natural dynamics of biological processes. Unlike traditional cell culture or fixed tissue imaging, IVM allows for the ultra-fast high-resolution imaging of cellular processes over time and space and were studied in its natural environment. Real-time visualization of biological processes in the context of an intact organism helps maintain physiological relevance and provide insights into the progression of disease, response to treatments or developmental processes.
In this webinar we give an overview of advanced applications of the IVM system in preclinical research. IVIM technology is a provider of all-in-one intravital microscopy systems and solutions optimized for in vivo imaging of live animal models at sub-micron resolution. The system’s unique features and user-friendly software enables researchers to probe fast dynamic biological processes such as immune cell tracking, cell-cell interaction as well as vascularization and tumor metastasis with exceptional detail. This webinar will also give an overview of IVM being utilized in drug development, offering a view into the intricate interaction between drugs/nanoparticles and tissues in vivo and allows for the evaluation of therapeutic intervention in a variety of tissues and organs. This interdisciplinary collaboration continues to drive the advancements of novel therapeutic strategies.
Multi-source connectivity as the driver of solar wind variability in the heli...Sérgio Sacani
The ambient solar wind that flls the heliosphere originates from multiple
sources in the solar corona and is highly structured. It is often described
as high-speed, relatively homogeneous, plasma streams from coronal
holes and slow-speed, highly variable, streams whose source regions are
under debate. A key goal of ESA/NASA’s Solar Orbiter mission is to identify
solar wind sources and understand what drives the complexity seen in the
heliosphere. By combining magnetic feld modelling and spectroscopic
techniques with high-resolution observations and measurements, we show
that the solar wind variability detected in situ by Solar Orbiter in March
2022 is driven by spatio-temporal changes in the magnetic connectivity to
multiple sources in the solar atmosphere. The magnetic feld footpoints
connected to the spacecraft moved from the boundaries of a coronal hole
to one active region (12961) and then across to another region (12957). This
is refected in the in situ measurements, which show the transition from fast
to highly Alfvénic then to slow solar wind that is disrupted by the arrival of
a coronal mass ejection. Our results describe solar wind variability at 0.5 au
but are applicable to near-Earth observatories.
Observation of Io’s Resurfacing via Plume Deposition Using Ground-based Adapt...Sérgio Sacani
Since volcanic activity was first discovered on Io from Voyager images in 1979, changes
on Io’s surface have been monitored from both spacecraft and ground-based telescopes.
Here, we present the highest spatial resolution images of Io ever obtained from a groundbased telescope. These images, acquired by the SHARK-VIS instrument on the Large
Binocular Telescope, show evidence of a major resurfacing event on Io’s trailing hemisphere. When compared to the most recent spacecraft images, the SHARK-VIS images
show that a plume deposit from a powerful eruption at Pillan Patera has covered part
of the long-lived Pele plume deposit. Although this type of resurfacing event may be common on Io, few have been detected due to the rarity of spacecraft visits and the previously low spatial resolution available from Earth-based telescopes. The SHARK-VIS instrument ushers in a new era of high resolution imaging of Io’s surface using adaptive
optics at visible wavelengths.
Introduction:
RNA interference (RNAi) or Post-Transcriptional Gene Silencing (PTGS) is an important biological process for modulating eukaryotic gene expression.
It is highly conserved process of posttranscriptional gene silencing by which double stranded RNA (dsRNA) causes sequence-specific degradation of mRNA sequences.
dsRNA-induced gene silencing (RNAi) is reported in a wide range of eukaryotes ranging from worms, insects, mammals and plants.
This process mediates resistance to both endogenous parasitic and exogenous pathogenic nucleic acids, and regulates the expression of protein-coding genes.
What are small ncRNAs?
micro RNA (miRNA)
short interfering RNA (siRNA)
Properties of small non-coding RNA:
Involved in silencing mRNA transcripts.
Called “small” because they are usually only about 21-24 nucleotides long.
Synthesized by first cutting up longer precursor sequences (like the 61nt one that Lee discovered).
Silence an mRNA by base pairing with some sequence on the mRNA.
Discovery of siRNA?
The first small RNA:
In 1993 Rosalind Lee (Victor Ambros lab) was studying a non- coding gene in C. elegans, lin-4, that was involved in silencing of another gene, lin-14, at the appropriate time in the
development of the worm C. elegans.
Two small transcripts of lin-4 (22nt and 61nt) were found to be complementary to a sequence in the 3' UTR of lin-14.
Because lin-4 encoded no protein, she deduced that it must be these transcripts that are causing the silencing by RNA-RNA interactions.
Types of RNAi ( non coding RNA)
MiRNA
Length (23-25 nt)
Trans acting
Binds with target MRNA in mismatch
Translation inhibition
Si RNA
Length 21 nt.
