This document summarizes Nicholas C. Zakas' presentation on high performance JavaScript. It discusses how the browser UI thread handles both UI updates and JavaScript execution sequentially. Long running JavaScript can cause unresponsive UIs. Techniques to ensure responsive UIs include limiting JavaScript execution time, using timers or web workers to break up processing, reducing repaints and reflows, and grouping style changes. Hardware acceleration and optimizing JavaScript engines have improved performance but responsive UIs still require discipline.