Sai Karra presented on how businesses can utilize TikTok to reach 100,000 followers. He discussed two approaches: the brand approach and the influencer approach. The influencer approach focuses on creating entertaining content that builds the influencer's personal brand and allows them to subtly promote products through word-of-mouth marketing. Karra outlined the key elements to reach 100,000 followers: script generation, content creation, iterations to improve content, and consistency in the process. With these techniques, businesses can achieve "TikTok Tranquility" - an organized monetization strategy that leads to consistent results and engaged followers.