Cis acting
Bind with target Mrna in perfect complementary sequence
Piwi-RNA
Length ; 25 to 36 nt.
Expressed in Germ Cells
Regulates trnasposomes activity
MECHANISM OF RNAI:
First the double-stranded RNA teams up with a protein complex named Dicer, which cuts the long RNA into short pieces.
Then another protein complex called RISC (RNA-induced silencing complex) discards one of the two RNA strands.
The RISC-docked, single-stranded RNA then pairs with the homologous mRNA and destroys it.
THE RISC COMPLEX:
RISC is large(>500kD) RNA multi- protein Binding complex which triggers MRNA degradation in response to MRNA
Unwinding of double stranded Si RNA by ATP independent Helicase
Active component of RISC is Ago proteins( ENDONUCLEASE) which cleave target MRNA.
DICER: endonuclease (RNase Family III)
Argonaute: Central Component of the RNA-Induced Silencing Complex (RISC)
One strand of the dsRNA produced by Dicer is retained in the RISC complex in association with Argonaute
ARGONAUTE PROTEIN :
1.PAZ(PIWI/Argonaute/ Zwille)- Recognition of target MRNA
2.PIWI (p-element induced wimpy Testis)- breaks Phosphodiester bond of mRNA.)RNAse H activity.
MiRNA:
The Double-stranded RNAs are naturally produced in eukaryotic cells during development, and they have a key role in regulating gene expression .
Seminar of U.V. Spectroscopy by SAMIR PANDASAMIR PANDA
Spectroscopy is a branch of science dealing the study of interaction of electromagnetic radiation with matter.
Ultraviolet-visible spectroscopy refers to absorption spectroscopy or reflect spectroscopy in the UV-VIS spectral region.
Ultraviolet-visible spectroscopy is an analytical method that can measure the amount of light received by the analyte.
The increased availability of biomedical data, particularly in the public domain, offers the opportunity to better understand human health and to develop effective therapeutics for a wide range of unmet medical needs. However, data scientists remain stymied by the fact that data remain hard to find and to productively reuse because data and their metadata i) are wholly inaccessible, ii) are in non-standard or incompatible representations, iii) do not conform to community standards, and iv) have unclear or highly restricted terms and conditions that preclude legitimate reuse. These limitations require a rethink on data can be made machine and AI-ready - the key motivation behind the FAIR Guiding Principles. Concurrently, while recent efforts have explored the use of deep learning to fuse disparate data into predictive models for a wide range of biomedical applications, these models often fail even when the correct answer is already known, and fail to explain individual predictions in terms that data scientists can appreciate. These limitations suggest that new methods to produce practical artificial intelligence are still needed.
In this talk, I will discuss our work in (1) building an integrative knowledge infrastructure to prepare FAIR and "AI-ready" data and services along with (2) neurosymbolic AI methods to improve the quality of predictions and to generate plausible explanations. Attention is given to standards, platforms, and methods to wrangle knowledge into simple, but effective semantic and latent representations, and to make these available into standards-compliant and discoverable interfaces that can be used in model building, validation, and explanation. Our work, and those of others in the field, creates a baseline for building trustworthy and easy to deploy AI models in biomedicine.
Bio
Dr. Michel Dumontier is the Distinguished Professor of Data Science at Maastricht University, founder and executive director of the Institute of Data Science, and co-founder of the FAIR (Findable, Accessible, Interoperable and Reusable) data principles. His research explores socio-technological approaches for responsible discovery science, which includes collaborative multi-modal knowledge graphs, privacy-preserving distributed data mining, and AI methods for drug discovery and personalized medicine. His work is supported through the Dutch National Research Agenda, the Netherlands Organisation for Scientific Research, Horizon Europe, the European Open Science Cloud, the US National Institutes of Health, and a Marie-Curie Innovative Training Network. He is the editor-in-chief for the journal Data Science and is internationally recognized for his contributions in bioinformatics, biomedical informatics, and semantic technologies including ontologies and linked data.
Slide 1: Title Slide
Extrachromosomal Inheritance
Slide 2: Introduction to Extrachromosomal Inheritance
Definition: Extrachromosomal inheritance refers to the transmission of genetic material that is not found within the nucleus.
Key Components: Involves genes located in mitochondria, chloroplasts, and plasmids.
Slide 3: Mitochondrial Inheritance
Mitochondria: Organelles responsible for energy production.
Mitochondrial DNA (mtDNA): Circular DNA molecule found in mitochondria.
Inheritance Pattern: Maternally inherited, meaning it is passed from mothers to all their offspring.
Diseases: Examples include Leber’s hereditary optic neuropathy (LHON) and mitochondrial myopathy.
Slide 4: Chloroplast Inheritance
Chloroplasts: Organelles responsible for photosynthesis in plants.
Chloroplast DNA (cpDNA): Circular DNA molecule found in chloroplasts.
