This document summarizes notable healthcare transaction trends and regulatory updates from 2010. It discusses the impact of healthcare reform on transactions, including provisions encouraging accountable care organizations. It also summarizes regulatory activity from the CMS and OIG, including the publication of the Stark Self-Referral Disclosure Protocol and OIG advisory opinions on sleep center arrangements. Additionally, it discusses two qui tam court cases, Tuomey and Bradford, that sparked discussion around the healthcare fair market value standard.