Inheritance Pattern: Often maternally inherited in most plants, but can vary in some species.
Examples: Variegation in plants, where leaf color patterns are determined by chloroplast DNA.
Slide 5: Plasmid Inheritance
Plasmids: Small, circular DNA molecules found in bacteria and some eukaryotes.
Features: Can carry antibiotic resistance genes and can be transferred between cells through processes like conjugation.
Significance: Important in biotechnology for gene cloning and genetic engineering.
Slide 6: Mechanisms of Extrachromosomal Inheritance
Non-Mendelian Patterns: Do not follow Mendel’s laws of inheritance.
Cytoplasmic Segregation: During cell division, organelles like mitochondria and chloroplasts are randomly distributed to daughter cells.
Heteroplasmy: Presence of more than one type of organellar genome within a cell, leading to variation in expression.
Slide 7: Examples of Extrachromosomal Inheritance
Four O’clock Plant (Mirabilis jalapa): Shows variegated leaves due to different cpDNA in leaf cells.
Petite Mutants in Yeast: Result from mutations in mitochondrial DNA affecting respiration.
Slide 8: Importance of Extrachromosomal Inheritance
Evolution: Provides insight into the evolution of eukaryotic cells.
Medicine: Understanding mitochondrial inheritance helps in diagnosing and treating mitochondrial diseases.
Agriculture: Chloroplast inheritance can be used in plant breeding and genetic modification.
Slide 9: Recent Research and Advances
Gene Editing: Techniques like CRISPR-Cas9 are being used to edit mitochondrial and chloroplast DNA.
Therapies: Development of mitochondrial replacement therapy (MRT) for preventing mitochondrial diseases.
Slide 10: Conclusion
Summary: Extrachromosomal inheritance involves the transmission of genetic material outside the nucleus and plays a crucial role in genetics, medicine, and biotechnology.
Future Directions: Continued research and technological advancements hold promise for new treatments and applications.
Slide 11: Questions and Discussion
Invite Audience: Open the floor for any questions or further discussion on the topic.
2. The human eye is one of the most valuable and sensitive sense organs.
It enables us to see the wonderful world and the colours around us.
It is impossible to identify colours while closing the eyes. Thus, of all the
sense organs, the human eye is the most significant one as it enables us
to see the beautiful, colourful world around us.
The beauty of Human Eye
4. Various parts of the Human Eye
1. Cornea – Light enters the eye through a thin membrane called the cornea. It
forms a transparent bulge on front surface of the eyeball. Most of the refraction for
the light rays entering the eye occurs at the outer surface of cornea.
2. Sclera – It is the outer covering, protective tough white layer called the sclera
3. Eyeball- The eyeball is spherical in shape with a diameter of about 2.3 cm.
4. Aqueous Humour- It is a fluid which fills the space between cornea and the eye
lens.
5. Iris- Iris is a dark muscular diaphragm that controls the size of the pupil.
6. Pupil- Pupil is a small opening in the middle of the iris through which light enters
the eye. The pupil regulates and controls the amount of light entering the eye.
5. 7. Lens - Behind the pupil, there is a transparent and flexible jelly-like structure called a
lens. It is a convex lens. By the action of ciliary muscles, it changes its shape to focus light
on the retina, it becomes thinner to focus distant objects and becomes thicker to focus
nearby objects.
8. Ciliary muscles – The ciliary muscles are capable of modifying the curvature of the lens
and thereby affecting the focal length of the lens.
9. Vitreous Humour - The vitreous humour is a clear fluid which fills the eye between the
lens and the retina. This fluid helps the eye hold its shape, with light being transmitted
through it to the retina.
10. Retina - Retina is a light-sensitive screen on which the image is formed. It is a delicate
membrane having enormous number of light-sensitive cells. It converts the image formed
by the Lens into electrical impulses . These electrical impulses are then transmitted to the
brain through Optic nerves. It contains Rods and Cones.
11. Optic Nerve - These are the nerve which take the image to the brain in the form of
electric Signals
6. How Pupil Works ??
The iris makes the pupil expand or contract according to the intensity of light
around the eye.
i. When the light is bright : Iris contracts the pupil, so that less light enters the eye.
ii. When the light is dim : Iris expands the pupil so that more light enters the eye.
Example: You would have observed that when you come out of the cinema hall after
watching movie, in the bright sun light, your eyes get closed . And when you enter the hall
from the bright light, you won’be able to see but after some time you would be able to see.
Here the pupil of an eye provides a variable aperture, whose size is controlled by iris
7. Power of Accommodation
The ability of the eye lens to adjust its focal length is called power of
accommodation
Ciliary Muscles
Contract
Relax
Eye lens becomes thin
Increases the focal length
Enable us to see distant
object clearly
Eye lens becomes thick
Decreases the focal length
Enable us to see nearby object
clearly
8. A person with myopia can see nearby objects clearly but cannot see distant
objects distinctly. A person with this defect has the far point nearer than infinity.
Causes :
(i) excessive curvature of the eye lens.
(ii) elongation of the eyeball.
Corrections :
This defect can be corrected by using a concave lens of suitable power. A
concave lens of suitable power will bring the image back on to the retina and thus
the defect is corrected.
DEFECTS OF VISION AND THEIR CORRECTION
1. MYOPIA ( Near-Sightedness or Short Sightedness )
9.
10. 2. HYPERMETROPIA ( Far-Sightedness or Long-Sightedness )
A person with hypermetropia can see distant objects clearly but cannot see nearby
objects distinctly. The near point, for the person, is farther away from the normal
near point (25 cm).
Causes :
(i) The focal length of the eye lens is too long.
(ii) The eyeball has become too small.
Corrections :
This defect can be corrected by using a convex lens of appropriate power. Eye-
glasses with converging lenses provide the additional focusing power required for
forming the image on the retina
11.
12. As we become old, the power of accommodation of the eye usually
decreases, the near point gradually recedes away. This defect is
called Presbyopia.
Person may suffer from both myopia and hypermetropia.
3. Presbyopia
Reason of defect : Gradual weakening of ciliary muscles and decreasing
the flexibility of the eye lens.
Correction : Using Bifocal lens with appropriate power.Bifocal lens
consist of both concave and convex lens
13. 4. Cataract
Sometimes, the crystalline lens of people at old age becomes
milky and cloudy. This condition is called cataract. This causes
partial or complete loss of vision. It is possible to restore vision
through a cataract surgery.
14. REFRACTION OF LIGHT THROUGH A PRISM
PE – Incident ray
∠i – Angle of incidence
EF – Refracted ray
∠r – Angle of refraction
FS – Emergent ray
∠e – Angle of emergence
∠A – Angle of the prism
∠D – Angle of deviation
15.
16. The splitting of white light into its component colours when it passes
through a glass prism is called dispersion of light. The various colours are
violet, indigo, blue, green, yellow, orange, red. The sequence of colours
remembers as VIBGYOR.The band of seven colours is called the spectrum.
DISPERSION OF WHITE LIGHT BY A GLASS PRISM
18. A rainbow is a natural spectrum appearing in the sky after a rain shower It is caused
by dispersion of sunlight by tiny water droplets, present in the atmosphere. A
rainbow is always formed in a direction opposite to that of the Sun. The water
droplets act like small prisms. They refract and disperse the incident sunlight, then
reflect it internally, and finally refract it again when it comes out of the raindrop
Due to the dispersion of light and internal reflection, different colours reach the
observer’s eye.
Rainbow Formation
19. It is due to atmospheric refraction of starlight.
The temperature and density of different layers of atmosphere keeps varying.
Hence we have different medium.
Distant star act as point source of light. When the starlight enter the earth’s
atmosphere it undergoes refraction continuously, due to changing refractive
index i.e. from Rarer to denser, it bends towards the normal.
Due to this the apparent position of the star is different from actual position.
The star appears higher than its actual position.
ATMOSPHERIC REFRACTION
The refraction of light caused by the Earth’s atmosphere ( having air layers of
varying optical densities ) is called atmospheric refraction.
Twinkling of stars
20.
21. Actual sunrise happens when the sun is below the horizon in the morning. the
rays of the light from the sun below the horizon reach our eyes because of
refraction of light. similarly , the sun can be seen about few minutes after the
actual sunset. The sun is visible to us about 2 minutes before the actual sunrise,
and about 2 minutes after the actual sunset because of atmospheric refraction.
Advance sunrise and delayed sunset
22. SCATTERING OF LIGHT
The scattering of light is the phenomenon by which a beam of light is redirected in
different directions on interacting with the particles present in the medium
Tyndall Effect
Tyndall Effect deals with the phenomenon of scattering of light by colloidal particles.
(1) When a fine beam of sunlight enters a room, the particles present in the room become visible
due to scattering of light by these particles.
(2) When sunlight passes through a canopy of a dense forest, tiny water droplets in the mist
scatter light.
The colour of the scattered light depends on the size of the scattering particle. Very fine particles
scatter mainly blue light while particles of larger size scatter light of longer wavelength. If the
size of the scattering particle is large enough, then the scattered light may even appear white.
23.
24. Why is the colour of the clear Sky Blue?
The molecules of air and other fine particles in the atmosphere have size smaller
than the wavelength of visible light. These are more effective in scattering light of
shorter wavelengths at the blue end than light of longer wavelengths at the red end.
When sunlight passes through the atmosphere, the fine particles in air scatter the
blue colour (shorter wavelengths) more strongly than red. The scattered blue light
enters our eyes. If the earth had no atmosphere, there would not have been any
scattering. Then, the sky would have looked dark.